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Volumn 31, Issue 5, 2007, Pages 500-507

Down-regulation of IGF-IR using small, interfering, hairpin RNA (siRNA) inhibits growth of human lung cancer cell line A549 in vitro and in nude mice

Author keywords

Lung cancer; RNA interference; Type I insulin like growth factor receptor

Indexed keywords

SMALL INTERFERING RNA; SOMATOMEDIN C RECEPTOR;

EID: 34247167175     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellbi.2006.11.017     Document Type: Article
Times cited : (30)

References (32)
  • 1
    • 0036899212 scopus 로고    scopus 로고
    • RNAi and related mechanisms and their potential use for therapy
    • Agami R. RNAi and related mechanisms and their potential use for therapy. Curr Opin Chem Biol 6 (2002) 829-834
    • (2002) Curr Opin Chem Biol , vol.6 , pp. 829-834
    • Agami, R.1
  • 2
    • 0035286609 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor antagonism results in increased cytotoxicity of breast cancer cells to doxorubicin and taxol
    • Beech D.J., Parekh N., and Pang Y. Insulin-like growth factor-I receptor antagonism results in increased cytotoxicity of breast cancer cells to doxorubicin and taxol. Oncol Rep 8 (2001) 325-329
    • (2001) Oncol Rep , vol.8 , pp. 325-329
    • Beech, D.J.1    Parekh, N.2    Pang, Y.3
  • 4
    • 0034115368 scopus 로고    scopus 로고
    • Treatment of human breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor inhibits cell growth, suppresses tumorigenesis, alters the metastatic potential, and prolongs survival in vivo
    • Chernicky C.L., Yi L., Tan H., Gan S.U., and Ilan J. Treatment of human breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor inhibits cell growth, suppresses tumorigenesis, alters the metastatic potential, and prolongs survival in vivo. Cancer Gene Ther 7 (2000) 384-395
    • (2000) Cancer Gene Ther , vol.7 , pp. 384-395
    • Chernicky, C.L.1    Yi, L.2    Tan, H.3    Gan, S.U.4    Ilan, J.5
  • 5
    • 0012756249 scopus 로고    scopus 로고
    • RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase
    • Donze O., and Picard D. RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. Nucleic Acids Res 30 (2002) e46
    • (2002) Nucleic Acids Res , vol.30
    • Donze, O.1    Picard, D.2
  • 6
    • 0032146711 scopus 로고    scopus 로고
    • A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer
    • Dunn S.E., Ehrlich M., Sharp N.J., Reiss K., Solomon G., Hawkins R., et al. A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer. Cancer Res 58 (1998) 3353-3361
    • (1998) Cancer Res , vol.58 , pp. 3353-3361
    • Dunn, S.E.1    Ehrlich, M.2    Sharp, N.J.3    Reiss, K.4    Solomon, G.5    Hawkins, R.6
  • 8
    • 10344247119 scopus 로고    scopus 로고
    • A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts
    • Goetsch L., Gonzalez A., Leger O., Beck A., Pauwels P.J., Haeuw J.F., et al. A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts. Int J Cancer 113 (2005) 316-328
    • (2005) Int J Cancer , vol.113 , pp. 316-328
    • Goetsch, L.1    Gonzalez, A.2    Leger, O.3    Beck, A.4    Pauwels, P.J.5    Haeuw, J.F.6
  • 10
    • 0037206277 scopus 로고    scopus 로고
    • Treatment of advanced non-small cell lung cancer
    • Hansen H.H. Treatment of advanced non-small cell lung cancer. BMJ 325 (2002) 452-453
    • (2002) BMJ , vol.325 , pp. 452-453
    • Hansen, H.H.1
  • 11
    • 0033613356 scopus 로고    scopus 로고
    • Induction of tumor suppression and glandular differentiation of A549 lung carcinoma cells by dominant-negative IGF-I receptor
    • Jiang Y., Rom W.N., Yie T.A., Chi C.X., and Tchou-Wong K.M. Induction of tumor suppression and glandular differentiation of A549 lung carcinoma cells by dominant-negative IGF-I receptor. Oncogene 18 (1999) 6071-6077
    • (1999) Oncogene , vol.18 , pp. 6071-6077
    • Jiang, Y.1    Rom, W.N.2    Yie, T.A.3    Chi, C.X.4    Tchou-Wong, K.M.5
  • 12
    • 0031034574 scopus 로고    scopus 로고
    • Antiapoptotic signaling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt
    • Kulik G., Klippel A., and Weber M.J. Antiapoptotic signaling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Mol Cell Biol. 17 (1997) 1595-1606
    • (1997) Mol Cell Biol. , vol.17 , pp. 1595-1606
    • Kulik, G.1    Klippel, A.2    Weber, M.J.3
  • 13
    • 0033531765 scopus 로고    scopus 로고
    • Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3
    • Ma J., Pollak M.N., Giovannucci E., Chan J.M., Tao Y., Hennekens C.H., et al. Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst 91 (1999) 620-625
    • (1999) J Natl Cancer Inst , vol.91 , pp. 620-625
    • Ma, J.1    Pollak, M.N.2    Giovannucci, E.3    Chan, J.M.4    Tao, Y.5    Hennekens, C.H.6
  • 14
    • 0023870373 scopus 로고
    • Somatomedin-C/insulin-like growth factor-I is a mitogen for human small cell lung cancer
    • Macauly V.M., Teale J.D., Everard M.J., Joshi G.P., Smith I.E., and Millar J.L. Somatomedin-C/insulin-like growth factor-I is a mitogen for human small cell lung cancer. Br J Cancer 57 (1988) 91-93
    • (1988) Br J Cancer , vol.57 , pp. 91-93
    • Macauly, V.M.1    Teale, J.D.2    Everard, M.J.3    Joshi, G.P.4    Smith, I.E.5    Millar, J.L.6
  • 15
    • 0042515293 scopus 로고    scopus 로고
    • An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation
    • Maloney E.K., McLaughlin J.L., Dagdigian N.E., Garrett L.M., Connors K.M., Zhou X.M., et al. An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation. Cancer Res 63 (2003) 5073-5083
    • (2003) Cancer Res , vol.63 , pp. 5073-5083
    • Maloney, E.K.1    McLaughlin, J.L.2    Dagdigian, N.E.3    Garrett, L.M.4    Connors, K.M.5    Zhou, X.M.6
  • 17
    • 0036245628 scopus 로고    scopus 로고
    • U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells
    • Miyagishi M., and Taira K. U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nat Biotechnol 20 (2002) 497-500
    • (2002) Nat Biotechnol , vol.20 , pp. 497-500
    • Miyagishi, M.1    Taira, K.2
  • 18
    • 0037446068 scopus 로고    scopus 로고
    • Small interfering RNAs suppress the expression of endogenous and GFP-fused epidermal growth factor receptor (erbB1) and induce apoptosis in erbB1-overexpressing cells
    • Nagy P., Arndt-Jovin D.J., and Jovin T.M. Small interfering RNAs suppress the expression of endogenous and GFP-fused epidermal growth factor receptor (erbB1) and induce apoptosis in erbB1-overexpressing cells. Exp Cell Res 285 (2003) 39-49
    • (2003) Exp Cell Res , vol.285 , pp. 39-49
    • Nagy, P.1    Arndt-Jovin, D.J.2    Jovin, T.M.3
  • 19
    • 0023714574 scopus 로고
    • Insulin-like growth factor-I can mediate autocrine proliferation of human small cell lung cancer cell lines in vitro
    • Nakanishi Y., Mulshine J.L., Kasprzyk P.G., Natale R.B., Maneckjee R., Avis I., et al. Insulin-like growth factor-I can mediate autocrine proliferation of human small cell lung cancer cell lines in vitro. J Clin Invest 82 (1988) 354-359
    • (1988) J Clin Invest , vol.82 , pp. 354-359
    • Nakanishi, Y.1    Mulshine, J.L.2    Kasprzyk, P.G.3    Natale, R.B.4    Maneckjee, R.5    Avis, I.6
  • 20
    • 3142615372 scopus 로고    scopus 로고
    • The RNAi revolution
    • Novina C.D., and Sharp P.A. The RNAi revolution. Nature 430 (2004) 161-164
    • (2004) Nature , vol.430 , pp. 161-164
    • Novina, C.D.1    Sharp, P.A.2
  • 21
    • 10844296820 scopus 로고    scopus 로고
    • Silencing of the IGF1R gene enhances sensitivity to DNA-damaging agents in both PTEN wild-type and mutant human prostate cancer
    • Rochester M.A., Riedemann J., Hellawell G.O., Brewster S.F., and Macaulay V.M. Silencing of the IGF1R gene enhances sensitivity to DNA-damaging agents in both PTEN wild-type and mutant human prostate cancer. Cancer Gene Therapy 12 (2005) 90-100
    • (2005) Cancer Gene Therapy , vol.12 , pp. 90-100
    • Rochester, M.A.1    Riedemann, J.2    Hellawell, G.O.3    Brewster, S.F.4    Macaulay, V.M.5
  • 22
    • 0023686033 scopus 로고
    • Signal transduction by allosteric receptor oligomerization
    • Schlessinger J. Signal transduction by allosteric receptor oligomerization. Trends Biochem. Sci 13 (1988) 443-447
    • (1988) Trends Biochem. Sci , vol.13 , pp. 443-447
    • Schlessinger, J.1
  • 23
    • 0034495366 scopus 로고    scopus 로고
    • Insulin-like growth factor system in growth, development and carcinogenesis
    • Singh P. Insulin-like growth factor system in growth, development and carcinogenesis. J Clin Lig Assay 23 (2000) 214-232
    • (2000) J Clin Lig Assay , vol.23 , pp. 214-232
    • Singh, P.1
  • 25
    • 27744526775 scopus 로고    scopus 로고
    • Targeted therapy for non-small cell lung cancer
    • Toloza E.M., and D'Amico T.A. Targeted therapy for non-small cell lung cancer. Semin Thorac Cardiovasc Surg 17 (2005) 199-204
    • (2005) Semin Thorac Cardiovasc Surg , vol.17 , pp. 199-204
    • Toloza, E.M.1    D'Amico, T.A.2
  • 26
    • 0028270718 scopus 로고
    • Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation
    • Troppmair J., Bruder J.T., Munoz H., Lloyd P.A., Kyriakis J., Banerjee P., et al. Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation. J Biol Chem 9 (1994) 7030-7035
    • (1994) J Biol Chem , vol.9 , pp. 7030-7035
    • Troppmair, J.1    Bruder, J.T.2    Munoz, H.3    Lloyd, P.A.4    Kyriakis, J.5    Banerjee, P.6
  • 27
    • 26944499005 scopus 로고    scopus 로고
    • The therapeutic potential of RNA interference
    • Uprichard S.L. The therapeutic potential of RNA interference. FEBS Lett 579 (2005) 5996-6007
    • (2005) FEBS Lett , vol.579 , pp. 5996-6007
    • Uprichard, S.L.1
  • 28
    • 0024521844 scopus 로고
    • Signal transduction by the platelet-derived growth factor receptor
    • Williams L.T. Signal transduction by the platelet-derived growth factor receptor. Science 243 (1989) 1564-1570
    • (1989) Science , vol.243 , pp. 1564-1570
    • Williams, L.T.1
  • 29
    • 0029744687 scopus 로고    scopus 로고
    • Activation of the insulin-like growth factor-I receptor inhibits tumor necrosis factor-induced cell death
    • Wu Y., Tewari M., Cui S., and Rubin R. Activation of the insulin-like growth factor-I receptor inhibits tumor necrosis factor-induced cell death. J Cell Physiol 168 (1996) 499-509
    • (1996) J Cell Physiol , vol.168 , pp. 499-509
    • Wu, Y.1    Tewari, M.2    Cui, S.3    Rubin, R.4
  • 30
    • 0023100261 scopus 로고
    • Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor
    • Yarden Y., and Schlessinger J. Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor. Biochemistry 26 (1987) 1443-1451
    • (1987) Biochemistry , vol.26 , pp. 1443-1451
    • Yarden, Y.1    Schlessinger, J.2
  • 31
    • 0023942517 scopus 로고
    • Growth factor receptor tyrosine kinases
    • Yarden Y., and Ullrich A. Growth factor receptor tyrosine kinases. Annu Rev Biochem 57 (1988) 443-478
    • (1988) Annu Rev Biochem , vol.57 , pp. 443-478
    • Yarden, Y.1    Ullrich, A.2
  • 32
    • 0034877670 scopus 로고    scopus 로고
    • RNA interference: listening to the sound of silence
    • Zamore P.D. RNA interference: listening to the sound of silence. Nat Struct Biol 8 (2001) 746-750
    • (2001) Nat Struct Biol , vol.8 , pp. 746-750
    • Zamore, P.D.1


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