-
1
-
-
0346206633
-
A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro
-
Salmon WD, Daughaday WH. A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro. J Lab Clin Med 1957;49:825-836
-
(1957)
J Lab Clin Med
, vol.49
, pp. 825-836
-
-
Salmon, W.D.1
Daughaday, W.H.2
-
2
-
-
0032559272
-
Plasma insulin-like growth factor-I and prostate cancer risk: A prospective study
-
DOI 10.1126/science.279.5350.563
-
Chan JM, Stampfer MJ, Giovannucci E, Gann PH, Ma J, Wilkinson P, Hennekens CH, Pollak M. Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study. Science 1998;279:563-566 (Pubitemid 28067285)
-
(1998)
Science
, vol.279
, Issue.5350
, pp. 563-566
-
-
Chan, J.M.1
Stampfer, M.J.2
Giovannucci, E.3
Gann, P.H.4
Ma, J.5
Wilkinson, P.6
Hennekens, C.H.7
Pollak, M.8
-
3
-
-
1942436958
-
Insulin-like growth factor-I, IGF binding protein-3, and cancer risk: Systematic review and meta-regression analysis
-
Renehan AG, Zwahlen M, C M, O'Dwyer ST, Shalet SM, Egger M. Insulin-like growth factor-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. Lancet 2004;363:1346-1353
-
(2004)
Lancet
, vol.363
, pp. 1346-1353
-
-
Renehan, A.G.1
Zwahlen, M.2
C, M.3
O'Dwyer, S.T.4
Shalet, S.M.5
Egger, M.6
-
4
-
-
43349088787
-
Targeting the type 1 insulin-like growth factor receptor as a treatment for cancer
-
DOI 10.1517/14728222.12.5.589
-
Yuen JSP, Macaulay VM. Targeting the type 1 insulin-like growth factor receptor as a treatment for cancer. Exp Opinion Ther Targets 2008;12:589-603 (Pubitemid 351699478)
-
(2008)
Expert Opinion on Therapeutic Targets
, vol.12
, Issue.5
, pp. 589-603
-
-
Yuen, J.S.P.1
Macaulay, V.M.2
-
5
-
-
0034693756
-
The contradictions of the insulin-like growth factor 1 receptor
-
Baserga R. The contradictions of the insulin-like growth factor 1 receptor. Oncogene 2000;19:5574-5581
-
(2000)
Oncogene
, vol.19
, pp. 5574-5581
-
-
Baserga, R.1
-
6
-
-
0029692479
-
The role of the insulin-like growth factor system in human cancer
-
Werner H, LeRoith D. The role of the insulin-like growth factor system in human cancer. Adv Cancer Res 1996;68:183-223
-
(1996)
Adv Cancer Res
, vol.68
, pp. 183-223
-
-
Werner, H.1
LeRoith, D.2
-
7
-
-
0027537988
-
Up-regulation of insulin-like growth factor-I (IGF-I) receptor gene expression in patients with reduced serum IGF-I levels
-
Eshet R, Werner H, Klinger B, Silbergeld A, Laron Z, LeRoith D, Roberts CT, Jr. Up-regulation of insulin-like growth factor-I (IGF-I) receptor gene expression in patients with reduced serum IGF-I levels. J Mol Endocrinol 1993;10:115-120 (Pubitemid 23100293)
-
(1993)
Journal of Molecular Endocrinology
, vol.10
, Issue.2
, pp. 115-120
-
-
Eshet, R.1
Werner, H.2
Klinger, B.3
Silbergeld, A.4
Laron, Z.5
LeRoith, D.6
Roberts Jr., C.T.7
-
8
-
-
33846846385
-
Estrogen receptor regulates insulin-like growth factor-I receptor gene expression in breast tumor cells: Involvement of transcription factor Sp1
-
DOI 10.1677/joe.1.07016
-
Maor S, Mayer D, Yarden RI, Lee AV, Sarfstein R, Werner H, Papa MZ. Estrogen receptor regulates insulin-like growth factor-I receptor gene expression in breast tumor cells: involvement of transcription factor Sp1. J Endocrinol 2006;191:605-612 (Pubitemid 46210286)
-
(2006)
Journal of Endocrinology
, vol.191
, Issue.3
, pp. 605-612
-
-
Maor, S.1
Mayer, D.2
Yarden, R.I.3
Lee, A.V.4
Sarfstein, R.5
Werner, H.6
Papa, M.Z.7
-
9
-
-
0028340736
-
Platelet-derived growth factor increases the activity of the promoter of the IGF-I receptor gene
-
Rubini M, Werner H, Gandini E, Roberts CT, Jr, LeRoith D, Baserga R. Platelet-derived growth factor increases the activity of the promoter of the IGF-I receptor gene. Exp Cell Res 1994;211:374-379
-
(1994)
Exp Cell Res
, vol.211
, pp. 374-379
-
-
Rubini, M.1
Werner, H.2
Gandini, E.3
Roberts Jr., C.T.4
LeRoith, D.5
Baserga, R.6
-
10
-
-
0031051392
-
Differential regulation of IGF-I receptor gene expression by IGF-I and basic fibroblast growth factor
-
Hernandez-Sanchez C, Werner H, Roberts CT, Jr, Woo EJ, Hun DW, Rosenthal SM, LeRoith D. Differential regulation of IGF-I receptor gene expression by IGF-I and basic fibroblast growth factor. J Biol Chem 1997;272:4663-4670
-
(1997)
J Biol Chem
, vol.272
, pp. 4663-4670
-
-
Hernandez-Sanchez, C.1
Werner, H.2
Roberts Jr., C.T.3
Woo, E.J.4
Hun, D.W.5
Rosenthal, S.M.6
LeRoith, D.7
-
11
-
-
0025028901
-
Cellular pattern of insulin-like growth factor I (IGF-I) and type I IGF receptor gene expression in early organogenesis: Comparison with IGF-II gene expression
-
Bondy CA, Werner H, Roberts CT, Jr, LeRoith D. Cellular pattern of insulin-like growth factor I (IGF-I) and type I IGF receptor gene expression in early organogenesis: comparison with IGF-II gene expression. Mol Endocrinol 1990;4:1386-1398
-
(1990)
Mol Endocrinol
, vol.4
, pp. 1386-1398
-
-
Bondy, C.A.1
Werner, H.2
Roberts Jr., C.T.3
LeRoith, D.4
-
12
-
-
13444304371
-
IGF, IGF receptor and overgrowth syndromes
-
Bentov I, Werner H. IGF, IGF receptor and overgrowth syndromes. Pediatr Endocrinol Rev 2004;1:352-360
-
(2004)
Pediatr Endocrinol Rev
, vol.1
, pp. 352-360
-
-
Bentov, I.1
Werner, H.2
-
13
-
-
0037300604
-
The IGF-I receptor gene: A molecular target for disrupted transcription factors
-
Werner H, Roberts CT, Jr. The IGF-I receptor gene: a molecular target for disrupted transcription factors. Genes, Chromosomes and Cancer 2003;36:113-120
-
(2003)
Genes, Chromosomes and Cancer
, vol.36
, pp. 113-120
-
-
Werner, H.1
Roberts Jr., C.T.2
-
14
-
-
0034693680
-
Down-regulation of insulin-like growth factor-I receptor and insulin receptor substrate-1 expression in advanced human breast cancer
-
Schnarr B, Strunz K, Ohsam J, Benner A, Wacker J, Mayer D. Down-regulation of insulin-like growth factor-I receptor and insulin receptor substrate-1 expression in advanced human breast cancer. Int J Cancer 2000;89:506-513
-
(2000)
Int J Cancer
, vol.89
, pp. 506-513
-
-
Schnarr, B.1
Strunz, K.2
Ohsam, J.3
Benner, A.4
Wacker, J.5
Mayer, D.6
-
15
-
-
35148841175
-
Elevated insulin-like growth factor-I receptor (IGF-IR) levels in primary breast tumors associated with BRCA1 mutations
-
DOI 10.1016/j.canlet.2007.07.019, PII S0304383507003436
-
Maor S, Yosepovich A, Papa MZ, Yarden RI, Mayer D, Friedman E, Werner H. Elevated insulin-like growth factor-I receptor (IGF-IR) levels in primary breast tumors associated with BRCA1 mutations. Cancer Lett 2007;257:236-243 (Pubitemid 47538827)
-
(2007)
Cancer Letters
, vol.257
, Issue.2
, pp. 236-243
-
-
Maor, S.1
Yosepovich, A.2
Papa, M.Z.3
Yarden, R.I.4
Mayer, D.5
Friedman, E.6
Werner, H.7
-
16
-
-
0029826841
-
Protein and mRNA for the type 1 insulin-like growth factor (IGF) receptor is decreased and IGF-II mRNA is increased in human prostate carcinoma compared to benign prostate epithelium
-
Tennant MK, Thrasher JB, Twomey PA, Drivdahl RH, Birnbaum RS, Plymate SR. Protein and mRNA for the type 1 insulin-like growth factor (IGF) receptor is decreased and IGF-II mRNA is increased in human prostate carcinoma compared to benign prostate epithelium. J Clin Endocrinol Metab 1996;81:3774-3782
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 3774-3782
-
-
Tennant, M.K.1
Thrasher, J.B.2
Twomey, P.A.3
Drivdahl, R.H.4
Birnbaum, R.S.5
Plymate, S.R.6
-
17
-
-
0037092971
-
Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease
-
Hellawell GO, Turner GD, Davies DR, Poulsom R, Brewster SF, Macaulay VM. Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease. Cancer Res 2002;62:2942-2950
-
(2002)
Cancer Res
, vol.62
, pp. 2942-2950
-
-
Hellawell, G.O.1
Turner, G.D.2
Davies, D.R.3
Poulsom, R.4
Brewster, S.F.5
Macaulay, V.M.6
-
18
-
-
27544501420
-
Up-regulation of insulin-like growth factor axis components in human primary prostate cancer correlates with tumor grade
-
Liao Y, Abel U, Grobholz R, Hermani A, Trojan L, Angel P, Mayer D. Up-regulation of insulin-like growth factor axis components in human primary prostate cancer correlates with tumor grade. Human Pathol 2005;36:1186-1196
-
(2005)
Human Pathol
, vol.36
, pp. 1186-1196
-
-
Liao, Y.1
Abel, U.2
Grobholz, R.3
Hermani, A.4
Trojan, L.5
Angel, P.6
Mayer, D.7
-
19
-
-
0344874656
-
IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation
-
Group IGRIS
-
Abuzzahab MJ, Schneider A, Goddard A, Grigorescu F, Lautier C, Keller E, Kiess W, Klammt J, Kratzsch J, Osgood D, Pfaffle R, Raile K, Seidel B, Smith RJ, Chernausek SD, Group IGRIS. IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation. New England J Med 2003;349:2211-2222
-
(2003)
New England J Med
, vol.349
, pp. 2211-2222
-
-
Abuzzahab, M.J.1
Schneider, A.2
Goddard, A.3
Grigorescu, F.4
Lautier, C.5
Keller, E.6
Kiess, W.7
Klammt, J.8
Kratzsch, J.9
Osgood, D.10
Pfaffle, R.11
Raile, K.12
Seidel, B.13
Smith, R.J.14
Chernausek, S.D.15
-
20
-
-
18744404492
-
Overgrowth and trisomy 15q26.1-qter including the IGF1 receptor gene: Report of two families and review of the literature
-
Faivre L, Gosset P, Comier-Daire V, Odent S, Amiel J, Giurgea L, Nassogne MC, Pasquier L, Munnich A, Romana S, Prieur M, Vekemans M, De Blois MC, Turleau C. Overgrowth and trisomy 15q26.1-qter including the IGF1 receptor gene: report of two families and review of the literature. Eur J Hum Genet 2002;10:699-706
-
(2002)
Eur J Hum Genet
, vol.10
, pp. 699-706
-
-
Faivre, L.1
Gosset, P.2
Comier-Daire, V.3
Odent, S.4
Amiel, J.5
Giurgea, L.6
Nassogne, M.C.7
Pasquier, L.8
Munnich, A.9
Romana, S.10
Prieur, M.11
Vekemans, M.12
De Blois, M.C.13
Turleau, C.14
-
21
-
-
0029043193
-
Hemizygosity at the insulin-like growth factor I receptor (IGF1R) locus and growth failure in the ring chromosome 15 syndrome
-
Peoples R, Milatovich A, Francke U. Hemizygosity at the insulin-like growth factor I receptor (IGF1R) locus and growth failure in the ring chromosome 15 syndrome. Cytogenet Cell Genetics 1995;70:228-234
-
(1995)
Cytogenet Cell Genetics
, vol.70
, pp. 228-234
-
-
Peoples, R.1
Milatovich, A.2
Francke, U.3
-
22
-
-
0028080990
-
C Phosphorylation and activation of the IGF-I receptor in src-transformed cells
-
Peterson JE, Jelinek T, Kaleko M, Siddle K, Weber MJ. C phosphorylation and activation of the IGF-I receptor in src-transformed cells. J Biol Chem 1994;269:27315-27321 (Pubitemid 24346553)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.44
, pp. 27315-27321
-
-
Peterson, J.E.1
Jelinek, T.2
Kaleko, M.3
Siddle, K.4
Weber, M.J.5
-
23
-
-
0026336492
-
The protooncogene c-myb increases the expression of insulin-like growth factor I and insulin-like growth factor I receptor messenger RNAs by a transcriptional mechanism
-
Reiss K, Ferber A, Travail S, Porcu P, Phillips PD, Baserga R. The protooncogene c-myb increases the expression of insulin-like growth factor I and insulin-like growth factor I receptor messenger RNAs by a transcriptional mechanism. Cancer Res 1991;51:5997-6000
-
(1991)
Cancer Res
, vol.51
, pp. 5997-6000
-
-
Reiss, K.1
Ferber, A.2
Travail, S.3
Porcu, P.4
Phillips, P.D.5
Baserga, R.6
-
24
-
-
0037464450
-
BRCA1-Sp1 interactions in transcriptional regulation of the IGF-IR gene
-
DOI 10.1016/S0014-5793(03)00315-6
-
Abramovitch S, Glaser T, Ouchi T, Werner H. BRCA1-Sp1 interactions in transcriptional regulation of the IGF-IR gene. FEBS Lett 2003;541:149-154 (Pubitemid 36428934)
-
(2003)
FEBS Letters
, vol.541
, Issue.1-3
, pp. 149-154
-
-
Abramovitch, S.1
Glaser, T.2
Ouchi, T.3
Werner, H.4
-
25
-
-
63449121864
-
Tumor suppressor BRCA1 is expressed in prostate cancer and control IGF1-R gene transcription in an androgen receptor-dependent manner
-
Schayek H, Haugk K, Sun S, True LD, Plymate SR, Werner H. Tumor suppressor BRCA1 is expressed in prostate cancer and control IGF1-R gene transcription in an androgen receptor-dependent manner. Clin Cancer Res 2009;15:1558-1565
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1558-1565
-
-
Schayek, H.1
Haugk, K.2
Sun, S.3
True, L.D.4
Plymate, S.R.5
Werner, H.6
-
26
-
-
34948858983
-
The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renat carcinoma
-
Yuen JSP, Cockman ME, Sullivan M, Protheroe A, Turner GDH, Roberts IS, Pugh CW, Werner H, Macaulay VM. The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renat carcinoma. Oncogene 2007;26:6499-6508
-
(2007)
Oncogene
, vol.26
, pp. 6499-6508
-
-
Yuen, J.S.P.1
Cockman, M.E.2
Sullivan, M.3
Protheroe, A.4
Turner, G.D.H.5
Roberts, I.S.6
Pugh, C.W.7
Werner, H.8
Macaulay, V.M.9
-
27
-
-
0029757120
-
Wild type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene
-
Werner H, Karnieli E, Rauscher FJ, III, LeRoith D. Wild type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene. Proc Natl Acad Sci USA 1996;93:8318-8323
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8318-8323
-
-
Werner, H.1
Karnieli, E.2
Rauscher III, F.J.3
LeRoith, D.4
-
28
-
-
0037474216
-
WT1-p53 interactions in IGF-I receptor gene regulation
-
Idelman G, Glaser T, Roberts CT, Jr, Werner H. WT1-p53 interactions in IGF-I receptor gene regulation. J Biol Chem 2003;278:3474-3482
-
(2003)
J Biol Chem
, vol.278
, pp. 3474-3482
-
-
Idelman, G.1
Glaser, T.2
Roberts Jr., C.T.3
Werner, H.4
-
29
-
-
28044468153
-
The p53-family members p63 and p73 inhibit insulin-like growth factor-I receptor gene expression in colon cancer cells
-
Nahor I, Abramovitch S, Engeland K, Werner H. The p53-family members p63 and p73 inhibit insulin-like growth factor-I receptor gene expression in colon cancer cells. Growth Hormone IGF Res 2005;15:388-396
-
(2005)
Growth Hormone IGF Res
, vol.15
, pp. 388-396
-
-
Nahor, I.1
Abramovitch, S.2
Engeland, K.3
Werner, H.4
-
30
-
-
33746051671
-
The insulin-like growth factor-I receptor gene: A downstream target for oncogene and tumor suppressor action
-
DOI 10.1016/j.tem.2006.06.007, PII S1043276006001044
-
Werner H, Maor S. The insulin-like growth factor-I receptor gene: a downstream target for oncogene and tumor suppressor action. Trends Endocrinol Metab 2006;17:236-242 (Pubitemid 44080616)
-
(2006)
Trends in Endocrinology and Metabolism
, vol.17
, Issue.6
, pp. 236-242
-
-
Werner, H.1
Maor, S.2
|