Cell-based analysis of structure-function activity of threonine aspartase 1

Journal of Biological Chemistry

Volumn 286, Issue 4, 2011, Pages 3007-3017

  Bier, Carolin ^a   Knauer, Shirley K ^b   Klapthor, Alexander ^a   Schweitzer, Andrea ^a   Rekik, Alexander ^a   Krämer, Oliver H ^c   Marschalek, Rolf ^d   Stauber, Roland H ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTASE; CELL-BASED; CELLULAR ASSAYS; CLEAVAGE SITES; FULL-LENGTH PROTEINS; IN-VIVO; INTRACELLULAR SUBSTRATE; MODULAR SENSORS; NUCLEAR ACCUMULATION; NUCLEAR PROTEINS; NUCLEAR RNA; PROTEOLYTIC CLEAVAGE; PROTEOLYTIC PROCESSING; RECOGNITION SEQUENCE; SOLID TUMORS; SPATIAL REQUIREMENTS;

AMINO ACIDS; ASSAYS; BIOINFORMATICS; CELL CULTURE; ENZYME ACTIVITY; RNA; SUBSTRATES;

BIOSENSORS;

THREONINE ASPARTASE 1; THREONINE PROTEINASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CELL ASSAY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYMIC BIOSENSOR; HUMAN; HYDROPHOBICITY; IN VIVO STUDY; MOLECULAR DYNAMICS; MUTAGENESIS; OPEN READING FRAME; PLASMID; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION;

ANIMALS; BIOSENSING TECHNIQUES; CELL LINE; CELL NUCLEUS; CYTOPLASM; ENDOPEPTIDASES; GENE EXPRESSION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MICE; MUTATION; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 78951494461     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.161646     Document Type: Article

References (48)

1. Overall, C. M., and Dean, R. A. (2006) Cancer Metastasis Rev. 25, 69-75
2. Knauer, S. K., Moodt, S., Berg, T., Liebel, U., Pepperkok, R., and Stauber, R. H. (2005) Traffic 6, 594-606
3. Turk, B. (2006) Nat. Rev. Drug Discov. 5, 785-799
4. Hsieh, J. J., Cheng, E. H., and Korsmeyer, S. J. (2003) Cell 115, 293-303
5. Khan, J. A., Dunn, B. M., and Tong, L. (2005) Structure 13, 1443-1452
6. Takeda, S., Chen, D. Y., Westergard, T. D., Fisher, J. K., Rubens, J. A., Sasagawa, S., Kan, J. T., Korsmeyer, S. J., Cheng, E. H., and Hsieh, J. J. (2006) Genes Dev. 20, 2397-2409
7. Liu, H., Cheng, E. H., and Hsieh, J. J. (2007) Genes Dev. 21, 2385-2398
8. Marschalek, R. (2010) FEBS J. 277, 1822-1831
9. Meyer, C., Schneider, B., Jakob, S., Strehl, S., Attarbaschi, A., Schnittger, S., Schoch, C., Jansen, M. W., van Dongen, J. J., den Boer, M. L., Pieters, R., Ennas, M. G., Angelucci, E., Koehl, U., Greil, J., Griesinger, F., Zur Stadt, U., Eckert, C., Szczepañski, T., Niggli, F. K., Schäfer, B. W., Kempski, H., Brady, H. J., Zuna, J., Trka, J., Nigro, L. L., Biondi, A., Delabesse, E., Macintyre, E., Stanulla, M., Schrappe, M., Haas, O. A., Burmeister, T., Dingermann, T., Klingebiel, T., and Marschalek, R. (2006) Leukemia 20, 777-784
10. Capotosti, F., Hsieh, J. J., and Herr, W. (2007) Mol. Cell. Biol. 27, 7063-7072
11. Hsieh, J. J., Ernst, P., Erdjument-Bromage, H., Tempst, P., and Korsmeyer, S. J. (2003) Mol. Cell. Biol. 23, 186-194
12. Gaussmann, A., Wenger, T., Eberle, I., Bursen, A., Bracharz, S., Herr, I., Dingermann, T., and Marschalek, R. (2007) Oncogene 26, 3352-3363
13. Zhou, H., Spicuglia, S., Hsieh, J. J., Mitsiou, D. J., Høiby, T., Veenstra, G. J., Korsmeyer, S. J., and Stunnenberg, H. G. (2006) Mol. Cell. Biol. 26, 2728-2735
14. Lee, J. T., Chen, D. Y., Yang, Z., Ramos, A. D., Hsieh, J. J., and Bogyo, M. (2009) Bioorg. Med. Chem. Lett. 19, 5086-5090
15. Fetz, V., Knauer, S. K., Bier, C., Kriess, J. P., and Stauber, R. H. (2009) Sensors 7, 5423-5445
16. Knauer, S. K., Bier, C., Habtemichael, N., and Stauber, R. H. (2006) EMBO Rep. 7, 1259-1265
17. Knauer, S. K., Bier, C., Schlag, P., Fritzmann, J., Dietmaier, W., Rödel, F., Klein-Hitpass, L., Kovács, A. F., Döring, C., Hansmann, M. L., Hofmann, W. K., Kunkel, M., Brochhausen, C., Engels, K., Lippert, B. M., Mann, W., and Stauber, R. H. (2007) Cell Cycle 6, 1502-1509
18. Engels, K., Knauer, S. K., Metzler, D., Simf, C., Struschka, O., Bier, C., Mann, W., Kovács, A. F., and Stauber, R. H. (2007) J. Pathol. 211, 532-540
19. Engels, K., Knauer, S. K., Loibl, S., Fetz, V., Harter, P., Schweitzer, A., Fisseler-Eckhoff, A., Kommoss, F., Hanker, L., Nekljudova, V., Hermanns, I., Kleinert, H., Mann, W., du Bois, A., and Stauber, R. H. (2008) Cancer Res. 68, 5159-5166
20. Heger, P., Lohmaier, J., Schneider, G., Schweimer, K., and Stauber, R. H. (2001) Traffic 2, 544-555
21. Schlingemann, J., Habtemichael, N., Ittrich, C., Toedt, G., Kramer, H., Hambek, M., Knecht, R., Lichter, P., Stauber, R., and Hahn, M. (2005) Lab. Invest. 85, 1024-1039
22. Knauer, S. K., and Stauber, R. H. (2005) Anal. Chem. 77, 4815-4820
23. Knauer, S. K., Krämer, O. H., Knösel, T., Engels, K., Rödel, F., Kovács, A. F., Dietmaier, W., Klein-Hitpass, L., Habtemichael, N., Schweitzer, A., Brieger, J., Rödel, C., Mann, W., Petersen, I., Heinzel, T., and Stauber, R. H. (2007) FASEB J. 21, 207-216
24. Knauer, S. K., Carra, G., and Stauber, R. H. (2005) Mol. Cell. Biol. 25, 2573-2582
25. Jun, L., Frints, S., Duhamel, H., Herold, A., Abad-Rodrigues, J., Dotti, C., Izaurralde, E., Marynen, P., and Froyen, G. (2001) Curr. Biol. 11, 1381-1391
26. van Deursen, D., van Leeuwen, M., Vaulont, S., Jansen, H., and Verhoeven, A. J. (2009) Biochim. Biophys. Acta 1791, 229-237
27. Gossen, M., Freundlieb, S., Bender, G., Müller, G., Hillen, W., and Bujard, H. (1995) Science 268, 1766-1769
28. Fetz, V., Bier, C., Habtemichael, N., Schuon, R., Schweitzer, A., Kunkel, M., Engels, K., Kovács, A. F., Schneider, S., Mann, W., Stauber, R. H., and Knauer, S. K. (2009) Int. J. Cancer 124, 2033-2041
29. Krämer, O. H., Knauer, S. K., Greiner, G., Jandt, E., Reichardt, S., Gührs, K. H., Stauber, R. H., Böhmer, F. D., and Heinzel, T. (2009) Genes Dev. 23, 223-235
30. Krämer, O. H., Knauer, S. K., Zimmermann, D., Stauber, R. H., and Heinzel, T. (2008) Oncogene 27, 732-740
31. Dahlquist, K. D. (2004) Curr. Protoc. Bioinformatics 7.5, 1-26
32. Lai, D., Sakkas, D., and Huang, Y. (2006) RNA 12, 1446-1449
33. Marg, A., Shan, Y., Meyer, T., Meissner, T., Brandenburg, M., and Vinkemeier, U. (2004) J. Cell Biol. 165, 823-833
34. Schilling, O., and Overall, C. M. (2008) Nat. Biotechnol. 26, 685-694
35. López-Otín, C., and Overall, C. M. (2002) Nat. Rev. Mol. Cell Biol. 3, 509-519
36. Tretyakova, I., Zolotukhin, A. S., Tan, W., Bear, J., Propst, F., Ruthel, G., and Felber, B. K. (2005) J. Biol. Chem. 280, 31981-31990
37. Yokoyama, A., Kitabayashi, I., Ayton, P. M., Cleary, M. L., and Ohki, M. (2002) Blood 100, 3710-3718
38. Bursen, A., Moritz, S., Gaussmann, A., Moritz, S., Dingermann, T., and Marschalek, R. (2004) Oncogene 23, 6237-6249
39. Bursen, A., Schwabe, K., Ruster, B., Henschler, R., Ruthardt, M., Dingermann, T., and Marschalek, R. (2010) Blood 115, 3570-3579
40. Taki, T., Akiyama, M., Saito, S., Ono, R., Taniwaki, M., Kato, Y., Yuza, Y., Eto, Y., and Hayashi, Y. (2005) Oncogene 24, 5191-5197
41. Zadro, C., Alemanno, M. S., Bellacchio, E., Ficarella, R., Donaudy, F., Melchionda, S., Zelante, L., Rabionet, R., Hilgert, N., Estivill, X., Van Camp, G., Gasparini, P., and Carella, M. (2009) Biochim. Biophys. Acta 1792, 27-32
42. Jacob, B., Osato, M., Yamashita, N., Wang, C. Q., Taniuchi, I., Littman, D. R., Asou, N., and Ito, Y. (2010) Blood 115, 1610-1620
43. Eldridge, A. G., Loktev, A. V., Hansen, D. V., Verschuren, E. W., Reimann, J. D., and Jackson, P. K. (2006) Cell 124, 367-380
44. Ocejo-Garcia, M., Baokbah, T. A., Ashurst, H. L., Cowlishaw, D., Soomro, I., Coulson, J. M., and Woll, P. J. (2005) J. Pathol. 206, 151-159
45. Landa, I., Ruiz-Llorente, S., Montero-Conde, C., Inglada-Pérez, L., Schiavi, F., Leskelä, S., Pita, G., Milne, R., Maravall, J., Ramos, I., Andía, V., Rodríguez-Poyo, P., Jara-Albarrán, A., Meoro, A., del Peso, C., Arribas, L., Iglesias, P., Caballero, J., Serrano, J., Picó, A., Pomares, F., Giménez, G., López-Mondéjar, P., Castello, R., Merante-Boschin, I., Pelizzo, M. R., Mauricio, D., Opocher, G., Rodríguez-Antona, C., González-Neira, A., Matías-Guiu, X., Santisteban, P., and Robledo, M. (2009) PLoS Genet. 5, e1000637
46. Chen, N., Szentirmay, M. N., Pawar, S. A., Sirito, M., Wang, J., Wang, Z., Zhai, Q., Yang, H. X., Peehl, D. M., Ware, J. L., and Sawadogo, M. (2006) Oncogene 25, 579-587
47. Høiby, T., Zhou, H., Mitsiou, D. J., and Stunnenberg, H. G. (2007) Biochim. Biophys. Acta 1769, 429-436
48. Dubovsky, J. A., McNeel, D. G., Powers, J. J., Gordon, J., Sotomayor, E. M., and Pinilla-Ibarz, J. A. (2009) Clin. Cancer Res. 15, 3406-3415