Role of IL-18 in overt pain-like behaviour in mice

European Journal of Pharmacology

Volumn 588, Issue 2-3, 2008, Pages 207-212

  Verri Jr , Waldiceu A ^a   Cunha, Thiago M ^a   Magro, Danilo A ^a   Domingues, Andressa C ^a   Vieira, Silvio M ^a   Souza, Guilherme R ^a   Liew, Foo Y ^b   Ferreira, Sérgio H ^a   Cunha, Fernando Q ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

(interferon ); Endothelin; Hyperalgesia; IFN ; IL 18 (Interleukin 18); Inflammation; Nociception; Overt pain; Pain; PGE2

Indexed keywords

ACETIC ACID; BOSENTAN; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; GAMMA INTERFERON; INDOMETACIN; INTERLEUKIN 18; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCIN?; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; PHENYLQUINONE; PROSTANOID;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BAGG ALBINO MOUSE; CONTROLLED STUDY; DOSE RESPONSE; EXPERIMENTAL MODEL; HYPERALGESIA; MOUSE; NONHUMAN; PAIN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; WRITHING TEST;

ANIMALS; BENZOQUINONES; INTERFERON TYPE II; INTERLEUKIN-18; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PAIN; PROSTAGLANDINS; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B;

EID: 44649163816     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.04.010     Document Type: Article

References (42)

1. Arantes R.M., Marche H.H., Bahia M.T., Cunha F.Q., Rossi M.A., and Silva J.S. Interferon-gamma-induced nitric oxide causes intrinsic intestinal denervation in Trypanosoma cruzi-infected mice. Am. J. Pathol. 164 (2004) 1361-1368
2. Berkenkopf J.W., and Weichman B.M. Production of prostacyclin in mice following intraperitoneal injection of acetic acid, phenylbenzoquinone and zymosan: its role in the writhing response. Prostaglandins 36 (1988) 693-709
3. Collier H.O., Dinneen L.C., Johnson C.A., and Schneider C. The abdominal constriction response and its suppression by analgesic drugs in the mouse. Br. J. Pharmacol. Chemother. 32 (1968) 295-310
4. Cunha T.M., Verri Jr. W.A., Fukada S.Y., Guerrero A.T., Santodomingo-Garzon T., Poole S., Parada C.A., Ferreira S.H., and Cunha F.Q. TNF-alpha and IL-1beta mediate inflammatory hypernociception in mice triggered by B1 but not B2 kinin receptor. Eur. J. Pharmacol. 573 (2007) 221-229
5. Dubuisson D., and Dennis S.G. The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats. Pain 4 (1977) 161-174
6. Emele J.F., and Shanaman J.E. Analgesic activity of namoxyrate (2-[4-biphenylyl] butyric acid 2-dimethylaminoethanol salt). Arch. Int. Pharmacodyn. Ther. 170 (1967) 99-107
7. Ferreira S.H., Lorenzetti B.B., Bristow A.F., and Poole S. Interleukin-1 beta as a potent hyperalgesic agent antagonized by a tripeptide analogue. Nature 334 (1988) 698-700
8. Ferreira S.H., Nakamura M., and de Abreu Castro M.S. The hyperalgesic effects of prostacyclin and prostaglandin E2. Prostaglandins 16 (1978) 31-37
9. Ferreira S.H., Romitelli M., and de Nucci G. Endothelin-1 participation in overt and inflammatory pain. J. Cardiovasc. Pharmacol. 13 Suppl 5 (1989) S220-S222
10. Goto K., Ochi H., Yasunaga Y., Matsuyuki H., Imayoshi T., Kusuhara H., and Okumoto T. Analgesic effect of mofezolac, a non-steroidal anti-inflammatory drug, against phenylquinone-induced acute pain in mice. Prostaglandins Other Lipid Mediat. 56 (1998) 245-254
11. Griswold D.E., Douglas S.A., Martin L.D., Davis T.G., Davis L., Ao Z., Luttmann M.A., Pullen M., Nambi P., Hay D.W., and Ohlstein E.H. Endothelin B receptor modulates inflammatory pain and cutaneous inflammation. Mol. Pharmacol. 56 (1999) 807-812
12. Guerrero A.T., Verri Jr. W.A., Cunha T.M., Silva T.A., Rocha F.A., Ferreira S.H., Cunha F.Q., and Parada C.A. Hypernociception elicited by tibio-tarsal joint flexion in mice: a novel experimental arthritis model for pharmacological screening. Pharmacol. Biochem. Behav. 84 (2006) 244-251
13. Hargreaves K., Dubner R., Brown F., Flores C., and Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32 (1988) 77-88
14. Kuranaga N., Kinoshita M., Kawabata T., Habu Y., Shinomiya N., and Seki S. Interleukin-18 protects splenectomized mice from lethal Streptococcus pneumoniae sepsis independent of interferon-gamma by inducing IgM production. J. Infect. Dis. 194 (2006) 993-1002
15. Kusuhara H., Matsuyuki H., and Okumoto T. Involvement of prostaglandins produced by cyclooxygenase-1 in murine visceronociception induced by phenylquinone. Prostaglandins Other Lipid Mediat. 55 (1998) 43-49
16. Leung B.P., McInnes I.B., Esfandiari E., Wei X.Q., and Liew F.Y. Combined effects of IL-12 and IL-18 on the induction of collagen-induced arthritis. J. Immunol. 164 (2000) 6495-6502
17. McInnes I.B., Gracie J.A., Leung B.P., Wei X.Q., and Liew F.Y. Interleukin 18: a pleiotropic participant in chronic inflammation. Immunol. Today 21 (2000) 312-315
18. McInnes I.B., Liew F.Y., and Gracie J.A. Interleukin-18: a therapeutic target in rheumatoid arthritis? Arthritis Res. Ther. 7 (2005) 38-41
19. Mogil J.S., Wilson S.G., Bon K., Lee S.E., Chung K., Raber P., Pieper J.O., Hain H.S., Belknap J.K., Hubert L., Elmer G.I., Chung J.M., and Devor M. Heritability of nociception I: responses of 11 inbred mouse strains on 12 measures of nociception. Pain 80 (1999) 67-82
20. Mogil J.S., Wilson S.G., Bon K., Lee S.E., Chung K., Raber P., Pieper J.O., Hain H.S., Belknap J.K., Hubert L., Elmer G.I., Chung J.M., and Devor M. Heritability of nociception II. 'Types' of nociception revealed by genetic correlation analysis. Pain 80 (1999) 83-93
21. Nakanishi K., Yoshimoto T., Tsutsui H., and Okamura H. Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu. Cytokine Growth Factor Rev. 12 (2001) 53-72
22. Netea M.G., Fantuzzi G., Kullberg B.J., Stuyt R.J., Pulido E.J., McIntyre Jr. R.C., Joosten L.A., Van der Meer J.W., and Dinarello C.A. Neutralization of IL-18 reduces neutrophil tissue accumulation and protects mice against lethal Escherichia coli and Salmonella typhimurium endotoxemia. J. Immunol. 164 (2000) 2644-2649
23. Okamura H., Tsutsi H., Komatsu T., Yutsudo M., Hakura A., Tanimoto T., Torigoe K., Okura T., Nukada Y., Hattori K., et al. Cloning of a new cytokine that induces IFN-gamma production by T cells. Nature 378 (1995) 88-91
24. Piovezan A.P., D'Orleans-Juste P., Frighetto M., Souza G.E., Henriques M.G., and Rae G.A. Endothelins contribute towards nociception induced by antigen in ovalbumin-sensitised mice. Br. J. Pharmacol. 141 (2004) 755-763
25. Piovezan A.P., D'Orleans-Juste P., Tonussi C.R., and Rae G.A. Endothelins potentiate formalin-induced nociception and paw edema in mice. Can. J. Physiol. Pharmacol. 75 (1997) 596-600
26. Plater-Zyberk C., Joosten L.A., Helsen M.M., Sattonnet-Roche P., Siegfried C., Alouani S., van De Loo F.A., Graber P., Aloni S., Cirillo R., Lubberts E., Dinarello C.A., van Den Berg W.B., and Chvatchko Y. Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis. J. Clin. Invest. 108 (2001) 1825-1832
27. Raffa R.B., and Jacoby H.I. Endothelin-1, -2 and -3 directly and big-endothelin-1 indirectly elicit an abdominal constriction response in mice. Life Sci. 48 (1991) PL85-PL90
28. Raffa R.B., Schupsky J.J., and Jacoby H.I. Endothelin-induced nociception in mice: mediation by ETA and ETB receptors. J. Pharmacol. Exp. Ther. 276 (1996) 647-651
29. Ribeiro R.A., Vale M.L., Thomazzi S.M., Paschoalato A.B., Poole S., Ferreira S.H., and Cunha F.Q. Involvement of resident macrophages and mast cells in the writhing nociceptive response induced by zymosan and acetic acid in mice. Eur. J. Pharmacol. 387 (2000) 111-118
30. Rothe H., Jenkins N.A., Copeland N.G., and Kolb H. Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2. J. Clin. Invest. 99 (1997) 469-474
31. Valerio D.A., Cunha T.M., Arakawa N.S., Lemos H.P., Da Costa F.B., Parada C.A., Ferreira S.H., Cunha F.Q., and Verri Jr. W.A. Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: inhibition of cytokine production-dependent mechanism. Eur. J. Pharmacol. 562 (2007) 155-163
32. Verri Jr. W.A., Schivo I.R., Cunha T.M., Liew F.Y., Ferreira S.H., and Cunha F.Q. Interleukin-18 induces mechanical hypernociception in rats via endothelin acting on ETB receptors in a morphine-sensitive manner. J. Pharmacol. Exp. Ther. 310 (2004) 710-717
33. Verri Jr. W.A., Molina R.O., Schivo I.R., Cunha T.M., Parada C.A., Poole S., Ferreira S.H., and Cunha F.Q. Nociceptive effect of subcutaneously injected interleukin-12 is mediated by endothelin (ET) acting on ETB receptors in rats. J. Pharmacol. Exp. Ther. 315 (2005) 609-615
34. Verri Jr. W.A., Cunha T.M., Parada C.A., Poole S., Cunha F.Q., and Ferreira S.H. Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development?. Pharmacol. Ther. 112 (2006) 116-138
35. Verri Jr. W.A., Cunha T.M., Parada C.A., Wei X.Q., Ferreira S.H., Liew F.Y., and Cunha F.Q. IL-15 mediates immune inflammatory hypernociception by triggering a sequential release of IFN-γ, endothelin, and prostaglandin. Proc. Natl. Acad. Sci. U.S.A 103 (2006) 9721-9725
36. Verri Jr. W.A., Cunha T.M., Ferreira S.H., Wei X., Leung B.P., Fraser A., McInnes I.B., Liew F.Y., and Cunha F.Q. IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production. Eur. J. Immunol. 37 (2007) 3373-3380
37. Verri Jr. W.A., Cunha T.M., Parada C.A., Poole S., Liew F.Y., Ferreira S.H., and Cunha F.Q. Antigen-induced inflammatory mechanical hypernociception in mice is mediated by IL-18. Brain Behav. Immun. 21 (2007) 535-543
38. Verri Jr. W.A., Guerrero A.T., Fukada S.Y., Valerio D.A., Cunha T.M., Xu D., Ferreira S.H., Liew F.Y., and Cunha F.Q. IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice. Proc. Natl. Acad. Sci. USA 105 (2008) 2723-2728
39. Vivancos G.G., Verri Jr. W.A., Cunha T.M., Schivo I.R., Parada C.A., Cunha F.Q., and Ferreira S.H. An electronic pressure-meter nociception paw test for rats. Braz. J. Med. Biol. Res. 37 (2004) 391-399
40. von Frey M. Untersuchunger über die Sinnesfunctionen der menschlichen Haut. Abhandl. Sachs. Ges. Wiss. 23 (1896) 175-266
41. Wei X.Q., Leung B.P., Arthur H.M., McInnes I.B., and Liew F.Y. Reduced incidence and severity of collagen-induced arthritis in mice lacking IL-18. J. Immunol. 166 (2001) 517-521
42. Wei X.Q., Leung B.P., Niedbala W., Piedrafita D., Feng G.J., Sweet M., Dobbie L., Smith A.J., and Liew F.Y. Altered immune responses and susceptibility to Leishmania major and Staphylococcus aureus infection in IL-18-deficient mice. J. Immunol. 163 (1999) 2821-2828