Hypocretin-1 (orexin A) prevents the effects of hypoxia/hypercapnia and enhances the GABAergic pathway from the lateral paragigantocellular nucleus to cardiac vagal neurons in the nucleus ambiguus

Neuroscience

Volumn 175, Issue , 2011, Pages 18-23

  Dergacheva, O ^a,b   Philbin, K ^a   Bateman, R ^a   Mendelowitz, D ^a  

^a GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b SOUTHERN FEDERAL UNIVERSITY   (Russian Federation)

Author keywords

Bradycardia; Hypocretin; Parasympathetic preganglionic neurons; Rapid eye movement sleep; Rostral ventral medulla

Indexed keywords

1 (2 METHYL 6 BENZOXAZOLYL) 3 (1,5 NAPHTHYRIDIN 4 YL)UREA; OREXIN 1 RECEPTOR; OREXIN A;

AMBIGUUS NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRADYCARDIA; BRAIN HYPOXIA; CONTROLLED STUDY; DOSE RESPONSE; ELECTROSTIMULATION; EXCITATORY POSTSYNAPTIC POTENTIAL; GABAERGIC SYSTEM; GIGANTOCELLULAR RETICULAR NUCLEUS; HEART ARRHYTHMIA; HEART RATE; HYPERCAPNIA; NERVE CONDUCTION; NEUROTRANSMISSION; NONHUMAN; PARASYMPATHETIC NERVE CELL; PATCH CLAMP; PRIORITY JOURNAL; RAT; REM SLEEP; SUDDEN DEATH; VAGUS NERVE;

ANIMALS; ANOXIA; ARRHYTHMIAS, CARDIAC; ELECTRIC STIMULATION; GAMMA-AMINOBUTYRIC ACID; HYPERCAPNIA; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEDULLA OBLONGATA; NEURAL PATHWAYS; NEUROPEPTIDES; ORGAN CULTURE TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; RETICULAR FORMATION; SYNAPTIC POTENTIALS; UP-REGULATION; VAGUS NERVE;

EID: 78951477559     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.11.067     Document Type: Article

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