Millimolar Mn2+ influences agonist binding to 5-HT1A receptors by inhibiting guanosine nucleotide binding to receptor-coupled G-proteins

NeuroToxicology

Volumn 32, Issue 1, 2011, Pages 25-30

  Parkel, Sven ^a   Tõntson, Lauri ^a   Rinken, Ago ^a  

^a UNIVERSITY OF TARTU   (Estonia)

Author keywords

5 HT1A receptor; Cortex; G proteins; Guanosine nucleotides; Hippocampus; Manganese

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MAGNESIUM; MANGANESE; SEROTONIN 1A RECEPTOR; GUANOSINE; SEROTONIN 1 AGONIST;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN CORTEX; CELL MEMBRANE; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; ENZYME ACTIVATION; HIPPOCAMPUS; INTRACELLULAR SIGNALING; LIGAND BINDING; METAL BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RAT; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SYNAPTIC INHIBITION; ANIMAL; ARMYWORM; CELL LINE; CHEMISTRY; COMPARATIVE STUDY; DRUG ANTAGONISM; METABOLISM; PHYSIOLOGY; WISTAR RAT;

RATTUS;

ANIMALS; CELL LINE; GUANOSINE; HIPPOCAMPUS; MANGANESE; PROTEIN BINDING; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTORS, G-PROTEIN-COUPLED; SEROTONIN 5-HT1 RECEPTOR AGONISTS; SPODOPTERA;

EID: 78951469226     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2010.11.005     Document Type: Article

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