Manganese homeostasis in the CNS

Environmental Research

Volumn 80, Issue 2 I, 1999, Pages 105-109

  Aschner, Michael ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE AMMONIA LIGASE; HYDROXYL RADICAL; MANGANESE; OXYGEN RADICAL; SUPEROXIDE DISMUTASE; TRANSFERRIN RECEPTOR;

ACTIVE TRANSPORT; ASTROCYTE; BLOOD BRAIN BARRIER; CAPILLARY ENDOTHELIUM; CENTRAL NERVOUS SYSTEM DISEASE; CEREBROSPINAL FLUID; CHOROID PLEXUS; CONFERENCE PAPER; DENTATE GYRUS; DIFFUSION; HOMEOSTASIS; HUMAN; NONHUMAN; PRIORITY JOURNAL;

EID: 0033047127     PISSN: 00139351     EISSN: None     Source Type: Journal    
DOI: 10.1006/enrs.1998.3918     Document Type: Conference Paper

References (33)

1. Aisen, P., Aisen, R., and Redfield, A. G. (1969). The chronium, manganese, and cobalt complexes of transferrin. J. Boil. Chem. 244, 4628-4633.
2. Aschner, M., and Aschner, J. L. (1990). Manganese transport across the blood-brain barrier: Relationship to iron homeostasis. Brain Res. Bull. 24, 857-860.
3. Aschner, M., and Aschner, J. L. (1991). Manganese neurotoxicity: Cellular effects and blood-brain barrier transport mechanisms. Neurosci. Biobehav. Rev. 15, 333-340.
4. Aschner, M., Gannon, M., Kimelberg, H. K. (1992). Manganese (Mn) uptake and efflux in cultured rat astrocytes. J. Neurochem. 58, 730-735.
5. Aschner, M., and Gannon, M. (1994). Manganese (Mn) transport across the blood-brain barrier: Saturable and transferrin-dependent transport mechanisms. Brain Res. Bull. 33, 345-349.
6. Aschner, M. (1997). Manganese neurotoxicity and oxidative damage. In "Metals and Oxidative Damage in Neurological Disorders" (J. R. Connor, Ed.), pp. 77-93, Plenum Press, New York.
7. Fishman, J. B., Handrahan, J. B., Rubir, J. B., Connor, J. R., and Fine, R. E. (1985). Receptor-mediated trancytosis of transferrin across the blood-brain barrier. J. Cell. Biol. 101, 423A.
8. Gavin, C. E., Gunter, K. K., and Gunter, T. E. (1990). Manganese and calcium efflux kinetics in brain mitochondria: Relevance to manganese toxicity. Biochem. J. 266, 329-334.
9. Hertz, L. (1979). Functional interactions between neurons and astrocytes I. Turnover and metabolism of putative amino acid transmitters. Prog. Neurobiol. 13, 277-323.
10. Hill, J. M., and Switzer, R. C., III (1984). The regional distribution and cellular localization of iron in the rat brain. Neuroscience 11, 595-603.
11. Hill, J. M., Ruff, M. R., and Weber, R. J. (1985). Transferrin receptors in rat brain: Neuropeptide-like pattern and relationship to iron distribution. Proc. Natl. Acad. Sci. USA 82, 4553-4557.
12. Ingersoll, R. T., Montgomery, E. B., Jr., and Aposhian, H. V. (1995). Central nervous system toxicity of manganese. I. Inhibition of spontaneous motor activity in rats after intrathecal administration of manganese chloride. Toxicol. Appl. Pharmacol. 27, 106-113.
13. Jeffries, W. A., Brandon, M. R., Hunt, S. V., Williams, A. F., and Mason, D. Y. (1984). Transferrin receptor on endothelium of brain capillaries. Nature 132, 162-163.
14. Keefer, R. C., Barak, A. J., and Boyett, J. D. (1970). Binding of manganese and transferrin in rat serum. Biochim. Biophys. Acta 221, 390-393.
15. Keen, C. L. (1995). Overview of manganese toxicity. In "Proceedings of the Workshop on the Bioavailability and Oral Toxicity of Manganese" (S. Velazquez, EPA Liaison), pp. 3-11. US EPA, Environmental Criteria and Assessment Office.
16. London, R. E., Toney, G., Gabel, S. A., and Funk, A. (1989). Magnetic resonance imaging studies of the brains of anesthetized rats treated with manganese chloride. Brain Res. Bull. 23, 229-235.
17. Martinez-Hernandez, A., Bell, K. P., and Noremberg, M. D. (1997). Glutamine synthetase: Glial localization in brain. Science 195, 1356-1358.
18. Mena, I., Horiuchi, K., and Lopez, G. (1974). Factors enhancing entrance of manganese into brain: iron deficiency and age. J. Nuclear Med. 15, 516.
19. Morris, C. M., Keith, A. B., Edwardson, J. A., and Pullen, R. G. L. (1992a). Uptake and distribution of iron and transferrin in the adult brain. J. Neurochem. 59, 300-306.
20. Morris, C. M., Candy, J. M., Keith, A. B., Oakley, A., Taylor, G., Pullen, R. G. L., Bloxham, C. A., Gocht, A., and Edwardson, J. A. (1992b). Brain iron homeostasis. J. Inorgan. Biochem. 47, 257-265.
21. Murphy, V. A., Wadhwani, K. C., Smith, Q. R., and Rapoport, S. I. (1991). Saturable transport of manganese (II) across the rat blood-brain barrier. J. Neurochem. 57, 948-954.
22. Partridge, W. M., Eisenberg, J., and Yang, J. (1987). Human blood-brain barrier transferrin receptor. Metabolism 36, 892-895.
23. Rabin, O., Hegedus, L., Bourre, J. M., and Smith Q. R. (1993). Rapid brain uptake of manganese (II) across the blood-brain barrier. J. Neurochem. 61, 509-517.
24. Scheuhammer, A. M., and Cherian, M. G. (1985). Binding of manganese in human and rat plasma. Biochim. Biophys. Acta 840, 163-169.
25. Schramm, V. L., and Brandt, M. (1986). The manganese (II) economy of rat hepatocytes. Fed. Proc. 45, 2817-1820.
26. Sloot, W. N., and Gramsbergen, J. B. (1994). Axonal transport of manganese and its relevance to selective neurotoxicity in the rat basal ganglia. Brain Res. 657, 124-132.
27. Suarez, N., and Eriksson, H. (1993). Receptor-mediated endocytosis of a manganese complex of transferrin into neuroblastoma (SHSY5Y) cells in culture. J. Neurochem. 61, 127-31.
28. Takeda, A., Akiyama, T., Sawashita, J., and Okada, S. (1994). Brain uptake of trace metals, zinc and manganese, in rats. Brain Res. 640, 341-344.
29. Wedler, F. C., Denman, R. B., and Roby, W. G. (1982). Glutamine synthetase from bovine brain in a manganese (II) enzyme. Biochemistry 21, 6389-6396.
30. Wedler, F. C., and Denman, R. B. (1984). Glutamine synthetase: The major Mn (II) enzyme in mammalian brain. Curr. Top. Cell. Regul. 24, 153-169.
31. Wedler, F. C., and Ley, B. W. (1990). Cu(II) and Zn(II) ions alter the dynamics and distribution of Mn(II) in cultured chick glial cells. Neurochem. Res. 15, 1221-1228.
32. Wedler, F. C., Vichnin, M. C., Ley, B. W., Tholey, G., Ledig, M., and Copin, J. C. (1994). Effects of Ca(II) ions on Mn(II) dynamics in chick glia and rat astrocytes: Potential regulation of glutamine synthetase. Neurochem. Res. 19, 145-151.
33. Wedler, F. C., and Ley, B. W. (1994). Kinetic, ESR, and trapping evidence for in vivo binding of Mn(II) to glutamine synthetase in brain cells. Neurochem. Res. 19, 139-144.