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Volumn 1215, Issue 1, 2011, Pages 144-149

Resveratrol in cancer management: Where are we and where we go from here?

Author keywords

Bioavailability; Nanoparticles; Piceatannol; Resveratrol

Indexed keywords

ANDROGEN; CURCUMIN; DRUG METABOLITE; ESTROGEN; GLUCURONIDE; MYRICETIN; NANOCARRIER; PICEATANNOL; PIPERINE; POLYPHENOL; QUERCETIN; RESVERATROL; SULFATE; SULFOTRANSFERASE; URIDINE DIPHOSPHATE GLUCURONIC ACID;

EID: 78851469731     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2010.05851.x     Document Type: Article
Times cited : (81)

References (62)
  • 1
    • 21744443080 scopus 로고    scopus 로고
    • Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease?
    • Aziz, M.H. et al 2005. Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease? FASEB J. 19: 1193-1195.
    • (2005) FASEB J. , vol.19 , pp. 1193-1195
    • Aziz, M.H.1
  • 2
    • 41049114223 scopus 로고    scopus 로고
    • Resveratrol imparts photoprotection of normal cells and enhances the efficacy of radiation therapy in cancer cells
    • Reagan-Shaw, S., H. Mukhtar & N. Ahmad 2008. Resveratrol imparts photoprotection of normal cells and enhances the efficacy of radiation therapy in cancer cells. Photochem. Photobiol. 84: 415-421.
    • (2008) Photochem. Photobiol. , vol.84 , pp. 415-421
    • Reagan-Shaw, S.1    Mukhtar, H.2    Ahmad, N.3
  • 3
    • 0036545884 scopus 로고    scopus 로고
    • Botanical antioxidants for chemoprevention of photocarcinogenesis
    • Afaq, F. et al 2002. Botanical antioxidants for chemoprevention of photocarcinogenesis. Front. Biosci. 7: d784-d792.
    • (2002) Front. Biosci. , vol.7
    • Afaq, F.1
  • 4
    • 34547684362 scopus 로고    scopus 로고
    • Chemoprevention by resveratrol: molecular mechanisms and therapeutic potential
    • Shankar, S., G. Singh & R.K. Srivastava 2007. Chemoprevention by resveratrol: molecular mechanisms and therapeutic potential. Front. Biosci. 12: 4839-4854.
    • (2007) Front. Biosci. , vol.12 , pp. 4839-4854
    • Shankar, S.1    Singh, G.2    Srivastava, R.K.3
  • 5
    • 0036297527 scopus 로고    scopus 로고
    • Cancer chemopreventive activity of resveratrol
    • Bhat, K.P. & J.M. Pezzuto 2002. Cancer chemopreventive activity of resveratrol. Ann. N. Y. Acad. Sci. 957: 210-229.
    • (2002) Ann. N. Y. Acad. Sci. , vol.957 , pp. 210-229
    • Bhat, K.P.1    Pezzuto, J.M.2
  • 6
    • 77956016499 scopus 로고    scopus 로고
    • Cancer prevention with natural compounds
    • Gullett, N.P. et al 2010. Cancer prevention with natural compounds. Semin. Oncol. 37: 258-281.
    • (2010) Semin. Oncol. , vol.37 , pp. 258-281
    • Gullett, N.P.1
  • 7
    • 0346074656 scopus 로고    scopus 로고
    • Cancer chemoprevention by resveratrol: in vitro and in vivo studies and the underlying mechanisms (review)
    • Aziz, M.H., R. Kumar & N. Ahmad 2003. Cancer chemoprevention by resveratrol: in vitro and in vivo studies and the underlying mechanisms (review). Int. J. Oncol. 23: 17-28.
    • (2003) Int. J. Oncol. , vol.23 , pp. 17-28
    • Aziz, M.H.1    Kumar, R.2    Ahmad, N.3
  • 8
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: the in vivo evidence
    • Baur, J.A. & D.A. Sinclair 2006. Therapeutic potential of resveratrol: the in vivo evidence. Nat. Rev. Drug Discov. 5: 493-506.
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 9
    • 0026651085 scopus 로고
    • Wine, alcohol, platelets, and the French paradox for coronary heart disease
    • Renaud, S. & M. de Lorgeril 1992. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet 339: 1523-1526.
    • (1992) Lancet , vol.339 , pp. 1523-1526
    • Renaud, S.1    de Lorgeril, M.2
  • 10
    • 78651141309 scopus 로고
    • [Chemical Constituents of Polygonaceous Plants. I. Studies on the Components of Ko-J O-Kon. (Polygonum Cuspidatum Sieb. Et Zucc.)]
    • Nonomura, S., H. Kanagawa & A. Makimoto 1963. [Chemical Constituents of Polygonaceous Plants. I. Studies on the Components of Ko-J O-Kon. (Polygonum Cuspidatum Sieb. Et Zucc.)]. Yakugaku Zasshi. 83: 988-990.
    • (1963) Yakugaku Zasshi. , vol.83 , pp. 988-990
    • Nonomura, S.1    Kanagawa, H.2    Makimoto, A.3
  • 11
    • 0345566753 scopus 로고    scopus 로고
    • Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells
    • Clement, M.V. et al 1998. Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells. Blood 92: 996-1002.
    • (1998) Blood , vol.92 , pp. 996-1002
    • Clement, M.V.1
  • 12
    • 0031561513 scopus 로고    scopus 로고
    • Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
    • Jang, M. et al 1997. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 275: 218-220.
    • (1997) Science , vol.275 , pp. 218-220
    • Jang, M.1
  • 13
    • 14744268831 scopus 로고    scopus 로고
    • Prevention of ultraviolet-B radiation damage by resveratrol in mouse skin is mediated via modulation in surviving
    • Aziz, M.H., F. Afaq & N. Ahmad 2005. Prevention of ultraviolet-B radiation damage by resveratrol in mouse skin is mediated via modulation in surviving. Photochem. Photobiol. 81: 25-31.
    • (2005) Photochem. Photobiol. , vol.81 , pp. 25-31
    • Aziz, M.H.1    Afaq, F.2    Ahmad, N.3
  • 14
    • 33745089904 scopus 로고    scopus 로고
    • Resveratrol-caused apoptosis of human prostate carcinoma LNCaP cells is mediated via modulation of phosphatidylinositol 3'-kinase/Akt pathway and Bcl-2 family proteins
    • Aziz, M.H. et al 2006. Resveratrol-caused apoptosis of human prostate carcinoma LNCaP cells is mediated via modulation of phosphatidylinositol 3'-kinase/Akt pathway and Bcl-2 family proteins. Mol. Cancer Ther. 5: 1335-1341.
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 1335-1341
    • Aziz, M.H.1
  • 15
    • 3142678185 scopus 로고    scopus 로고
    • Modulations of critical cell cycle regulatory events during chemoprevention of ultraviolet B-mediated responses by resveratrol in SKH-1 hairless mouse skin
    • Reagan-Shaw, S. et al 2004. Modulations of critical cell cycle regulatory events during chemoprevention of ultraviolet B-mediated responses by resveratrol in SKH-1 hairless mouse skin. Oncogene 23: 5151-5160.
    • (2004) Oncogene , vol.23 , pp. 5151-5160
    • Reagan-Shaw, S.1
  • 16
    • 67650297506 scopus 로고    scopus 로고
    • Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials
    • Bishayee, A. 2009. Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials. Cancer Prev. Res. (Phila Pa). 2: 409-418.
    • (2009) Cancer Prev. Res. (Phila Pa). , vol.2 , pp. 409-418
    • Bishayee, A.1
  • 17
    • 0037288709 scopus 로고    scopus 로고
    • Prevention of short-term ultraviolet B radiation-mediated damages by resveratrol in SKH-1 hairless mice
    • Afaq, F., V.M. Adhami & N. Ahmad 2003. Prevention of short-term ultraviolet B radiation-mediated damages by resveratrol in SKH-1 hairless mice. Toxicol. Appl. Pharmacol. 186: 28-37.
    • (2003) Toxicol. Appl. Pharmacol. , vol.186 , pp. 28-37
    • Afaq, F.1    Adhami, V.M.2    Ahmad, N.3
  • 18
    • 1242293646 scopus 로고    scopus 로고
    • Resveratrol inhibits drug-induced apoptosis in human leukemia cells by creating an intracellular milieu nonpermissive for death execution
    • Ahmad, K.A. et al 2004. Resveratrol inhibits drug-induced apoptosis in human leukemia cells by creating an intracellular milieu nonpermissive for death execution. Cancer Res. 64: 1452-1459.
    • (2004) Cancer Res. , vol.64 , pp. 1452-1459
    • Ahmad, K.A.1
  • 19
    • 34147111846 scopus 로고    scopus 로고
    • Protein kinase CK2 modulates apoptosis induced by resveratrol and epigallocatechin-3-gallate in prostate cancer cells
    • Ahmad, K.A. et al 2007. Protein kinase CK2 modulates apoptosis induced by resveratrol and epigallocatechin-3-gallate in prostate cancer cells. Mol. Cancer Ther. 6: 1006-1012.
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 1006-1012
    • Ahmad, K.A.1
  • 20
    • 0037295102 scopus 로고    scopus 로고
    • Molecular mechanism of the chemopreventive effect of resveratrol
    • Dong, Z. 2003. Molecular mechanism of the chemopreventive effect of resveratrol. Mutat. Res. 523-524: 145-150.
    • (2003) Mutat. Res. , vol.523-524 , pp. 145-150
    • Dong, Z.1
  • 21
    • 38649132291 scopus 로고    scopus 로고
    • Resveratrol and its analogs: defense against cancer, coronary disease and neurodegenerative maladies or just a fad?
    • Saiko, P. et al 2008. Resveratrol and its analogs: defense against cancer, coronary disease and neurodegenerative maladies or just a fad? Mutat. Res. 658: 68-94.
    • (2008) Mutat. Res. , vol.658 , pp. 68-94
    • Saiko, P.1
  • 22
    • 34250901592 scopus 로고    scopus 로고
    • Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemopreventive agent
    • Boocock, D.J. et al 2007. Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemopreventive agent. Cancer Epidemiol. Biomarkers Prev. 16: 1246-1252.
    • (2007) Cancer Epidemiol. Biomarkers Prev. , vol.16 , pp. 1246-1252
    • Boocock, D.J.1
  • 23
    • 9444296057 scopus 로고    scopus 로고
    • High absorption but very low bioavailability of oral resveratrol in humans
    • Walle, T. et al 2004. High absorption but very low bioavailability of oral resveratrol in humans. Drug Metab. Dispos. 32: 1377-1382.
    • (2004) Drug Metab. Dispos. , vol.32 , pp. 1377-1382
    • Walle, T.1
  • 24
    • 20344364428 scopus 로고    scopus 로고
    • Metabolism and bioavailability of trans-resveratrol
    • Wenzel, E. & V. Somoza 2005. Metabolism and bioavailability of trans-resveratrol. Mol. Nutr. Food Res. 49: 472-481.
    • (2005) Mol. Nutr. Food Res. , vol.49 , pp. 472-481
    • Wenzel, E.1    Somoza, V.2
  • 25
    • 48649106985 scopus 로고    scopus 로고
    • Quantification of free and protein-bound trans-resveratrol metabolites and identification of trans-resveratrol-C/O-conjugated diglucuronides - two novel resveratrol metabolites in human plasma
    • Burkon, A. & V. Somoza 2008. Quantification of free and protein-bound trans-resveratrol metabolites and identification of trans-resveratrol-C/O-conjugated diglucuronides - two novel resveratrol metabolites in human plasma. Mol. Nutr. Food Res. 52: 549-557.
    • (2008) Mol. Nutr. Food Res. , vol.52 , pp. 549-557
    • Burkon, A.1    Somoza, V.2
  • 26
    • 67649999248 scopus 로고    scopus 로고
    • Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers
    • Almeida, L. et al 2009. Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers. Mol. Nutr. Food Res. 53(Suppl 1): S7-S15.
    • (2009) Mol. Nutr. Food Res. , vol.53 , Issue.SUPPL. 1
    • Almeida, L.1
  • 27
    • 71449113221 scopus 로고    scopus 로고
    • Pharmacokinetics of trans-resveratrol following repeated administration in healthy elderly and young subjects
    • Nunes, T. et al 2009. Pharmacokinetics of trans-resveratrol following repeated administration in healthy elderly and young subjects. J. Clin. Pharmacol. 49: 1477-1482.
    • (2009) J. Clin. Pharmacol. , vol.49 , pp. 1477-1482
    • Nunes, T.1
  • 28
    • 56749153720 scopus 로고    scopus 로고
    • Effect of food on the pharmacokinetic profile of trans-resveratrol
    • Vaz-da-Silva, M. et al 2008. Effect of food on the pharmacokinetic profile of trans-resveratrol. Int. J. Clin. Pharmacol. Ther. 46: 564-570.
    • (2008) Int. J. Clin. Pharmacol. Ther. , vol.46 , pp. 564-570
    • Vaz-da-Silva, M.1
  • 29
    • 74349100733 scopus 로고    scopus 로고
    • Resveratrol bioavailability and toxicity in humans
    • Cottart, C.H. et al 2010. Resveratrol bioavailability and toxicity in humans. Mol. Nutr. Food Res. 54: 7-16.
    • (2010) Mol. Nutr. Food Res. , vol.54 , pp. 7-16
    • Cottart, C.H.1
  • 30
    • 77957355158 scopus 로고    scopus 로고
    • Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients
    • Patel, K.R. et al 2010. Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients. Cancer Res. 70: 7392-7399.
    • (2010) Cancer Res. , vol.70 , pp. 7392-7399
    • Patel, K.R.1
  • 31
    • 78549288940 scopus 로고    scopus 로고
    • Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: safety, pharmacokinetics and effect on the insulin-like growth factor axis
    • Advance online publication. doi:.
    • Brown, V.A. et al 2010. Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: safety, pharmacokinetics and effect on the insulin-like growth factor axis. Cancer Res. Advance online publication. doi:.
    • (2010) Cancer Res.
    • Brown, V.A.1
  • 32
    • 0027249976 scopus 로고
    • Impairment of UDP-glucose dehydrogenase and glucuronidation activities in liver and small intestine of rat and guinea pig in vitro by piperine
    • Reen, R.K. et al 1993. Impairment of UDP-glucose dehydrogenase and glucuronidation activities in liver and small intestine of rat and guinea pig in vitro by piperine. Biochem. Pharmacol. 46: 229-238.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 229-238
    • Reen, R.K.1
  • 33
    • 0021931513 scopus 로고
    • Biochemical basis of enhanced drug bioavailability by piperine: evidence that piperine is a potent inhibitor of drug metabolism
    • Atal, C.K., R.K. Dubey & J. Singh 1985. Biochemical basis of enhanced drug bioavailability by piperine: evidence that piperine is a potent inhibitor of drug metabolism. J. Pharmacol. Exp. Ther. 232: 258-262.
    • (1985) J. Pharmacol. Exp. Ther. , vol.232 , pp. 258-262
    • Atal, C.K.1    Dubey, R.K.2    Singh, J.3
  • 34
    • 35948951161 scopus 로고    scopus 로고
    • Black pepper and its pungent principle-piperine: a review of diverse physiological effects
    • Srinivasan, K. 2007. Black pepper and its pungent principle-piperine: a review of diverse physiological effects. Crit. Rev. Food. Sci. Nutr. 47: 735-748.
    • (2007) Crit. Rev. Food. Sci. Nutr. , vol.47 , pp. 735-748
    • Srinivasan, K.1
  • 35
    • 3543088026 scopus 로고    scopus 로고
    • Piperine enhances the bioavailability of the tea polyphenol (-)-epigallocatechin-3-gallate in mice
    • Lambert, J.D. et al 2004. Piperine enhances the bioavailability of the tea polyphenol (-)-epigallocatechin-3-gallate in mice. J. Nutr. 134: 1948-1952.
    • (2004) J. Nutr. , vol.134 , pp. 1948-1952
    • Lambert, J.D.1
  • 36
    • 0034491047 scopus 로고    scopus 로고
    • Glucuronidation of resveratrol, a natural product present in grape and wine, in the human liver
    • de Santi, C. et al 2000. Glucuronidation of resveratrol, a natural product present in grape and wine, in the human liver. Xenobiotica 30: 1047-1054.
    • (2000) Xenobiotica , vol.30 , pp. 1047-1054
    • de Santi, C.1
  • 37
    • 0033777342 scopus 로고    scopus 로고
    • Sulphation of resveratrol, a natural compound present in wine, and its inhibition by natural flavonoids
    • De Santi, C. et al 2000. Sulphation of resveratrol, a natural compound present in wine, and its inhibition by natural flavonoids. Xenobiotica 30: 857-866.
    • (2000) Xenobiotica , vol.30 , pp. 857-866
    • De Santi, C.1
  • 38
    • 0033937909 scopus 로고    scopus 로고
    • Sulphation of resveratrol, a natural product present in grapes and wine, in the human liver and duodenum
    • De Santi, C. et al 2000. Sulphation of resveratrol, a natural product present in grapes and wine, in the human liver and duodenum. Xenobiotica 30: 609-617.
    • (2000) Xenobiotica , vol.30 , pp. 609-617
    • De Santi, C.1
  • 39
    • 77949541883 scopus 로고    scopus 로고
    • Antioxidant effect of trans-resveratrol, pterostilbene, quercetin and their combinations in human erythrocytes in vitro
    • Mikstacka, R., A.M. Rimando & E. Ignatowicz 2010. Antioxidant effect of trans-resveratrol, pterostilbene, quercetin and their combinations in human erythrocytes in vitro. Plant. Foods Hum. Nutr. 65: 57-63.
    • (2010) Plant. Foods Hum. Nutr. , vol.65 , pp. 57-63
    • Mikstacka, R.1    Rimando, A.M.2    Ignatowicz, E.3
  • 40
    • 77953353711 scopus 로고    scopus 로고
    • Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects
    • la Porte, C. et al 2010. Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects. Clin. Pharmacokinet. 49: 449-454.
    • (2010) Clin. Pharmacokinet. , vol.49 , pp. 449-454
    • la Porte, C.1
  • 41
    • 77958019137 scopus 로고    scopus 로고
    • Nanochemoprevention: sustained release of bioactive food components for cancer prevention
    • Siddiqui, I.A. et al 2010. Nanochemoprevention: sustained release of bioactive food components for cancer prevention. Nutr. Cancer. 62: 883-890.
    • (2010) Nutr. Cancer. , vol.62 , pp. 883-890
    • Siddiqui, I.A.1
  • 42
    • 67349274374 scopus 로고    scopus 로고
    • Resveratrol-loaded polymeric micelles protect cells from Abeta-induced oxidative stress
    • Lu, X. et al 2009. Resveratrol-loaded polymeric micelles protect cells from Abeta-induced oxidative stress. Int. J. Pharm. 375: 89-96.
    • (2009) Int. J. Pharm. , vol.375 , pp. 89-96
    • Lu, X.1
  • 43
    • 67349197868 scopus 로고    scopus 로고
    • Enhanced growth inhibition effect of resveratrol incorporated into biodegradable nanoparticles against glioma cells is mediated by the induction of intracellular reactive oxygen species levels
    • Shao, J. et al 2009. Enhanced growth inhibition effect of resveratrol incorporated into biodegradable nanoparticles against glioma cells is mediated by the induction of intracellular reactive oxygen species levels. Colloids Surf. B. Biointerfaces 72: 40-47.
    • (2009) Colloids Surf. B. Biointerfaces , vol.72 , pp. 40-47
    • Shao, J.1
  • 44
    • 77951256976 scopus 로고    scopus 로고
    • The evidence for solid lipid nanoparticles mediated cell uptake of resveratrol
    • Teskac, K. & J. Kristl 2010. The evidence for solid lipid nanoparticles mediated cell uptake of resveratrol. Int. J. Pharm. 390: 61-69.
    • (2010) Int. J. Pharm. , vol.390 , pp. 61-69
    • Teskac, K.1    Kristl, J.2
  • 45
    • 77956156498 scopus 로고    scopus 로고
    • Anticancer activity and molecular mechanism of resveratrol-bovine serum albumin nanoparticles on subcutaneously implanted human primary ovarian carcinoma cells in nude mice
    • Guo, L. et al 2010. Anticancer activity and molecular mechanism of resveratrol-bovine serum albumin nanoparticles on subcutaneously implanted human primary ovarian carcinoma cells in nude mice. Cancer Biother. Radiopharm. 25: 471-477.
    • (2010) Cancer Biother. Radiopharm. , vol.25 , pp. 471-477
    • Guo, L.1
  • 46
    • 66149107051 scopus 로고    scopus 로고
    • Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice
    • Narayanan, N.K. et al 2009. Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice. Int. J. Cancer. 125: 1-8.
    • (2009) Int. J. Cancer. , vol.125 , pp. 1-8
    • Narayanan, N.K.1
  • 47
    • 77953230986 scopus 로고    scopus 로고
    • Resveratrol and resveratrol analogues-structure-activity relationship
    • Szekeres, T. et al 2010. Resveratrol and resveratrol analogues-structure-activity relationship. Pharm. Res. 27: 1042-1048.
    • (2010) Pharm. Res. , vol.27 , pp. 1042-1048
    • Szekeres, T.1
  • 48
    • 0021276662 scopus 로고
    • Use of potato disc and brine shrimp bioassays to detect activity and isolate piceatannol as the antileukemic principle from the seeds of Euphorbia lagascae
    • Ferrigni, N.R. et al 1984. Use of potato disc and brine shrimp bioassays to detect activity and isolate piceatannol as the antileukemic principle from the seeds of Euphorbia lagascae. J. Nat. Prod. 47: 347-352.
    • (1984) J. Nat. Prod. , vol.47 , pp. 347-352
    • Ferrigni, N.R.1
  • 49
    • 18344372908 scopus 로고    scopus 로고
    • The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1
    • Potter, G.A. et al 2002. The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1. Br. J. Cancer 86: 774-778.
    • (2002) Br. J. Cancer , vol.86 , pp. 774-778
    • Potter, G.A.1
  • 50
    • 70350507937 scopus 로고    scopus 로고
    • The grape component piceatannol induces apoptosis in DU145 human prostate cancer cells via the activation of extrinsic and intrinsic pathways
    • Kim, E.J. et al 2009. The grape component piceatannol induces apoptosis in DU145 human prostate cancer cells via the activation of extrinsic and intrinsic pathways. J. Med. Food 12: 943-951.
    • (2009) J. Med. Food , vol.12 , pp. 943-951
    • Kim, E.J.1
  • 51
    • 70349970798 scopus 로고    scopus 로고
    • Piceatannol, a natural stilbene from grapes, induces G1 cell cycle arrest in androgen-insensitive DU145 human prostate cancer cells via the inhibition of CDK activity
    • Lee, Y.M. et al 2009. Piceatannol, a natural stilbene from grapes, induces G1 cell cycle arrest in androgen-insensitive DU145 human prostate cancer cells via the inhibition of CDK activity. Cancer Lett. 285: 166-173.
    • (2009) Cancer Lett. , vol.285 , pp. 166-173
    • Lee, Y.M.1
  • 52
    • 77955795005 scopus 로고    scopus 로고
    • Pro- and anti-carcinogenic mechanisms of piceatannol are activated dose-dependently in MCF-7 breast cancer cells
    • Advance online publication. doi:.
    • Vo, T.P. et al 2009. Pro- and anti-carcinogenic mechanisms of piceatannol are activated dose-dependently in MCF-7 breast cancer cells. Carcinogenesis. Advance online publication. doi:.
    • (2009) Carcinogenesis
    • Vo, T.P.1
  • 53
    • 48649110627 scopus 로고    scopus 로고
    • The grape and wine constituent piceatannol inhibits proliferation of human bladder cancer cells via blocking cell cycle progression and inducing Fas/membrane bound Fas ligand-mediated apoptotic pathway
    • Kuo, P.L. & Y.L. Hsu 2008. The grape and wine constituent piceatannol inhibits proliferation of human bladder cancer cells via blocking cell cycle progression and inducing Fas/membrane bound Fas ligand-mediated apoptotic pathway. Mol. Nutr. Food Res. 52: 408-418.
    • (2008) Mol. Nutr. Food Res. , vol.52 , pp. 408-418
    • Kuo, P.L.1    Hsu, Y.L.2
  • 54
    • 77955373319 scopus 로고    scopus 로고
    • Piceatannol, a catechol-type polyphenol, inhibits phorbol ester-induced NF-{kappa}B activation and cyclooxygenase-2 expression in human breast epithelial cells: cysteine 179 of IKK{beta} as a potential target
    • Son, P.S. et al 2010. Piceatannol, a catechol-type polyphenol, inhibits phorbol ester-induced NF-{kappa}B activation and cyclooxygenase-2 expression in human breast epithelial cells: cysteine 179 of IKK{beta} as a potential target. Carcinogenesis 31: 1442-1449.
    • (2010) Carcinogenesis , vol.31 , pp. 1442-1449
    • Son, P.S.1
  • 55
    • 70350128241 scopus 로고    scopus 로고
    • Cytotoxic, cytoprotective and antioxidant activities of resveratrol and analogues in C6 astroglioma cells in vitro
    • Ruweler, M. et al 2009. Cytotoxic, cytoprotective and antioxidant activities of resveratrol and analogues in C6 astroglioma cells in vitro. Chem. Biol. Interact. 182: 128-135.
    • (2009) Chem. Biol. Interact. , vol.182 , pp. 128-135
    • Ruweler, M.1
  • 56
    • 35348971413 scopus 로고    scopus 로고
    • Novel resveratrol derivatives induce apoptosis and cause cell cycle arrest in prostate cancer cell lines
    • Horvath, Z. et al 2007. Novel resveratrol derivatives induce apoptosis and cause cell cycle arrest in prostate cancer cell lines. Anticancer Res. 27: 3459-3464.
    • (2007) Anticancer Res. , vol.27 , pp. 3459-3464
    • Horvath, Z.1
  • 57
    • 38449115124 scopus 로고    scopus 로고
    • N-hydroxy-N'-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxy-benzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: synergistic antitumor activity with arabinofuranosylcytosine
    • Saiko, P. et al 2007. N-hydroxy-N'-(3, 4, 5-trimethoxyphenyl)-3, 4, 5-trimethoxy-benzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: synergistic antitumor activity with arabinofuranosylcytosine. Int. J. Oncol. 31: 1261-1266.
    • (2007) Int. J. Oncol. , vol.31 , pp. 1261-1266
    • Saiko, P.1
  • 58
    • 77955324216 scopus 로고    scopus 로고
    • Design, synthesis, and biological evaluation of resveratrol analogues as aromatase and quinone reductase 2 inhibitors for chemoprevention of cancer
    • Sun, B. et al 2010. Design, synthesis, and biological evaluation of resveratrol analogues as aromatase and quinone reductase 2 inhibitors for chemoprevention of cancer. Bioorg. Med. Chem. 18: 5352-5366.
    • (2010) Bioorg. Med. Chem. , vol.18 , pp. 5352-5366
    • Sun, B.1
  • 59
    • 77956338448 scopus 로고    scopus 로고
    • Synthesis of heterocycle-based analogs of resveratrol and their antitumor and vasorelaxing properties
    • Bertini, S. et al 2010. Synthesis of heterocycle-based analogs of resveratrol and their antitumor and vasorelaxing properties. Bioorg. Med. Chem. 18: 6715-6724.
    • (2010) Bioorg. Med. Chem. , vol.18 , pp. 6715-6724
    • Bertini, S.1
  • 60
    • 71949109410 scopus 로고    scopus 로고
    • Soluble polyphenols: synthesis and bioavailability of 3,4',5-tri(alpha-D-glucose-3-O-succinyl) resveratrol
    • Biasutto, L. et al 2009. Soluble polyphenols: synthesis and bioavailability of 3, 4', 5-tri(alpha-D-glucose-3-O-succinyl) resveratrol. Bioorg. Med. Chem. Lett. 19: 6721-6724.
    • (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 6721-6724
    • Biasutto, L.1
  • 61
    • 40449086665 scopus 로고    scopus 로고
    • Dose translation from animal to human studies revisited
    • Reagan-Shaw, S., M. Nihal & N. Ahmad 2008. Dose translation from animal to human studies revisited. FASEB J. 22: 659-661.
    • (2008) FASEB J. , vol.22 , pp. 659-661
    • Reagan-Shaw, S.1    Nihal, M.2    Ahmad, N.3
  • 62
    • 77954331919 scopus 로고    scopus 로고
    • Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites
    • Hoshino, J. et al 2010. Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites. J. Med. Chem. 53: 5033-5043.
    • (2010) J. Med. Chem. , vol.53 , pp. 5033-5043
    • Hoshino, J.1


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