-
1
-
-
44649117905
-
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells.
-
10.1016/j.cell.2008.04.043, 18555785
-
Chen X, Xu H, Yuan P, Fang F, Huss M, Vega VB, Wong E, Orlov YL, Zhang W, Jiang J, Loh YH, Yeo HC, Yeo ZX, Narang V, Govindarajan KR, Leong B, Shahab A, Ruan Y, Bourque G, Sung WK, Clarke ND, Wei CL, Ng HH. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 2008, 133:1106-1117. 10.1016/j.cell.2008.04.043, 18555785.
-
(2008)
Cell
, vol.133
, pp. 1106-1117
-
-
Chen, X.1
Xu, H.2
Yuan, P.3
Fang, F.4
Huss, M.5
Vega, V.B.6
Wong, E.7
Orlov, Y.L.8
Zhang, W.9
Jiang, J.10
Loh, Y.H.11
Yeo, H.C.12
Yeo, Z.X.13
Narang, V.14
Govindarajan, K.R.15
Leong, B.16
Shahab, A.17
Ruan, Y.18
Bourque, G.19
Sung, W.K.20
Clarke, N.D.21
Wei, C.L.22
Ng, H.H.23
more..
-
2
-
-
57349113761
-
Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen.
-
10.1038/nature07483, 2920208, 19005469
-
Hurtado A, Holmes KA, Geistlinger TR, Hutcheson IR, Nicholson RI, Brown M, Jiang J, Howat WJ, Ali S, Carroll JS. Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen. Nature 2008, 456:663-666. 10.1038/nature07483, 2920208, 19005469.
-
(2008)
Nature
, vol.456
, pp. 663-666
-
-
Hurtado, A.1
Holmes, K.A.2
Geistlinger, T.R.3
Hutcheson, I.R.4
Nicholson, R.I.5
Brown, M.6
Jiang, J.7
Howat, W.J.8
Ali, S.9
Carroll, J.S.10
-
3
-
-
68949213578
-
Insights from genomic profiling of transcription factors.
-
10.1038/nrg2636, 2846386, 19668247
-
Farnham PJ. Insights from genomic profiling of transcription factors. Nat Rev Genet 2009, 10:605-616. 10.1038/nrg2636, 2846386, 19668247.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 605-616
-
-
Farnham, P.J.1
-
4
-
-
18344369543
-
MicroRNA biogenesis: coordinated cropping and dicing.
-
10.1038/nrm1644, 15852042
-
Kim VN. MicroRNA biogenesis: coordinated cropping and dicing. Nat Rev Mol Cell Biol 2005, 6:376-385. 10.1038/nrm1644, 15852042.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 376-385
-
-
Kim, V.N.1
-
5
-
-
62249133709
-
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals.
-
10.1038/nature07672, 2754849, 19182780
-
Guttman M, Amit I, Garber M, French C, Lin MF, Feldser D, Huarte M, Zuk O, Carey BW, Cassady JP, Cabili MN, Jaenisch R, Mikkelsen TS, Jacks T, Hacohen N, Bernstein BE, Kellis M, Regev A, Rinn JL, Lander ES. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature 2009, 458:223-227. 10.1038/nature07672, 2754849, 19182780.
-
(2009)
Nature
, vol.458
, pp. 223-227
-
-
Guttman, M.1
Amit, I.2
Garber, M.3
French, C.4
Lin, M.F.5
Feldser, D.6
Huarte, M.7
Zuk, O.8
Carey, B.W.9
Cassady, J.P.10
Cabili, M.N.11
Jaenisch, R.12
Mikkelsen, T.S.13
Jacks, T.14
Hacohen, N.15
Bernstein, B.E.16
Kellis, M.17
Regev, A.18
Rinn, J.L.19
Lander, E.S.20
more..
-
6
-
-
33847038668
-
MicroRNAs play an essential role in the development of cardiac hypertrophy.
-
10.1161/01.RES.0000257913.42552.23, 17234972
-
Sayed D, Hong C, Chen IY, Lypowy J, Abdellatif M. MicroRNAs play an essential role in the development of cardiac hypertrophy. Circ Res 2007, 100:416-424. 10.1161/01.RES.0000257913.42552.23, 17234972.
-
(2007)
Circ Res
, vol.100
, pp. 416-424
-
-
Sayed, D.1
Hong, C.2
Chen, I.Y.3
Lypowy, J.4
Abdellatif, M.5
-
7
-
-
34547579291
-
MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure.
-
10.1161/CIRCULATIONAHA.107.687947, 17606841
-
Thum T, Galuppo P, Wolf C, Fiedler J, Kneitz S, van Laake LW, Doevendans PA, Mummery CL, Borlak J, Haverich A, Gross C, Engelhardt S, Ertl G, Bauersachs J. MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure. Circulation 2007, 116:258-267. 10.1161/CIRCULATIONAHA.107.687947, 17606841.
-
(2007)
Circulation
, vol.116
, pp. 258-267
-
-
Thum, T.1
Galuppo, P.2
Wolf, C.3
Fiedler, J.4
Kneitz, S.5
van Laake, L.W.6
Doevendans, P.A.7
Mummery, C.L.8
Borlak, J.9
Haverich, A.10
Gross, C.11
Engelhardt, S.12
Ertl, G.13
Bauersachs, J.14
-
8
-
-
33845317603
-
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure.
-
10.1073/pnas.0608791103, 1838739, 17108080
-
van Rooij E, Sutherland LB, Liu N, Williams AH, McAnally J, Gerard RD, Richardson JA, Olson EN. A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc Natl Acad Sci USA 2006, 103:18255-18260. 10.1073/pnas.0608791103, 1838739, 17108080.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18255-18260
-
-
van Rooij, E.1
Sutherland, L.B.2
Liu, N.3
Williams, A.H.4
McAnally, J.5
Gerard, R.D.6
Richardson, J.A.7
Olson, E.N.8
-
9
-
-
41149117385
-
MicroRNAs flex their muscles.
-
10.1016/j.tig.2008.01.007, 18325627
-
van Rooij E, Liu N, Olson EN. MicroRNAs flex their muscles. Trends Genet 2008, 24:159-166. 10.1016/j.tig.2008.01.007, 18325627.
-
(2008)
Trends Genet
, vol.24
, pp. 159-166
-
-
van Rooij, E.1
Liu, N.2
Olson, E.N.3
-
10
-
-
34247158646
-
Ubiquitination and degradation of the anti-apoptotic protein ARC by MDM2.
-
10.1074/jbc.M609046200, 17142834
-
Foo RS, Chan LK, Kitsis RN, Bennett MR. Ubiquitination and degradation of the anti-apoptotic protein ARC by MDM2. J Biol Chem 2007, 282:5529-5535. 10.1074/jbc.M609046200, 17142834.
-
(2007)
J Biol Chem
, vol.282
, pp. 5529-5535
-
-
Foo, R.S.1
Chan, L.K.2
Kitsis, R.N.3
Bennett, M.R.4
-
11
-
-
33947520124
-
P53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload.
-
10.1038/nature05602, 17334357
-
Sano M, Minamino T, Toko H, Miyauchi H, Orimo M, Qin Y, Akazawa H, Tateno K, Kayama Y, Harada M, Shimizu I, Asahara T, Hamada H, Tomita S, Molkentin JD, Zou Y, Komuro I. p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload. Nature 2007, 446:444-448. 10.1038/nature05602, 17334357.
-
(2007)
Nature
, vol.446
, pp. 444-448
-
-
Sano, M.1
Minamino, T.2
Toko, H.3
Miyauchi, H.4
Orimo, M.5
Qin, Y.6
Akazawa, H.7
Tateno, K.8
Kayama, Y.9
Harada, M.10
Shimizu, I.11
Asahara, T.12
Hamada, H.13
Tomita, S.14
Molkentin, J.D.15
Zou, Y.16
Komuro, I.17
-
12
-
-
35748961986
-
P53 enters the microRNA world.
-
10.1016/j.ccr.2007.10.028, 17996645
-
Hermeking H. p53 enters the microRNA world. Cancer Cell 2007, 12:414-418. 10.1016/j.ccr.2007.10.028, 17996645.
-
(2007)
Cancer Cell
, vol.12
, pp. 414-418
-
-
Hermeking, H.1
-
13
-
-
33748284288
-
Heme oxygenase-1 gene transfer inhibits angiotensin II-mediated rat cardiac myocyte apoptosis but not hypertrophy.
-
10.1002/jcp.20723, 16826603
-
Foo RS, Siow RC, Brown MJ, Bennett MR. Heme oxygenase-1 gene transfer inhibits angiotensin II-mediated rat cardiac myocyte apoptosis but not hypertrophy. J Cell Physiol 2006, 209:1-7. 10.1002/jcp.20723, 16826603.
-
(2006)
J Cell Physiol
, vol.209
, pp. 1-7
-
-
Foo, R.S.1
Siow, R.C.2
Brown, M.J.3
Bennett, M.R.4
-
14
-
-
0033848608
-
Functional evidence for a cyclic-AMP related mechanism of action of the beta(2)-adrenoceptor in human ventricular myocytes.
-
10.1006/jmcc.2000.1171, 10860775
-
Adamson DL, Money-Kyrle AR, Harding SE. Functional evidence for a cyclic-AMP related mechanism of action of the beta(2)-adrenoceptor in human ventricular myocytes. J Mol Cell Cardiol 2000, 32:1353-1360. 10.1006/jmcc.2000.1171, 10860775.
-
(2000)
J Mol Cell Cardiol
, vol.32
, pp. 1353-1360
-
-
Adamson, D.L.1
Money-Kyrle, A.R.2
Harding, S.E.3
-
15
-
-
33748469506
-
Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis.
-
10.1038/nm1459, 16892061
-
Clarke MC, Figg N, Maguire JJ, Davenport AP, Goddard M, Littlewood TD, Bennett MR. Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis. Nat Med 2006, 12:1075-1080. 10.1038/nm1459, 16892061.
-
(2006)
Nat Med
, vol.12
, pp. 1075-1080
-
-
Clarke, M.C.1
Figg, N.2
Maguire, J.J.3
Davenport, A.P.4
Goddard, M.5
Littlewood, T.D.6
Bennett, M.R.7
-
16
-
-
53849146020
-
Model-based analysis of ChIP-Seq (MACS).
-
10.1186/gb-2008-9-9-r137, 2592715, 18798982
-
Zhang Y, Liu T, Meyer CA, Eeckhoute J, Johnson DS, Bernstein BE, Nussbaum C, Myers RM, Brown M, Li W, Liu XS. Model-based analysis of ChIP-Seq (MACS). Genome Biol 2008, 9:R137. 10.1186/gb-2008-9-9-r137, 2592715, 18798982.
-
(2008)
Genome Biol
, vol.9
-
-
Zhang, Y.1
Liu, T.2
Meyer, C.A.3
Eeckhoute, J.4
Johnson, D.S.5
Bernstein, B.E.6
Nussbaum, C.7
Myers, R.M.8
Brown, M.9
Li, W.10
Liu, X.S.11
-
17
-
-
33747836850
-
CEAS: cis-regulatory element annotation system.
-
10.1093/nar/gkl322, 1538818, 16845068
-
Ji X, Li W, Song J, Wei L, Liu XS. CEAS: cis-regulatory element annotation system. Nucleic Acids Res 2006, 34:W551-554. 10.1093/nar/gkl322, 1538818, 16845068.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Ji, X.1
Li, W.2
Song, J.3
Wei, L.4
Liu, X.S.5
-
18
-
-
67849122320
-
MEME SUITE: tools for motif discovery and searching.
-
10.1093/nar/gkp335, 2703892, 19458158
-
Bailey TL, Boden M, Buske FA, Frith M, Grant CE, Clementi L, Ren J, Li WW, Noble WS. MEME SUITE: tools for motif discovery and searching. Nucleic Acids Res 2009, 37:W202-208. 10.1093/nar/gkp335, 2703892, 19458158.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Bailey, T.L.1
Boden, M.2
Buske, F.A.3
Frith, M.4
Grant, C.E.5
Clementi, L.6
Ren, J.7
Li, W.W.8
Noble, W.S.9
-
19
-
-
30344478870
-
A global map of p53 transcription-factor binding sites in the human genome.
-
10.1016/j.cell.2005.10.043, 16413492
-
Wei CL, Wu Q, Vega VB, Chiu KP, Ng P, Zhang T, Shahab A, Yong HC, Fu Y, Weng Z, Liu J, Zhao XD, Chew JL, Lee YL, Kuznetsov VA, Sung WK, Miller LD, Lim B, Liu ET, Yu Q, Ng HH, Ruan Y. A global map of p53 transcription-factor binding sites in the human genome. Cell 2006, 124:207-219. 10.1016/j.cell.2005.10.043, 16413492.
-
(2006)
Cell
, vol.124
, pp. 207-219
-
-
Wei, C.L.1
Wu, Q.2
Vega, V.B.3
Chiu, K.P.4
Ng, P.5
Zhang, T.6
Shahab, A.7
Yong, H.C.8
Fu, Y.9
Weng, Z.10
Liu, J.11
Zhao, X.D.12
Chew, J.L.13
Lee, Y.L.14
Kuznetsov, V.A.15
Sung, W.K.16
Miller, L.D.17
Lim, B.18
Liu, E.T.19
Yu, Q.20
Ng, H.H.21
Ruan, Y.22
more..
-
20
-
-
78751684800
-
MiRBase
-
miRBase. , http://www.mirbase.org/
-
-
-
-
21
-
-
9344235449
-
Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs.
-
10.1261/rna.7135204, 1370684, 15525708
-
Cai X, Hagedorn CH, Cullen BR. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 2004, 10:1957-1966. 10.1261/rna.7135204, 1370684, 15525708.
-
(2004)
RNA
, vol.10
, pp. 1957-1966
-
-
Cai, X.1
Hagedorn, C.H.2
Cullen, B.R.3
-
22
-
-
34547838179
-
Genome-wide mapping of RELA(p65) binding identifies E2F1 as a transcriptional activator recruited by NF-kappaB upon TLR4 activation.
-
10.1016/j.molcel.2007.06.038, 17707233
-
Lim CA, Yao F, Wong JJ, George J, Xu H, Chiu KP, Sung WK, Lipovich L, Vega VB, Chen J, Shahab A, Zhao XD, Hibberd M, Wei CL, Lim B, Ng HH, Ruan Y, Chin KC. Genome-wide mapping of RELA(p65) binding identifies E2F1 as a transcriptional activator recruited by NF-kappaB upon TLR4 activation. Mol Cell 2007, 27:622-635. 10.1016/j.molcel.2007.06.038, 17707233.
-
(2007)
Mol Cell
, vol.27
, pp. 622-635
-
-
Lim, C.A.1
Yao, F.2
Wong, J.J.3
George, J.4
Xu, H.5
Chiu, K.P.6
Sung, W.K.7
Lipovich, L.8
Vega, V.B.9
Chen, J.10
Shahab, A.11
Zhao, X.D.12
Hibberd, M.13
Wei, C.L.14
Lim, B.15
Ng, H.H.16
Ruan, Y.17
Chin, K.C.18
-
23
-
-
57749168828
-
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signaling in fibroblasts.
-
10.1038/nature07511, 19043405
-
Thum T, Gross C, Fiedler J, Fischer T, Kissler S, Bussen M, Galuppo P, Just S, Rottbauer W, Frantz S, Castoldi M, Soutschek J, Koteliansky V, Rosenwald A, Basson MA, Licht JD, Pena JT, Rouhanifard SH, Muckenthaler MU, Tuschl T, Martin GR, Bauersachs J, Engelhardt S. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signaling in fibroblasts. Nature 2008, 456:980-984. 10.1038/nature07511, 19043405.
-
(2008)
Nature
, vol.456
, pp. 980-984
-
-
Thum, T.1
Gross, C.2
Fiedler, J.3
Fischer, T.4
Kissler, S.5
Bussen, M.6
Galuppo, P.7
Just, S.8
Rottbauer, W.9
Frantz, S.10
Castoldi, M.11
Soutschek, J.12
Koteliansky, V.13
Rosenwald, A.14
Basson, M.A.15
Licht, J.D.16
Pena, J.T.17
Rouhanifard, S.H.18
Muckenthaler, M.U.19
Tuschl, T.20
Martin, G.R.21
Bauersachs, J.22
Engelhardt, S.23
more..
-
24
-
-
44849100198
-
NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha.
-
10.1038/nature06905, 2669289, 18432192
-
Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG, Karin M. NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature 2008, 453:807-811. 10.1038/nature06905, 2669289, 18432192.
-
(2008)
Nature
, vol.453
, pp. 807-811
-
-
Rius, J.1
Guma, M.2
Schachtrup, C.3
Akassoglou, K.4
Zinkernagel, A.S.5
Nizet, V.6
Johnson, R.S.7
Haddad, G.G.8
Karin, M.9
-
25
-
-
33845321931
-
Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity.
-
10.1073/pnas.0602235103, 1643842, 17114296
-
Cummins EP, Berra E, Comerford KM, Ginouves A, Fitzgerald KT, Seeballuck F, Godson C, Nielsen JE, Moynagh P, Pouyssegur J, Taylor CT. Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity. Proc Natl Acad Sci USA 2006, 103:18154-18159. 10.1073/pnas.0602235103, 1643842, 17114296.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18154-18159
-
-
Cummins, E.P.1
Berra, E.2
Comerford, K.M.3
Ginouves, A.4
Fitzgerald, K.T.5
Seeballuck, F.6
Godson, C.7
Nielsen, J.E.8
Moynagh, P.9
Pouyssegur, J.10
Taylor, C.T.11
-
26
-
-
37049002653
-
Hypoxia up-regulates hypoxia-inducible factor-1alpha transcription by involving phosphatidylinositol 3-kinase and nuclear factor kappaB in pulmonary artery smooth muscle cells.
-
10.1091/mbc.E07-04-0391, 2096613, 17898080
-
Belaiba RS, Bonello S, Zähringer C, Schmidt S, Hess J, Kietzmann T, Görlach A. Hypoxia up-regulates hypoxia-inducible factor-1alpha transcription by involving phosphatidylinositol 3-kinase and nuclear factor kappaB in pulmonary artery smooth muscle cells. Mol Biol Cell 2007, 18:4691-4697. 10.1091/mbc.E07-04-0391, 2096613, 17898080.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 4691-4697
-
-
Belaiba, R.S.1
Bonello, S.2
Zähringer, C.3
Schmidt, S.4
Hess, J.5
Kietzmann, T.6
Görlach, A.7
-
27
-
-
0037295377
-
Discovery of quinazolines as a novel structural class of potent inhibitors of NF-kappa B activation.
-
10.1016/S0968-0896(02)00440-6, 12517433
-
Tobe M, Isobe Y, Tomizawa H, Nagasaki T, Takahashi H, Hayashi H. Discovery of quinazolines as a novel structural class of potent inhibitors of NF-kappa B activation. Bioorg Med Chem 2003, 11:383-391. 10.1016/S0968-0896(02)00440-6, 12517433.
-
(2003)
Bioorg Med Chem
, vol.11
, pp. 383-391
-
-
Tobe, M.1
Isobe, Y.2
Tomizawa, H.3
Nagasaki, T.4
Takahashi, H.5
Hayashi, H.6
-
28
-
-
33744950174
-
Nuclear factor-kappaB activated by capacitative Ca2+ entry enhances muscarinic receptor-mediated soluble amyloid precursor protein (sAPPalpha) release in SH-SY5Y cells.
-
10.1074/jbc.M601018200, 16490783
-
Choi S, Kim JH, Roh EJ, Ko MJ, Jung JE, Kim HJ. Nuclear factor-kappaB activated by capacitative Ca2+ entry enhances muscarinic receptor-mediated soluble amyloid precursor protein (sAPPalpha) release in SH-SY5Y cells. J Biol Chem 2006, 281:12722-12728. 10.1074/jbc.M601018200, 16490783.
-
(2006)
J Biol Chem
, vol.281
, pp. 12722-12728
-
-
Choi, S.1
Kim, J.H.2
Roh, E.J.3
Ko, M.J.4
Jung, J.E.5
Kim, H.J.6
-
29
-
-
76249120134
-
Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity.
-
10.1038/nm.2087, 20081863
-
Clarke TB, Davis KM, Lysenko ES, Zhou AY, Yu Y, Weiser JN. Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity. Nat Med 2010, 16:228-231. 10.1038/nm.2087, 20081863.
-
(2010)
Nat Med
, vol.16
, pp. 228-231
-
-
Clarke, T.B.1
Davis, K.M.2
Lysenko, E.S.3
Zhou, A.Y.4
Yu, Y.5
Weiser, J.N.6
-
30
-
-
42249090353
-
MiR-21 gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism.
-
10.1016/j.jmb.2008.03.015, 18384814
-
Fujita S, Ito T, Mizutani T, Minoguchi S, Yamamichi N, Sakurai K, Iba H. miR-21 gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism. J Mol Biol 2008, 378:492-504. 10.1016/j.jmb.2008.03.015, 18384814.
-
(2008)
J Mol Biol
, vol.378
, pp. 492-504
-
-
Fujita, S.1
Ito, T.2
Mizutani, T.3
Minoguchi, S.4
Yamamichi, N.5
Sakurai, K.6
Iba, H.7
-
31
-
-
34447098370
-
A chromatin landmark and transcription initiation at most promoters in human cells.
-
10.1016/j.cell.2007.05.042, 17632057
-
Guenther MG, Levine SS, Boyer LA, Jaenisch R, Young RA. A chromatin landmark and transcription initiation at most promoters in human cells. Cell 2007, 130:77-88. 10.1016/j.cell.2007.05.042, 17632057.
-
(2007)
Cell
, vol.130
, pp. 77-88
-
-
Guenther, M.G.1
Levine, S.S.2
Boyer, L.A.3
Jaenisch, R.4
Young, R.A.5
-
32
-
-
84870647022
-
UCSC Genome Browser
-
UCSC Genome Browser. , http://genome.ucsc.edu
-
-
-
-
33
-
-
0242542517
-
Induction of protein synthesis in cardiac fibroblasts by cardiotrophin-1: integration of multiple signaling pathways.
-
10.1016/S0008-6363(03)00534-0, 14613866
-
Freed DH, Borowiec AM, Angelovska T, Dixon IM. Induction of protein synthesis in cardiac fibroblasts by cardiotrophin-1: integration of multiple signaling pathways. Cardiovasc Res 2003, 60:365-375. 10.1016/S0008-6363(03)00534-0, 14613866.
-
(2003)
Cardiovasc Res
, vol.60
, pp. 365-375
-
-
Freed, D.H.1
Borowiec, A.M.2
Angelovska, T.3
Dixon, I.M.4
-
34
-
-
34548039517
-
Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer.
-
10.1182/blood-2007-03-081133, 17496199
-
Löffler D, Brocke-Heidrich K, Pfeifer G, Stocsits C, Hackermüller J, Kretzschmar AK, Burger R, Gramatzki M, Blumert C, Bauer K, Cvijic H, Ullmann AK, Stadler PF, Horn F. Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer. Blood 2007, 110:1330-1333. 10.1182/blood-2007-03-081133, 17496199.
-
(2007)
Blood
, vol.110
, pp. 1330-1333
-
-
Löffler, D.1
Brocke-Heidrich, K.2
Pfeifer, G.3
Stocsits, C.4
Hackermüller, J.5
Kretzschmar, A.K.6
Burger, R.7
Gramatzki, M.8
Blumert, C.9
Bauer, K.10
Cvijic, H.11
Ullmann, A.K.12
Stadler, P.F.13
Horn, F.14
-
35
-
-
34250658084
-
Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity.
-
10.1073/pnas.0609757104, 1863497, 17463090
-
Siddiquee K, Zhang S, Guida WC, Blaskovich MA, Greedy B, Lawrence HR, Yip ML, Jove R, McLaughlin MM, Lawrence NJ, Sebti SM, Turkson J. Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity. Proc Natl Acad Sci USA 2007, 104:7391-7396. 10.1073/pnas.0609757104, 1863497, 17463090.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7391-7396
-
-
Siddiquee, K.1
Zhang, S.2
Guida, W.C.3
Blaskovich, M.A.4
Greedy, B.5
Lawrence, H.R.6
Yip, M.L.7
Jove, R.8
McLaughlin, M.M.9
Lawrence, N.J.10
Sebti, S.M.11
Turkson, J.12
-
36
-
-
0034689773
-
Role of NF-kappaB in p53-mediated programmed cell death.
-
10.1038/35009130, 10786798
-
Ryan KM, Ernst MK, Rice NR, Vousden KH. Role of NF-kappaB in p53-mediated programmed cell death. Nature 2000, 404:892-897. 10.1038/35009130, 10786798.
-
(2000)
Nature
, vol.404
, pp. 892-897
-
-
Ryan, K.M.1
Ernst, M.K.2
Rice, N.R.3
Vousden, K.H.4
-
37
-
-
0032532070
-
P53-mediated repression of nuclear factor-kappaB RelA via the transcriptional integrator p300.
-
Ravi R, Mookerjee B, van Hensbergen Y, Bedi GC, Giordano A, El-Deiry WS, Fuchs EJ, Bedi A. p53-mediated repression of nuclear factor-kappaB RelA via the transcriptional integrator p300. Cancer Res 1998, 58:4531-4536.
-
(1998)
Cancer Res
, vol.58
, pp. 4531-4536
-
-
Ravi, R.1
Mookerjee, B.2
van Hensbergen, Y.3
Bedi, G.C.4
Giordano, A.5
El-Deiry, W.S.6
Fuchs, E.J.7
Bedi, A.8
-
38
-
-
27644549634
-
Essential role of STAT3 in cytokine-driven NF-kappaB-mediated serum amyloid A gene expression.
-
10.1111/j.1365-2443.2005.00900.x, 16236134
-
Hagihara K, Nishikawa T, Sugamata Y, Song J, Isobe T, Taga T, Yoshizaki K. Essential role of STAT3 in cytokine-driven NF-kappaB-mediated serum amyloid A gene expression. Genes Cells 2005, 10:1051-1063. 10.1111/j.1365-2443.2005.00900.x, 16236134.
-
(2005)
Genes Cells
, vol.10
, pp. 1051-1063
-
-
Hagihara, K.1
Nishikawa, T.2
Sugamata, Y.3
Song, J.4
Isobe, T.5
Taga, T.6
Yoshizaki, K.7
-
39
-
-
0036797750
-
Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB.
-
10.1042/BJ20020588, 1222853, 12057007
-
Yu Z, Zhang W, Kone BC. Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB. Biochem J 2002, 367:97-105. 10.1042/BJ20020588, 1222853, 12057007.
-
(2002)
Biochem J
, vol.367
, pp. 97-105
-
-
Yu, Z.1
Zhang, W.2
Kone, B.C.3
-
40
-
-
34249868449
-
Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB.
-
10.1101/gad.1553707, 1877751, 17510282
-
Yang J, Liao X, Agarwal MK, Barnes L, Auron PE, Stark GR. Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB. Genes Dev 2007, 21:1396-1408. 10.1101/gad.1553707, 1877751, 17510282.
-
(2007)
Genes Dev
, vol.21
, pp. 1396-1408
-
-
Yang, J.1
Liao, X.2
Agarwal, M.K.3
Barnes, L.4
Auron, P.E.5
Stark, G.R.6
-
41
-
-
37449031461
-
Prevention of cardiac hypertrophy and heart failure by silencing of NF-kappaB.
-
10.1016/j.jmb.2007.10.006, 2277468, 18037434
-
Gupta S, Young D, Maitra RK, Gupta A, Popovic ZB, Yong SL, Mahajan A, Wang Q, Sen S. Prevention of cardiac hypertrophy and heart failure by silencing of NF-kappaB. J Mol Biol 2008, 375:637-649. 10.1016/j.jmb.2007.10.006, 2277468, 18037434.
-
(2008)
J Mol Biol
, vol.375
, pp. 637-649
-
-
Gupta, S.1
Young, D.2
Maitra, R.K.3
Gupta, A.4
Popovic, Z.B.5
Yong, S.L.6
Mahajan, A.7
Wang, Q.8
Sen, S.9
-
42
-
-
34548051362
-
Survival pathways in hypertrophy and heart failure: the gp130-STAT axis.
-
10.1007/s00395-007-0674-z, 17918316
-
Fischer P, Hilfiker-Kleiner D. Survival pathways in hypertrophy and heart failure: the gp130-STAT axis. Basic Res Cardiol 2007, 102:393-411. 10.1007/s00395-007-0674-z, 17918316.
-
(2007)
Basic Res Cardiol
, vol.102
, pp. 393-411
-
-
Fischer, P.1
Hilfiker-Kleiner, D.2
|