Evolutionary dynamics of BRCA1 alterations in breast tumorigenesis

Journal of Theoretical Biology

Volumn 273, Issue 1, 2011, Pages 207-215

  De Vargas Roditi, Laura ^a   Michor, Franziska ^b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Breast cancer; Moran model; Stochastic modeling

Indexed keywords

CANCER; GENE; GENETICS; NUMERICAL MODEL; STOCHASTICITY; TUMOR;

ARTICLE; BREAST CARCINOGENESIS; CONTROLLED STUDY; FAMILIAL CANCER; GENE INACTIVATION; GENE MUTATION; HETEROZYGOSITY; MATHEMATICAL MODEL; ONCOGENE; PRIORITY JOURNAL; SOMATIC MUTATION; TUMOR SUPPRESSOR GENE;

BRCA1 PROTEIN; BREAST NEOPLASMS; CELL TRANSFORMATION, NEOPLASTIC; EVOLUTION, MOLECULAR; FEMALE; HUMANS; MODELS, GENETIC; PRECANCEROUS CONDITIONS; STOCHASTIC PROCESSES;

EID: 78751645969     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2010.12.033     Document Type: Article

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