Autocrine signaling via A1 adenosine receptors causes downregulation of M2 receptors in adult rat atrial myocytes in vitro

Pflugers Archiv European Journal of Physiology

Volumn 461, Issue 1, 2011, Pages 165-176

  Littwitz, Christoph ^a,b   Timpert, Mathias ^a   Bender, Kirsten ^a   Pott, Lutz ^a   Kienitz, Marie Cécile ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

ACh; Adenosine; Adenosine receptor; Atrial myocyte; K+ currents; Muscarinic potassium channel; Muscarinic receptor

Indexed keywords

2 CHLORO 6 N CYCLOPENTYLADENOSINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE A1 RECEPTOR; ADENOSINE DEAMINASE; ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENOVIRUS VECTOR; CARBACHOL; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; MUSCARINIC M2 RECEPTOR;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CONTROLLED STUDY; ENZYME INHIBITION; GENE OVEREXPRESSION; GENE TARGETING; HEART ATRIUM MUSCLE; HEART MUSCLE CELL; IN VITRO STUDY; MEMBRANE CURRENT; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; RNA INTERFERENCE;

ADENOSINE; ADENOSINE A1 RECEPTOR AGONISTS; ADENOSINE A1 RECEPTOR ANTAGONISTS; ADENOSINE DEAMINASE; ADENOSINE DEAMINASE INHIBITORS; ADENOSINE MONOPHOSPHATE; ANIMALS; AUTOCRINE COMMUNICATION; CARBACHOL; CELLS, CULTURED; DOWN-REGULATION; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; HEART ATRIA; MUSCARINIC AGONISTS; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; RATS; RECEPTOR CROSS-TALK; RECEPTOR, ADENOSINE A1; RECEPTOR, MUSCARINIC M2; RNA INTERFERENCE; XANTHINES;

EID: 78751642916     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-010-0897-y     Document Type: Article

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