The dynamics of formation and action of the ternary complex revealed in living cells using a G-protein-gated K+ channel as a biosensor

Journal of Biological Chemistry

Volumn 278, Issue 12, 2003, Pages 10851-10858

  Benians, Amy ^a   Leaney, Joanne L ^a   Milligan, Graeme ^b   Tinker, Andrew ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BIOSENSORS; COMPLEXATION; TERNARY SYSTEMS;

CHANNEL ACTIVATION;

CELLS;

4 AMINOBUTYRIC ACID B RECEPTOR; ADENOSINE A2 RECEPTOR; ALPHA 2A ADRENERGIC RECEPTOR; DOPAMINE 2 RECEPTOR; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; ISOPROTEIN; MUSCARINIC M4 RECEPTOR; PERTUSSIS TOXIN; PROTEIN SUBUNIT; CELL SURFACE RECEPTOR; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; POTASSIUM CHANNEL;

AGONIST; ARTICLE; BIOSENSOR; CELL VIABILITY; CHANNEL GATING; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; FLUORESCENCE; HUMAN; HUMAN CELL; KINETICS; PATCH CLAMP; PRIORITY JOURNAL; CELL LINE; CHEMISTRY; GENETIC PROCEDURES; METABOLISM; PHYSIOLOGY;

BIOSENSING TECHNIQUES; CELL LINE; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; ION CHANNEL GATING; KINETICS; PERTUSSIS TOXIN; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTORS, CELL SURFACE;

EID: 0038237526     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212299200     Document Type: Article

References (45)

1. Gilman, A. G. (1987) Annu. Rev. Biochem. 56, 615-649
2. Kenakin, T. (2002) Annu. Rev. Pharmacol. Toxicol. 42, 349-379
3. Shea, L., and Linderman, J. J. (1997) Biochem. Pharmacol. 53, 519-530
4. Christopoulos, A., and Kenakin, T. (2002) Pharmacol. Rev. 54, 323-374
5. Kenakin, T. (1996) Pharmacol. Rev. 48, 413-463
6. Kenakin, T. (1997) Trends Pharmacol. Sci. 18, 416-4177
7. Shea, L. D., Neubig, R. R., and Linderman, J. J. (2000) Life Sci. 68, 647-658
8. Noma, A., and Trautwein, W. (1978) Pflugers Arch. 377, 193-200
9. Wickman, K., Nemec, J., Gendler, S. J., and Clapham, D. E. (1998) Neuron 20, 103-114
10. Drici, M. D., Diochot, S., Terrenoire, C., Romey, G., and Lazdunski, M. (2000) Br. J. Pharmacol. 131, 569-577
11. Soejima, M., and Noma, A. (1984) Pflugers Arch. 400, 424-431
12. Breitwieser, G. E., and Szabo, G. (1985) Nature 317, 538-540
13. Pfaffinger, P. J., Martin, J. M., Hunter, D. D., Nathanson, N. M., and Hille, B. (1985) Nature 317, 536-538
14. Luscher, C., Jan, L. Y., Stoffel, M., Malenka, R. C., and Nicoll, R. A. (1997) Neuron 19, 687-695
15. Sodickson, D. L., and Bean, B. P. (1998) J. Neurosci. 18, 8153-8162
16. Yamada, M., Inanobe, A., and Kurachi, Y. (1998) Pharmacol. Rev. 50, 723-757
17. Kubo, Y., Reuveny, E., Slesinger, P. A., Jan, Y. N., and Jan, L. Y. (1993) Nature 364, 802-806
18. Dascal, N., Schreibmayer, W., Lim, N. F., Wang, W., Chavkin, C., DiMagno, L., Labarca, C., Kieffer, B. L., Gaveriaux-Ruff, C., Trollinger, D., Lester, H. A., and Davidson, N. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 10235-10239
19. Krapivinsky, G., Gordon, E. A., Wickman, K., Velimirovic, B., Krapivinsky, L., and Clapham, D. E. (1995) Nature 374, 135-141
20. Lesage, F., Duprat, F., Fink, M., Guillemare, E., Coppola, T., Lazdunski, M., and Hugnot, J. P. (1994) FEBS Lett. 353, 37-42
21. Chan, K. W., Langan, M. N., Sui, J. L., Kozak, J. A., Pabon, A., Ladias, J. A., and Logothetis, D. E. (1996) J. Gen. Physiol. 107, 381-397
22. Inanobe, A., Yoshimoto, Y., Horio, Y., Morishige, K.-I., Hibino, H., Matsumoto, S., Tokunaga, Y., Maeda, T., Hata, Y., Takai, Y., and Kurachi, Y. (1999) J. Neurosci. 19, 1006-1017
23. Jelacic, T. M., Sims, S. M., and Clapham, D. E. (1999) J. Membr. Biol. 169, 123-129
24. Logothetis, D. E., Kurachi, Y., Galper, J., Neer, E. J., and Clapham, D. E. (1987) Nature 325, 321-326
25. Reuveny, E., Slesinger, P. A., Inglese, J., Morales, J. M., Iniguez Lluhi, J. A., Lefkowitz, R. J., Bourne, H. R., Jan, Y. N., and Jan, L. Y. (1994) Nature 370, 143-146
26. Leaney, J. L., Milligan, G., and Tinker, A. (2000) J. Biol. Chem. 275, 921-929
27. Leaney, J. L., and Tinker, A. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 5651-5656
28. Leaney, J. L., Benians, A., Graves, F. M., and Tinker, A. (2002) J. Biol. Chem. 277, 28803-28809
29. Wise, A., Sheehan, M., Rees, S., Lee, M., and Milligan, G. (1999) Biochemistry 38, 2272-2278
30. Giblin, J. P., Leaney, J. L., and Tinker, A. (1999) J. Biol. Chem. 274, 22652-22659
31. Leaney, J. L., Dekker, L. V., and Tinker, A. (2001) J. Physiol. (Lond.) 534, 367-379
32. Sodickson, D. L., and Bean, B. P. (1996) J. Neurosci. 16, 6374-6385
33. Krapivinsky, G., Krapivinsky, L., Wickman, K., and Clapham, D. E. (1995) J. Biol. Chem. 270, 29059-29062
34. Sadja, R., Alagem, N., and Reuveny, E. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 10783-10788
35. Bahia, D. S., Wise, A., Fanelli, F., Lee, M., Rees, S., and Milligan, G. (1998) Biochemistry 37, 11555-11562
36. Waldhoer, M., Wise, A., Milligan, G., Freissmuth, M., and Nanoff, C. (1999) J. Biol. Chem. 274, 30571-30579
37. Vorobiov, D., Bera, A. K., Keren-Raifman, T., Barzilai, R., and Dascal, N. (2000) J. Biol. Chem. 275, 4166-4170
38. Yang, Q., and Lanier, S. M. (1999) Mol. Pharmacol. 56, 651-656
39. Zhang, Q., Pacheco, M. A., and Doupnik, C. A. (2002) J. Physiol. 545, 355-373
40. Huang, C. L., Slesinger, P. A., Casey, P. J., Jan, Y. N., and Jan, L. Y. (1995) Neuron 15, 1133-1143
41. Peleg, S., Varon, D., Ivanina, T., Dessauer, C. W., and Dascal, N. (2002) Neuron 33, 87-99
42. Lavine, N., Ethier, N., Oak, J. N., Pei, L., Liu, F., Trieu, P., Rebois, R. V., Bouvier, M., Hebert, T. E., and Van Tol, H. H. (2002) J. Biol. Chem. 277, 46010-46019
43. Greif, G. J., Sodickson, D. L., Bean, B. P., Neer, E. J., and Mende, U. (2000) J. Neurophysiol. 83, 1010-1018
44. Jackson, V. N., Bahia, D. S., and Milligan, G. (1999) Mol. Pharmacol. 55, 195-201
45. Jeong, S.-W., and Ikeda, S. R. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 907-912