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Volumn 13, Issue 1, 2011, Pages 1-16

Factor v Leiden thrombophilia

Author keywords

anticoagulation; APC resistance; Factor V Leiden; thrombophilia; venous thrombosis

Indexed keywords

ACTIVATED PROTEIN C; ALANINE; ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR; BLOOD CLOTTING FACTOR 11; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 5 LEIDEN; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; ESTROGEN; GLYCINE; HEPARIN; HOMOCYSTEINE; LOW MOLECULAR WEIGHT HEPARIN; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); ORAL CONTRACEPTIVE AGENT; PHOSPHOLIPID ANTIBODY; PROTHROMBIN; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN;

EID: 78751615186     PISSN: 10983600     EISSN: None     Source Type: Journal    
DOI: 10.1097/GIM.0b013e3181faa0f2     Document Type: Review
Times cited : (241)

References (209)
  • 1
    • 0027446268 scopus 로고
    • Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: Prediction of a cofactor to activated protein C
    • Dahlback B, Carlsson M, Svensson PJ. Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C. Proc Natl Acad Sci USA 1993;90:1004-1008.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1004-1008
    • Dahlback, B.1    Carlsson, M.2    Svensson, P.J.3
  • 2
    • 0028314865 scopus 로고
    • Mutation in blood coagulation factor v associated with resistance to activated protein C
    • Bertina RM, Koeleman BP, Koster T, et al. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994; 369:64-67.
    • (1994) Nature , vol.369 , pp. 64-67
    • Bertina, R.M.1    Koeleman, B.P.2    Koster, T.3
  • 3
    • 0028910906 scopus 로고
    • Mutation in the gene coding for coagulation factor v and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men
    • Ridker PM, Hennekens CH, Lindpaintner K, Stampfer MJ, Eisenberg PR, Miletich JP. Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men. N Engl J Med 1995;332:912-917.
    • (1995) N Engl J Med , vol.332 , pp. 912-917
    • Ridker, P.M.1    Hennekens, C.H.2    Lindpaintner, K.3    Stampfer, M.J.4    Eisenberg, P.R.5    Miletich, J.P.6
  • 4
    • 0028931717 scopus 로고
    • High risk of thrombosis in patients homozygous for factor v Leiden (activated protein C resistance)
    • Rosendaal FR, Koster T, Vandenbroucke JP, Reitsma PH. High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance). Blood 1995;85:1504-1508.
    • (1995) Blood , vol.85 , pp. 1504-1508
    • Rosendaal, F.R.1    Koster, T.2    Vandenbroucke, J.P.3    Reitsma, P.H.4
  • 5
    • 47249084343 scopus 로고    scopus 로고
    • Advances in understanding pathogenic mechanisms of throm-bophilic disorders
    • Dahlback B. Advances in understanding pathogenic mechanisms of throm-bophilic disorders. Blood 2008;112:19-27.
    • (2008) Blood , vol.112 , pp. 19-27
    • Dahlback, B.1
  • 6
    • 34548698444 scopus 로고    scopus 로고
    • Coagulation factor v and thrombophilia: Background and mechanisms
    • Segers K, Dahlback B, Nicolaes GA. Coagulation factor V and thrombophilia: background and mechanisms. Thromb Haemost 2007;98:530-542.
    • (2007) Thromb Haemost , vol.98 , pp. 530-542
    • Segers, K.1    Dahlback, B.2    Nicolaes, G.A.3
  • 7
    • 0029999292 scopus 로고    scopus 로고
    • Heightened thrombin generation in individuals with resistance to activated protein C
    • Martinelli I, Bottasso B, Duca F, Faioni E, Mannucci PM. Heightened thrombin generation in individuals with resistance to activated protein C. Thromb Haemost 1996;75:703-705.
    • (1996) Thromb Haemost , vol.75 , pp. 703-705
    • Martinelli, I.1    Bottasso, B.2    Duca, F.3    Faioni, E.4    Mannucci, P.M.5
  • 8
    • 0029878085 scopus 로고    scopus 로고
    • Elevated levels of prothrombin activation fragment 1 + 2 in plasma from patients with heterozygous Arg506 to Gln mutation in the factor v gene (APC-resistance) and/or inherited protein S deficiency
    • Zoller B, Holm J, Svensson P, Dahlback B. Elevated levels of prothrombin activation fragment 1 + 2 in plasma from patients with heterozygous Arg506 to Gln mutation in the factor V gene (APC-resistance) and/or inherited protein S deficiency. Thromb Haemost 1996;75:270-274.
    • (1996) Thromb Haemost , vol.75 , pp. 270-274
    • Zoller, B.1    Holm, J.2    Svensson, P.3    Dahlback, B.4
  • 9
    • 70349835752 scopus 로고    scopus 로고
    • Prevalence of factor v Leiden and prothrombin G20210A mutation in a large French population selected for nonthrombotic history: Geographical and age distribution
    • Mazoyer E, Ripoll L, Gueguen R, et al. Prevalence of factor V Leiden and prothrombin G20210A mutation in a large French population selected for nonthrombotic history: geographical and age distribution. Blood Coagul Fibrinolysis 2009;20:503-510.
    • (2009) Blood Coagul Fibrinolysis , vol.20 , pp. 503-510
    • Mazoyer, E.1    Ripoll, L.2    Gueguen, R.3
  • 10
    • 0028810738 scopus 로고
    • World distribution of factor v Leiden
    • Rees DC, Cox M, Clegg JB. World distribution of factor V Leiden. Lancet 1995;346:1133-1134.
    • (1995) Lancet , vol.346 , pp. 1133-1134
    • Rees, D.C.1    Cox, M.2    Clegg, J.B.3
  • 11
    • 0030955080 scopus 로고    scopus 로고
    • Ethnic distribution of factor v Leiden in 4047 men and women. Implications for venous thromboembolism screening
    • Ridker PM, Miletich JP, Hennekens CH, Buring JE. Ethnic distribution of factor V Leiden in 4047 men and women. Implications for venous thromboembolism screening. JAMA 1997;277:1305-1307.
    • (1997) JAMA , vol.277 , pp. 1305-1307
    • Ridker, P.M.1    Miletich, J.P.2    Hennekens, C.H.3    Buring, J.E.4
  • 12
    • 0030587024 scopus 로고    scopus 로고
    • High prevalence of the FVR506Q mutation causing APC resistance in a region of southern Sweden with a high incidence of venous thrombosis
    • Zoller B, Norlund L, Leksell H, et al. High prevalence of the FVR506Q mutation causing APC resistance in a region of southern Sweden with a high incidence of venous thrombosis. Thromb Res 1996;83:475-477.
    • (1996) Thromb Res , vol.83 , pp. 475-477
    • Zoller, B.1    Norlund, L.2    Leksell, H.3
  • 13
    • 0029090538 scopus 로고
    • APC-resistance and Mnl i genotype (Gln 506) of coagulation factor v are rare in Japanese population
    • Takamiya O, Ishida F, Kodaira H, Kitano K. APC-resistance and Mnl I genotype (Gln 506) of coagulation factor V are rare in Japanese population. Thromb Haemost 1995;74:996.
    • (1995) Thromb Haemost , vol.74 , pp. 996
    • Takamiya, O.1    Ishida, F.2    Kodaira, H.3    Kitano, K.4
  • 14
    • 0033843870 scopus 로고    scopus 로고
    • The prevalence of factor v R506Q mutation-Leiden among apparently healthy Lebanese
    • Irani-Hakime N, Tamim H, Kreidy R, Almawi WY. The prevalence of factor V R506Q mutation-Leiden among apparently healthy Lebanese. Am J Hematol 2000;65:45-49.
    • (2000) Am J Hematol , vol.65 , pp. 45-49
    • Irani-Hakime, N.1    Tamim, H.2    Kreidy, R.3    Almawi, W.Y.4
  • 15
    • 0032922667 scopus 로고    scopus 로고
    • High prevalence of factor v Leiden in healthy Jordanian Arabs
    • Awidi A, Shannak M, Bseiso A, et al. High prevalence of factor V Leiden in healthy Jordanian Arabs. Thromb Haemost 1999;81:582-584.
    • (1999) Thromb Haemost , vol.81 , pp. 582-584
    • Awidi, A.1    Shannak, M.2    Bseiso, A.3
  • 16
    • 0029846489 scopus 로고    scopus 로고
    • Prevalence of factor v Leiden in a Canadian blood donor population
    • Lee DH, Henderson PA, Blajchman MA. Prevalence of factor V Leiden in a Canadian blood donor population. CMAJ 1996;155:285-289.
    • (1996) CMAJ , vol.155 , pp. 285-289
    • Lee, D.H.1    Henderson, P.A.2    Blajchman, M.A.3
  • 17
    • 44649129978 scopus 로고    scopus 로고
    • Prevalence of factor v Leiden (G1691A) and prothrombin (G20210A) among Kurdish population from Western Iran
    • Rahimi Z, Vaisi-Raygani A, Mozafari H, Kharrazi H, Rezaei M, Nagel RL. Prevalence of factor V Leiden (G1691A) and prothrombin (G20210A) among Kurdish population from Western Iran. J Thromb Thrombolysis 2008;25:280-283.
    • (2008) J Thromb Thrombolysis , vol.25 , pp. 280-283
    • Rahimi, Z.1    Vaisi-Raygani, A.2    Mozafari, H.3    Kharrazi, H.4    Rezaei, M.5    Nagel, R.L.6
  • 18
    • 0031023757 scopus 로고    scopus 로고
    • A single genetic origin for a common Caucasian risk factor for venous thrombosis
    • Zivelin A, Griffin JH, Xu X, et al. A single genetic origin for a common Caucasian risk factor for venous thrombosis. Blood 1997;89:397-402.
    • (1997) Blood , vol.89 , pp. 397-402
    • Zivelin, A.1    Griffin, J.H.2    Xu, X.3
  • 19
    • 0035487920 scopus 로고    scopus 로고
    • Improved hemoglobin status and reduced menstrual blood loss among female carriers of factor v Leiden-an evolutionary advantage?
    • Lindqvist PG, Zoller B, Dahlback B. Improved hemoglobin status and reduced menstrual blood loss among female carriers of factor V Leiden-an evolutionary advantage? Thromb Haemost 2001;86:1122-1123.
    • (2001) Thromb Haemost , vol.86 , pp. 1122-1123
    • Lindqvist, P.G.1    Zoller, B.2    Dahlback, B.3
  • 20
    • 0031594157 scopus 로고    scopus 로고
    • Factor v Q506 mutation (activated protein C resistance) associated with reduced intrapartum blood loss-a possible evolutionary selection mechanism
    • Lindqvist PG, Svensson PJ, Dahlback B, Marsal K. Factor V Q506 mutation (activated protein C resistance) associated with reduced intrapartum blood loss-a possible evolutionary selection mechanism. Thromb Haemost 1998;79:69-73.
    • (1998) Thromb Haemost , vol.79 , pp. 69-73
    • Lindqvist, P.G.1    Svensson, P.J.2    Dahlback, B.3    Marsal, K.4
  • 22
    • 0029820281 scopus 로고    scopus 로고
    • Moderation of hemophilia A phenotype by the factor v R506Q mutation
    • Nichols WC, Amano K, Cacheris PM, et al. Moderation of hemophilia A phenotype by the factor V R506Q mutation. Blood 1996;88:1183-1187.
    • (1996) Blood , vol.88 , pp. 1183-1187
    • Nichols, W.C.1    Amano, K.2    Cacheris, P.M.3
  • 23
    • 0034016852 scopus 로고    scopus 로고
    • Effect of the factor v Leiden mutation on the clinical expression of severe hemophilia A
    • Lee DH, Walker IR, Teitel J, et al. Effect of the factor V Leiden mutation on the clinical expression of severe hemophilia A. Thromb Haemost 2000;83:387-391.
    • (2000) Thromb Haemost , vol.83 , pp. 387-391
    • Lee, D.H.1    Walker, I.R.2    Teitel, J.3
  • 24
    • 0029846341 scopus 로고    scopus 로고
    • Improved characteristics of aPC-resistance assay: Coatest aPC resistance by predilution of samples with factor v deficient plasma
    • Kapiotis S, Quehenberger P, Jilma B, et al. Improved characteristics of aPC-resistance assay: Coatest aPC resistance by predilution of samples with factor V deficient plasma. Am J Clin Pathol 1996;106:588-593.
    • (1996) Am J Clin Pathol , vol.106 , pp. 588-593
    • Kapiotis, S.1    Quehenberger, P.2    Jilma, B.3
  • 25
    • 0035746675 scopus 로고    scopus 로고
    • American College of Medical Genetics consensus statement on factor v Leiden mutation testing
    • ACMG Factor V Leiden Working Group
    • Grody WW, Griffin JH, Taylor AK, Korf BR, Heit JA, ACMG Factor V Leiden Working Group. American College of Medical Genetics consensus statement on factor V Leiden mutation testing. Genet Med 2001;3:139-148.
    • (2001) Genet Med , vol.3 , pp. 139-148
    • Grody, W.W.1    Griffin, J.H.2    Taylor, A.K.3    Korf, B.R.4    Heit, J.A.5
  • 26
    • 23744470442 scopus 로고    scopus 로고
    • Technical standards and guidelines: Venous thromboembolism (Factor v Leiden and prothrombin 20210G>A testing): A disease-specific supplement to the standards and guidelines for clinical genetics laboratories
    • Spector EB, Grody WW, Matteson CJ, et al. Technical standards and guidelines: venous thromboembolism (Factor V Leiden and prothrombin 20210G>A testing): a disease-specific supplement to the standards and guidelines for clinical genetics laboratories. Genet Med 2005;7:444-453.
    • (2005) Genet Med , vol.7 , pp. 444-453
    • Spector, E.B.1    Grody, W.W.2    Matteson, C.J.3
  • 27
    • 0036881044 scopus 로고    scopus 로고
    • Clinical utility of factor v Leiden (R506Q) testing for the diagnosis and management of thromboembolic disorders
    • Press RD, Bauer KA, Kujovich JL, Heit JA. Clinical utility of factor V Leiden (R506Q) testing for the diagnosis and management of thromboembolic disorders. Arch Pathol Lab Med 2002;126:1304-1318.
    • (2002) Arch Pathol Lab Med , vol.126 , pp. 1304-1318
    • Press, R.D.1    Bauer, K.A.2    Kujovich, J.L.3    Heit, J.A.4
  • 28
    • 0036305324 scopus 로고    scopus 로고
    • Laboratory testing for thrombophilia in pediatric patients: On behalf of the Subcommittee for Perinatal and Pediatric Thrombosis of the Scientific and Standardization Committee of the International Society of Thrombosis and Haemostasis (ISTH)
    • Manco-Johnson MJ, Grabowski EF, Hellgreen M, et al. Laboratory testing for thrombophilia in pediatric patients. On behalf of the Subcommittee for Perinatal and Pediatric Thrombosis of the Scientific and Standardization Committee of the International Society of Thrombosis and Haemostasis (ISTH). Thromb Haemost 2002;88:155-156. (Pubitemid 34752281)
    • (2002) Thrombosis and Haemostasis , vol.88 , Issue.1 , pp. 155-156
    • Manco-Johnson, M.J.1    Grabowski, E.F.2    Hellgreen, M.3    Kemahli, A.S.4    Massicotte, M.P.5    Muntean, W.6    Peters, M.7    Nowak-Gottl, U.8
  • 29
    • 45949094478 scopus 로고    scopus 로고
    • American College of Chest Physicians. Venous thromboembolism, thrombophilia, antithrombotic therapy, and pregnancy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    • Bates SM, Greer IA, Pabinger I, Sofaer S, Hirsh J, American College of Chest Physicians. Venous thromboembolism, thrombophilia, antithrombotic therapy, and pregnancy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008;133: 844S-886S.
    • (2008) Chest , vol.133
    • Bates, S.M.1    Greer, I.A.2    Pabinger, I.3    Sofaer, S.4    Hirsh, J.5
  • 30
    • 35548956390 scopus 로고    scopus 로고
    • Antithrombotic therapy and pregnancy: Consensus report and recommendations for prevention and treatment of venous thromboembolism and adverse pregnancy outcomes
    • Duhl AJ, Paidas MJ, Ural SH, et al. Antithrombotic therapy and pregnancy: consensus report and recommendations for prevention and treatment of venous thromboembolism and adverse pregnancy outcomes. Am J Obstet Gynecol 2007;197:457.e1-457.e21.
    • (2007) Am J Obstet Gynecol , vol.197
    • Duhl, A.J.1    Paidas, M.J.2    Ural, S.H.3
  • 31
    • 77949821581 scopus 로고    scopus 로고
    • Clinical guidelines for testing for heritable thrombophilia
    • Baglin T, Gray E, Greaves M, et al. Clinical guidelines for testing for heritable thrombophilia. Br J Haematol 2010;149:209-220.
    • (2010) Br J Haematol , vol.149 , pp. 209-220
    • Baglin, T.1    Gray, E.2    Greaves, M.3
  • 33
    • 67649160484 scopus 로고    scopus 로고
    • Predictive value of factor v Leiden and prothrombin G20210A in adults with venous thromboembolism and in family members of those with a mutation: A systematic review
    • Segal JB, Brotman DJ, Necochea AJ, et al. Predictive value of factor V Leiden and prothrombin G20210A in adults with venous thromboembolism and in family members of those with a mutation: a systematic review. JAMA 2009;301:2472-2485.
    • (2009) JAMA , vol.301 , pp. 2472-2485
    • Segal, J.B.1    Brotman, D.J.2    Necochea, A.J.3
  • 34
    • 0028037137 scopus 로고
    • Identification of the same factor v gene mutation in 47 out of 50 thrombosis-prone families with inherited resistance to activated protein C
    • Zoller B, Svensson PJ, He X, Dahlback B. Identification of the same factor V gene mutation in 47 out of 50 thrombosis-prone families with inherited resistance to activated protein C. J Clin Invest 1994;94:2521-2524.
    • (1994) J Clin Invest , vol.94 , pp. 2521-2524
    • Zoller, B.1    Svensson, P.J.2    He, X.3    Dahlback, B.4
  • 35
    • 20844435165 scopus 로고    scopus 로고
    • The incidence of venous thromboembolism among Factor v Leiden carriers: A community-based cohort study
    • Heit JA, Sobell JL, Li H, Sommer SS. The incidence of venous thromboembolism among Factor V Leiden carriers: a community-based cohort study. J Thromb Haemost 2005;3:305-311.
    • (2005) J Thromb Haemost , vol.3 , pp. 305-311
    • Heit, J.A.1    Sobell, J.L.2    Li, H.3    Sommer, S.S.4
  • 36
    • 0033760132 scopus 로고    scopus 로고
    • Factor v Leiden: The venous thrombotic risk in thrombophilic families
    • Lensen R, Rosendaal F, Vandenbroucke J, Bertina R. Factor V Leiden: the venous thrombotic risk in thrombophilic families. Br J Haematol 2000; 110:939-945.
    • (2000) Br J Haematol , vol.110 , pp. 939-945
    • Lensen, R.1    Rosendaal, F.2    Vandenbroucke, J.3    Bertina, R.4
  • 38
    • 0030968522 scopus 로고    scopus 로고
    • Mortality and causes of death in families with the factor v Leiden mutation (resistance to activated protein C)
    • Hille ET, Westendorp RG, Vandenbroucke JP, Rosendaal FR. Mortality and causes of death in families with the factor V Leiden mutation (resistance to activated protein C). Blood 1997;89:1963-1967.
    • (1997) Blood , vol.89 , pp. 1963-1967
    • Hille, E.T.1    Westendorp, R.G.2    Vandenbroucke, J.P.3    Rosendaal, F.R.4
  • 40
    • 67249127814 scopus 로고    scopus 로고
    • Thrombophilia testing in patients with venous thromboembolism. Findings from the RIETE registry
    • Roldan V, Lecumberri R, Munoz-Torrero JF, et al. Thrombophilia testing in patients with venous thromboembolism. Findings from the RIETE registry. Thromb Res 2009;124:174-177.
    • (2009) Thromb Res , vol.124 , pp. 174-177
    • Roldan, V.1    Lecumberri, R.2    Munoz-Torrero, J.F.3
  • 41
    • 77955927882 scopus 로고    scopus 로고
    • Thrombophilia and the risk of thromboembolic events in women on oral contraceptives and hormone replacement therapy
    • DeSancho MT, Dorff T, Rand JH. Thrombophilia and the risk of thromboembolic events in women on oral contraceptives and hormone replacement therapy. Blood Coagul Fibrinolysis 2010;21:534-538.
    • (2010) Blood Coagul Fibrinolysis , vol.21 , pp. 534-538
    • Desancho, M.T.1    Dorff, T.2    Rand, J.H.3
  • 42
    • 33645729527 scopus 로고    scopus 로고
    • Risk of recurrent venous thromboembolism in patients with common thrombophilia: A systematic review
    • Ho WK, Hankey GJ, Quinlan DJ, Eikelboom JW. Risk of recurrent venous thromboembolism in patients with common thrombophilia: a systematic review. Arch Intern Med 2006;166:729-736.
    • (2006) Arch Intern Med , vol.166 , pp. 729-736
    • Ho, W.K.1    Hankey, G.J.2    Quinlan, D.J.3    Eikelboom, J.W.4
  • 43
    • 51349124271 scopus 로고    scopus 로고
    • MAISTHRO registry. Hereditary and acquired thrombophilia in patients with upper extremity deep-vein thrombosis. Results from the MAISTHRO registry
    • Linnemann B, Meister F, Schwonberg J, Schindewolf M, Zgouras D, Lindhoff-Last E, MAISTHRO registry. Hereditary and acquired thrombophilia in patients with upper extremity deep-vein thrombosis. Results from the MAISTHRO registry. Thromb Haemost 2008;100:440-446.
    • (2008) Thromb Haemost , vol.100 , pp. 440-446
    • Linnemann, B.1    Meister, F.2    Schwonberg, J.3    Schindewolf, M.4    Zgouras, D.5    Lindhoff-Last, E.6
  • 44
    • 28444437698 scopus 로고    scopus 로고
    • Old and new risk factors for upper extremity deep venous thrombosis
    • Blom JW, Doggen CJ, Osanto S, Rosendaal FR. Old and new risk factors for upper extremity deep venous thrombosis. J Thromb Haemost 2005;3: 2471-2478.
    • (2005) J Thromb Haemost , vol.3 , pp. 2471-2478
    • Blom, J.W.1    Doggen, C.J.2    Osanto, S.3    Rosendaal, F.R.4
  • 47
    • 0029762332 scopus 로고    scopus 로고
    • Factor v Leiden mutation in cerebral venous thrombosis
    • Zuber M, Toulon P, Marnet L, Mas JL. Factor V Leiden mutation in cerebral venous thrombosis. Stroke 1996;27:1721-1723.
    • (1996) Stroke , vol.27 , pp. 1721-1723
    • Zuber, M.1    Toulon, P.2    Marnet, L.3    Mas, J.L.4
  • 49
    • 0029948169 scopus 로고    scopus 로고
    • Pulmonary embolism and deep venous thrombosis during pregnancy or oral contraceptive use: Prevalence of factor v Leiden
    • Hirsch DR, Mikkola KM, Marks PW, et al. Pulmonary embolism and deep venous thrombosis during pregnancy or oral contraceptive use: prevalence of factor V Leiden. Am Heart J 1996;131:1145-1148.
    • (1996) Am Heart J , vol.131 , pp. 1145-1148
    • Hirsch, D.R.1    Mikkola, K.M.2    Marks, P.W.3
  • 50
    • 0031726593 scopus 로고    scopus 로고
    • Genetic susceptibility to pregnancy-related venous thromboembolism: Roles of factor v Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations
    • Grandone E, Margaglione M, Colaizzo D, et al. Genetic susceptibility to pregnancy-related venous thromboembolism: roles of factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations. Am J Obstet Gynecol 1998;179:1324-1328.
    • (1998) Am J Obstet Gynecol , vol.179 , pp. 1324-1328
    • Grandone, E.1    Margaglione, M.2    Colaizzo, D.3
  • 51
    • 33846420184 scopus 로고    scopus 로고
    • An unfavorable combination of factor v Leiden with age, weight, and blood group causes high risk of pregnancy-associated venous thrombosis: A population-based nested case-control study
    • Hiltunen L, Rautanen A, Rasi V, et al. An unfavorable combination of factor V Leiden with age, weight, and blood group causes high risk of pregnancy-associated venous thrombosis: a population-based nested case-control study. Thromb Res 2007;119:423-432.
    • (2007) Thromb Res , vol.119 , pp. 423-432
    • Hiltunen, L.1    Rautanen, A.2    Rasi, V.3
  • 52
    • 36349021408 scopus 로고    scopus 로고
    • Risk of recurrence after a first venous thromboembolic event in young women
    • Laczkovics C, Grafenhofer H, Kaider A, et al. Risk of recurrence after a first venous thromboembolic event in young women. Haematologica 2007; 92:1201-1207.
    • (2007) Haematologica , vol.92 , pp. 1201-1207
    • Laczkovics, C.1    Grafenhofer, H.2    Kaider, A.3
  • 53
    • 0032767244 scopus 로고    scopus 로고
    • Throm-bophilic polymorphisms are common in women with fetal loss without apparent cause
    • Brenner B, Sarig G, Weiner Z, Younis J, Blumenfeld Z, Lanir N. Throm-bophilic polymorphisms are common in women with fetal loss without apparent cause. Thromb Haemost 1999;82:6-9.
    • (1999) Thromb Haemost , vol.82 , pp. 6-9
    • Brenner, B.1    Sarig, G.2    Weiner, Z.3    Younis, J.4    Blumenfeld, Z.5    Lanir, N.6
  • 54
    • 0005517354 scopus 로고    scopus 로고
    • Case-control study of the frequency of thrombophilic disorders in couples with late foetal loss and no throm-botic antecedent-the Nîmes Obstetricians and Haematologists Study5 (NOHA5)
    • Gris JC, Quéré I, Monpeyroux F, et al. Case-control study of the frequency of thrombophilic disorders in couples with late foetal loss and no throm-botic antecedent-the Nîmes Obstetricians and Haematologists Study5 (NOHA5). Thromb Haemost 1999;81:891-899.
    • (1999) Thromb Haemost , vol.81 , pp. 891-899
    • Gris, J.C.1    Quéré, I.2    Monpeyroux, F.3
  • 55
    • 0033531184 scopus 로고    scopus 로고
    • Increased frequency of genetic thrombophilia in women with complications of pregnancy
    • Kupferminc MJ, Eldor A, Steinman N, et al. Increased frequency of genetic thrombophilia in women with complications of pregnancy. N Engl J Med 1999;340:9-13.
    • (1999) N Engl J Med , vol.340 , pp. 9-13
    • Kupferminc, M.J.1    Eldor, A.2    Steinman, N.3
  • 56
    • 34548833298 scopus 로고    scopus 로고
    • Thrombophilia and location of venous thromboembolism
    • Schulman S. Thrombophilia and location of venous thromboembolism. J Thromb Haemost 2007;5:2151-2152.
    • (2007) J Thromb Haemost , vol.5 , pp. 2151-2152
    • Schulman, S.1
  • 58
    • 0033899336 scopus 로고    scopus 로고
    • Prevalence of factor v Leiden and prothrombin G20210A mutations in uns-elected patients with venous thromboembolism
    • de Moerloose P, Reber G, Perrier A, Perneger T, Bounameaux H. Prevalence of factor V Leiden and prothrombin G20210A mutations in uns-elected patients with venous thromboembolism. Br J Haematol 2000;110: 125-129.
    • (2000) Br J Haematol , vol.110 , pp. 125-129
    • De Moerloose, P.1    Reber, G.2    Perrier, A.3    Perneger, T.4    Bounameaux, H.5
  • 59
    • 33645510408 scopus 로고    scopus 로고
    • Thrombophilic abnormalities, oral contraceptives, and risk of cerebral vein thrombosis: A meta-analysis
    • Dentali F, Crowther M, Ageno W. Thrombophilic abnormalities, oral contraceptives, and risk of cerebral vein thrombosis: a meta-analysis. Blood 2006;107:2766-2773.
    • (2006) Blood , vol.107 , pp. 2766-2773
    • Dentali, F.1    Crowther, M.2    Ageno, W.3
  • 61
    • 67849104652 scopus 로고    scopus 로고
    • Genetics of venous thrombosis
    • Rosendaal FR, Reitsma PH. Genetics of venous thrombosis. J Thromb Haemost 2009;7(suppl 1):301-304.
    • (2009) J Thromb Haemost , vol.7 , Issue.SUPPL. 1 , pp. 301-304
    • Rosendaal, F.R.1    Reitsma, P.H.2
  • 62
    • 70350442915 scopus 로고    scopus 로고
    • The genetics of venous thromboembolism. A meta-analysis involving approximately 120,000 cases and 180,000 controls
    • Gohil R, Peck G, Sharma P. The genetics of venous thromboembolism. A meta-analysis involving approximately 120,000 cases and 180,000 controls. Thromb Haemost 2009;102:360-370.
    • (2009) Thromb Haemost , vol.102 , pp. 360-370
    • Gohil, R.1    Peck, G.2    Sharma, P.3
  • 63
    • 67149089651 scopus 로고    scopus 로고
    • Selective testing for thrombophilia in patients with first venous thrombosis: Results from a retrospective family cohort study on absolute thrombotic risk for currently known thrombophilic defects in 2479 relatives
    • Lijfering WM, Brouwer JL, Veeger NJ, et al. Selective testing for thrombophilia in patients with first venous thrombosis: results from a retrospective family cohort study on absolute thrombotic risk for currently known thrombophilic defects in 2479 relatives. Blood 2009;113: 5314-5322.
    • (2009) Blood , vol.113 , pp. 5314-5322
    • Lijfering, W.M.1    Brouwer, J.L.2    Veeger, N.J.3
  • 64
    • 0027520285 scopus 로고
    • Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study
    • Koster T, Rosendaal FR, de Ronde H, Briët E, Vandenbroucke JP, Bertina RM. Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study. Lancet 1993;342:1503-1506.
    • (1993) Lancet , vol.342 , pp. 1503-1506
    • Koster, T.1    Rosendaal, F.R.2    De Ronde, H.3    Briët, E.4    Vandenbroucke, J.P.5    Bertina, R.M.6
  • 66
    • 32544441595 scopus 로고    scopus 로고
    • Thrombophilia in pregnancy: A systematic review
    • Robertson L, Wu O, Langhorne P, et al. Thrombophilia in pregnancy: a systematic review. Br J Haematol 2006;132:171-196.
    • (2006) Br J Haematol , vol.132 , pp. 171-196
    • Robertson, L.1    Wu, O.2    Langhorne, P.3
  • 67
    • 40949151066 scopus 로고    scopus 로고
    • Pregnancy, the postpartum period and prothrombotic defects: Risk of venous thrombosis in the MEGA study
    • Pomp ER, Lenselink AM, Rosendaal FR, Doggen CJ. Pregnancy, the postpartum period and prothrombotic defects: risk of venous thrombosis in the MEGA study. J Thromb Haemost 2008;6:632-637.
    • (2008) J Thromb Haemost , vol.6 , pp. 632-637
    • Pomp, E.R.1    Lenselink, A.M.2    Rosendaal, F.R.3    Doggen, C.J.4
  • 68
    • 35748932957 scopus 로고    scopus 로고
    • The risk of recurrent venous thromboembolism among heterozygous carriers of factor v Leiden or prothrombin G20210A mutation. A systematic review of prospective studies
    • Marchiori A, Mosena L, Prins MH, Prandoni P. The risk of recurrent venous thromboembolism among heterozygous carriers of factor V Leiden or prothrombin G20210A mutation. A systematic review of prospective studies. Haematologica 2007;92:1107-1114.
    • (2007) Haematologica , vol.92 , pp. 1107-1114
    • Marchiori, A.1    Mosena, L.2    Prins, M.H.3    Prandoni, P.4
  • 69
    • 0036177333 scopus 로고    scopus 로고
    • Factor v Leiden and recurrent miscarriage-prospective outcome of untreated pregnancies
    • Rai R, Backos M, Elgaddal S, Shlebak A, Regan L. Factor V Leiden and recurrent miscarriage-prospective outcome of untreated pregnancies. Hum Reprod 2002;17:442-445.
    • (2002) Hum Reprod , vol.17 , pp. 442-445
    • Rai, R.1    Backos, M.2    Elgaddal, S.3    Shlebak, A.4    Regan, L.5
  • 70
    • 0037443934 scopus 로고    scopus 로고
    • Thrombophilic disorders and fetal loss: A meta-analysis
    • Rey E, Kahn SR, David M, Shrier I. Thrombophilic disorders and fetal loss: a meta-analysis. Lancet 2003;361:901-908.
    • (2003) Lancet , vol.361 , pp. 901-908
    • Rey, E.1    Kahn, S.R.2    David, M.3    Shrier, I.4
  • 71
    • 28444457264 scopus 로고    scopus 로고
    • Factor v Leiden and prothrombin G20210A polymorphisms as risk factors for miscarriage during a first intended pregnancy: The matched case-control 'NOHA first' study
    • Lissalde-Lavigne G, Fabbro-Peray P, Cochery-Nouvellon E, et al. Factor V Leiden and prothrombin G20210A polymorphisms as risk factors for miscarriage during a first intended pregnancy: the matched case-control 'NOHA first' study. J Thromb Haemost 2005;3:2178-2184.
    • (2005) J Thromb Haemost , vol.3 , pp. 2178-2184
    • Lissalde-Lavigne, G.1    Fabbro-Peray, P.2    Cochery-Nouvellon, E.3
  • 72
    • 1442357145 scopus 로고    scopus 로고
    • Factor v Leiden and the risk for venous thromboembolism in the adult Danish population
    • Juul K, Tybjaerg-Hansen A, Schnohr P, Nordestgaard BG. Factor V Leiden and the risk for venous thromboembolism in the adult Danish population. Ann Intern Med 2004;140:330-337.
    • (2004) Ann Intern Med , vol.140 , pp. 330-337
    • Juul, K.1    Tybjaerg-Hansen, A.2    Schnohr, P.3    Nordestgaard, B.G.4
  • 73
    • 0038299175 scopus 로고    scopus 로고
    • Effect of hemostatic risk factors on the individual probability of thrombosis during pregnancy and the puerperium
    • Gerhardt A, Scharf RE, Zotz RB. Effect of hemostatic risk factors on the individual probability of thrombosis during pregnancy and the puerperium. Thromb Haemost 2003;90:77-85.
    • (2003) Thromb Haemost , vol.90 , pp. 77-85
    • Gerhardt, A.1    Scharf, R.E.2    Zotz, R.B.3
  • 75
    • 0028029477 scopus 로고
    • Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor v Leiden mutation
    • Vandenbroucke JP, Koster T, Briët E, Reitsma PH, Bertina RM, Rosendaal FR. Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation. Lancet 1994;344:1453-1457.
    • (1994) Lancet , vol.344 , pp. 1453-1457
    • Vandenbroucke, J.P.1    Koster, T.2    Briët, E.3    Reitsma, P.H.4    Bertina, R.M.5    Rosendaal, F.R.6
  • 76
    • 6944234994 scopus 로고    scopus 로고
    • Impact of environmental and hereditary risk factors on the clinical manifestation of thrombophilia in homozygous carriers of factor V:G1691A
    • Ehrenforth S, Nemes L, Mannhalter C, et al. Impact of environmental and hereditary risk factors on the clinical manifestation of thrombophilia in homozygous carriers of factor V:G1691A. J Thromb Haemost 2004;2:430-436.
    • (2004) J Thromb Haemost , vol.2 , pp. 430-436
    • Ehrenforth, S.1    Nemes, L.2    Mannhalter, C.3
  • 77
    • 73349119138 scopus 로고    scopus 로고
    • Factor v Leiden homozygous genotype and pregnancy outcomes
    • Biron-Andréani C, Bauters A, Le Cam-Duchez V, et al. Factor V Leiden homozygous genotype and pregnancy outcomes. Obstet Gynecol 2009;114: 1249-1253.
    • (2009) Obstet Gynecol , vol.114 , pp. 1249-1253
    • Biron-Andréani, C.1    Bauters, A.2    Le Cam-Duchez, V.3
  • 78
    • 0030317948 scopus 로고    scopus 로고
    • The long-term clinical course of acute deep venous thrombosis
    • Prandoni P, Lensing AW, Cogo A, et al. The long-term clinical course of acute deep venous thrombosis. Ann Intern Med 1996;125:1-7.
    • (1996) Ann Intern Med , vol.125 , pp. 1-7
    • Prandoni, P.1    Lensing, A.W.2    Cogo, A.3
  • 80
    • 0042658340 scopus 로고    scopus 로고
    • Incidence of recurrent venous thromboembolism in relation to clinical and thrombophilic risk factors: Prospective cohort study
    • Baglin T, Luddington R, Brown K, Baglin C. Incidence of recurrent venous thromboembolism in relation to clinical and thrombophilic risk factors: prospective cohort study. Lancet 2003;362:523-526.
    • (2003) Lancet , vol.362 , pp. 523-526
    • Baglin, T.1    Luddington, R.2    Brown, K.3    Baglin, C.4
  • 81
    • 70449455518 scopus 로고    scopus 로고
    • Contribution of high factor VIII, IX and XI to the risk of recurrent venous thrombosis in factor v Leiden carriers
    • Lijfering WM, Christiansen SC, Rosendaal FR, Cannegieter SC. Contribution of high factor VIII, IX and XI to the risk of recurrent venous thrombosis in factor V Leiden carriers. J Thromb Haemost 2009;7:1944-1946.
    • (2009) J Thromb Haemost , vol.7 , pp. 1944-1946
    • Lijfering, W.M.1    Christiansen, S.C.2    Rosendaal, F.R.3    Cannegieter, S.C.4
  • 82
    • 58149393274 scopus 로고    scopus 로고
    • Influence of thrombophilia on risk of recurrent venous thromboembolism while on warfarin: Results from a randomized trial
    • Kearon C, Julian JA, Kovacs MJ, et al. Influence of thrombophilia on risk of recurrent venous thromboembolism while on warfarin: results from a randomized trial. Blood 2008;112:4432-4436.
    • (2008) Blood , vol.112 , pp. 4432-4436
    • Kearon, C.1    Julian, J.A.2    Kovacs, M.J.3
  • 83
    • 0033539096 scopus 로고    scopus 로고
    • The risk of recurrent deep venous thrombosis among heterozygous carriers of both factor v Leiden and the G20210A prothrombin mutation
    • De Stefano V, Martinelli I, Mannucci PM, et al. The risk of recurrent deep venous thrombosis among heterozygous carriers of both factor V Leiden and the G20210A prothrombin mutation. N Engl J Med 1999;341:801-806.
    • (1999) N Engl J Med , vol.341 , pp. 801-806
    • De Stefano, V.1    Martinelli, I.2    Mannucci, P.M.3
  • 84
    • 0032729187 scopus 로고    scopus 로고
    • Coexistence of factor v Leiden and Factor II A20210 mutations and recurrent venous thromboem-bolism
    • Margaglione M, D'Andrea G, Colaizzo D, et al. Coexistence of factor V Leiden and Factor II A20210 mutations and recurrent venous thromboem-bolism. Thromb Haemost 1999;82:1583-1587.
    • (1999) Thromb Haemost , vol.82 , pp. 1583-1587
    • Margaglione, M.1    D'Andrea, G.2    Colaizzo, D.3
  • 85
    • 0036190724 scopus 로고    scopus 로고
    • The incidence of recurrent venous thromboembolism in carriers of factor v Leiden is related to concomitant thrombophilic disorders
    • Meinardi JR, Middeldorp S, de Kam PJ, et al. The incidence of recurrent venous thromboembolism in carriers of factor V Leiden is related to concomitant thrombophilic disorders. Br J Haematol 2002;116:625-631.
    • (2002) Br J Haematol , vol.116 , pp. 625-631
    • Meinardi, J.R.1    Middeldorp, S.2    De Kam, P.J.3
  • 86
    • 77951428695 scopus 로고    scopus 로고
    • Risk of recurrent venous thrombosis in homozygous carriers and double heterozygous carriers of factor v Leiden and prothrombin G20210A
    • Lijfering WM, Middeldorp S, Veeger NJ, et al. Risk of recurrent venous thrombosis in homozygous carriers and double heterozygous carriers of factor V Leiden and prothrombin G20210A. Circulation 2010;121:1706-1712.
    • (2010) Circulation , vol.121 , pp. 1706-1712
    • Lijfering, W.M.1    Middeldorp, S.2    Veeger, N.J.3
  • 87
    • 0034610031 scopus 로고    scopus 로고
    • Mutations in coagulation factors in women with unexplained late fetal loss
    • Martinelli I, Taioli E, Cetin I, et al. Mutations in coagulation factors in women with unexplained late fetal loss. N Engl J Med 2000;343:1015-1018.
    • (2000) N Engl J Med , vol.343 , pp. 1015-1018
    • Martinelli, I.1    Taioli, E.2    Cetin, I.3
  • 88
    • 37349028049 scopus 로고    scopus 로고
    • The GOAL study: A prospective examination of the impact of factor v Leiden and ABO(H) blood groups on haemorrhagic and thrombotic pregnancy outcomes
    • Clark P, Walker ID, Govan L, Wu O, Greer IA. The GOAL study: a prospective examination of the impact of factor V Leiden and ABO(H) blood groups on haemorrhagic and thrombotic pregnancy outcomes. Br J Haematol 2008;140:236-240.
    • (2008) Br J Haematol , vol.140 , pp. 236-240
    • Clark, P.1    Walker, I.D.2    Govan, L.3    Wu, O.4    Greer, I.A.5
  • 90
    • 65549083856 scopus 로고    scopus 로고
    • Pregnancy outcome in women with factor v Leiden and recurrent miscarriage
    • Jivraj S, Makris M, Saravelos S, Li TC. Pregnancy outcome in women with factor V Leiden and recurrent miscarriage. BJOG 2009;116:995-998.
    • (2009) BJOG , vol.116 , pp. 995-998
    • Jivraj, S.1    Makris, M.2    Saravelos, S.3    Li, T.C.4
  • 91
    • 1842637313 scopus 로고    scopus 로고
    • The association between adverse pregnancy outcomes and maternal factor V Leiden genotype: A meta-analysis
    • Dudding TE, Attia J. The association between adverse pregnancy outcomes and maternal factor V Leiden genotype: a meta-analysis. Thromb Haemost 2004;91:700-711. (Pubitemid 38477450)
    • (2004) Thrombosis and Haemostasis , vol.91 , Issue.4 , pp. 700-711
    • Dudding, T.E.1    Attia, J.2
  • 92
    • 1542287296 scopus 로고    scopus 로고
    • Evaluation of the association between hereditary thrombophilias and recurrent pregnancy loss: A meta-analysis
    • Kovalevsky G, Gracia CR, Berlin JA, Sammel MD, Barnhart KT. Evaluation of the association between hereditary thrombophilias and recurrent pregnancy loss: a meta-analysis. Arch Intern Med 2004;164:558-563.
    • (2004) Arch Intern Med , vol.164 , pp. 558-563
    • Kovalevsky, G.1    Gracia, C.R.2    Berlin, J.A.3    Sammel, M.D.4    Barnhart, K.T.5
  • 93
    • 0032827489 scopus 로고    scopus 로고
    • The risk of fetal loss in family members of probands with factor v Leiden mutation
    • Tormene D, Simioni P, Prandoni P, et al. The risk of fetal loss in family members of probands with factor V Leiden mutation. Thromb Haemost 1999;82:1237-1239.
    • (1999) Thromb Haemost , vol.82 , pp. 1237-1239
    • Tormene, D.1    Simioni, P.2    Prandoni, P.3
  • 95
    • 77952548065 scopus 로고    scopus 로고
    • Factor v Leiden as risk factor for unexplained stillbirth-a population-based nested case-control study
    • Hiltunen LM, Laivuori H, Rautanen A, et al. Factor V Leiden as risk factor for unexplained stillbirth-a population-based nested case-control study. Thromb Res 2010;125:505-510.
    • (2010) Thromb Res , vol.125 , pp. 505-510
    • Hiltunen, L.M.1    Laivuori, H.2    Rautanen, A.3
  • 96
    • 0033040275 scopus 로고    scopus 로고
    • A possible role for activated protein C resistance in patients with first and second trimester pregnancy failure
    • Tal J, Schliamser LM, Leibovitz Z, Ohel G, Attias D. A possible role for activated protein C resistance in patients with first and second trimester pregnancy failure. Hum Reprod 1999;14:1624-1627.
    • (1999) Hum Reprod , vol.14 , pp. 1624-1627
    • Tal, J.1    Schliamser, L.M.2    Leibovitz, Z.3    Ohel, G.4    Attias, D.5
  • 97
    • 51649086196 scopus 로고    scopus 로고
    • Inherited thrombophilia and pregnancy complications revisited
    • Rodger MA, Paidas M, McLintock C, et al. Inherited thrombophilia and pregnancy complications revisited. Obstet Gynecol 2008;112:320-324.
    • (2008) Obstet Gynecol , vol.112 , pp. 320-324
    • Rodger, M.A.1    Paidas, M.2    McLintock, C.3
  • 98
    • 31944434778 scopus 로고    scopus 로고
    • Thrombophilia is significantly associated with severe preeclampsia: Results of a large-scale, case-controlled study
    • Mello G, Parretti E, Marozio L, et al. Thrombophilia is significantly associated with severe preeclampsia: results of a large-scale, case-controlled study. Hypertension 2005;46:1270-1274.
    • (2005) Hypertension , vol.46 , pp. 1270-1274
    • Mello, G.1    Parretti, E.2    Marozio, L.3
  • 99
    • 0032972632 scopus 로고    scopus 로고
    • Prothrombotic genetic risk factors and the occurrence of gestational hypertension with or without proteinuria
    • Grandone E, Margaglione M, Colaizzo D, et al. Prothrombotic genetic risk factors and the occurrence of gestational hypertension with or without proteinuria. Thromb Haemost 1999;81:349-352.
    • (1999) Thromb Haemost , vol.81 , pp. 349-352
    • Grandone, E.1    Margaglione, M.2    Colaizzo, D.3
  • 100
    • 54249125584 scopus 로고    scopus 로고
    • Factor v Leiden is associated with pre-eclampsia but not with fetal growth restriction: A genetic association study and meta-analysis
    • Dudding T, Heron J, Thakkinstian A, et al. Factor V Leiden is associated with pre-eclampsia but not with fetal growth restriction: a genetic association study and meta-analysis. J Thromb Haemost 2008;6:1869-1875.
    • (2008) J Thromb Haemost , vol.6 , pp. 1869-1875
    • Dudding, T.1    Heron, J.2    Thakkinstian, A.3
  • 101
    • 23944441722 scopus 로고    scopus 로고
    • The relationship of the factor v Leiden mutation and pregnancy outcomes for mother and fetus
    • Dizon-Townson D, Miller C, Sibai B, et al. The relationship of the factor V Leiden mutation and pregnancy outcomes for mother and fetus. Obstet Gynecol 2005;106:517-524.
    • (2005) Obstet Gynecol , vol.106 , pp. 517-524
    • Dizon-Townson, D.1    Miller, C.2    Sibai, B.3
  • 102
    • 58749116983 scopus 로고    scopus 로고
    • Inherited thrombophilia and pre-eclampsia within a multicenter cohort: The Montreal Preeclampsia Study
    • discussion e1-e5
    • Kahn SR, Platt R, McNamara H, et al. Inherited thrombophilia and pre-eclampsia within a multicenter cohort: the Montreal Preeclampsia Study. Am J Obstet Gynecol 2009;200:151.e1-151.e9; discussion e1-e5.
    • (2009) Am J Obstet Gynecol , vol.200
    • Kahn, S.R.1    Platt, R.2    McNamara, H.3
  • 103
    • 74049108191 scopus 로고    scopus 로고
    • Inherited thrombophilia polymorphisms and pregnancy outcomes in nulliparous women
    • Said JM, Higgins JR, Moses EK, et al. Inherited thrombophilia polymorphisms and pregnancy outcomes in nulliparous women. Obstet Gynecol 2010;115:5-13.
    • (2010) Obstet Gynecol , vol.115 , pp. 5-13
    • Said, J.M.1    Higgins, J.R.2    Moses, E.K.3
  • 104
    • 33646256586 scopus 로고    scopus 로고
    • Factor v Leiden pregnancy complications and adverse outcomes: The Hordaland Homocys-teine Study
    • Nurk E, Tell GS, Refsum H, Ueland PM, Vollset SE. Factor V Leiden, pregnancy complications and adverse outcomes: the Hordaland Homocys-teine Study. QJM 2006;99:289-298.
    • (2006) QJM , vol.99 , pp. 289-298
    • Nurk, E.1    Tell, G.S.2    Refsum, H.3    Ueland, P.M.4    Vollset, S.E.5
  • 105
    • 58149097240 scopus 로고    scopus 로고
    • Maternal thrombophilia and the risk of recurrence of preeclampsia
    • Facchinetti F, Marozio L, Frusca T, et al. Maternal thrombophilia and the risk of recurrence of preeclampsia. Am J Obstet Gynecol 2009;200:46.e1-46.e5.
    • (2009) Am J Obstet Gynecol , vol.200
    • Facchinetti, F.1    Marozio, L.2    Frusca, T.3
  • 106
    • 14644435132 scopus 로고    scopus 로고
    • A systematic review of the association between factor v Leiden or prothrombin gene variant and intrauterine growth restriction
    • Howley HE, Walker M, Rodger MA. A systematic review of the association between factor V Leiden or prothrombin gene variant and intrauterine growth restriction. Am J Obstet Gynecol 2005;192:694-708.
    • (2005) Am J Obstet Gynecol , vol.192 , pp. 694-708
    • Howley, H.E.1    Walker, M.2    Ma, R.3
  • 108
    • 0034840147 scopus 로고    scopus 로고
    • Combined effect of factor v Leiden and prothrombin 20210A on the risk of venous thromboembo-lism-pooled analysis of 8 case-control studies including 2310 cases and 3204 controls
    • Study Group for Pooled-Analysis in Venous Thromboem-bolism
    • Emmerich J, Rosendaal FR, Cattaneo M, et al. Combined effect of factor V Leiden and prothrombin 20210A on the risk of venous thromboembo-lism-pooled analysis of 8 case-control studies including 2310 cases and 3204 controls. Study Group for Pooled-Analysis in Venous Thromboem-bolism. Thromb Haemost 2001;86:809-816.
    • (2001) Thromb Haemost , vol.86 , pp. 809-816
    • Emmerich, J.1    Rosendaal, F.R.2    Cattaneo, M.3
  • 109
    • 0031016432 scopus 로고    scopus 로고
    • Arterial and venous thrombosis is not associated with the 4G/5G polymorphism in the promoter of the plasminogen activator inhibitor gene in a large cohort of US men
    • Ridker PM, Hennekens CH, Lindpaintner K, Stampfer MJ, Miletich JP. Arterial and venous thrombosis is not associated with the 4G/5G polymorphism in the promoter of the plasminogen activator inhibitor gene in a large cohort of US men. Circulation 1997;95:59-62.
    • (1997) Circulation , vol.95 , pp. 59-62
    • Ridker, P.M.1    Hennekens, C.H.2    Lindpaintner, K.3    Stampfer, M.J.4    Miletich, J.P.5
  • 110
    • 34848828529 scopus 로고    scopus 로고
    • Risk of venous thrombosis: Obesity and its joint effect with oral contraceptive use and prothrom-botic mutations
    • Pomp ER, le Cessie S, Rosendaal FR, Doggen CJ. Risk of venous thrombosis: obesity and its joint effect with oral contraceptive use and prothrom-botic mutations. Br J Haematol 2007;139:289-296.
    • (2007) Br J Haematol , vol.139 , pp. 289-296
    • Pomp, E.R.1    Le Cessie, S.2    Rosendaal, F.R.3    Doggen, C.J.4
  • 111
    • 0036623663 scopus 로고    scopus 로고
    • Venous thromboembolism in young women; Role of thrombophilic mutations and oral contraceptive use
    • Legnani C, Palareti G, Guazzaloca G, et al. Venous thromboembolism in young women; role of thrombophilic mutations and oral contraceptive use. Eur Heart J 2002;23:984-990.
    • (2002) Eur Heart J , vol.23 , pp. 984-990
    • Legnani, C.1    Palareti, G.2    Guazzaloca, G.3
  • 112
    • 0038180285 scopus 로고    scopus 로고
    • Risk of venous thromboembolism after air travel: Interaction with thrombophilia and oral contraceptives
    • Martinelli I, Taioli E, Battaglioli T, et al. Risk of venous thromboembolism after air travel: interaction with thrombophilia and oral contraceptives. Arch Intern Med 2003;163:2771-2774.
    • (2003) Arch Intern Med , vol.163 , pp. 2771-2774
    • Martinelli, I.1    Taioli, E.2    Battaglioli, T.3
  • 114
    • 0029609256 scopus 로고
    • Enhancement by factor v Leiden mutation of risk of deep-vein thrombosis associated with oral contraceptives containing a third-generation progestagen
    • Bloemenkamp KW, Rosendaal FR, Helmerhorst FM, Büller HR, Vanden-broucke JP. Enhancement by factor V Leiden mutation of risk of deep-vein thrombosis associated with oral contraceptives containing a third-generation progestagen. Lancet 1995;346:1593-1596.
    • (1995) Lancet , vol.346 , pp. 1593-1596
    • Bloemenkamp, K.W.1    Rosendaal, F.R.2    Helmerhorst, F.M.3    Büller, H.R.4    Vanden-Broucke, J.P.5
  • 115
    • 22144448238 scopus 로고    scopus 로고
    • Oral contraceptives, hormone replacement therapy, thrombophilias and risk of venous thromboembolism: A systematic review
    • The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) Study
    • Wu O, Robertson L, Langhorne P, et al. Oral contraceptives, hormone replacement therapy, thrombophilias and risk of venous thromboembolism: a systematic review. The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) Study. Thromb Haemost 2005;94: 17-25.
    • (2005) Thromb Haemost , vol.94 , pp. 17-25
    • Wu, O.1    Robertson, L.2    Langhorne, P.3
  • 116
    • 0036125032 scopus 로고    scopus 로고
    • Hormonal replacement therapy, prothrombotic mutations and the risk of venous thrombosis
    • Rosendaal FR, Vessey M, Rumley A, et al. Hormonal replacement therapy, prothrombotic mutations and the risk of venous thrombosis. Br J Haematol 2002;116:851-854.
    • (2002) Br J Haematol , vol.116 , pp. 851-854
    • Rosendaal, F.R.1    Vessey, M.2    Rumley, A.3
  • 117
    • 0036072092 scopus 로고    scopus 로고
    • Factor v Leiden, hormone replacement therapy, and risk of venous thromboembolic events in women with coronary disease
    • Herrington DM, Vittinghoff E, Howard TD, et al. Factor V Leiden, hormone replacement therapy, and risk of venous thromboembolic events in women with coronary disease. Arterioscler Thromb Vasc Biol 2002;22: 1012-1017.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1012-1017
    • Herrington, D.M.1    Vittinghoff, E.2    Howard, T.D.3
  • 118
    • 4644238003 scopus 로고    scopus 로고
    • Estrogen plus progestin and risk of venous thrombosis
    • Cushman M, Kuller LH, Prentice R, et al. Estrogen plus progestin and risk of venous thrombosis. JAMA 2004;292:1573-1580.
    • (2004) JAMA , vol.292 , pp. 1573-1580
    • Cushman, M.1    Kuller, L.H.2    Prentice, R.3
  • 119
    • 33748358835 scopus 로고    scopus 로고
    • Travel-related venous thrombosis: Results from a large population-based case control study (MEGA study)
    • Cannegieter SC, Doggen CJ, van Houwelingen HC, Rosendaal FR. Travel-related venous thrombosis: results from a large population-based case control study (MEGA study). PLoS Med 2006;3:e307.
    • (2006) PLoS Med , vol.3
    • Cannegieter, S.C.1    Doggen, C.J.2    Van Houwelingen, H.C.3    Rosendaal, F.R.4
  • 121
    • 0031893697 scopus 로고    scopus 로고
    • Clinical features of thrombo-philia in families with gene defects in protein C or protein S combined with factor v Leiden
    • Mustafa S, Mannhalter C, Rintelen C, et al. Clinical features of thrombo-philia in families with gene defects in protein C or protein S combined with factor V Leiden. Blood Coagul Fibrinolysis 1998;9:85-89.
    • (1998) Blood Coagul Fibrinolysis , vol.9 , pp. 85-89
    • Mustafa, S.1    Mannhalter, C.2    Rintelen, C.3
  • 122
    • 40949145685 scopus 로고    scopus 로고
    • Gene variants associated with deep vein thrombosis
    • Bezemer ID, Bare LA, Doggen CJ, et al. Gene variants associated with deep vein thrombosis. JAMA 2008;299:1306-1314.
    • (2008) JAMA , vol.299 , pp. 1306-1314
    • Bezemer, I.D.1    Bare, L.A.2    Doggen, C.J.3
  • 123
    • 0034887216 scopus 로고    scopus 로고
    • High factor VIII levels contribute to the thrombotic risk in families with factor v Leiden
    • Lensen R, Bertina RM, Vandenbroucke JP, Rosendaal FR. High factor VIII levels contribute to the thrombotic risk in families with factor V Leiden. Br J Haematol 2001;114:380-386.
    • (2001) Br J Haematol , vol.114 , pp. 380-386
    • Lensen, R.1    Bertina, R.M.2    Vandenbroucke, J.P.3    Rosendaal, F.R.4
  • 124
    • 37549053666 scopus 로고    scopus 로고
    • Association between inherited thrombophilic abnormalities and central venous catheter thrombosis in patients with cancer: A meta-analysis
    • Dentali F, Gianni M, Agnelli G, Ageno W. Association between inherited thrombophilic abnormalities and central venous catheter thrombosis in patients with cancer: a meta-analysis. J Thromb Haemost 2008;6:70-75.
    • (2008) J Thromb Haemost , vol.6 , pp. 70-75
    • Dentali, F.1    Gianni, M.2    Agnelli, G.3    Ageno, W.4
  • 125
    • 77952171390 scopus 로고    scopus 로고
    • Acquired and inherited risk factors for developing venous thromboembolism in cancer patients receiving adjuvant chemotherapy: A prospective trial
    • Mandala M, Barni S, Prins M, et al. Acquired and inherited risk factors for developing venous thromboembolism in cancer patients receiving adjuvant chemotherapy: a prospective trial. Ann Oncol 2010;21:871-876.
    • (2010) Ann Oncol , vol.21 , pp. 871-876
    • Mandala, M.1    Barni, S.2    Prins, M.3
  • 127
    • 2342437469 scopus 로고    scopus 로고
    • Factor v Leiden and G20210A prothrombin mutation and the risk of subclavian vein thrombosis in patients with breast cancer and a central venous catheter
    • Mandala M, Curigliano G, Bucciarelli P, et al. Factor V Leiden and G20210A prothrombin mutation and the risk of subclavian vein thrombosis in patients with breast cancer and a central venous catheter. Ann Oncol 2004;15:590-593.
    • (2004) Ann Oncol , vol.15 , pp. 590-593
    • Mandala, M.1    Curigliano, G.2    Bucciarelli, P.3
  • 128
    • 0035004060 scopus 로고    scopus 로고
    • The risk of pregnancy-related venous thromboembolism in women who are homozygous for factor v Leiden
    • Middeldorp S, Libourel EJ, Hamulyak K, Van der Meer J, Büller HR. The risk of pregnancy-related venous thromboembolism in women who are homozygous for factor V Leiden. Br J Haematol 2001;113:553-555.
    • (2001) Br J Haematol , vol.113 , pp. 553-555
    • Middeldorp, S.1    Libourel, E.J.2    Hamulyak, K.3    Van Der Meer, J.4    Büller, H.R.5
  • 129
    • 39549113854 scopus 로고    scopus 로고
    • The risk of first venous thromboembolism during pregnancy and puerperium in double heterozy-gotes for factor v Leiden and prothrombin G20210A
    • Martinelli I, Battaglioli T, De Stefano V, et al. The risk of first venous thromboembolism during pregnancy and puerperium in double heterozy-gotes for factor V Leiden and prothrombin G20210A. J Thromb Haemost 2008;6:494-498.
    • (2008) J Thromb Haemost , vol.6 , pp. 494-498
    • Martinelli, I.1    Battaglioli, T.2    De Stefano, V.3
  • 130
    • 0034585516 scopus 로고    scopus 로고
    • Pregnancy-associated risk for venous thromboembolism and pregnancy outcome in women homozygous for factor v Leiden
    • Pabinger I, Nemes L, Rintelen C, et al. Pregnancy-associated risk for venous thromboembolism and pregnancy outcome in women homozygous for factor V Leiden. Hematol J 2000;1:37-41.
    • (2000) Hematol J , vol.1 , pp. 37-41
    • Pabinger, I.1    Nemes, L.2    Rintelen, C.3
  • 132
    • 30644468836 scopus 로고    scopus 로고
    • Does use of hormonal contraceptives among women with thrombogenic mutations increase their risk of venous thromboembolism? A systematic review
    • Mohllajee AP, Curtis KM, Martins SL, Peterson HB. Does use of hormonal contraceptives among women with thrombogenic mutations increase their risk of venous thromboembolism? A systematic review. Contraception 2006;73:166-178.
    • (2006) Contraception , vol.73 , pp. 166-178
    • Mohllajee, A.P.1    Curtis, K.M.2    Martins, S.L.3    Peterson, H.B.4
  • 133
    • 0034627887 scopus 로고    scopus 로고
    • Higher risk of venous thrombosis during early use of oral contraceptives in women with inherited clotting defects
    • Bloemenkamp KW, Rosendaal FR, Helmerhorst FM, Vandenbroucke JP. Higher risk of venous thrombosis during early use of oral contraceptives in women with inherited clotting defects. Arch Intern Med 2000;160:49-52.
    • (2000) Arch Intern Med , vol.160 , pp. 49-52
    • Bloemenkamp, K.W.1    Rosendaal, F.R.2    Helmerhorst, F.M.3    Vandenbroucke, J.P.4
  • 134
    • 0035806996 scopus 로고    scopus 로고
    • A prospective study of asymptomatic carriers of the factor v Leiden mutation to determine the incidence of venous thromboembolism
    • Middeldorp S, Meinardi JR, Koopman MM, et al. A prospective study of asymptomatic carriers of the factor V Leiden mutation to determine the incidence of venous thromboembolism. Ann Intern Med 2001;135:322-327.
    • (2001) Ann Intern Med , vol.135 , pp. 322-327
    • Middeldorp, S.1    Meinardi, J.R.2    Koopman, M.M.3
  • 135
    • 4344665187 scopus 로고    scopus 로고
    • Long term use of oral contraceptives without thrombosis in patients with FV Leiden polymorphism: A study of 37 patients (2 homozygous and 35 heterozygous)
    • Girolami A, Tormene D, Gavasso S, Bertolo C, Girolami B. Long term use of oral contraceptives without thrombosis in patients with FV Leiden polymorphism: a study of 37 patients (2 homozygous and 35 heterozygous). J Thromb Thrombolysis 2004;17:145-149.
    • (2004) J Thromb Thrombolysis , vol.17 , pp. 145-149
    • Girolami, A.1    Tormene, D.2    Gavasso, S.3    Bertolo, C.4    Girolami, B.5
  • 136
    • 0034595197 scopus 로고    scopus 로고
    • Postmenopausal hormone therapy increases risk for venous thromboembolic disease
    • The Heart and Estrogen/progestin Replacement Study
    • Grady D, Wenger NK, Herrington D, et al. Postmenopausal hormone therapy increases risk for venous thromboembolic disease. The Heart and Estrogen/progestin Replacement Study. Ann Intern Med 2000;132:689-696.
    • (2000) Ann Intern Med , vol.132 , pp. 689-696
    • Grady, D.1    Wenger, N.K.2    Herrington, D.3
  • 137
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
    • Rossouw JE, Anderson GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA 2002;288:321-333.
    • (2002) JAMA , vol.288 , pp. 321-333
    • Rossouw, J.E.1    Anderson, G.L.2    Prentice, R.L.3
  • 138
    • 33847116637 scopus 로고    scopus 로고
    • Hormone therapy and venous thromboembolism among postmenopausal women: Impact of the route of estrogen administration and progestogens: The ESTHER study
    • Canonico M, Oger E, Plu-Bureau G, et al. Hormone therapy and venous thromboembolism among postmenopausal women: impact of the route of estrogen administration and progestogens: the ESTHER study. Circulation 2007;115:840-845.
    • (2007) Circulation , vol.115 , pp. 840-845
    • Canonico, M.1    Oger, E.2    Plu-Bureau, G.3
  • 139
    • 44849131373 scopus 로고    scopus 로고
    • Hormone replacement therapy and risk of venous thromboembolism in postmenopausal women: Systematic review and meta-analysis
    • Canonico M, Plu-Bureau G, Lowe GD, Scarabin PY. Hormone replacement therapy and risk of venous thromboembolism in postmenopausal women: systematic review and meta-analysis. BMJ 2008;336:1227-1231.
    • (2008) BMJ , vol.336 , pp. 1227-1231
    • Canonico, M.1    Plu-Bureau, G.2    Lowe, G.D.3    Scarabin, P.Y.4
  • 140
    • 77953573349 scopus 로고    scopus 로고
    • Hormone replacement therapy and the risk of venous thromboembolism: A population-based study
    • Renoux C, Dell'Aniello S, Suissa S. Hormone replacement therapy and the risk of venous thromboembolism: a population-based study. J Thromb Haemost 2010;8:979-986.
    • (2010) J Thromb Haemost , vol.8 , pp. 979-986
    • Renoux, C.1    Dell'Aniello, S.2    Suissa, S.3
  • 141
    • 33644876850 scopus 로고    scopus 로고
    • Prothrombotic mutations, hormone therapy, and venous thromboembolism among postmenopausal women: Impact of the route of estrogen administration
    • Straczek C, Oger E, Yon de Jonage-Canonico MB, et al. Prothrombotic mutations, hormone therapy, and venous thromboembolism among postmenopausal women: impact of the route of estrogen administration. Circulation 2005;112:3495-3500.
    • (2005) Circulation , vol.112 , pp. 3495-3500
    • Straczek, C.1    Oger, E.2    Yon De Jonage-Canonico, M.B.3
  • 142
    • 0141904693 scopus 로고    scopus 로고
    • Inherited and acquired risk factors for venous thromboembolic disease among women taking tamoxifen to prevent breast cancer
    • Duggan C, Marriott K, Edwards R, Cuzick J. Inherited and acquired risk factors for venous thromboembolic disease among women taking tamoxifen to prevent breast cancer. J Clin Oncol 2003;21:3588-3593.
    • (2003) J Clin Oncol , vol.21 , pp. 3588-3593
    • Duggan, C.1    Marriott, K.2    Edwards, R.3    Cuzick, J.4
  • 143
    • 33745776681 scopus 로고    scopus 로고
    • Effect of factor v Leiden and prothrombin G20210->A mutations on thromboembolic risk in the national surgical adjuvant breast and bowel project breast cancer prevention trial
    • Abramson N, Costantino JP, Garber JE, Berliner N, Wickerham DL, Wolmark N. Effect of factor V Leiden and prothrombin G20210->A mutations on thromboembolic risk in the national surgical adjuvant breast and bowel project breast cancer prevention trial. J Natl Cancer Inst 2006; 98:904-910.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 904-910
    • Abramson, N.1    Costantino, J.P.2    Garber, J.E.3    Berliner, N.4    Wickerham, D.L.5    Wolmark, N.6
  • 144
    • 77954730914 scopus 로고    scopus 로고
    • Factor v Leiden mutation and thromboembolism risk in women receiving adjuvant tamoxifen for breast cancer
    • Garber JE, Halabi S, Tolaney SM, et al. Factor V Leiden mutation and thromboembolism risk in women receiving adjuvant tamoxifen for breast cancer. J Natl Cancer Inst 2010;102:942-949.
    • (2010) J Natl Cancer Inst , vol.102 , pp. 942-949
    • Garber, J.E.1    Halabi, S.2    Tolaney, S.M.3
  • 145
    • 0030978253 scopus 로고    scopus 로고
    • Age-specific incidence rates of venous thromboembolism among heterozygous carriers of factor v Leiden mutation
    • Ridker PM, Glynn RJ, Miletich JP, Goldhaber SZ, Stampfer MJ, Hennekens CH. Age-specific incidence rates of venous thromboembolism among heterozygous carriers of factor V Leiden mutation. Ann Intern Med 1997; 126:528-531.
    • (1997) Ann Intern Med , vol.126 , pp. 528-531
    • Ridker, P.M.1    Glynn, R.J.2    Miletich, J.P.3    Goldhaber, S.Z.4    Mj-Hennekens Ch, S.5
  • 146
    • 0032951055 scopus 로고    scopus 로고
    • APC-resistance is a risk factor for postoperative thromboembolism in elective replacement of the hip or knee-a prospective study
    • Lindahl TL, Lundahl TH, Nilsson L, Andersson CA. APC-resistance is a risk factor for postoperative thromboembolism in elective replacement of the hip or knee-a prospective study. Thromb Haemost 1999;81:18-21.
    • (1999) Thromb Haemost , vol.81 , pp. 18-21
    • Lindahl, T.L.1    Lundahl, T.H.2    Nilsson, L.3    Andersson, C.A.4
  • 147
    • 33947502255 scopus 로고    scopus 로고
    • High frequency of factor v Leiden in surgical patients with symptomatic venous thromboembolism despite prophylaxis
    • Baba-Ahmed M, Le Gal G, Couturaud F, Lacut K, Oger E, Leroyer C. High frequency of factor V Leiden in surgical patients with symptomatic venous thromboembolism despite prophylaxis. Thromb Haemost 2007;97:171-175.
    • (2007) Thromb Haemost , vol.97 , pp. 171-175
    • Baba-Ahmed, M.1    Le Gal, G.2    Couturaud, F.3    Lacut, K.4    Oger, E.5    Leroyer, C.6
  • 148
    • 17144418105 scopus 로고    scopus 로고
    • A single-centre prospective study of clinical and haemostatic risk factors for venous thromboembolism following lower limb arthroplasty
    • Joseph JE, Low J, Courtenay B, Neil MJ, McGrath M, Ma D. A single-centre prospective study of clinical and haemostatic risk factors for venous thromboembolism following lower limb arthroplasty. Br J Haematol 2005; 129:87-92.
    • (2005) Br J Haematol , vol.129 , pp. 87-92
    • Joseph, J.E.1    Low, J.2    Courtenay, B.3    Neil, M.J.4    McGrath, M.5    Ma, D.6
  • 149
    • 0032520087 scopus 로고    scopus 로고
    • Relation of factor v Leiden genotype to risk for acute deep venous thrombosis after joint replacement surgery
    • Ryan DH, Crowther MA, Ginsberg JS, Francis CW. Relation of factor V Leiden genotype to risk for acute deep venous thrombosis after joint replacement surgery. Ann Intern Med 1998;128:270-276.
    • (1998) Ann Intern Med , vol.128 , pp. 270-276
    • Ryan, D.H.1    Crowther, M.A.2    Ginsberg, J.S.3    Francis, C.W.4
  • 150
    • 0031976477 scopus 로고    scopus 로고
    • Factor v Leiden is not a risk factor for arterial vascular disease in the elderly: Results from the Cardiovascular Health Study
    • Cushman M, Rosendaal FR, Psaty BM, et al. Factor V Leiden is not a risk factor for arterial vascular disease in the elderly: results from the Cardiovascular Health Study. Thromb Haemost 1998;79:912-915.
    • (1998) Thromb Haemost , vol.79 , pp. 912-915
    • Cushman, M.1    Rosendaal, F.R.2    Psaty, B.M.3
  • 151
    • 41849146788 scopus 로고    scopus 로고
    • Are patients with thrombophilia and previous venous thromboembolism at higher risk to arterial thrombosis?
    • Linnemann B, Schindewolf M, Zgouras D, Erbe M, Jarosch-Preusche M, Lindhoff-Last E. Are patients with thrombophilia and previous venous thromboembolism at higher risk to arterial thrombosis? Thromb Res 2008; 121:743-750.
    • (2008) Thromb Res , vol.121 , pp. 743-750
    • Linnemann, B.1    Schindewolf, M.2    Zgouras, D.3    Erbe, M.4    Jarosch-Preusche, M.5    Lindhoff-Last, E.6
  • 152
    • 0344196959 scopus 로고    scopus 로고
    • Association between factor v Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: A meta-analysis of published studies
    • Kim RJ, Becker RC. Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: a meta-analysis of published studies. Am Heart J 2003;146:948-957.
    • (2003) Am Heart J , vol.146 , pp. 948-957
    • Kim, R.J.1    Becker, R.C.2
  • 153
    • 33344478392 scopus 로고    scopus 로고
    • Seven haemostatic gene polymorphisms in coronary disease: Meta-analysis of 66,155 cases and 91,307 controls
    • Ye Z, Liu EH, Higgins JP, et al. Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66,155 cases and 91,307 controls. Lancet 2006;367:651-658.
    • (2006) Lancet , vol.367 , pp. 651-658
    • Ye, Z.1    Liu, E.H.2    Higgins, J.P.3
  • 154
    • 0030984288 scopus 로고    scopus 로고
    • Factor v Leiden (resistance to activated protein C) increases the risk of myocardial infarction in young women
    • Rosendaal FR, Siscovick DS, Schwartz SM, et al. Factor V Leiden (resistance to activated protein C) increases the risk of myocardial infarction in young women. Blood 1997;89:2817-2821.
    • (1997) Blood , vol.89 , pp. 2817-2821
    • Rosendaal, F.R.1    Siscovick, D.S.2    Schwartz, S.M.3
  • 155
    • 77952680092 scopus 로고    scopus 로고
    • Fine particulate: It matters
    • Mannucci PM. Fine particulate: it matters. J Thromb Haemost 2010;8:659-661.
    • (2010) J Thromb Haemost , vol.8 , pp. 659-661
    • Mannucci, P.M.1
  • 156
    • 0032562254 scopus 로고    scopus 로고
    • Interaction of coagulation defects and cardiovascular risk factors: Increased risk of myo-cardial infarction associated with factor v Leiden or prothrombin 20210A
    • Doggen CJ, Cats VM, Bertina RM, Rosendaal FR. Interaction of coagulation defects and cardiovascular risk factors: increased risk of myo-cardial infarction associated with factor V Leiden or prothrombin 20210A. Circulation 1998;97:1037-1041.
    • (1998) Circulation , vol.97 , pp. 1037-1041
    • Doggen, C.J.1    Cats, V.M.2    Bertina, R.M.3    Rosendaal, F.R.4
  • 157
    • 0033121115 scopus 로고    scopus 로고
    • Synergistic effects of prothrombotic polymorphisms and atherogenic factors on the risk of myocardial infarction in young males
    • Inbal A, Freimark D, Modan B, et al. Synergistic effects of prothrombotic polymorphisms and atherogenic factors on the risk of myocardial infarction in young males. Blood 1999;93:2186-2190.
    • (1999) Blood , vol.93 , pp. 2186-2190
    • Inbal, A.1    Freimark, D.2    Modan, B.3
  • 158
    • 22044438499 scopus 로고    scopus 로고
    • Matched case-control study on factor v Leiden and the prothrombin G20210A mutation in patients with ischemic stroke/transient ischemic attack up to the age of 60 years
    • Lalouschek W, Schillinger M, Hsieh K, et al. Matched case-control study on factor V Leiden and the prothrombin G20210A mutation in patients with ischemic stroke/transient ischemic attack up to the age of 60 years. Stroke 2005;36:1405-1409.
    • (2005) Stroke , vol.36 , pp. 1405-1409
    • Lalouschek, W.1    Schillinger, M.2    Hsieh, K.3
  • 159
    • 23944463016 scopus 로고    scopus 로고
    • Thrombophilic risk factors in patients with severe carotid atherosclerosis
    • Marcucci R, Sofi F, Fedi S, et al. Thrombophilic risk factors in patients with severe carotid atherosclerosis. J Thromb Haemost 2005;3:502-507.
    • (2005) J Thromb Haemost , vol.3 , pp. 502-507
    • Marcucci, R.1    Sofi, F.2    Fedi, S.3
  • 160
    • 0033002257 scopus 로고    scopus 로고
    • Inherited prothrombotic conditions and premature ischemic stroke: Sex difference in the association with factor v Leiden
    • Margaglione M, D'Andrea G, Giuliani N, et al. Inherited prothrombotic conditions and premature ischemic stroke: sex difference in the association with factor V Leiden. Arterioscler Thromb Vasc Biol 1999;19:1751-1756.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1751-1756
    • Margaglione, M.1    D'Andrea, G.2    Giuliani, N.3
  • 161
    • 2442598974 scopus 로고    scopus 로고
    • Factor v Leiden and prothrombin G20210A mutations in young adults with cryptogenic ischemic stroke
    • Aznar J, Mira Y, Vayá A, et al. Factor V Leiden and prothrombin G20210A mutations in young adults with cryptogenic ischemic stroke. Thromb Hae-most 2004;91:1031-1034.
    • (2004) Thromb Hae-most , vol.91 , pp. 1031-1034
    • Aznar, J.1    Mira, Y.2    Vayá, A.3
  • 163
    • 33745742732 scopus 로고    scopus 로고
    • Oral contraceptive use, thrombophilia and their interaction in young women with ischemic stroke
    • Martinelli I, Battaglioli T, Burgo I, Di Domenico S, Mannucci PM. Oral contraceptive use, thrombophilia and their interaction in young women with ischemic stroke. Haematologica 2006;91:844-847.
    • (2006) Haematologica , vol.91 , pp. 844-847
    • Martinelli, I.1    Battaglioli, T.2    Burgo, I.3    Di Domenico, S.4    Mannucci, P.M.5
  • 164
    • 60849115859 scopus 로고    scopus 로고
    • Ischaemic stroke patients with heterozygous factor v Leiden present with multiple brain infarctions and widespread atherothrombotic disease
    • Haapaniemi E, Helenius J, Jakovljević D, et al. Ischaemic stroke patients with heterozygous factor V Leiden present with multiple brain infarctions and widespread atherothrombotic disease. Thromb Haemost 2009;101: 145-150.
    • (2009) Thromb Haemost , vol.101 , pp. 145-150
    • Haapaniemi, E.1    Helenius, J.2    Jakovljević, D.3
  • 165
    • 0038057466 scopus 로고    scopus 로고
    • Factor v Leiden and prothrombin gene mutation may predispose to paradoxical embolism in subjects with patent foramen ovale
    • Karttunen V, Hiltunen L, Rasi V, Vahtera E, Hillbom M. Factor V Leiden and prothrombin gene mutation may predispose to paradoxical embolism in subjects with patent foramen ovale. Blood Coagul Fibrinolysis 2003;14: 261-268.
    • (2003) Blood Coagul Fibrinolysis , vol.14 , pp. 261-268
    • Karttunen, V.1    Hiltunen, L.2    Rasi, V.3    Vahtera, E.4    Hillbom, M.5
  • 166
    • 66149163104 scopus 로고    scopus 로고
    • Do common prothrombotic mutations influence the risk of cerebral ischaemia in patients with patent foramen ovale? Systematic review and meta-analysis
    • Pezzini A, Grassi M, Zotto ED, et al. Do common prothrombotic mutations influence the risk of cerebral ischaemia in patients with patent foramen ovale? Systematic review and meta-analysis. Thromb Haemost 2009;101: 813-817.
    • (2009) Thromb Haemost , vol.101 , pp. 813-817
    • Pezzini, A.1    Grassi, M.2    Zotto, E.D.3
  • 167
    • 29244489063 scopus 로고    scopus 로고
    • Expression of the normal factor v allele modulates the APC resistance phenotype in heterozygous carriers of the factor v Leiden mutation
    • Brugge JM, Simioni P, Bernardi F, et al. Expression of the normal factor V allele modulates the APC resistance phenotype in heterozygous carriers of the factor V Leiden mutation. J Thromb Haemost 2005;3: 2695-2702.
    • (2005) J Thromb Haemost , vol.3 , pp. 2695-2702
    • Brugge, J.M.1    Simioni, P.2    Bernardi, F.3
  • 168
    • 27144463464 scopus 로고    scopus 로고
    • An underestimated combination of opposites resulting in enhanced thrombotic tendency
    • Simioni P, Castoldi E, Lunghi B, Tormene D, Rosing J, Bernardi F. An underestimated combination of opposites resulting in enhanced thrombotic tendency. Blood 2005;106:2363-2365.
    • (2005) Blood , vol.106 , pp. 2363-2365
    • Simioni, P.1    Castoldi, E.2    Lunghi, B.3    Tormene, D.4    Rosing, J.5    Bernardi, F.6
  • 169
    • 20444489975 scopus 로고    scopus 로고
    • Double heterozygosity for factor v Leiden and factor v Cambridge mutations associated with low levels of activated protein C resistance in a Spanish thrombophilic family
    • Santamaría A, Soria JM, Tirado I, et al. Double heterozygosity for factor V Leiden and factor V Cambridge mutations associated with low levels of activated protein C resistance in a Spanish thrombophilic family. Thromb Haemost 2005;93:1193-1195.
    • (2005) Thromb Haemost , vol.93 , pp. 1193-1195
    • Santamaría, A.1    Soria, J.M.2    Tirado, I.3
  • 170
    • 0142246498 scopus 로고    scopus 로고
    • Two novel factor v null mutations associated with activated protein C resistance phenotype/genotype discrepancy
    • Dargaud Y, Trzeciak MC, Meunier S, et al. Two novel factor V null mutations associated with activated protein C resistance phenotype/genotype discrepancy. Br J Haematol 2003;123:342-345.
    • (2003) Br J Haematol , vol.123 , pp. 342-345
    • Dargaud, Y.1    Trzeciak, M.C.2    Meunier, S.3
  • 171
    • 0034127421 scopus 로고    scopus 로고
    • The HR2 haplotype of factor V: Effects on factor v levels, normalized activated protein C sensitivity ratios and the risk of venous thrombosis
    • De Visser MC, Guasch JF, Kamphuisen PW, Vos HL, Rosendaal FR, Bertina RM. The HR2 haplotype of factor V: effects on factor V levels, normalized activated protein C sensitivity ratios and the risk of venous thrombosis. Thromb Haemost 2000;83:577-582.
    • (2000) Thromb Haemost , vol.83 , pp. 577-582
    • De Visser, M.C.1    Guasch, J.F.2    Kamphuisen, P.W.3    Vos, H.L.4    Rosendaal, F.R.5    Bertina, R.M.6
  • 172
    • 0033230321 scopus 로고    scopus 로고
    • Coinheritance of the HR2 haplotype in the factor v gene confers an increased risk of venous thromboembolism to carriers of factor v R506Q (factor v Leiden)
    • Faioni EM, Franchi F, Bucciarelli P, et al. Coinheritance of the HR2 haplotype in the factor V gene confers an increased risk of venous thromboembolism to carriers of factor V R506Q (factor V Leiden). Blood 1999;94:3062-3066.
    • (1999) Blood , vol.94 , pp. 3062-3066
    • Faioni, E.M.1    Franchi, F.2    Bucciarelli, P.3
  • 173
    • 0032520041 scopus 로고    scopus 로고
    • Factor v Cambridge: A new mutation (Arg306->Thr) associated with resistance to activated protein C
    • Williamson D, Brown K, Luddington R, Baglin C, Baglin T. Factor V Cambridge: a new mutation (Arg306->Thr) associated with resistance to activated protein C. Blood 1998;91:1140-1144.
    • (1998) Blood , vol.91 , pp. 1140-1144
    • Williamson, D.1    Brown, K.2    Luddington, R.3    Baglin, C.4    Baglin, T.5
  • 174
    • 0032520034 scopus 로고    scopus 로고
    • A novel mutation of Arg306 of factor v gene in Hong Kong Chinese
    • Chan WP, Lee CK, Kwong YL, Lam CK, Liang R. A novel mutation of Arg306 of factor V gene in Hong Kong Chinese. Blood 1998;91:1135-1139.
    • (1998) Blood , vol.91 , pp. 1135-1139
    • Chan, W.P.1    Lee, C.K.2    Kwong, Y.L.3    Lam, C.K.4    Liang, R.5
  • 175
    • 0032189436 scopus 로고    scopus 로고
    • Clinical significance of Arg306 mutations of factor V gene [7]
    • Liang R, Lee CK, Wat MS, Kwong YL, Lam CK, Liu HW. Clinical significance of Arg306 mutations of factor V gene. Blood 1998;92:2599-2600. (Pubitemid 28453010)
    • (1998) Blood , vol.92 , Issue.7 , pp. 2599-2600
    • Liang, R.1    Lee, C.K.2    Wat, M.S.3    Kwong, Y.L.4    Lam, C.K.5    Liu, H.W.6
  • 176
    • 1942425200 scopus 로고    scopus 로고
    • Functional characterization of factor V-Ile359Thr: A novel mutation associated with thrombosis
    • Steen M, Norstrøm EA, Tholander AL, et al. Functional characterization of factor V-Ile359Thr: a novel mutation associated with thrombosis. Blood 2004;103:3381-3387.
    • (2004) Blood , vol.103 , pp. 3381-3387
    • Steen, M.1    Norstrøm, E.A.2    Tholander, A.L.3
  • 177
    • 0038489332 scopus 로고    scopus 로고
    • A FV multiallelic marker detects genetic components of APC resistance contributing to venous thromboembolism in FV Leiden carriers
    • Mingozzi F, Legnani C, Lunghi B, et al. A FV multiallelic marker detects genetic components of APC resistance contributing to venous thromboembolism in FV Leiden carriers. Thromb Haemost 2003;89:983-989.
    • (2003) Thromb Haemost , vol.89 , pp. 983-989
    • Mingozzi, F.1    Legnani, C.2    Lunghi, B.3
  • 178
    • 25144466083 scopus 로고    scopus 로고
    • HR2 haplotype in Arab population and patients with venous thrombosis inKuwait
    • Jadaon MM, Dashti AA. HR2 haplotype in Arab population and patients with venous thrombosis inKuwait. J Thromb Haemost 2005;3:1467-1471.
    • (2005) J Thromb Haemost , vol.3 , pp. 1467-1471
    • Jadaon, M.M.1    Dashti, A.A.2
  • 179
    • 0033972844 scopus 로고    scopus 로고
    • The factor v R2 allele: Risk of venous thromboembolism, factor v levels and resistance to activated protein C
    • Luddington R, Jackson A, Pannerselvam S, Brown K, Baglin T. The factor V R2 allele: risk of venous thromboembolism, factor V levels and resistance to activated protein C. Thromb Haemost 2000;83:204-208.
    • (2000) Thromb Haemost , vol.83 , pp. 204-208
    • Luddington, R.1    Jackson, A.2    Pannerselvam, S.3    Brown, K.4    Baglin, T.5
  • 180
    • 9144251852 scopus 로고    scopus 로고
    • Prevalence of factor v Leiden, factor v Cambridge, factor II G20210A and methylenetetrahydro-folate reductase C677T mutations in healthy and thrombophilic Serbian populations
    • Djordjevic V, Rakicevic LJ, Mikovic D, et al. Prevalence of factor V Leiden, factor V Cambridge, factor II G20210A and methylenetetrahydro-folate reductase C677T mutations in healthy and thrombophilic Serbian populations. Acta Haematol 2004;112:227-229.
    • (2004) Acta Haematol , vol.112 , pp. 227-229
    • Djordjevic, V.1    Rakicevic, L.J.2    Mikovic, D.3
  • 181
    • 0242329725 scopus 로고    scopus 로고
    • Factor v I359T: A novel mutation associated with thrombosis and resistance to activated protein C
    • Mumford AD, McVey JH, Morse CV, et al. Factor V I359T: a novel mutation associated with thrombosis and resistance to activated protein C. Br J Haematol 2003;123:496-501.
    • (2003) Br J Haematol , vol.123 , pp. 496-501
    • Mumford, A.D.1    McVey, J.H.2    Morse, C.V.3
  • 182
    • 0031985328 scopus 로고    scopus 로고
    • The incidence of venous thromboembolism in family members of patients with factor v Leiden mutation and venous thrombosis
    • Middeldorp S, Henkens CM, Koopman MM, et al. The incidence of venous thromboembolism in family members of patients with factor V Leiden mutation and venous thrombosis. Ann Intern Med 1998;128:15-20.
    • (1998) Ann Intern Med , vol.128 , pp. 15-20
    • Middeldorp, S.1    Henkens, C.M.2    Koopman, M.M.3
  • 183
    • 0000662461 scopus 로고    scopus 로고
    • Incidence of venous thromboembolism in families with inherited thrombophilia
    • Simioni P, Sanson BJ, Prandoni P, et al. Incidence of venous thromboembolism in families with inherited thrombophilia. Thromb Haemost 1999; 81:198-202.
    • (1999) Thromb Haemost , vol.81 , pp. 198-202
    • Simioni, P.1    Sanson, B.J.2    Prandoni, P.3
  • 184
    • 0037085791 scopus 로고    scopus 로고
    • Incidence of venous thromboembolism in asymptomatic family members who are carriers of factor v Leiden: A prospective cohort study
    • Simioni P, Tormene D, Prandoni P, et al. Incidence of venous thromboembolism in asymptomatic family members who are carriers of factor V Leiden: a prospective cohort study. Blood 2002;99:1938-1942.
    • (2002) Blood , vol.99 , pp. 1938-1942
    • Simioni, P.1    Tormene, D.2    Prandoni, P.3
  • 185
    • 23944444384 scopus 로고    scopus 로고
    • Risk of a first venous thrombotic event in carriers of a familial thrombophilic defect. The European Prospective Cohort on Thrombophilia (EPCOT)
    • Vossen CY, Conard J, Fontcuberta J, et al. Risk of a first venous thrombotic event in carriers of a familial thrombophilic defect. The European Prospective Cohort on Thrombophilia (EPCOT). J Thromb Haemost 2005;3:459-464.
    • (2005) J Thromb Haemost , vol.3 , pp. 459-464
    • Vossen, C.Y.1    Conard, J.2    Fontcuberta, J.3
  • 186
    • 0029850530 scopus 로고    scopus 로고
    • A common genetic variation in the 3 '-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis
    • Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3 '-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996;88:3698-3703.
    • (1996) Blood , vol.88 , pp. 3698-3703
    • Poort, S.R.1    Rosendaal, F.R.2    Reitsma, P.H.3    Bertina, R.M.4
  • 187
    • 77249160223 scopus 로고    scopus 로고
    • Inherited thrombophilia: Implications for prevention and treatment of venous thromboembolism
    • Coppola A, Tufano A, Cerbone AM, Di Minno G. Inherited thrombophilia: implications for prevention and treatment of venous thromboembolism. Semin Thromb Hemost 2009;35:683-694.
    • (2009) Semin Thromb Hemost , vol.35 , pp. 683-694
    • Coppola, A.1    Tufano, A.2    Cerbone, A.M.3    Di Minno, G.4
  • 188
    • 33947251140 scopus 로고    scopus 로고
    • No association between the common MTHFR 677C->T polymorphism and venous thrombosis: Results from the MEGA study
    • Bezemer ID, Doggen CJ, Vos HL, Rosendaal FR. No association between the common MTHFR 677C->T polymorphism and venous thrombosis: results from the MEGA study. Arch Intern Med 2007;167:497-501.
    • (2007) Arch Intern Med , vol.167 , pp. 497-501
    • Bezemer, I.D.1    Doggen, C.J.2    Vos, H.L.3    Rosendaal, F.R.4
  • 189
    • 0033557951 scopus 로고    scopus 로고
    • A reduced sensitivity for activated protein C in the absence of factor v Leiden increases the risk of venous thrombosis
    • De Visser MC, Rosendaal FR, Bertina RM. A reduced sensitivity for activated protein C in the absence of factor V Leiden increases the risk of venous thrombosis. Blood 1999;93:1271-1276.
    • (1999) Blood , vol.93 , pp. 1271-1276
    • De Visser, M.C.1    Rosendaal, F.R.2    Bertina, R.M.3
  • 190
    • 0033586755 scopus 로고    scopus 로고
    • Activated protein C resistance and factor v Leiden mutation are independent risk factors for venous thromboembolism
    • Rodeghiero F, Tosetto A. Activated protein C resistance and factor V Leiden mutation are independent risk factors for venous thromboembolism. Ann Intern Med 1999;130:643-650.
    • (1999) Ann Intern Med , vol.130 , pp. 643-650
    • Rodeghiero, F.1    Tosetto, A.2
  • 191
    • 0037370733 scopus 로고    scopus 로고
    • Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: A systematic review of the literature
    • Galli M, Luciani D, Bertolini G, Barbui T. Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: a systematic review of the literature. Blood 2003;101:1827-1832.
    • (2003) Blood , vol.101 , pp. 1827-1832
    • Galli, M.1    Luciani, D.2    Bertolini, G.3    Barbui, T.4
  • 192
    • 20444480632 scopus 로고    scopus 로고
    • Elevated levels of FVIII:C within families are associated with an increased risk for venous and arterial thrombosis
    • Bank I, Libourel EJ, Middeldorp S, et al. Elevated levels of FVIII:C within families are associated with an increased risk for venous and arterial thrombosis. J Thromb Haemost 2005;3:79-84.
    • (2005) J Thromb Haemost , vol.3 , pp. 79-84
    • Bank, I.1    Libourel, E.J.2    Middeldorp, S.3
  • 193
    • 0028814316 scopus 로고
    • Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis
    • Koster T, Blann AD, Briet E, Vandenbroucke JP, Rosendaal FR. Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis. Lancet 1995;345:152-155.
    • (1995) Lancet , vol.345 , pp. 152-155
    • Koster, T.1    Blann, A.D.2    Briet, E.3    Vandenbroucke, J.P.4    Rosendaal, F.R.5
  • 194
    • 0034680013 scopus 로고    scopus 로고
    • High plasma levels of factor VIII and the risk of recurrent venous thromboembolism
    • Kyrle PA, Minar E, Hirschl M, et al. High plasma levels of factor VIII and the risk of recurrent venous thromboembolism. N Engl J Med 2000;343: 457-462.
    • (2000) N Engl J Med , vol.343 , pp. 457-462
    • Kyrle, P.A.1    Minar, E.2    Hirschl, M.3
  • 196
    • 70449472262 scopus 로고    scopus 로고
    • Coagulation factors IX through XIII and the risk of future venous thrombosis: The Longitudinal Investigation of Thromboembolism Etiology
    • Cushman M, O'Meara ES, Folsom AR, Heckbert SR. Coagulation factors IX through XIII and the risk of future venous thrombosis: the Longitudinal Investigation of Thromboembolism Etiology. Blood 2009;114:2878-2883.
    • (2009) Blood , vol.114 , pp. 2878-2883
    • Cushman, M.1    O'Meara, E.S.2    Folsom, A.R.3    Heckbert, S.R.4
  • 197
  • 198
    • 33845964945 scopus 로고    scopus 로고
    • Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: A randomized, placebo-controlled, double-blind trial
    • Den Heijer M, Willems HP, Blom HJ, et al. Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: a randomized, placebo-controlled, double-blind trial. Blood 2007;109:139-144.
    • (2007) Blood , vol.109 , pp. 139-144
    • Den Heijer, M.1    Willems, H.P.2    Blom, H.J.3
  • 199
    • 45949100970 scopus 로고    scopus 로고
    • Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians evidence-based clinical practice guidelines (8th edition)
    • DOI 10.1378/chest.08-0658
    • Kearon C, Kahn SR, Agnelli G, Goldhaber S, Raskob GE, Comerota AJ, American College of Chest Physicians. Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008;133:454S-545S. (Pubitemid 351892971)
    • (2008) Chest , vol.133 , Issue.SUPPL. 6
    • Kearon, C.1    Kahn, S.R.2    Agnelli, G.3    Goldhaber, S.4    Raskob, G.E.5    Comerota, A.J.6
  • 200
    • 0031929806 scopus 로고    scopus 로고
    • Risk of recurrent venous thromboembolism in patients with the factor v Leiden (FVR506Q) mutation: Effect of warfarin and prediction by precipitating factors
    • East Anglian Thrombophilia Study Group
    • Baglin C, Brown K, Luddington R, Baglin T. Risk of recurrent venous thromboembolism in patients with the factor V Leiden (FVR506Q) mutation: effect of warfarin and prediction by precipitating factors. East Anglian Thrombophilia Study Group. Br J Haematol 1998;100:764-768.
    • (1998) Br J Haematol , vol.100 , pp. 764-768
    • Baglin, C.1    Brown, K.2    Luddington, R.3    Baglin, T.4
  • 201
    • 0029982331 scopus 로고    scopus 로고
    • Antiphospholipid antibodies, recurrent thromboembolism, and intensity of warfarin anticoagulation
    • Prandoni P, Simioni P, Girolami A. Antiphospholipid antibodies, recurrent thromboembolism, and intensity of warfarin anticoagulation. Thromb Hae-most 1996;75:859.
    • (1996) Thromb Hae-most , vol.75 , pp. 859
    • Prandoni, P.1    Simioni, P.2    Girolami, A.3
  • 202
    • 46049090201 scopus 로고    scopus 로고
    • Prevention of venous thrombo-embolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    • Geerts WH, Bergqvist D, Pineo GF, et al. Prevention of venous thrombo-embolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008;133:381S-453S.
    • (2008) Chest , vol.133
    • Geerts, W.H.1    Bergqvist, D.2    Pineo, G.F.3
  • 203
    • 23844450754 scopus 로고    scopus 로고
    • Risk of pregnancy-associated recurrent venous thromboembolism in women with a history of venous thrombosis
    • Pabinger I, Grafenhofer H, Kaider A, et al. Risk of pregnancy-associated recurrent venous thromboembolism in women with a history of venous thrombosis. J Thromb Haemost 2005;3:949-954.
    • (2005) J Thromb Haemost , vol.3 , pp. 949-954
    • Pabinger, I.1    Grafenhofer, H.2    Kaider, A.3
  • 204
    • 33749266340 scopus 로고    scopus 로고
    • The risk of recurrent venous thromboembolism in pregnancy and puerperium without antithrombotic prophylaxis
    • De Stefano V, Martinelli I, Rossi E, et al. The risk of recurrent venous thromboembolism in pregnancy and puerperium without antithrombotic prophylaxis. Br J Haematol 2006;135:386-391.
    • (2006) Br J Haematol , vol.135 , pp. 386-391
    • De Stefano, V.1    Martinelli, I.2    Rossi, E.3
  • 205
    • 0141503825 scopus 로고    scopus 로고
    • Thromboprophylaxis improves the live birth rate in women with consecutive recurrent miscarriages and hereditary thrombophilia
    • Carp H, Dolitzky M, Inbal A. Thromboprophylaxis improves the live birth rate in women with consecutive recurrent miscarriages and hereditary thrombophilia. J Thromb Haemost 2003;1:433-438.
    • (2003) J Thromb Haemost , vol.1 , pp. 433-438
    • Carp, H.1    Dolitzky, M.2    Inbal, A.3
  • 206
    • 2342633147 scopus 로고    scopus 로고
    • Low-molecular-weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional throm-bophilic disorder
    • Gris JC, Mercier E, Quéré I, et al. Low-molecular-weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional throm-bophilic disorder. Blood 2004;103:3695-3699.
    • (2004) Blood , vol.103 , pp. 3695-3699
    • Gris, J.C.1    Mercier, E.2    Quéré, I.3
  • 207
    • 20844443510 scopus 로고    scopus 로고
    • Efficacy and safety of two doses of enoxaparin in women with thrombophilia and recurrent pregnancy loss: The LIVE-ENOX study
    • LIVE-ENOX Investigators
    • Brenner B, Hoffman R, Carp H, Dulitsky M, Younis J, LIVE-ENOX Investigators. Efficacy and safety of two doses of enoxaparin in women with thrombophilia and recurrent pregnancy loss: the LIVE-ENOX study. J Thromb Haemost 2005;3:227-229.
    • (2005) J Thromb Haemost , vol.3 , pp. 227-229
    • Brenner, B.1    Hoffman, R.2    Carp, H.3    Dulitsky, M.4    Younis, J.5
  • 208
    • 60849108621 scopus 로고    scopus 로고
    • Throm-boprophylaxis and pregnancy outcomes in asymptomatic women with inherited thrombophilias
    • Warren JE, Simonsen SE, Branch DW, Porter TF, Silver RM. Throm-boprophylaxis and pregnancy outcomes in asymptomatic women with inherited thrombophilias. Am J Obstet Gynecol 2009;200:281.e1-281.e5.
    • (2009) Am J Obstet Gynecol , vol.200
    • Warren, J.E.1    Simonsen, S.E.2    Branch, D.W.3    Porter, T.F.4    Silver, R.M.5
  • 209
    • 64849104901 scopus 로고    scopus 로고
    • Low molecular weight heparin and aspirin for recurrent pregnancy loss: Results from the randomized, controlled HepASA Trial
    • Laskin CA, Spitzer KA, Clark CA, et al. Low molecular weight heparin and aspirin for recurrent pregnancy loss: results from the randomized, controlled HepASA Trial. J Rheumatol 2009;36:279-287.
    • (2009) J Rheumatol , vol.36 , pp. 279-287
    • Laskin, C.A.1    Spitzer, K.A.2    Clark, C.A.3


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