Iron deficiency activates pro-inflammatory signaling in macrophages and foam cells via the p38 MAPK-NF-κB pathway

International Journal of Cardiology

Volumn 152, Issue 1, 2011, Pages 49-55

  Fan, Yuqi ^a,c   Wang, Jun ^b   Wei, Li ^b   He, Ben ^a   Wang, Changqian ^c   Wang, Binyao ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Shanghai Institute of Traumatology and Orthopaedics   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Atherosclerosis; Extracellular matrix metalloproteinase inducer (EMMPRIN); Iron deficiency; Matrix metalloproteinase 9 (MMP 9); Mitogen activated protein kinase (MAPK)

Indexed keywords

CD147 ANTIGEN; DEFEROXAMINE; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR RELA;

ARTICLE; ATHEROMA; ATHEROSCLEROTIC PLAQUE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FOAM CELL; HUMAN; HUMAN CELL; IRON DEFICIENCY; MACROPHAGE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ZYMOGRAPHY;

ACUTE CORONARY SYNDROME; ANTIGENS, CD147; ATHEROSCLEROSIS; CELL LINE; DEFEROXAMINE; FOAM CELLS; GENE EXPRESSION; HEMORRHAGE; HUMANS; IRON; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 9; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SIDEROPHORES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA;

EID: 78751538345     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2010.07.005     Document Type: Article

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