Differential expression of factors involved in the intrinsic and extrinsic apoptotic pathways in juvenile systemic lupus erythematosus

Lupus

Volumn 20, Issue 1, 2011, Pages 71-79

  Midgley, A ^a   Mayer, K ^a   Edwards, S W ^a   Beresford, M W ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

apoptosis; caspase; neutrophil; systemic lupus erythematosus

Indexed keywords

CASPASE; CASPASE 3; CASPASE 7; CASPASE 8 INHIBITOR; CASPASE 9; CASPASE 9 INHIBITOR; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; CYCLOHEXIMIDE; FAS ASSOCIATED DEATH DOMAIN PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 1; INHIBITOR OF APOPTOSIS PROTEIN 2; PROTEIN BID; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; X LINKED INHIBITOR OF APOPTOSIS;

APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; IMMUNOLOGICAL TOLERANCE; JUVENILE; JUVENILE ONSET SYSTEMIC LUPUS ERYTHEMATOSUS; NEUTROPHIL; ONSET AGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; WESTERN BLOTTING;

ADOLESCENT; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASES; CHILD; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; FEMALE; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; NEUTROPHILS; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RNA, MESSENGER; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 78751537310     PISSN: 09612033     EISSN: None     Source Type: Journal    
DOI: 10.1177/0961203310382128     Document Type: Article

References (26)

1. Steller H. Mechanisms and genes of cellular suicide. Science 1995 ; 267: 1445-1449.
2. Deveraux QL, Roy N., Stennicke HR, et al. IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. EMBO J 1998 ; 17: 2215-2223.
3. Thompson CB Apoptosis in the pathogenesis and treatment of disease. Science 1995 ; 267: 1456-1462.
4. Dallegri F., Ottonello L. Tissue injury in neutrophilic inflammation. Inflamm Res 1997 ; 46: 382-391.
5. Harper L. ANCA-associated vasculitis: is there a role for neutrophil apoptosis in autoimmunity? Expert Rev Clin Immunol 2006 ; 2: 237-244.
6. Midgley A., McLaren Z., Moots R., Edwards SE, Beresford MW The role of neutrophil apoptosis in Juvenile Systemic Lupus Erythematosus. Arthritis Rheum 2009 ; 60: 2390-2401.
7. Igney FH, Krammer PH Death and anti-death: tumour resistance to apoptosis. Nat Rev Cancer 2002 ; 2: 277-288.
8. Maianski NA, Maianski AN, Kuijpers TW, Roos D. Apoptosis of neutrophils. Acta Haematol 2004 ; 111: 56-66.
9. O'Neill A., Greenan MC, Doyle B., Fitzpatrick JM, Watson RW Gene profiling of in vitro and in vivo models of delayed neutrophil apoptosis: a common pathway? Biochem Soc Trans 2004 ; 32: 470-473.
10. Hasegawa T., Suzuki K., Sakamoto C., et al. Expression of the inhibitor of apoptosis (IAP) family members in human neutrophils: up-regulation of cIAP2 by granulocyte colony-stimulating factor and overexpression of cIAP2 in chronic neutrophilic leukemia. Blood 2003 ; 101: 1164-1171.
11. Scott FL, Denault JB, Riedl SJ, Shin H., Renatus M., Salvesen GS XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs. EMBO J 2005 ; 24: 645-655.
12. Hochberg MC Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1997 ; 40: 1725.
13. Whyte MK, Savill J., Meagher LC, Lee A., Haslett C. Coupling of neutrophil apoptosis to recognition by macrophages: coordinated acceleration by protein synthesis inhibitors. J Leukoc Biol 1997 ; 62: 195-202.
14. Isenberg DA, Rahman A., Allen E., et al. BILAG 2004. Development and initial validation of an updated version of the British Isles Lupus Assessment Group's disease activity index for patients with systemic lupus erythematosus. Rheumatology (Oxford) 2005 ; 44: 902-906.
15. Bengtsson AA, Sturfelt G., Gullstrand B., Truedsson L. Induction of apoptosis in monocytes and lymphocytes by serum from patients with systemic lupus erythematosus - an additional mechanism to increased autoantigen load? Clin Exp Immunol 2004 ; 135: 535-543.
16. Courtney PA, Crockard AD, Williamson K., Irvine AE, Kennedy RJ, Bell AL Increased apoptotic peripheral blood neutrophils in systemic lupus erythematosus: relations with disease activity, antibodies to double stranded DNA, and neutropenia. Ann Rheum Dis 1999 ; 58: 309-314.
17. Bijl M., Limburg PC, Kallenberg CG New insights into the pathogenesis of systemic lupus erythematosus (SLE): the role of apoptosis. Neth J Med 2001 ; 59: 66-75.
18. Srinivasula SM, Ashwell JD IAPs: what's in a name? Mol Cell 2008 ; 30: 123-135.
19. Yang YL, Li XM The IAP family: endogenous caspase inhibitors with multiple biological activities. Cell Res 2000 ; 10: 169-177.
20. Eckelman BP, Salvesen GS, Scott FL Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family. EMBO Rep 2006 ; 7: 988-994.
21. Krishnan S., Kiang JG, Fisher CU, et al. Increased caspase-3 expression and activity contribute to reduced CD3zeta expression in systemic lupus erythematosus T cells. J Immunol 2005 ; 175: 3417-3423.
22. Thornberry NA, Rano TA, Peterson EP, et al. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J Biol Chem 1997 ; 272: 17907-17911.
23. Walsh JG, Cullen SP, Sheridan C., Luthi AU, Gerner C., Martin SJ Executioner caspase-3 and caspase-7 are functionally distinct proteases. Proc Natl Acad Sci U S A 2008 ; 105: 12815-12819.
24. Schultz DR, Harrington Jr WJ Apoptosis: programmed cell death at a molecular level. Semin Arthritis Rheum 2003 ; 32: 345-369.
25. Li H., Zhu H., Xu CJ, Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998 ; 94: 491-501.
26. Bengtsson AA, Gullstrand B., Truedsson L., Sturfelt G. SLE serum induces classical caspase-dependent apoptosis independent of death receptors. Clin Immunol 2008 ; 126: 57-66.