Circulating levels of IGF1 are associated with muscle strength in middle-aged- and oldest-old women

European Journal of Endocrinology

Volumn 164, Issue 2, 2011, Pages 189-196

  Taekema, Diana G ^a,b   Ling, Carolina H Y ^a   Blauw, Gerard Jan ^a   Meskers, Carel G ^a   Westendorp, Rudi G J ^a   De Craen, Anton J M ^a   Maier, Andrea B ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RIJNSTATE HOSPITAL   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DAILY LIFE ACTIVITY; FEMALE; GENETIC ASSOCIATION; GRIP STRENGTH; HUMAN; MAJOR CLINICAL STUDY; MALE; PHYSICAL PERFORMANCE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; AGE DISTRIBUTION; AGING; FUNCTIONAL ASSESSMENT; MUSCLE FUNCTION; MUSCLE STRENGTH; PHYSICAL CAPACITY; POSTMENOPAUSE; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SEX DIFFERENCE; WALKING SPEED;

AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; CROSS-SECTIONAL STUDIES; FEMALE; HAND STRENGTH; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; LINEAR MODELS; MALE; MIDDLE AGED; MUSCLE STRENGTH; SEX FACTORS; WALKING;

EID: 78751492195     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-10-0703     Document Type: Article

References (52)

1. Fisher AL. Ofworms andwomen: sarcopenia and its role in disability and mortality. Journal of the American Geriatrics Society 2004 52 1185-1190. (doi:10.1111/j.1532-5415.2004.52320.x)
2. Ling CHY, Taekema D, de Craen AJM, Gussekloo J,Westendorp RGJ & Maier AB. Handgrip strength and mortality in the oldest old. The Leiden 85-plus Study. CMAJ: Canadian Medical Association Journal 2010 182 429-435. (doi:10.1503/cmaj.091278)
3. Taekema DG, Gussekloo J, Maier AB, Westendorp RGJ & de Craen AJM. Handgrip strength as a predictor of functional, psychological and social health. A prospective population based study among the oldest old. Age and Ageing 2010 39 331-337. (doi:10.1093/ageing/afq022)
4. Doherty TJ. Invited review: aging and sarcopenia. Journal of Applied Physiology 2003 95 1717-1727. (doi:10.1152/japplphysiol.00347.2003)
5. World Population Ageing: 1950-2050. pp 23. New York: United Nations Population Publication, 2002.
6. Sherlock M & Toogood AA. Aging and the growth hormone/insulin like growth factor-1 axis. Pituitary 2007 10 189-203. (doi:10.1007/s11102-007-0039-5) (Pubitemid 46863733)
7. Giovannini S, Marzetti E, Borst SE & Leeuwenburgh C. Modulation of GH/IGF-1 axis: potential strategies to counteract sarcopenia in older adults. Mechanisms of Ageing and Development 2008 129 593-601. (doi:10.1016/j.mad.2008. 08.001)
8. Woodhouse LJ, Mukherjee A, Shalet SM & Ezzat S. The influence of growth hormone status on physical impairments, functional limitations, and health related quality of life in adults. Endocrine Reviews 2006 26 287-317. (doi:10.1210/er.2004-0022)
9. Onder G, Liperoti R, Russo A, Soldato M, Capoluongo E, Volpato S, Cesari M, Ameglio F, Bernabei R & Landi F. Body mass index, free insulin-like growth factor I, and physical function among older adults: results from the ilSIRENTE study. American Journal of Physiology. Endocrinology and Metabolism 2006 291 E829-E834. (doi:10.1152/ajpendo.00138.2006)
10. Cappola AR, Bandeen-Roche K, Wand GS, Volpato S & Fried LP. Association of IGF-I levels with muscle strength and mobility in older women. Journal of Clinical Endocrinology and Metabolism 2001 86 4139-4146. (doi:10.1210/jc.86.9.4139)
11. Kaplan RC, McGinn AP, Pollak MN, Kuller L, Strickler HD, Rohan TE, Xue X, Kritchevsky SB, Newman AB & Psaty BM. Total insulin like growth factor 1 and insulin like growth factor binding protein levels, functional status, and mortality in older adults. Journal of the American Geriatrics Society 2008 56 652-660. (doi:10.1111/j.1532-5415.2007.01637.x) (Pubitemid 351473531)
12. Roubenoff R, Parise H, Payette HA, Abad LW, D'Agostino R, Jacques PF, Wilson PWF, Dinarello CA & Harris TB. Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study. American Journal of Medicine 2003 115 429-435. (doi:10.1016/j.amjmed.2003.05.001) (Pubitemid 37237554)
13. Papadakis MA, Grady D, Black D, Tierney MJ, Gooding GAW, Schambelan M & Grunfeld C. Growth hormone replacement in healthy older men improves body composition but not functional ability. Annals of Internal Medicine 1996 124 708-716.
14. White HK, Petrie CD, LandschulzW, MacLean D, Taylor A, Lyles K, Wei JY, Hoffman AR, Salvatori R, Ettinger MP, Morey MC, Blackman MR, Merriam GR & for the Capromorelin Study Group. Effects of an oral growth hormone secretagogue in older adults. Journal of Clinical Endocrinology and Metabolism 2009 94 1198-1206. (doi:10.1210/jc.2008-0632)
15. Sattler FR, Castaneda-Sceppa C, Binder EF, Schroeder ET, Wang Y, Bhasin S, Kawakubo M, Stewart Y, Yarasheski KE, Ulloor J, Colletti P, Roubenoff R & Azen SP. Testosterone and growth hormone improve body composition and muscle performance in older men. Journal of Clinical Endocrinology and Metabolism 2009 94 1991-2001. (doi:10.1210/jc.2008-2338)
16. Westendorp RGJ, van Heemst D, Rozing MP, Frölich M, Mooijaart SP, Blauw GJ, Beekman M, Heijmans BT, de Craen AJM, Slagboom PE & for the Leiden Longevity Study Group. Nonagenarian siblings and their offspring display lower risk of mortality and morbidity thansporadic nonagenarians: the Leiden Longevity Study. Journal of the American Geriatrics Society 2009 57 1634-1637. (doi:10.1111/j.1532-5415.2009.02381.x)
17. Bootsma-van der Wiel A, van Exel E, de Craen AJM, Gussekloo J, Lagaay AM, Knook DL & Westendorp RGJ. A high response is not essential to prevent selection bias: results from the Leiden 85-plus Study. Journal of Clinical Epidemiology 2002 55 1119-1125. (doi:10.1016/S0895-4356(02)00505-X)
18. Andreassen M, Raymond I, Hildebrandt P, Kistorp C, Rathcke C, Vestergaard H, Faber J & Østergaard Kristensen L. Associations between plasma insulin-like growth factor-I and the markers of inflammation interleukin 6, C-reactive protein and YKL-40 in an elderly background population. Inflammation Research 2010 59 503-510. (doi:10.1007/s00011-009-0154-z)
19. Lauretani F, Russo CR, Bandinelli S, Bartali B, Cavazzini C, Di Iorio A, Corsi AM, Rantanen T, Guralnik JM & Ferrucci L. Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. Journal of Applied Physiology 2003 95 1851-1860. (doi:10.1152/japplphysiol.00246.2003) (Pubitemid 37310367)
20. Abellan van Kan G, André E, Bischoff Ferrari HA, Boirie Y, Onder G, Pahor M, Ritz P, Rolland Y, Sampaio C, Studenski S, Visser M & Vellas B. Carla task force on sarcopenia: propositions for clinical trials. Journal of Nutrition, Health and Aging 2009 13 700-707. (doi:10.1007/s12603-009-0200-0)
21. Peolsson A, Hedlund R & Oberg B. Intra- and inter-tester reliability and reference values for hand strength. Journal of Rehabilitation Medicine 2001 33 36-41. (doi:10.1080/165019701300006524)
22. Luna-Heredia E, Martín-Peňa G & Ruiz-Galiana J. Handgrip dynamometry in healthy adults. Clinical Nutrition 2005 24 250-258. (doi:10.1016/j.clnu.2004.10.007)
23. Budziareck MB, Pureza Duarte RR & Barbosa-Silva MC. Reference values and determinants for handgrip strength in healthy subjects. Clinical Nutrition 2008 27 357-362. (doi:10.1016/j.clnu.2008.03.008)
24. Kempen GI, Miedema I, Ormel J & Molenaar W. The assessment of disability with the Groningen Activity Restriction Scale. Conceptual framework and psychometric properties. Social Science and Medicine 1996 43 1601-1610. (doi:10.1016/S0277-9536(96)00057-3)
25. Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, Scherr PA & Wallace RB. A short physical performance battery assessing lower extremity function: association with self reported disability and prediction of mortality and nursing home admission. Journal of Gerontology 1994 49 M85-M94. (doi:10.1093/geronj/49.2.M85)
26. Goldspink G. Loss of muscle strength during aging studied at the gene level. Rejuvenation Research 2007 10 397-405. (doi:10.1089/rej.2007.0597)
27. Ohlsson C, Mohan S, Sjögren K, Tivesten A, Isgaard J, Isaksson O, Jansson JO & Svensson J. The role of liver-derived insulin-like growth factor-I. Endocrine Reviews 2009 30 494-535. (doi:10.1210/er.2009-0010)
28. Laviola L, Natalicchio A, Perrini S & Giorgino F. Abnormalities of IGF-I signaling in the pathogenesis of diseases of the bone, brain, and fetoplacental unit in humans. American Journal of Physiology. Endocrinology and Metabolism 2008 295 E991-E999. (doi:10.1152/ajpendo.90452.2008)
29. Li M, Li C & Parkhouse WS. Age-related differences in the des IGF-I-mediated activation of Akt-1 and p70 S6K in mouse skeletal muscle. Mechanisms of Ageing and Development 2003 124 771-778. (doi:10.1016/S0047- 6374(03)00124-6) (Pubitemid 37279135)
30. Sell C, Ptasznik A, Chang CD, Swantek J, Cristofalo VJ & Baserga R. IGF-1 receptor levels and the proliferation of young and senescent human fibroblasts. Biochemical and Biophysical Research Communications 1993 194 259-265. (doi:10.1006/bbrc.1993.1813) (Pubitemid 23237929)
31. Perrini S, Laviola L, Carreira MC, Cignarelli A, Natalicchio A & Giorgino F. The GH/IGF1 axis and signaling pathways in the muscle and bone: mechanisms underlying age-related skeletal muscle wasting and osteoporosis. Journal of Endocrinology 2010 205 201-210. (doi:10.1677/JOE-09-0431)
32. Kostka T, Arsac LM, Patricot MC, Berthouze SE, Lacour JR & Bonnefoy M. Leg extensor power and dehydroepiandrosterone sulfate, insulin-like growth factor-I and testosterone in healthy active elderly people. European Journal of Applied Physiology 2000 82 83-90. (doi:10.1007/s004210050655)
33. Orsatti FL, Nahas EAP, Maesta N, Nahas-Neto J & Burini RC. Plasma hormones, muscle mass and strength in resistance-trained postmenopausal women. Maturitas 2008 59 394-404. (doi:10.1016/j.maturitas.2008.04.002)
34. Rudman D, Kutner MH, Rogers CM, Lubin MF, Fleming GA & Bain RP. Impaired growth hormone secretion in the adult population: relation to age and adiposity. Journal of Clinical Investigation 1981 67 1361-1369. (doi:10.1172/JCI110164)
35. Landin-Wilhelmsen K, Wilhelmsen L, Lappas G, Rosén T, Lindstedt G, Lundberg PA & Bengtsson BA. Serum insulin-like growth factor I in a random population sample of men and women: relation to age, sex, smoking habits, coffee consumption and physical activity, blood pressure and concentrations of plasma lipids, fibrinogen, parathyroid hormone and osteocalcin. Clinical Endocrinology 1994 41 351-357. (doi:10.1111/j.1365-2265.1994.tb02556.x) (Pubitemid 24278330)
36. Leifke E, Gorenoi V, Wichers C, Von Zur Mühlen A, Von Büren E & Brabant G. Age-related changes of serum sex hormones, insulin-like growth factor-1 and sex-hormone binding globulin levels in men: cross-sectional data from a healthy male cohort. Clinical Endocrinology 2000 53 689-695. (doi:10.1046/j.1365-2265.2000.01159.x)
37. Jakobsdóttir S, van Nieuwpoort IC, Schaap LA, van Schoor NM, Lips P & Drent ML. Serum insulin-like growth factor-I and body composition in community dwelling older people. Clinical Endocrinology 2010 73 173-180. (doi:10.1111/j.1365-2265.2009.03747.x)
38. Yamamoto H, Sohmiya M, Oka N & Kato Y. Effects of aging and sex on plasma insulin-like growth factor I (IGF-I) levels in normal adults. Acta Endocrinologica 1991 124 497-500. (doi:10.1530/acta.0.1240497)
39. Friedrich N, Krebs A, Nauck M & Wallaschofski H. Age- and gender-specific reference ranges for serum insulin-like growth factor I (IGF-I) and IGF-binding protein-3 concentrations on the Immulite 2500: results of the Study of Health in Pomerania (SHIP). Clinical Chemistry and Laboratory Medicine 2010 48 115-120. (doi:10.1515/CCLM.2010.009)
40. Baumgartner RN, Waters DL, Gallagher D, Morley JE & Garry PJ. Predictors of skeletal muscle mass in elderly men and women. Mechanisms of Ageing and Development 1999 107 123-136. (doi:10.1016/S0047-6374(98)00130-4)
41. Gläser S, Friedrich N, Ewert R, Schäper C, Krebs A, Dörr M, Völzke H, Felix SB, Nauck M, Wallaschofski H & Koch B. Association of circulating IGF-I and IGFBP-3 concentrations and exercise capacity in healthy volunteers: results of the Study of Health in Pomerania. Growth Hormone and IGF Research 2010 20 404-410. (doi:10.1016/j.ghir.2010.09.002)
42. Cappola AR, Xue QL & Fried LP. Multiple hormonal deficiencies in anabolic hormones are found in frail older women: the Women's Health and Aging Studies. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 2009 64A 243-248. (doi:10.1093/gerona/gln026)
43. Harris TB, Kiel D, Roubenoff R, Langlois J, Hannan M, Havlik R & Wilson P. Association of insulin-like growth factor-I with body composition, weight history, and past health behaviors in the very old: the Framingham Heart Study. Journal of the American Geriatrics Society 1997 45 133-139. (Pubitemid 27066520)
44. Boonen S, Lysens R, Verbeke G, Joosten E, Dejaeger E, Pelemans W, Flamaing J & Bouillon R. Relationship between age-associated endocrine deficiencies and muscle function in elderly women: a cross-sectional study. Age and Ageing 1998 27 449-454. (doi:10.1093/ageing/27.2.231)
45. Kiel DP, Puhl J, Rosen CJ, Berg K,Murphy JB & MacLean DB. Lack of an association between insulin-like growth factor-I and body composition,muscle strength, physical performance or self-reported mobility among older persons with functional limitations. Journal of the American Geriatrics Society 1998 46 822-828.
46. Short KR, Moller N, Bigelow ML, Coenen-Schimke J & Nair KS. Enhancement of muscle mitochondrial function by growth hormone. Journal of Clinical Endocrinology and Metabolism 2008 93 597-604. (doi:10.1210/jc.2007- 1814) (Pubitemid 351240836)
47. Schertzer JD, Ryall JG & Lynch GS. Systemic administration of IGF-I enhances oxidative status and reduces contraction-induced injury in skeletal muscles of mdx dystrophic mice. American Journal of Physiology. Endocrinology and Metabolism 2006 291 E499-E505. (doi:10.1152/ajpendo.00101.2006)
48. Lynch GS, Cuffe SA, Plant DR & Gregorevic P. IGF-I treatment improves the functional properties of fast- and slow-twitch skeletal muscles from dystrophic mice. Neuromuscular Disorders 2001 11 260-268. (doi:10.1016/S0960- 8966(00)00192-9)
49. Gregorevic P, Plant DR, Leeding KS, Bach LA & Lynch GS. Improved contractile function of the mdx dystrophic mouse diaphragm muscle after insulin-like growth factor-I administration. American Journal of Pathology 2002 161 2263-2272.
50. Yang S, Alnaqeeb M, Simpson H & Goldspink G. Cloning and characterization of an IGF-1 isoform expressed in skeletal muscle subjected to stretch. Journal of Muscle Research and Cell Motility 1996 17 487-495. (doi:10.1007/BF00123364) (Pubitemid 26298531)
51. Loughna PT, Mason P & Bates PC. Regulation of insulin-like growth factor 1 gene expression in skeletal muscle. Symposia of the Society for Experimental Biology 1992 46 319-330.
52. Brugts MP, Ranke MB, Hofland LJ, van der Wansem K, Weber K, Frystyk J, Lamberts SW & Janssen JA. Normal values of circulating insulin-like growth factor-I bioactivity in the healthy population: comparison with five widely used IGF-I immunoassays. Journal of Clinical Endocrinology and Metabolism 2008 93 2539-2545. (doi:10.1210/jc.2007-2454)