Normal values of circulating insulin-like growth factor-I bioactivity in the healthy population: Comparison with five widely used IGF-I immunoassays

Journal of Clinical Endocrinology and Metabolism

Volumn 93, Issue 7, 2008, Pages 2539-2545

  Brugts, Michael Pascal ^a   Ranke, Michael B ^b   Hofland, Leo J ^a   Van Der Wansem, Katy ^a   Weber, Karin ^b   Frystyk, Jan ^c   Lamberts, Steven W J ^a   Janssen, Joseph A M J L ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN C;

ADULT; AGED; ARTICLE; BIOLOGICAL ACTIVITY; CROSS-SECTIONAL STUDY; FEMALE; HUMAN; IMMUNOASSAY; INSULIN LIKE GROWTH FACTOR I SPECIFIC KINASE RECEPTOR ACTIVATION ASSAY; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; MENOPAUSE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

EID: 47549110969     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2007-2454     Document Type: Article

References (29)

1. Salmon Jr WD, Daughaday WH 1957 A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro. J Lab Clin Med 49:825-836
2. Klapper DG, Svoboda ME, Van Wyk JJ 1983 Sequence analysis of somatomedin-C: confirmation of identity with insulin-like growth factor I. Endocrinology 112:2215-2217
3. Daughaday WH, Hall K, Salmon Jr WD, Van den Brande JL, Van Wyk JJ 1987 On the nomenclature of the somatomedins and insulin-like growth factors. J Clin Endocrinol Metab 65:1075-1076
4. Zapf J, Walter H, Froesch ER 1981 Radioimmunological determination of insulinlike growth factors I and II in normal subjects and in patients with growth disorders and extrapancreatic tumor hypoglycemia. J Clin Invest 68:1321-1330
5. Furlanetto RW, Underwood LE, Van Wyk JJ, D'Ercole AJ 1977 Estimation of somatomedin-C levels in normals and patients with pituitary disease by radioimmunoassay. J Clin Invest 60:648-657
6. Scott MG, Cuca GC, Petersen JR, Lyle LR, Burleigh BD, Daughaday WH 1987 Specific immunoradiometric assay of insulin-like growth factor I with use of monoclonal antibodies. Clin Chem 33:2019-2023
7. Collett-Solberg PF, Cohen P 2000 Genetics, chemistry, and function of the IGF/IGFBP system. Endocrine 12:121-136
8. Chestnut RE, Quarmby V 2002 Evaluation of total IGF-I assay methods using samples from type I and type II diabetic patients. J Immunol Methods 259:11-24
9. Daughaday WH, Kapadia M, Mariz I 1987 Serum somatomedin binding proteins: physiologic significance and interference in radioligand assay. J Lab Clin Med 109:355-363
10. Frystyk J 2004 Free insulin-like growth factors - measurements and relationships to growth hormone secretion and glucose homeostasis. Growth Horm IGF Res 14:337-375
11. Pokrajac A, Wark G, Ellis AR, Wear J, Wieringa GE, Trainer PJ 2007 Variation in GH and IGF-I assays limits the applicability of international consensus criteria to local practice. Clin Endocrinol (Oxf) 67:65-70
12. Quarmby V, Quan C, Ling V, Compton P, Canova-Davis E 1998 How much insulin-like growth factor I (IGF-I) circulates? Impact of standardization on IGF-I assay accuracy. J Clin Endocrinol Metab 83:1211-1216
13. Clemmons DR 2001 Commercial assays available for insulin-like growth factor I and their use in diagnosing growth hormone deficiency. Horm Res 55(Suppl 2):73-79
14. Jones JI, Clemmons DR 1995 Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev 16:3-34
15. Chen JW, Ledet T, Orskov H, Jessen N, Lund S, Whittaker J, De Meyts P, Larsen MB, Christiansen JS, Frystyk J 2003 A highly sensitive and specific assay for determination of IGF-I bioactivity in human serum. Am J Physiol Endocrinol Metab 284:E1149-E1155
16. Sadick MD, Intintoli A, Quarmby V, McCoy A, Canova-Davis E, Ling V 1999 Kinase receptor activation (KIRA): a rapid and accurate alternative to endpoint bioassays. J Pharm Biomed Anal 19:883-891
17. LeRoith D, Werner H, Beitner-Johnson D, Roberts Jr CT 1995 Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr Rev 16:143-163
18. Laursen LS, Kjaer-Sorensen K, Andersen MH, Oxvig C 2007 Regulation of insulin-like growth factor (IGF) bioactivity by sequential proteolytic cleavage of IGF binding protein-4 and -5. Mol Endocrinol 21:1246-1257
19. Ranke MB, Osterziel KJ, Schweizer R, Schuett B, Weber K, Robbel P, Vornwald A, Blumenstock G, Elmlinger MW 2003 Reference levels of insulin-like growth factor I in the serum of healthy adults: comparison of four immunoassays. Clin Chem Lab Med 41:1329-1334
20. Frystyk J 2007 Utility of free IGF-I measurements. Pituitary 10:181-187
21. Clemmons DR 2007 IGF-I assays: current assay methodologies and their limitations. Pituitary 10:121-128
22. Lazarus NR 1972 Insulin and insulin-like substances in the circulation. Clin Endocrinol Metab 1:623-644
23. Lu K, Campisi J 1992 Ras proteins are essential and selective for the action of insulin-like growth factor 1 late in the G1 phase of the cell cycle in BALB/c murine fibroblasts. Proc Natl Acad Sci USA 89:3889-3893
24. Geier A, Weiss C, Beery R, Haimsohn M, Hemi R, Malik Z, Karasik A 1995 Multiple pathways are involved in protection of MCF-7 cells against death due to protein synthesis inhibition. J Cell Physiol 163:570-576
25. Strasburger CJ 1999 Methods in determining growth hormone concentrations: an immunofunctional assay. Pediatrics 104:1024-1028
26. Yu H, Mistry J, Nicar MJ, Khosravi MJ, Diamandis A, van Doorn J, Juul A 1999 Insulin-like growth factors (IGF-I, free IGF-I and IGF-II) and insulin-like growth factor binding proteins (IGFBP-2, IGFBP-3, IGFBP-6, and ALS) in blood circulation. J Clin Lab Anal 13:166-172
27. Leung KC, Johannsson G, Leong GM, Ho KK 2004 Estrogen regulation of growth hormone action. Endocr Rev 25:693-721
28. Ho KY, Evans WS, Blizzard RM, Veldhuis JD, Merriam GR, Samojlik E, Furlanetto R, Rogol AD, Kaiser DL, Thorner MO 1987 Effects of sex and age on the 24-hour profile of growth hormone secretion in man: importance of endogenous estradiol concentrations. J Clin Endocrinol Metab 64:51-58
29. Poehlman ET, Toth MJ, Ades PA, Rosen CJ 1997 Menopause-associated changes in plasma lipids, insulin-like growth factor I and blood pressure: a longitudinal study. Eur J Clin Invest 27:322-326