Leg extensor power and dehydroepiandrosterone sulfate, insulin-like growth factor-I and testosterone in healthy active elderly people

European Journal of Applied Physiology

Volumn 82, Issue 1-2, 2000, Pages 83-90

  Kostka, Tomasz ^a,b,c   Arsac, Laurent M ^b   Patricot, Marie C ^a   Berthouze, Sophie E ^d   Lacour, Jean René ^b   Bonnefoy, Marc ^a  

^a CENTRE HOSPITALIER LYON SUD   (France)

^b UNIVERSITÉ LYON 1   (France)

^c MEDICAL UNIVERSITY OF LODZ   (Poland)

^d UNIVERSITÉ JEAN MONNET   (France)

Author keywords

Ageing; Exercise; Fitness; Hormone; Muscle strength

Indexed keywords

PRASTERONE SULFATE; SOMATOMEDIN C; TESTOSTERONE;

AGE; AGED; ANTHROPOMETRY; ARTICLE; BICYCLE ERGOMETER; BODY MASS; CONTROLLED STUDY; FEMALE; HORMONE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; LEG EXERCISE; MALE; MUSCLE CONTRACTION; MUSCLE FUNCTION; MUSCLE STRENGTH; PHYSICAL ACTIVITY; PRIORITY JOURNAL; QUADRICEPS FEMORIS MUSCLE; QUESTIONNAIRE;

EID: 0034102232     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004210050655     Document Type: Article

References (55)

1. Alén M, Pakarinen A, Häkkinen K, Komi PV (1988) Responses of serum androgenic-anabolic and catabolic hormones to prolonged strength training. Int J Sports Med 9: 229-233
2. Andersen P, Saltin B (1985) Maximal perfusion of skeletal muscle in man. J Physiol (Lond) 366: 233-249
3. Aoyagi Y, Shephard R (1992) Aging and muscle function. Sports Med 14: 376-396
4. Arsac LM, Belli A, Lacour JR (1996) Muscle function during brief maximal exercise: accurate measurements on a friction-loaded cycle ergometer. Eur J Appl Physiol 74: 100-106
5. Berr C, Lafont S, Debuire B, Dartigues J, Baulieu E (1996) Relationship of dehydroepiandrosterone sulfate in the elderly with functional, psychological, and mental status, and short-term mortality: a French community-based study. Proc Natl Acad Sci 93: 13410-13415
6. Bonnefoy M, Kostka T, Berthouze SE, Lacour J-R (1996) Validation of physical activity questionnaire (QAPSE) in healthy elderly volunteers. Eur J Appl Physiol 74: 528-533
7. Bonnefoy M, Kostka T, Arsac LM, Berthouze SE, Lacour J-R (1998a) Peak anaerobic power in elderly men. Eur J Appl Physiol 77: 182-188
8. Bonnefoy M, Kostka T, Patricot MC, Berthouze SE, Mathian B, Lacour J-R (1998b) Physical activity and dehydroepiandrosterone sulfate, insulin-like growth factor-I and testosterone in healthy active elderly people. Age Ageing 27: 745-751
9. Boonen S, Lysens R, Verbeke G, Joosten E, Dejaeger E, Pelemans W, Flamaing J, Bouillon R (1998) Relationship between age-associated endocrine deficiencies and muscle function in elderly women: a cross-sectional study. Age Ageing 27: 449-454
10. Bosco C, Komi PV (1980) Influence of aging on the mechanical behaviour of leg extensor muscles. Eur J Appl Physiol 45: 209-219
11. Bremner W, Vitiello M, Prinz P (1983) Loss of circadian rhythmicity in blood testosterone levels with aging in normal men. J Clin Endocrinol Metab 56: 1278-1281
12. Brooks S, Faulkner J (1994) Skeletal muscle weakness in old age: underlying mechanisms. Med Sci Sports Exerc 26: 432-439
13. Busso T, Häkkinen K, Pakarinen A, Carasso C, Lacour J-R, Komi PV, Kauhanen H (1990) A systems model of training responses and its relationship to hormonal responses in elite weight-lifters. Eur J Appl Physiol 61: 48-54
14. Clarkson PM, Kroll W, Melchionda AM (1981) Age, isometric strength, rate of tension development and fiber type composition. J Gerontol 36: 648-653
15. Craig BW, Brown R, Everhart J (1989) Effects of progressive resistance training on growth hormone and testosterone levels in young and elderly subjects. Mech Ageing Dev 49: 159-169
16. Crowley MA, Matt KS (1996) Hormonal regulation of skeletal muscle hypertrophy in rats: the testosterone to cortisol ratio. Eur J Appl Physiol 73: 66-72
17. Davies C, Thomas D, White M (1986) Mechanical properties of young and elderly human muscle. Acta Med Scand [Suppl] 711: 219-226
18. Deschenes MR, Maresh CM, Armstrong LE, Covault J, Kraemer WJ, Crivello JF (1994) Endurance and resistance exercise induce muscle fiber type specific responses in androgen binding capacity. J Steroid Biochem Mol Biol 50: 175-179
19. Durnin JV, Womersley J (1974) Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. Br J Nutr 32: 77-97
20. Guralnik JM, Ferrucci L, Simonsick EM, Salive ME, Wallace RB (1995) Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. N Engl J Med 332: 556-561
21. Häkkinen K, Pakarinen A (1993) Muscle strength and serum testosterone, cortisol, and SHBG concentrations in middle-aged and elderly men and women. Acta Physiol Scand 148: 199-207
22. Häkkinen K, Pakarinen A (1994) Serum hormones and strength development during strength training in middle-aged and elderly males and females. Acta Physiol Scand 150: 211-219
23. Häkkinen K, Pakarinen A (1995) Acute hormonal responses to heavy resistance exercise in men and women at different ages. Int J Sports Med 16: 507-513
24. Häkkinen K, Pastinen UM, Karsikas R, Linnamo V (1995) Neuromuscular performance in voluntary bilateral and unilateral contraction and during electrical stimulation in men at different ages. Eur J Appl Physiol 70: 518-527
25. Häkkinen K, Kraemer WJ, Kallinen M, Linnamo V, Pastinen UM, Newton RU (1996) Bilateral and unilateral neuromuscular function and muscle cross-sectional area in middle-aged and elderly men and women. J Gerontol Biol Sci 51: B21-29
26. Häkkinen K, Kallinen M, Izquierdo M, Jokelainen K, Lassila H, Mälkiä E, Kraemer WJ, Newton RU, Alen M (1998a) Changes in agonist-antagonist EMG, muscle CSA, and force during strength training in middle-aged and older men. J Appl Physiol 84: 1341-1349
27. Häkkinen K, Pakarinen A, Newton RU, Kraemer WJ (1998b) Acute hormone responses to heavy resistance lower and upper extremity exercise in young versus old men. Eur J Appl Physiol 77: 312-319
28. Harridge S, Magnusson G, Saltin B (1997) Life-long endurance-trained elderly men have high aerobic power, but have similar muscle strength to non-active elderly men. Aging Clin Exp Res 9: 80-87
29. Hautier C, Linossier M, Belli A, Lacour J, Arsac L (1996) Optimal velocity for maximal power production in non-isokinetic cycling is related to muscle fibre type composition. Eur J Appl Physiol 74: 114-118
30. Holloway L, Butterfield G, Hintz R, Gesundheit N, Marcus R (1994) Effects of recombinant human growth hormone on metabolic indices, body composition, and bone turnover in healthy elderly women. J Clin Endocrinol Metab 79: 470-479
31. Izquierdo M, Aguado X, Gonzalez R, López JL, Häkkinen K (1999) Maximal and explosive force production capacity and balance performance in men of different ages. Eur J Appl Physiol 79: 260-267
32. Jones P, Pearson J (1969) Anthropometric determination of leg fat and muscle plus bone volumes in young male and female adults. J Physiol (Lond) 204: 63P-66P
33. Kiel DP, Puhl J, Rosen CJ, Berg K, Murphy JB, MacLean DB (1998) Lack of association between insulin-like growth factor-I and body composition, muscle strength, physical performance or self-reported mobility among older persons with functional limitations. J Am Geriatr Soc 46: 822-828
34. Kostka T, Bonnefoy M, Arsac L, Berthouze S, Belli A, Lacour J-R (1997) Habitual physical activity and peak anaerobic power in elderly women. Eur J Appl Physiol 76: 81-87
35. Kraemer WJ, Häkkinen K, Newton RU, McCormick M, Nindl BC, Volek JS, Gotshalk LA, Fleck SJ, Campbell WW, Gordon SE, Farrell PA, Evans WJ (1998) Acute hormonal responses to heavy resistance exercise in younger and older men. Eur J Appl Physiol 77: 206-211
36. Kraemer WJ, Häkkinen K, Newton RU, Nindl BC, Volek JS, McCormick M, Gotshalk LA, Gordon SE, Fleck SJ, Campbell WW, Putukian M, Evans WJ (1999) Effects of heavy-resistance training on hormonal response patterns in younger vs. older men. J Appl Physiol 87: 982-992
37. Lakomy HKA (1986) Measurements of work and power output using friction-loaded cycle ergometers. Ergonomics 29: 509-517
38. Lamberts SWJ, van der Beld AW, van der Lely A-J (1997) The endocrinology of aging. Science 278: 419-424
39. Liu C, Laughlin G, Fischer U, Yen S (1990) Marked attenuation of ultradian and arcadian rhythms of dehydroepiandrosterone in postmenopausal women: evidence for a reduced 17,20-desmolase enzymatic activity. J Clin Endocrinol Metab 71: 900-906
40. Morales A, Nolan J, Nelson J, Yen S (1994) Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. J Clin Endocrinol Metab 78: 1360-1367
41. Morales AJ, Haubrich RH, Hwang JY, Asakura H, Yen SSC (1998) Effects of six-month treatment with a 100-mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women. Clin Endocrinol 49: 421-432
42. Morley J, Perry H, Kaiser F, Kraenzle D, Jensen J, Houston K, Mattammal MHP Jr (1993) Effects of testosterone replacement therapy in old hypogonadal males: a preliminary study. J Am Geriatr Soc 41: 149-152
43. Niclas BJ, Ryan AJ, Treuth MM, Harman SM, Blackman MR, Hurly BF, Rogers MA (1995) Testosterone, growth hormone and IGF-I responses to acute and chronic resistive exercise in men aged 50-70 years. Int J Sports Med 16: 445-450
44. Papadakis MA, Grady D, Tierney MJ, Black D, Wells L, Grunfeld C (1995) Insulin-like growth factor 1 and functional status in healthy older men. J Am Geriatr Soc 43: 1350-1355
45. Proctor DN, Balagopal P, Nair KS (1998) Age-related sarcopenia in humans is associated with reduced synthetic rates of specific muscle proteins. J Nutr 128 [Suppl 2]: 351S-355S
46. Ravaglia G, Forti P, Maioli F, Boschi F, Bernardi M, Pratelli L, Pizzoferrato A, Gasbarrini G (1996) The relationship of dehydroepiandrosterone sulfate (DHEAS) to endocrine-metabolic parameters and functional status in the oldest-old. Results from an Italian study on healthy free-living over-ninety-years-olds. J Clin Endocrinol Metab 81: 1173-1178
47. Rudman D, Feller AG, Nagaraj HS, Gergans GA, Lalitha PY, Goldberg AF, Schlenker RA, Cohn L, Rudman IW, Mattson DE (1990) Effects of human growth hormone in men over 60 years old. N Engl J Med 323: 1-6
48. Saltin B (1985) Hemodynamic adaptations to exercise. Am J Cardiol 55: 42D-47D
49. Taaffe DR, Pruitt L, Reim J, Hintz RL, Butterfield G, Hoffman AR, Marcus R (1994) Effect of recombinant human growth hormone on the muscle strength response to resistance exercise in elderly men. J Clin Endocrinol Metab 79: 1361-1366
50. Thelen DG, Schultz AB, Alexander NB, Ashton-Miller JA (1996) Effects of age on rapid ankle torque development. J Gerontol Med Sci 51: M226-M232
51. Thompson JL, Butterfield GE, Marcus R, Hintz RL, van Loan M, Ghiron L, Hoffman AR (1995) The effects of recombinant human insulin-like growth factor-I and growth hormone on body composition in elderly women. J Clin Endocrinol Metab 80: 1845-1852
52. Urban RJ, Bodenburg YH, Gilkison C, Foxworth J, Coggan AR, Wolfe RR, Ferrando A (1995) Testosterone administration to elderly men increases skeletal muscle strength and protein synthesis. Am J Physiol 269: E820-E826
53. Vandervoort A, McComas A (1986) Contractile changes in opposing muscles of the human ankle joint with aging. J Appl Physiol 61: 361-367
54. Vermeulen A, Rubens R, Verdonck L (1972) Testosterone secretion and metabolism in male senescence. J Clin Endocrinol 34: 730-735
55. Young A, Skelton DA (1994) Applied physiology of strength and power in old age. Int J Sports Med 15: 149-152