Synthesis, cytotoxicity, and COMPARE analysis of ferrocene and [3]ferrocenophane tetrasubstituted olefin derivatives against human cancer cells

ChemMedChem

Volumn 5, Issue 12, 2010, Pages 2039-2050

  Görmen, Meral ^a   Pigeon, Pascal ^a   Top, Siden ^a   Hillard, Elizabeth A ^a   Huché, Michel ^a   Hartinger, Christian G ^b   de Montigny, Frédéric ^a   Plamont, Marie Aude ^a   Vessières, Anne ^a   Jaouen, Gérard ^a  

^a PSL RESEARCH UNIVERSITY   (France)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

Bioorganometallic chemistry; Cell culture; Cytotoxicity; Drug discovery; Ferrocenes

Indexed keywords

1 (4 ACETOXYPHENYL) 1 (4 HYDROXYPHENYL) 2 FERROCENYLBUT 1 ENE; 1 (4 ACETYLOXYPHENYL) 1 PHENYL 2 FERROCENYLBUT 1 ENE; 1 (4 AMINOPHENYL) 1 (4 HYDROXYPHENYL) 2 FERROCENYLBUT 1 ENE; 1 (4 N ACETAMIDOPHENYL) 1 (4 HYDROXYPHENYL) 2 FERROCENYLBUT 1 ENE; 1 [(4 ACETYLOXYPHENYL) (4 HYDROXYPHENYL)METHYLIDENE] [3]FERROCENOPHANE; 1 [(4 ACETYLOXYPHENYL)(PHENYL)METHYLIDENE] [3]FERROCENOPHANE; 1 [(4 BROMOPHENYL) (4 CYANOPHENYL)METHYLIDENE] [3]FERROCENOPHANE; 1 [(4 BROMOPHENYL)PHENYLMETHYLIDENE] [3]FERROCENOPHANE; 1 [(4 CYANOPHENYL)PHENYLMETHYLIDENE] [3]FERROCENOPHANE; 1 [(DI 4 ACETYLOXYPHENYL)METHYLIDENE] [3]FERROCENOPHANE; 1 [(DI 4 BROMOPHENYL)METHYLIDENE] [3]FERROCENOPHANE; 1 [(DI 4 CYANOPHENYL)METHYLIDENE] [3]FERROCENOPHANE; ALKENE DERIVATIVE; APHIDICOLIN; BLEOMYCIN; CISPLATIN; FERROCENE; FERROCENOPHANE; IRON; PRODRUG; TAMOXIFEN; TOPOTECAN; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CANCER THERAPY; CARCINOGEN DNA INTERACTION; CENTRAL NERVOUS SYSTEM TUMOR; CHEMICAL REACTION; CHEMICAL STRUCTURE; COLON CANCER; CROSS COUPLING REACTION; CYTOTOXICITY; CYTOTOXICITY TEST; DRUG ACETYLATION; DRUG PROTEIN BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; KIDNEY CANCER; LEUKEMIA; LUNG NON SMALL CELL CANCER; MELANOMA; MOUSE; NONHUMAN; OVARY CANCER; OXIDATION; PRIORITY JOURNAL; PROSTATE CANCER; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY;

ALKENES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; DRUG SCREENING ASSAYS, ANTITUMOR; FERROUS COMPOUNDS; HUMANS; KINETICS; MOLECULAR CONFORMATION; NEOPLASMS;

EID: 78651498958     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201000286     Document Type: Article

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