메뉴 건너뛰기




Volumn 133, Issue 2, 2011, Pages 704-709

Identification and pharmacological characterization of the anti-inflammatory principal of the leaves of dwarf elder (Sambucus ebulus L.)

Author keywords

Adoxacea; Anti inflammatory activity; HUVEC; ICAM 1; Sambucus ebulus L.; TNF ; Ursolic acid; VCAM 1

Indexed keywords

ANTIINFLAMMATORY AGENT; PARTHENOLIDE; SAMBUCUS EBULUS EXTRACT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; URSOLIC ACID; VASCULAR CELL ADHESION MOLECULE 1;

EID: 78651411659     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.10.049     Document Type: Article
Times cited : (52)

References (30)
  • 1
    • 21644440395 scopus 로고    scopus 로고
    • Ursolic acid induces Bax-dependent apoptosis through the caspase-3 pathway in endometrial cancer SNG-II cells
    • Y. Achiwa, K. Hasegawa, T. Komiya, and Y. Udagawa Ursolic acid induces Bax-dependent apoptosis through the caspase-3 pathway in endometrial cancer SNG-II cells Oncology Reports 13 2005 51 57
    • (2005) Oncology Reports , vol.13 , pp. 51-57
    • Achiwa, Y.1    Hasegawa, K.2    Komiya, T.3    Udagawa, Y.4
  • 3
    • 0025942340 scopus 로고
    • Protective effect of oleanolic acid and ursolic acid against lipid peroxidation
    • S. Balanehru, and B. Nagarajan Protective effect of oleanolic acid and ursolic acid against lipid peroxidation Biochemistry International 24 1991 981 990
    • (1991) Biochemistry International , vol.24 , pp. 981-990
    • Balanehru, S.1    Nagarajan, B.2
  • 7
    • 0030002548 scopus 로고    scopus 로고
    • Anti-invasive activity of ursolic acid correlates with the reduced expression of matrix metalloproteinase-9 (MMP-9) in HT1080 human fibrosarcoma cells
    • H.J. Cha, S.K. Bae, H.Y. Lee, O.H. Lee, H. Sato, M. Seiki, B.C. Park, and K.W. Kim Anti-invasive activity of ursolic acid correlates with the reduced expression of matrix metalloproteinase-9 (MMP-9) in HT1080 human fibrosarcoma cells Cancer Research 56 1996 2281 2284
    • (1996) Cancer Research , vol.56 , pp. 2281-2284
    • Cha, H.J.1    Bae, S.K.2    Lee, H.Y.3    Lee, O.H.4    Sato, H.5    Seiki, M.6    Park, B.C.7    Kim, K.W.8
  • 8
    • 32344441103 scopus 로고    scopus 로고
    • Antiinflammatory activity of Sambucus ebulus hexane extracts
    • M.A. Ebrahimzadeh, M. Mahmoudi, and E. Salimi Antiinflammatory activity of Sambucus ebulus hexane extracts Fitoterapia 77 2006 146 148
    • (2006) Fitoterapia , vol.77 , pp. 146-148
    • Ebrahimzadeh, M.A.1    Mahmoudi, M.2    Salimi, E.3
  • 9
    • 78651410367 scopus 로고    scopus 로고
    • Sambucus
    • 6th ed. W. Blaschek, S. Ebel, E. Hackenthal, U. Holzgrabe, K. Keller, J. Reichling, V. Schulz, Wissenschaftliche Verlagsgesellschaft mbH Stuttgart, Germany.
    • A. Hiermann Sambucus 6th ed. W. Blaschek, S. Ebel, E. Hackenthal, U. Holzgrabe, K. Keller, J. Reichling, V. Schulz, Hagers Enzyklopädie der Arzneistoffe und Drogen vol. 14 2007 Wissenschaftliche Verlagsgesellschaft mbH Stuttgart, Germany 173 189
    • (2007) Hagers Enzyklopädie der Arzneistoffe und Drogen , vol.14 , pp. 173-189
    • Hiermann, A.1
  • 10
    • 26944436691 scopus 로고    scopus 로고
    • Ursolic acid promotes the release of macrophage migration inhibitory factor via ERK2 activation in resting mouse macrophages
    • Y. Ikeda, A. Murakami, and H. Ohigashi Ursolic acid promotes the release of macrophage migration inhibitory factor via ERK2 activation in resting mouse macrophages Biochemical Pharmacology 70 2005 1497 1505
    • (2005) Biochemical Pharmacology , vol.70 , pp. 1497-1505
    • Ikeda, Y.1    Murakami, A.2    Ohigashi, H.3
  • 13
    • 34548011290 scopus 로고    scopus 로고
    • Ursolic acid ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by d-galactose
    • J. Lu, Y.L. Zheng, D.M. Wu, L. Luo, D.X. Sun, and Q. Shan Ursolic acid ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by d-galactose Biochemical Pharmacology 74 2007 1078 1090
    • (2007) Biochemical Pharmacology , vol.74 , pp. 1078-1090
    • Lu, J.1    Zheng, Y.L.2    Wu, D.M.3    Luo, L.4    Sun, D.X.5    Shan, Q.6
  • 14
    • 16844366650 scopus 로고    scopus 로고
    • Nuclear factor-κB inhibitors as sensitizers to anticancer drugs
    • C. Nakanishi, and M. Toi Nuclear factor-κB inhibitors as sensitizers to anticancer drugs Nature Reviews Cancer 5 2005 297 309
    • (2005) Nature Reviews Cancer , vol.5 , pp. 297-309
    • Nakanishi, C.1    Toi, M.2
  • 16
    • 39549121695 scopus 로고    scopus 로고
    • Antigenotoxic effects of quercetin, rutin and ursolic acid on HepG2 cells: Evaluation by the comet assay
    • A.A. Ramos, C.F. Lima, M.L. Pereira, M. Fernandes-Ferreira, and C. Pereira-Wilson Antigenotoxic effects of quercetin, rutin and ursolic acid on HepG2 cells: evaluation by the comet assay Toxicology Letters 177 2008 66 73
    • (2008) Toxicology Letters , vol.177 , pp. 66-73
    • Ramos, A.A.1    Lima, C.F.2    Pereira, M.L.3    Fernandes-Ferreira, M.4    Pereira-Wilson, C.5
  • 17
    • 55249118571 scopus 로고    scopus 로고
    • Effect of ursolic acid, a triterpenoid antioxidant, on ultraviolet-B radiation-induced cytotoxicity, lipid peroxidation and DNA damage in human lymphocytes
    • S. Ramachandran, and N.R. Prasad Effect of ursolic acid, a triterpenoid antioxidant, on ultraviolet-B radiation-induced cytotoxicity, lipid peroxidation and DNA damage in human lymphocytes Chemico-Biological Interactions 176 2008 99 107
    • (2008) Chemico-Biological Interactions , vol.176 , pp. 99-107
    • Ramachandran, S.1    Prasad, N.R.2
  • 18
    • 78651394483 scopus 로고
    • Data of the constituents of Sambucus nigra L. III. Determination of ursol and oleanolic acids, amyrin and sterol contents from Sambuci DAB 7 flowers
    • W. Richter, and G. Wilhun Data of the constituents of Sambucus nigra L. III. Determination of ursol and oleanolic acids, amyrin and sterol contents from Sambuci DAB 7 flowers Pharmazeutische Zeitung 122 1977 1567 1571
    • (1977) Pharmazeutische Zeitung , vol.122 , pp. 1567-1571
    • Richter, W.1    Wilhun, G.2
  • 20
    • 0042090509 scopus 로고    scopus 로고
    • Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: Correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1
    • S. Shishodia, S. Majumdar, S. Banerjee, and B.B. Aggarwal Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1 Cancer Research 63 2003 4375 4383
    • (2003) Cancer Research , vol.63 , pp. 4375-4383
    • Shishodia, S.1    Majumdar, S.2    Banerjee, S.3    Aggarwal, B.B.4
  • 22
    • 0037359363 scopus 로고    scopus 로고
    • Cardiovascular, antihyperlipidemic and antioxidant effects of oleanolic and ursolic acids in experimental hypertension
    • L.O. Somova, A. Nadar, P. Rammanan, and F.O. Shode Cardiovascular, antihyperlipidemic and antioxidant effects of oleanolic and ursolic acids in experimental hypertension Phytomedicine 10 2003 115 121
    • (2003) Phytomedicine , vol.10 , pp. 115-121
    • Somova, L.O.1    Nadar, A.2    Rammanan, P.3    Shode, F.O.4
  • 23
    • 35248872474 scopus 로고    scopus 로고
    • Ursolic acid from the Chinese herb danshen (Salvia miltiorrhiza L.) upregulates eNOS and down regulates Nox4 expression in human endothelial cells
    • K. Steinkamp-Fenske, L. Bollinger, N. Voller, H. Xu, Y. Yao, R. Bauer, U. Förstermann, and H. Li Ursolic acid from the Chinese herb danshen (Salvia miltiorrhiza L.) upregulates eNOS and down regulates Nox4 expression in human endothelial cells Atherosclerosis 195 2007 e104 e111
    • (2007) Atherosclerosis , vol.195
    • Steinkamp-Fenske, K.1    Bollinger, L.2    Voller, N.3    Xu, H.4    Yao, Y.5    Bauer, R.6    Förstermann, U.7    Li, H.8
  • 24
    • 0034193436 scopus 로고    scopus 로고
    • Ursolic acid inhibits cyclooxygenase-2 transcription in human mammary epithelial cells
    • K. Subbaramaiah, P. Michaluart, M.B. Sporn, and A.J. Dannenberg Ursolic acid inhibits cyclooxygenase-2 transcription in human mammary epithelial cells Cancer Research 60 2000 2399 2404
    • (2000) Cancer Research , vol.60 , pp. 2399-2404
    • Subbaramaiah, K.1    Michaluart, P.2    Sporn, M.B.3    Dannenberg, A.J.4
  • 25
    • 27744535410 scopus 로고    scopus 로고
    • Inhibitory effect on TNFalpha-induced IL-8 production in the HT29 cell of constituents from the leaf and stem of Weigela subsessilis
    • P.T. Thuong, W.Y. Jin, J.P. Lee, R.S. Seong, Y.M. Lee, Y.H. Seong, K.S. Song, and K.H. Bae Inhibitory effect on TNFalpha-induced IL-8 production in the HT29 cell of constituents from the leaf and stem of Weigela subsessilis Archives of Pharmacal Research 28 2005 1135 1141
    • (2005) Archives of Pharmacal Research , vol.28 , pp. 1135-1141
    • Thuong, P.T.1    Jin, W.Y.2    Lee, J.P.3    Seong, R.S.4    Lee, Y.M.5    Seong, Y.H.6    Song, K.S.7    Bae, K.H.8
  • 27
    • 45249120791 scopus 로고    scopus 로고
    • IFN-gamma regulation of ICAM-1 receptors in bronchial epithelial cells: Soluble ICAM-1 release inhibits human rhinovirus infection
    • S.C. Whiteman, and M.A. Spiteri IFN-gamma regulation of ICAM-1 receptors in bronchial epithelial cells: soluble ICAM-1 release inhibits human rhinovirus infection Journal of Inflammation 5 2008 doi:10.1186/1476-9255-5-8
    • (2008) Journal of Inflammation , vol.5
    • Whiteman, S.C.1    Spiteri, M.A.2
  • 28
    • 0343765814 scopus 로고    scopus 로고
    • Inhibitory effects of Turkish folk remedies on inflammatory cytokines: Interleukin-1α, interleukin-1β and tumor necrosis factor α
    • E. Yesilada, O. Üstün, E. Sezik, Y. Takaishi, Y. Ono, and G.J. Honda Inhibitory effects of Turkish folk remedies on inflammatory cytokines: interleukin-1α, interleukin-1β and tumor necrosis factor α Journal of Ethnopharmacology 58 1997 59 73
    • (1997) Journal of Ethnopharmacology , vol.58 , pp. 59-73
    • Yesilada, E.1    Üstün, O.2    Sezik, E.3    Takaishi, Y.4    Ono, Y.5    Honda, G.J.6
  • 29
    • 0031330045 scopus 로고    scopus 로고
    • Evaluation of the anti-inflammatory activity of the Turkish medicinal plant Sambucus ebulus
    • E. Yesilada Evaluation of the anti-inflammatory activity of the Turkish medicinal plant Sambucus ebulus Chemistry of Natural Compounds 33 1997 539 540
    • (1997) Chemistry of Natural Compounds , vol.33 , pp. 539-540
    • Yesilada, E.1
  • 30
    • 48849111682 scopus 로고    scopus 로고
    • Protection of chlorophyllin against oxidative damage by inducing HO-1 and NQO1 expression mediated by PI3K/Akt and Nrf2
    • Y. Zhang, L. Guan, X. Wang, T. Wen, J. Xing, and J. Zhao Protection of chlorophyllin against oxidative damage by inducing HO-1 and NQO1 expression mediated by PI3K/Akt and Nrf2 Free Radical Research 42 2008 362 371
    • (2008) Free Radical Research , vol.42 , pp. 362-371
    • Zhang, Y.1    Guan, L.2    Wang, X.3    Wen, T.4    Xing, J.5    Zhao, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.