Role of pocket flexibility in the modulation of estrogen receptor alpha by key residue arginine 394

Environmental Toxicology and Chemistry

Volumn 30, Issue 2, 2011, Pages 330-336

  Mu, Yunsong ^a,b   Peng, Sufen ^a   Zhang, Aiqian ^b   Wang, Liansheng ^a  

^a NANJING UNIVERSITY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Estradiol derivatives; Flexible docking; Human estrogen receptor alpha; Induced fit effect; Recombinant gene yeast

Indexed keywords

ESTRADIOL DERIVATIVES; FLEXIBLE DOCKING; HUMAN ESTROGEN RECEPTORS; INDUCED FIT; RECOMBINANT GENE YEAST;

ALGEBRA; BINDING ENERGY; DOCKING; GENES; HEALTH RISKS; HYDROPHOBICITY; LIGANDS; MOLECULAR STRUCTURE; YEAST;

AMINO ACIDS;

16 EPOESTRIOL; 17ALPHA ETHYLESTRADIOL 3 CYCLOPENTYLETHER; ARGININE; BETA ESTRADIOL 3,17 DIACETATE; ESTRADIOL ACETATE; ESTRADIOL CIPIONATE; ESTRADIOL PROPIONATE; ESTRADIOL VALERATE; ESTROGEN RECEPTOR ALPHA; STEROID HORMONE; UNCLASSIFIED DRUG;

AMINO ACID; BIOASSAY; ENVIRONMENTAL RISK; ESTROGENIC COMPOUND; ETHER; EXPERIMENTAL STUDY; HEALTH IMPACT; HORMONE; HYDROPHOBICITY; LIGAND; METABOLITE; MOLECULAR ANALYSIS; PUBLIC HEALTH; RECOMBINATION; STEROID; YEAST;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BIOASSAY; CHEMICAL STRUCTURE; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; CONTROLLED STUDY; FUNGAL STRAIN; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SIMULATION; YEAST; YEAST CELL;

ARGININE; BETA-GALACTOSIDASE; BINDING SITES; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; HUMANS; LIGANDS; MODELS, MOLECULAR; PROTEIN BINDING;

EID: 78651371133     PISSN: 07307268     EISSN: 15528618     Source Type: Journal    
DOI: 10.1002/etc.389     Document Type: Article

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