Up-regulation of the isoenzymes MAO-A and MAO-B in the human basal ganglia and pons in Huntington's disease revealed by quantitative enzyme radioautography

Brain Research

Volumn 1370, Issue , 2011, Pages 204-214

  Richards, Grayson ^a   Messer, Juerg ^a   Waldvogel, Henry J ^b   Gibbons, Hannah M ^b   Dragunow, Mike ^b   Faull, Richard L M ^b   Saura, Josep ^c  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Enzyme inhibitor; Gliosis; In vitro binding; Inflammatory response; Lazabemide; Mapping; Monoamine oxidase; Neurodegeneration; Ro 41 1049

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; LAZABEMIDE H 3; LIGAND; N (2 AMINOETHYL) 5 (3 FLUOROPHENYL) 4 THIAZOLECARBOXAMIDE; N (2 AMINOETHYL) 5 (3 FLUOROPHENYL) 4 THIAZOLECARBOXAMIDE H 3; UNCLASSIFIED DRUG;

ADULT; AGED; AGING; ALZHEIMER DISEASE; ARTICLE; ASTROCYTE; AUTORADIOGRAPHY; BASAL GANGLION; BEHAVIOR; BRAIN; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; CORRELATION ANALYSIS; DISEASE SEVERITY; ENZYME ACTIVITY; FEMALE; GABAERGIC SYSTEM; GENETIC DISORDER; GLIOSIS; GLOBUS PALLIDUS; HUMAN; HUMAN TISSUE; HUNTINGTON CHOREA; IN VITRO STUDY; INSULA; ISOTOPE LABELING; MALE; MOTOR DYSFUNCTION; MOVEMENT (PHYSIOLOGY); NERVE CELL; NERVE CELL NETWORK; NERVE DEGENERATION; OXIDATIVE STRESS; PONS; PRIORITY JOURNAL; PUTAMEN; QUANTITATIVE ANALYSIS; SUBSTANTIA NIGRA; SUBSTANTIA NIGRA PARS COMPACTA; UPREGULATION;

ADULT; AGED; BASAL GANGLIA; BIOLOGICAL MARKERS; FEMALE; HUMANS; HUNTINGTON DISEASE; ISOENZYMES; MALE; MIDDLE AGED; MONOAMINE OXIDASE; OXIDATIVE STRESS; PONS; UP-REGULATION;

EID: 78651367966     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.11.020     Document Type: Article

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