Oxidative metabolism of the anti-cancer agent mitoxantrone by horseradish, lacto-and lignin peroxidase

Biochimie

Volumn 93, Issue 2, 2011, Pages 217-226

  Brück, Thomas B ^a,c   Brück, Dieter W ^a,b  

^a FLORIDA ATLANTIC UNIVERSITY   (United States)

^b BDW Analytical Services and Consulting   (Germany)

^c SÜD CHEMIE AG   (Germany)

Author keywords

Cancer; Mitoxantrone drug metabolism; Novel enzymatic oxidation cascade

Indexed keywords

ANTHRAQUINONE; CARBOXYLIC ACID; DICARBOXYLIC ACID DERIVATIVE; DRUG METABOLITE; HEXAHYDRONAPHTHO [2,3 F] QUINOXALINE 7,12 DIONE; HORSERADISH PEROXIDASE; HYDROGEN PEROXIDE; LACTO PEROXIDASE; LIGNIN PEROXIDASE; LIPID PEROXIDASE; MITOXANTRONE; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ARTICLE; CATALYSIS; CHROMATOPHORE; DRUG OXIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORSERADISH; HUMAN; MASS SPECTROMETRY;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOCATALYSIS; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; HORSERADISH PEROXIDASE; HYDROGEN PEROXIDE; HYDROGEN-ION CONCENTRATION; LACTOPEROXIDASE; MITOXANTRONE; OXIDATION-REDUCTION; PEROXIDASES; PHANEROCHAETE; SPECTROPHOTOMETRY, ULTRAVIOLET;

ARMORACIA RUSTICANA;

EID: 78651338653     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2010.09.015     Document Type: Article

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