-
1
-
-
33645526144
-
Cancer Statistics, 2006
-
Jemal A, Siegel R, Ward E, et al. Cancer Statistics, 2006. CA Cancer J Clin 2006; 56: 106-130.
-
(2006)
CA Cancer J Clin
, vol.56
, pp. 106-130
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
2
-
-
0028567070
-
The role of the cellular antioxidant defense in oxidant carcinogenesis
-
Cerruti P, Ghosh R, Oya Y, et al. The role of the cellular antioxidant defense in oxidant carcinogenesis. Environ Health Perspect 1994; 102 Suppl 10: 123-129.
-
(1994)
Environ Health Perspect
, vol.102
, Issue.SUPPL. 10
, pp. 123-129
-
-
Cerruti, P.1
Ghosh, R.2
Oya, Y.3
-
3
-
-
0012550211
-
Prooxidant states and tumor promotion
-
Cerruti P. Prooxidant states and tumor promotion. Science 1985; 227: 7634-7638.
-
(1985)
Science
, vol.227
, pp. 7634-7638
-
-
Cerruti, P.1
-
4
-
-
0024382255
-
Oxidative influence in development and differentiation: And overview of a free radical theory of development
-
Allen R, Balon A. Oxidative influence in development and differentiation: and overview of a free radical theory of development. Free Radic Biol Med 1989; 6: 631-661.
-
(1989)
Free Radic Biol Med
, vol.6
, pp. 631-661
-
-
Allen, R.1
Balon, A.2
-
5
-
-
0027485461
-
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
-
Hockenbery D, Oltvai Z, Yin X, et al. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993; 75: 241-251.
-
(1993)
Cell
, vol.75
, pp. 241-251
-
-
Hockenbery, D.1
Oltvai, Z.2
Yin, X.3
-
6
-
-
0034657292
-
Tyrosine nitration of c-SRC tyrosine kinase in human pancreatic ductal adeno-carcinoma
-
MacMillan-Crow L, Greendorfer J, Vickers S, et al. Tyrosine nitration of c-SRC tyrosine kinase in human pancreatic ductal adeno-carcinoma. Arch Biochem Biophys 2000; 377: 350-356.
-
(2000)
Arch Biochem Biophys
, vol.377
, pp. 350-356
-
-
MacMillan-Crow, L.1
Greendorfer, J.2
Vickers, S.3
-
8
-
-
0002030285
-
Free radicals, cancer, and aging
-
In: Johnson, Jr, JE, Walford R, Harmon D, Miquel J, (Eds). Alan R Liss Inc.986
-
Oberley LW, Oberley TD. Free radicals, cancer, and aging. In: Johnson, Jr, JE, Walford R, Harmon D, Miquel J, (Eds). Free Radicals, Aging, and Degenerative Diseases. Alan R Liss Inc.986; 325-381.
-
Free Radicals, Aging, and Degenerative Diseases
, pp. 325-381
-
-
Oberley, L.W.1
Oberley, T.D.2
-
9
-
-
0024270397
-
Role of antioxidant enzymes in cell immortalization and transformation
-
Oberley L, Oberley T. Role of antioxidant enzymes in cell immortalization and transformation. Mol Cell Biochem 1988; 84: 147-153.
-
(1988)
Mol Cell Biochem
, vol.84
, pp. 147-153
-
-
Oberley, L.1
Oberley, T.2
-
11
-
-
0018893779
-
High incidence of extrapancreatic carcinoma in chronic pancreatitis?
-
Ammann R, Knoblauch M, Mohr P. High incidence of extrapancreatic carcinoma in chronic pancreatitis? Scand J Gastroenterol 1980; 15: 395-399.
-
(1980)
Scand J Gastroenterol
, vol.15
, pp. 395-399
-
-
Ammann, R.1
Knoblauch, M.2
Mohr, P.3
-
12
-
-
0027507332
-
Pancreatic duct obstruction as potential etiology of pancreatic adenocarcinoma
-
Traverso L, Kozarek R, Simpson T, et al. Pancreatic duct obstruction as potential etiology of pancreatic adenocarcinoma. Am J Gastroenterol 1993; 88(1):117-119.
-
(1993)
Am J Gastroenterol
, vol.88
, Issue.1
, pp. 117-119
-
-
Traverso, L.1
Kozarek, R.2
Simpson, T.3
-
13
-
-
0029080314
-
Expression and in situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer
-
Gress TM, Muller-Pillasch F, Lerch MM, et al. Expression and in situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer. Int J Cancer 1995; 62: 407-413.
-
(1995)
Int J Cancer
, vol.62
, pp. 407-413
-
-
Gress, T.M.1
Muller-Pillasch, F.2
Lerch, M.M.3
-
14
-
-
0028157921
-
Human ductal adenocarcinomas of the pancreas express extracellular matrix proteins
-
Lohr M, Trautmann B, Gottler M, et al. Human ductal adenocarcinomas of the pancreas express extracellular matrix proteins. Br J Cancer 1994; 69: 144-151.
-
(1994)
Br J Cancer
, vol.69
, pp. 144-151
-
-
Lohr, M.1
Trautmann, B.2
Gottler, M.3
-
15
-
-
28444499374
-
Extracellular matrix stimulates reactive oxygen species production and increases pancreatic cancer cell survival through 5-lipoxygenase and NADPH oxidase
-
Edderkaoui M, Hong P, Vaquero EC, et al. Extracellular matrix stimulates reactive oxygen species production and increases pancreatic cancer cell survival through 5-lipoxygenase and NADPH oxidase. Am J Physiol 2005; 289: G1137-G1147.
-
(2005)
Am J Physiol
, vol.289
-
-
Edderkaoui, M.1
Hong, P.2
Vaquero, E.C.3
-
16
-
-
0027447152
-
Detection of point mutations in the Kirsten-ras oncogene provides evidence for the multi-centricity of pancreatic carcinoma
-
Motojima K, Urano T, Nagata Y, et al. Detection of point mutations in the Kirsten-ras oncogene provides evidence for the multi-centricity of pancreatic carcinoma. Ann Surg 1993; 217: 138-143.
-
(1993)
Ann Surg
, vol.217
, pp. 138-143
-
-
Motojima, K.1
Urano, T.2
Nagata, Y.3
-
17
-
-
0026338569
-
Distinguishing pancreatic carcinoma from other periampullary carcinomas by analysis of mutations in the Kirsten-ras oncogene
-
Motojima K, Tsunoda T, Kanemastu T, et al. Distinguishing pancreatic carcinoma from other periampullary carcinomas by analysis of mutations in the Kirsten-ras oncogene. Ann Surg 1991; 214: 657-662.
-
(1991)
Ann Surg
, vol.214
, pp. 657-662
-
-
Motojima, K.1
Tsunoda, T.2
Kanemastu, T.3
-
18
-
-
12644290242
-
Analysis of K-ras oncogene mutations in chronic pancreatitis with ductal hyperplasia
-
Rivera J, Werner J, Adrie C, et al. Analysis of K-ras oncogene mutations in chronic pancreatitis; with ductal hyperplasia. Surgery 1997; 121: 42-49.
-
(1997)
Surgery
, vol.121
, pp. 42-49
-
-
Rivera, J.1
Werner, J.2
Adrie, C.3
-
19
-
-
20444464893
-
In vitro modeling of human pancreatic duct epithelial cell transformation defines gene expression changes induced by K-ras oncogenic activation in pancreatic carcinogenesis
-
Qian J, Niu J, Li M, et al. In vitro modeling of human pancreatic duct epithelial cell transformation defines gene expression changes induced by K-ras oncogenic activation in pancreatic carcinogenesis. Cancer Res 2005; 65: 5045-5053.
-
(2005)
Cancer Res
, vol.65
, pp. 5045-5053
-
-
Qian, J.1
Niu, J.2
Li, M.3
-
20
-
-
0345275865
-
Epidermal growth factor receptor autocrine signaling in RIE-1 cells transformed by the ras oncogene enhances radiation resistance
-
Grana TM, Sartor CI, Cox AD. Epidermal growth factor receptor autocrine signaling in RIE-1 cells transformed by the ras oncogene enhances radiation resistance. Cancer Res 2003; 63: 7807-7814.
-
(2003)
Cancer Res
, vol.63
, pp. 7807-7814
-
-
Grana, T.M.1
Sartor, C.I.2
Cox, A.D.3
-
21
-
-
24944573845
-
Pancreatic cancer cell radiation survival and prenyltransferase inhibition: The role of K-ras
-
Brunner TB, Cengel KA, Hahn SM, et al. Pancreatic cancer cell radiation survival and prenyltransferase inhibition: the role of K-ras. Cancer Res 2005; 65: 8433-8441.
-
(2005)
Cancer Res
, vol.65
, pp. 8433-8441
-
-
Brunner, T.B.1
Cengel, K.A.2
Hahn, S.M.3
-
22
-
-
0030980641
-
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
-
Irani K, Xia Y, Zweier J, et al. Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science 1997; 275: 1649-1651.
-
(1997)
Science
, vol.275
, pp. 1649-1651
-
-
Irani, K.1
Xia, Y.2
Zweier, J.3
-
23
-
-
0035901606
-
Opposing functions of Ki-and Ha-Ras genes in the regulation of redox signals
-
Santillo M, Mondola P, Seru R, et al. Opposing functions of Ki-and Ha-Ras genes in the regulation of redox signals. Curr Biol 200; 11: 614-619.
-
(2001)
Curr Biol
, vol.11
, pp. 614-619
-
-
Santillo, M.1
Mondola, P.2
Seru, R.3
-
24
-
-
4544250814
-
Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells
-
Vaquero EC, Edderkaoui M, Pandol SJ, et al. Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells. J Biol Chem 2004; 279: 34643-34654.
-
(2004)
J Biol Chem
, vol.279
, pp. 34643-34654
-
-
Vaquero, E.C.1
Edderkaoui, M.2
Pandol, S.J.3
-
25
-
-
0032732639
-
Superoxide generated in v-Haras-transduced human keratinocyte HaCaT cells
-
Santillo M, Yang JQ, Li SJ, et al. Superoxide generated in v-Haras-transduced human keratinocyte HaCaT cells. Mol Carcinogen 1999; 26: 180-188.
-
(1999)
Mol Carcinogen
, vol.26
, pp. 180-188
-
-
Santillo, M.1
Yang, J.Q.2
Li, S.J.3
-
26
-
-
0032732639
-
Superoxide generation in v-Haras-transduced human keratinocyte HaCaT cells
-
Yang JQ, Li S, Domann F, et al. Superoxide generation in v-Haras-transduced human keratinocyte HaCaT cells. Mol Carcinog 1999; 26: 180-188.
-
(1999)
Mol Carcinog
, vol.26
, pp. 180-188
-
-
Yang, J.Q.1
Li, S.2
Domann, F.3
-
27
-
-
0015056379
-
An enzyme based theory of obligate anaerobiosis: The physiological function of superoxide dismutase
-
McCord J, Keele B, Fridovich I. An enzyme based theory of obligate anaerobiosis: the physiological function of superoxide dismutase. Proc Natl Acad Sci USA 1971; 68: 1024-1027.
-
(1971)
Proc Natl Acad Sci USA
, vol.68
, pp. 1024-1027
-
-
McCord, J.1
Keele, B.2
Fridovich, I.3
-
28
-
-
0018749490
-
Role of superoxide dismutase in cancer: A review
-
Oberley L, Buettner G. Role of superoxide dismutase in cancer: a review. Cancer Res 1979; 39: 1141-1149.
-
(1979)
Cancer Res
, vol.39
, pp. 1141-1149
-
-
Oberley, L.1
Buettner, G.2
-
29
-
-
0000131669
-
Superoxide dismutase and cancer
-
In: Oberley LJ, (Ed). CRC Press
-
Oberley LW. Superoxide dismutase and cancer. In: Oberley LJ, (Ed). Superoxide Dismutase, Vol II. CRC Press. 1982; 125-128.
-
(1982)
Superoxide Dismutase
, vol.2
, pp. 125-128
-
-
Oberley, L.W.1
-
30
-
-
0002975278
-
Oxygen radicals and cancer
-
In: Yu BP, (Ed). CRC Press
-
Oberley TD, Oberley LW. Oxygen radicals and cancer. In: Yu BP, (Ed). Free Radicals in Aging. CRC Press. 1993; 248-267.
-
(1993)
Free Radicals in Aging
, pp. 248-267
-
-
Oberley, T.D.1
Oberley, L.W.2
-
31
-
-
0001989506
-
Reactive oxygen species in the etiology of cancer
-
In: Ioannides C, Lewis DV, (Eds). Prentice Hall
-
Oberley LW, Oberley TD. Reactive oxygen species in the etiology of cancer. In: Ioannides C, Lewis DV, (Eds). Drugs, Diet, and Disease, Vol 1. Prentice Hall. 1994; 49-63.
-
(1994)
Drugs, Diet, and Disease
, vol.1
, pp. 49-63
-
-
Oberley, L.W.1
Oberley, T.D.2
-
32
-
-
0033531247
-
Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells
-
Xu Y, Krishnan A, Wan S, et al. Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells. Oncogene 1999; 18:93-102.
-
(1999)
Oncogene
, vol.18
, pp. 93-102
-
-
Xu, Y.1
Krishnan, A.2
Wan, S.3
-
33
-
-
0027093827
-
Suppression of radiation-induced neoplastic transformation by overexpression of mitochondrial superoxide dismutase
-
St Clair D, Wan X, Oberley T, et al. Suppression of radiation-induced neoplastic transformation by overexpression of mitochondrial superoxide dismutase. Mol Carcinog 1992; 6: 238-242.
-
(1992)
Mol Carcinog
, vol.6
, pp. 238-242
-
-
St Clair, D.1
Wan, X.2
Oberley, T.3
-
34
-
-
0037215312
-
Expression of antioxidant enzymes in diseases of the human pancreas: Another link between chronic pancreatitis and pancreatic cancer
-
Cullen J, Mitros F, Oberley L. Expression of antioxidant enzymes in diseases of the human pancreas: another link between chronic pancreatitis and pancreatic cancer. Pancreas 2003; 26: 23-27.
-
(2003)
Pancreas
, vol.26
, pp. 23-27
-
-
Cullen, J.1
Mitros, F.2
Oberley, L.3
-
35
-
-
0037444154
-
The role of manganese superoxide dismutase in the growth of pancreatic adenocarcinoma
-
Cullen J, Weydert C, Hinkhouse M, et al. The role of manganese superoxide dismutase in the growth of pancreatic adenocarcinoma. Cancer Res 2003; 63: 1297-1303.
-
(2003)
Cancer Res
, vol.63
, pp. 1297-1303
-
-
Cullen, J.1
Weydert, C.2
Hinkhouse, M.3
-
36
-
-
32544436240
-
Metastatic progression of pancreatic cancer: Changes in antioxidant enzymes and cell growth
-
Lewis A, Du, J, Liu J, et al. Metastatic progression of pancreatic cancer: Changes in antioxidant enzymes and cell growth. Clinical and Experimental Metastasis 2006; 22: 523-532.
-
(2006)
Clinical and Experimental Metastasis
, vol.22
, pp. 523-532
-
-
Lewis, A.1
Du, J.2
Liu, J.3
-
37
-
-
0346363268
-
Suppression of the malignant phenotype in human pancreatic cancer cells by the overexpression of manganese superoxide dismutase
-
Weydert C, Roling B, Liu J, et al. Suppression of the malignant phenotype in human pancreatic cancer cells by the overexpression of manganese superoxide dismutase. Mol Cancer Ther 2003; 2: 361-369.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 361-369
-
-
Weydert, C.1
Roling, B.2
Liu, J.3
-
38
-
-
0034660880
-
The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase
-
Li S, Yan T. The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase. Cancer Res 2000; 60: 3927-3939.
-
(2000)
Cancer Res
, vol.60
, pp. 3927-3939
-
-
Li, S.1
Yan, T.2
-
39
-
-
70449174079
-
Glutathione peroxidase, an erythrocyte enzyme that protects hemoglobin from oxidative damage
-
Mills GC. Glutathione peroxidase, an erythrocyte enzyme that protects hemoglobin from oxidative damage. J Biol Chem 1957; 229: 189-197.
-
(1957)
J Biol Chem
, vol.229
, pp. 189-197
-
-
Mills, G.C.1
-
40
-
-
14444271790
-
Mice with homozygous null mutation for the most abundant glutathione peroxidase, GPxl, how increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide
-
Hann J, Bladier C, Griffiths P, et al. Mice with homozygous null mutation for the most abundant glutathione peroxidase, GPxl, how increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide. J Biol Chem 1998; 273: 22528-22536.
-
(1998)
J Biol Chem
, vol.273
, pp. 22528-22536
-
-
Hann, J.1
Bladier, C.2
Griffiths, P.3
-
41
-
-
0025786654
-
Overexpression of seleno-glutathione peroxidase by gene transfer enhances the resistance of T47D human breast cells to clastogenic oxidants
-
Mirault M, Tremblay A, Beaudoin N, et al. Overexpression of seleno-glutathione peroxidase by gene transfer enhances the resistance of T47D human breast cells to clastogenic oxidants. J Biol Chem 1991; 266:20572-20760.
-
(1991)
J Biol Chem
, vol.266
, pp. 20572-20760
-
-
Mirault, M.1
Tremblay, A.2
Beaudoin, N.3
-
42
-
-
0028787356
-
Heterologous expression of selenium-dependent glutathione peroxidase afford cellular resistance to paraquat
-
Kelner M, Bagnell R, Uglik S, et al, Heterologous expression of selenium-dependent glutathione peroxidase afford cellular resistance to paraquat. Arch Biochem Biophys 1995; 323: 40-46.
-
(1995)
Arch Biochem Biophys
, vol.323
, pp. 40-46
-
-
Kelner, M.1
Bagnell, R.2
Uglik, S.3
-
43
-
-
0030834975
-
Glutathione peroxidase protects against peroxynitrite-mediated oxidation
-
Sies H, Sharov V, Klotz L-O, et al. Glutathione peroxidase protects against peroxynitrite-mediated oxidation. J Biol Chem 1997; 272: 27812-27817.
-
(1997)
J Biol Chem
, vol.272
, pp. 27812-27817
-
-
Sies, H.1
Sharov, V.2
Klotz, L.-O.3
-
44
-
-
0027485461
-
S. Bcl-2 functions in an antioxidant pathway to prevent apoptosis
-
Hockenberry D, Oltvai Z, Yin X, et al. S. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993; 75: 241-251.
-
(1993)
Cell
, vol.75
, pp. 241-251
-
-
Hockenberry, D.1
Oltvai, Z.2
Yin, X.3
-
45
-
-
0029925648
-
The protective role of glutathione peroxidase in apoptosis induced by reactive oxygen species
-
Kayanoki Y, Fujii J, Islam K, et al. The protective role of glutathione peroxidase in apoptosis induced by reactive oxygen species. Biochemistry 1996; 119: 817-822.
-
(1996)
Biochemistry
, vol.119
, pp. 817-822
-
-
Kayanoki, Y.1
Fujii, J.2
Islam, K.3
-
46
-
-
30744454042
-
Suppression of the malignant phenotype in pancreatic cancer by the overexpression of phospholipid hydroperoxide glutathione peroxidase (PhGPx)
-
Liu J, Du J, Zhang Y, et al. Suppression of the malignant phenotype in pancreatic cancer by the overexpression of phospholipid. hydroperoxide glutathione peroxidase (PhGPx). Hum Gene Ther 2006; 17: 105-116.
-
(2006)
Hum Gene Ther
, vol.17
, pp. 105-116
-
-
Liu, J.1
Du, J.2
Zhang, Y.3
-
47
-
-
0031225515
-
Phospholipid hydroperoxide glutathione peroxidase (PHGPx): More than an antioxidant enzyme?
-
Ursini F, Maiorino M, Roveri A. Phospholipid hydroperoxide glutathione peroxidase (PHGPx): more than an antioxidant enzyme? Biomed Environ Sci 1997; 10: 327-332.
-
(1997)
Biomed Environ Sci
, vol.10
, pp. 327-332
-
-
Ursini, F.1
Maiorino, M.2
Roveri, A.3
-
48
-
-
0034530537
-
Novel functions of mitochondrial phospholipid hydroperoxide glutathione peroxidase (PhGPx) as an antiapoptotic factor
-
Nakagawa Y, Imai H. Novel functions of mitochondrial phospholipid hydroperoxide glutathione peroxidase (PhGPx) as an antiapoptotic factor. J Health Sci 2000; 46: 414-417.
-
(2000)
J Health Sci
, vol.46
, pp. 414-417
-
-
Nakagawa, Y.1
Imai, H.2
-
49
-
-
0037438730
-
Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells
-
Imai H, Nakagawa Y. Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells. Free Radic Biol Med 2003; 34: 145-169.
-
(2003)
Free Radic Biol Med
, vol.34
, pp. 145-169
-
-
Imai, H.1
Nakagawa, Y.2
-
50
-
-
0025060737
-
Protective action of phospholipid hydroperoxide glutathione peroxidase against membrane-damaging lipid peroxidation. In situ reduction of phospholipid and cholesterol hydroperoxides
-
Thomas JP, Maiorino M, Ursini F, et al. Protective action of phospholipid hydroperoxide glutathione peroxidase against membrane-damaging lipid peroxidation. In situ reduction of phospholipid and cholesterol hydroperoxides. J Biol Chem 1990;265:454-461.
-
(1990)
J Biol Chem
, vol.265
, pp. 454-461
-
-
Thomas, J.P.1
Maiorino, M.2
Ursini, F.3
-
51
-
-
30744454042
-
Suppression of the malignant phenotype in pancreatic cancer by overexpression of the phospholipid hydroperoxide glutathione peroxidase
-
Liu J, Du J, Zhang Y, et al. Suppression of the malignant phenotype in pancreatic cancer by overexpression of the phospholipid hydroperoxide glutathione peroxidase. Hum Gene Ther 2006; 17: 105-116.
-
(2006)
Hum Gene Ther
, vol.17
, pp. 105-116
-
-
Liu, J.1
Du, J.2
Zhang, Y.3
-
52
-
-
30344435321
-
Blocking tumor cell eicosanoid synthesis by GPx4 impedes tumor growth and malignancy
-
Heirman I, Ginneberge E, Brigelius-Flohe R, et al. Blocking tumor cell eicosanoid synthesis by GPx4 impedes tumor growth and malignancy. Free Rad Biol Med 2006; 40: 285-294.
-
(2006)
Free Rad Biol Med
, vol.40
, pp. 285-294
-
-
Heirman, I.1
Ginneberge, E.2
Brigelius-Flohe, R.3
-
53
-
-
0037051715
-
Food-derived polyphenols inhibit pancreatic cancer growth through mitochondrial cytochrome c release and apoptosis
-
Mouria M, Gukovskaya AS, Jung Y, et al. Food-derived polyphenols inhibit pancreatic cancer growth through mitochondrial cytochrome c release and apoptosis. Int J Cancer 2002; 98: 761-769.
-
(2002)
Int J Cancer
, vol.98
, pp. 761-769
-
-
Mouria, M.1
Gukovskaya, A.S.2
Jung, Y.3
|