Adrenal beta-arrestin 1 inhibition in vivo attenuates post-myocardial infarction progression to heart failure and adverse remodeling via reduction of circulating aldosterone levels

Journal of the American College of Cardiology

Volumn 57, Issue 3, 2011, Pages 356-365

  Lymperopoulos, Anastasios ^a,b   Rengo, Giuseppe ^b,d   Zincarelli, Carmela ^b   Kim, Jihee ^c   Koch, Walter J ^b  

^a NOVA SOUTHEASTERN UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d IRCCS   (Italy)

Author keywords

adrenal beta arrestin 1; aldosterone; angiotensin II; heart failure; myocardial infarction

Indexed keywords

ALDOSTERONE; ANGIOTENSIN II; BETA ARRESTIN 1; BETA ARRESTIN 2; G PROTEIN COUPLED RECEPTOR;

ADRENAL CORTEX; ALDOSTERONE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; HEART FAILURE; HEART INFARCTION; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; VIRAL GENE DELIVERY SYSTEM;

ADRENAL GLANDS; ALDOSTERONE; ANIMALS; ARRESTINS; CELL LINE; DISEASE PROGRESSION; GENE TRANSFER TECHNIQUES; HEART FAILURE; HUMANS; LOSARTAN; MYOCARDIAL INFARCTION; RANDOM ALLOCATION; RATS; RECEPTORS, G-PROTEIN-COUPLED; VENTRICULAR REMODELING;

EID: 78651326867     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2010.08.635     Document Type: Article

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