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Volumn 68, Issue 1, 2011, Pages 22-30

Preclinical biomarkers of parkinson disease

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER;

EID: 78651315861     PISSN: 00039942     EISSN: 15383687     Source Type: Journal    
DOI: 10.1001/archneurol.2010.321     Document Type: Review
Times cited : (141)

References (100)
  • 1
    • 64349083816 scopus 로고    scopus 로고
    • Non-motor symptoms of Parkinson's disease: Dopaminergic pathophysiology and treatment
    • Chaudhuri KR, Schapira AH. Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment. Lancet Neurol. 2009;8(5):464-474.
    • (2009) Lancet Neurol , vol.8 , Issue.5 , pp. 464-474
    • Chaudhuri, K.R.1    Schapira, A.H.2
  • 2
    • 60549085946 scopus 로고    scopus 로고
    • Overview of the extranigral aspects of Parkinson disease
    • Lim SY, Fox SH, Lang AE. Overview of the extranigral aspects of Parkinson disease. Arch Neurol. 2009;66(2):167-172.
    • (2009) Arch Neurol , vol.66 , Issue.2 , pp. 167-172
    • Lim, S.Y.1    Fox, S.H.2    Lang, A.E.3
  • 3
    • 41149163183 scopus 로고    scopus 로고
    • Parkinson's disease: Clinical features and diagnosis
    • Jankovic J. Parkinson's disease: clinical features and diagnosis. J Neurol Neurosurg Psychiatry. 2008;79(4):368-376.
    • (2008) J Neurol Neurosurg Psychiatry , vol.79 , Issue.4 , pp. 368-376
    • Jankovic, J.1
  • 4
    • 61949235512 scopus 로고    scopus 로고
    • Diagnosis and the premotor phase of Parkinson disease
    • Tolosa E, Gaig C, Santamaría J, Compta Y. Diagnosis and the premotor phase of Parkinson disease. Neurology. 2009;72(7)(suppl):S12-S20.
    • (2009) Neurology , vol.72 , Issue.7 SUPPL.
    • Tolosa, E.1    Gaig, C.2    Santamaría, J.3    Compta, Y.4
  • 5
    • 33747348188 scopus 로고    scopus 로고
    • Positron emission tomography of monoaminergic vesicular binding in aging and Parkinson disease
    • Bohnen NI, Albin RL, Koeppe RA, et al. Positron emission tomography of monoaminergic vesicular binding in aging and Parkinson disease. J Cereb Blood Flow Metab. 2006;26(9):1198-1212.
    • (2006) J Cereb Blood Flow Metab , vol.26 , Issue.9 , pp. 1198-1212
    • Bohnen, N.I.1    Albin, R.L.2    Koeppe, R.A.3
  • 6
    • 33645749795 scopus 로고    scopus 로고
    • Motor score of the Unified Parkinson Disease Rating Scale as a good predictor of Lewy body-associated neuronal loss in the substantia nigra
    • Greffard S, Verny M, Bonnet AM, et al. Motor score of the Unified Parkinson Disease Rating Scale as a good predictor of Lewy body-associated neuronal loss in the substantia nigra. Arch Neurol. 2006;63(4):584-588.
    • (2006) Arch Neurol , vol.63 , Issue.4 , pp. 584-588
    • Greffard, S.1    Verny, M.2    Bonnet, A.M.3
  • 7
    • 14844300111 scopus 로고    scopus 로고
    • Nonlinear progression of Parkinson disease as determined by serial positron emission tomographic imaging of striatal fluorodopa F 18 activity
    • Hilker R, Schweitzer K, Coburger S, et al. Nonlinear progression of Parkinson disease as determined by serial positron emission tomographic imaging of striatal fluorodopa F 18 activity. Arch Neurol. 2005;62(3):378-382.
    • (2005) Arch Neurol , vol.62 , Issue.3 , pp. 378-382
    • Hilker, R.1    Schweitzer, K.2    Coburger, S.3
  • 8
    • 61949445069 scopus 로고    scopus 로고
    • Can we image premotor Parkinson disease?
    • Marek K, Jennings D. Can we image premotor Parkinson disease? Neurology. 2009;72(7)(suppl):S21-S26.
    • (2009) Neurology , vol.72 , Issue.7 SUPPL.
    • Marek, K.1    Jennings, D.2
  • 9
    • 33746085612 scopus 로고    scopus 로고
    • Preclinical diagnosis of Parkinson's disease: Are we there yet?
    • Siderowf A, Stern MB. Preclinical diagnosis of Parkinson's disease: are we there yet? Curr Neurol Neurosci Rep. 2006;6(4):295-301.
    • (2006) Curr Neurol Neurosci Rep , vol.6 , Issue.4 , pp. 295-301
    • Siderowf, A.1    Stern, M.B.2
  • 10
    • 14844282830 scopus 로고    scopus 로고
    • Progression of Parkinson disease: Are we making progress in charting the course?
    • Jankovic J. Progression of Parkinson disease: are we making progress in charting the course? Arch Neurol. 2005;62(3):351-352.
    • (2005) Arch Neurol , vol.62 , Issue.3 , pp. 351-352
    • Jankovic, J.1
  • 11
    • 57049123693 scopus 로고    scopus 로고
    • The prodromal phase of sporadic Parkinson's disease: Does it exist and if so how long is it?
    • Hawkes CH. The prodromal phase of sporadic Parkinson's disease: does it exist and if so how long is it? Mov Disord. 2008;23(13):1799-1807.
    • (2008) Mov Disord , vol.23 , Issue.13 , pp. 1799-1807
    • Hawkes, C.H.1
  • 12
    • 0032913951 scopus 로고    scopus 로고
    • The role of inheritance in sporadic Parkinson's disease: Evidence from a longitudinal study of dopaminergic function in twins
    • Piccini P, Burn DJ, Ceravolo R, Maraganore D, Brooks DJ. The role of inheritance in sporadic Parkinson's disease: evidence from a longitudinal study of dopaminergic function in twins. Ann Neurol. 1999;45(5):577-582.
    • (1999) Ann Neurol , vol.45 , Issue.5 , pp. 577-582
    • Piccini, P.1    Burn, D.J.2    Ceravolo, R.3    Maraganore, D.4    Brooks, D.J.5
  • 13
    • 0034090879 scopus 로고    scopus 로고
    • Risk for Parkinson's disease: Twin studies for the detection of asymptomatic subjects using [18F]6-fluorodopa PET
    • doi:10.1007/PL00022911
    • Laihinen A, Ruottinen H, Rinne JO, et al. Risk for Parkinson's disease: twin studies for the detection of asymptomatic subjects using [18F]6-fluorodopa PET. J Neurol. 2000;247(suppl 2):II110-II113. doi:10.1007/PL00022911.
    • (2000) J Neurol , vol.247 , Issue.SUPPL. 2
    • Laihinen, A.1    Ruottinen, H.2    Rinne, J.O.3
  • 14
    • 59149101888 scopus 로고    scopus 로고
    • Etiopathogenesis of Parkinson disease: A new beginning?
    • Le W, Chen S, Jankovic J. Etiopathogenesis of Parkinson disease: a new beginning? Neuroscientist. 2009;15(1):28-35.
    • (2009) Neuroscientist , vol.15 , Issue.1 , pp. 28-35
    • Le, W.1    Chen, S.2    Jankovic, J.3
  • 15
    • 32544432029 scopus 로고    scopus 로고
    • Non-motor symptoms of Parkinson's disease: Diagnosis and management
    • National Institute for Clinical Excellence
    • Chaudhuri KR, Healy DG, Schapira AH; National Institute for Clinical Excellence. Non-motor symptoms of Parkinson's disease: diagnosis and management. Lancet Neurol. 2006;5(3):235-245.
    • (2006) Lancet Neurol , vol.5 , Issue.3 , pp. 235-245
    • Chaudhuri, K.R.1    Healy, D.G.2    Schapira, A.H.3
  • 16
    • 58349108478 scopus 로고    scopus 로고
    • Premotor Parkinson's disease: Clinical features, detection, and prospects for treatment
    • doi: 10.1002/ana.21462
    • Siderowf A, Stern MB. Premotor Parkinson's disease: clinical features, detection, and prospects for treatment. Ann Neurol. 2008;64(suppl 2):S139-S147. doi: 10.1002/ana.21462.
    • (2008) Ann Neurol , vol.64 , Issue.SUPPL. 2
    • Siderowf, A.1    Stern, M.B.2
  • 17
    • 34548052479 scopus 로고    scopus 로고
    • Prevalence of essential tremor in patients with Parkinson's disease vs Parkinson-plus syndromes
    • Louis ED, Frucht SJ. Prevalence of essential tremor in patients with Parkinson's disease vs Parkinson-plus syndromes. Mov Disord. 2007;22(10):1402-1407.
    • (2007) Mov Disord , vol.22 , Issue.10 , pp. 1402-1407
    • Louis, E.D.1    Frucht, S.J.2
  • 18
    • 79953287466 scopus 로고    scopus 로고
    • Revisiting the relationship between essential tremor and Parkinson's disease
    • In press
    • Fekete R, Jankovic J. Revisiting the relationship between essential tremor and Parkinson's disease. Mov Disord. In press.
    • Mov Disord
    • Fekete, R.1    Jankovic, J.2
  • 19
    • 36749008470 scopus 로고    scopus 로고
    • Neuropathological changes in essential tremor: 33 cases compared with 21 controls
    • Louis ED, Faust PL, Vonsattel JP, et al. Neuropathological changes in essential tremor: 33 cases compared with 21 controls. Brain. 2007;130(pt 12):3297-3307.
    • (2007) Brain , vol.130 , Issue.PART 12 , pp. 3297-3307
    • Louis, E.D.1    Faust, P.L.2    Vonsattel, J.P.3
  • 20
    • 53149097345 scopus 로고    scopus 로고
    • Emergence of Parkinson's disease in essential tremor: A study of the clinical correlates in 53 patients
    • Minen MT, Louis ED. Emergence of Parkinson's disease in essential tremor: a study of the clinical correlates in 53 patients. Mov Disord. 2008;23(11):1602-1605.
    • (2008) Mov Disord , vol.23 , Issue.11 , pp. 1602-1605
    • Minen, M.T.1    Louis, E.D.2
  • 21
    • 72849150233 scopus 로고    scopus 로고
    • Positive family history of essential tremor influences the motor phenotype of Parkinson's disease
    • Hedera P, Fang JY, Phibbs F, Cooper MK, Charles PD, Davis TL. Positive family history of essential tremor influences the motor phenotype of Parkinson's disease. Mov Disord. 2009;24(15):2285-2288.
    • (2009) Mov Disord , vol.24 , Issue.15 , pp. 2285-2288
    • Hedera, P.1    Fang, J.Y.2    Phibbs, F.3    Cooper, M.K.4    Charles, P.D.5    Davis, T.L.6
  • 22
    • 64749083422 scopus 로고    scopus 로고
    • Risk of incident Parkinson's disease and parkinsonism in essential tremor: A population based study
    • Neurological Disorders in Central Spain Study Group
    • Benito-León J, Louis ED, Bermejo-Pareja F; Neurological Disorders in Central Spain Study Group. Risk of incident Parkinson's disease and parkinsonism in essential tremor: a population based study. J Neurol Neurosurg Psychiatry. 2009;80(4):423-425.
    • (2009) J Neurol Neurosurg Psychiatry , vol.80 , Issue.4 , pp. 423-425
    • Benito-León, J.1    Louis, E.D.2    Bermejo-Pareja, F.3
  • 24
    • 40449083312 scopus 로고    scopus 로고
    • Association of olfactory dysfunction with risk for future Parkinson's disease
    • Ross GW, Petrovitch H, Abbott RD, et al. Association of olfactory dysfunction with risk for future Parkinson's disease. Ann Neurol. 2008;63(2):167-173.
    • (2008) Ann Neurol , vol.63 , Issue.2 , pp. 167-173
    • Ross, G.W.1    Petrovitch, H.2    Abbott, R.D.3
  • 25
    • 67650361399 scopus 로고    scopus 로고
    • The use of a color coded probability scale to interpret smell tests in suspected parkinsonism
    • Silveira-Moriyama L, Petrie A, Williams DR, et al. The use of a color coded probability scale to interpret smell tests in suspected parkinsonism. Mov Disord. 2009;24(8):1144-1153.
    • (2009) Mov Disord , vol.24 , Issue.8 , pp. 1144-1153
    • Silveira-Moriyama, L.1    Petrie, A.2    Williams, D.R.3
  • 26
    • 55749107827 scopus 로고    scopus 로고
    • Biomarkers to detect central dopamine deficiency and distinguish Parkinson disease from multiple system atrophy
    • Goldstein DS, Holmes C, Bentho O, et al. Biomarkers to detect central dopamine deficiency and distinguish Parkinson disease from multiple system atrophy. Parkinsonism Relat Disord. 2008;14(8):600-607.
    • (2008) Parkinsonism Relat Disord , vol.14 , Issue.8 , pp. 600-607
    • Goldstein, D.S.1    Holmes, C.2    Bentho, O.3
  • 27
    • 67651160628 scopus 로고    scopus 로고
    • Biopsies of olfactory epithelium in patients with Parkinson's disease
    • Witt M, Bormann K, Gudziol V, et al. Biopsies of olfactory epithelium in patients with Parkinson's disease. Mov Disord. 2009;24(6):906-914.
    • (2009) Mov Disord , vol.24 , Issue.6 , pp. 906-914
    • Witt, M.1    Bormann, K.2    Gudziol, V.3
  • 28
    • 62649128032 scopus 로고    scopus 로고
    • Sleep disorders and daytime sleepiness in Parkinson's disease
    • Monderer R, Thorpy M. Sleep disorders and daytime sleepiness in Parkinson's disease. Curr Neurol Neurosci Rep. 2009;9(2):173-180.
    • (2009) Curr Neurol Neurosci Rep , vol.9 , Issue.2 , pp. 173-180
    • Monderer, R.1    Thorpy, M.2
  • 30
    • 69249126529 scopus 로고    scopus 로고
    • Mild cognitive impairment in rapid eye movement sleep behavior disorder and Parkinson's disease
    • Gagnon JF, Vendette M, Postuma RB, et al. Mild cognitive impairment in rapid eye movement sleep behavior disorder and Parkinson's disease. Ann Neurol. 2009;66(1):39-47.
    • (2009) Ann Neurol , vol.66 , Issue.1 , pp. 39-47
    • Gagnon, J.F.1    Vendette, M.2    Postuma, R.B.3
  • 31
    • 53149134978 scopus 로고    scopus 로고
    • Manifestations of Parkinson disease differ in association with REM sleep behavior disorder
    • Postuma RB, Gagnon JF, Vendette M, Charland K, Montplaisir J. Manifestations of Parkinson disease differ in association with REM sleep behavior disorder. Mov Disord. 2008;23(12):1665-1672.
    • (2008) Mov Disord , vol.23 , Issue.12 , pp. 1665-1672
    • Postuma, R.B.1    Gagnon, J.F.2    Vendette, M.3    Charland, K.4    Montplaisir, J.5
  • 32
    • 33748341694 scopus 로고    scopus 로고
    • Saccadic latency distributions in Parkinson's disease and the effects of L-dopa
    • Michell AW, Xu Z, Fritz D, et al. Saccadic latency distributions in Parkinson's disease and the effects of L-dopa. Exp Brain Res. 2006;174(1):7-18.
    • (2006) Exp Brain Res , vol.174 , Issue.1 , pp. 7-18
    • Michell, A.W.1    Xu, Z.2    Fritz, D.3
  • 33
    • 67650712202 scopus 로고    scopus 로고
    • Multiple step pattern as a biomarker in Parkinson disease
    • Blekher T, Weaver M, Rupp J, et al. Multiple step pattern as a biomarker in Parkinson disease. Parkinsonism Relat Disord. 2009;15(7):506-510.
    • (2009) Parkinsonism Relat Disord , vol.15 , Issue.7 , pp. 506-510
    • Blekher, T.1    Weaver, M.2    Rupp, J.3
  • 34
    • 67651183933 scopus 로고    scopus 로고
    • Dysautonomia rating scales in Parkinson's disease: Sialorrhea, dysphagia, and constipation: Critique and recommendations by movement disorders task force on rating scales for Parkinson's disease
    • Evatt ML, Chaudhuri KR, Chou KL, et al. Dysautonomia rating scales in Parkinson's disease: sialorrhea, dysphagia, and constipation: critique and recommendations by movement disorders task force on rating scales for Parkinson's disease. Mov Disord. 2009;24(5):635-646.
    • (2009) Mov Disord , vol.24 , Issue.5 , pp. 635-646
    • Evatt, M.L.1    Chaudhuri, K.R.2    Chou, K.L.3
  • 35
    • 71849100691 scopus 로고    scopus 로고
    • Treatment of dysautonomia associated with Parkinson's disease
    • Mostile G, Jankovic J. Treatment of dysautonomia associated with Parkinson's disease. Parkinsonism Relat Disord. 2009;15(suppl 3):S224-S232.
    • (2009) Parkinsonism Relat Disord , vol.15 , Issue.SUPPL. 3
    • Mostile, G.1    Jankovic, J.2
  • 37
    • 67849094320 scopus 로고    scopus 로고
    • The spectrum of neuropsychiatric symptoms in patients with early untreated Parkinson's disease
    • Aarsland D, Brønnick K, Alves G, et al. The spectrum of neuropsychiatric symptoms in patients with early untreated Parkinson's disease. J Neurol Neurosurg Psychiatry. 2009;80(8):928-930.
    • (2009) J Neurol Neurosurg Psychiatry , vol.80 , Issue.8 , pp. 928-930
    • Aarsland, D.1    Brønnick, K.2    Alves, G.3
  • 38
    • 69549110511 scopus 로고    scopus 로고
    • The course of depressive symptoms in early Parkinson's disease
    • Ravina B, Elm J, Camicioli R, et al. The course of depressive symptoms in early Parkinson's disease. Mov Disord. 2009;24(9):1306-1311.
    • (2009) Mov Disord , vol.24 , Issue.9 , pp. 1306-1311
    • Ravina, B.1    Elm, J.2    Camicioli, R.3
  • 39
    • 34547639700 scopus 로고    scopus 로고
    • The impact of depressive symptoms in early Parkinson disease
    • Ravina B, Camicioli R, Como PG, et al. The impact of depressive symptoms in early Parkinson disease. Neurology. 2007;69(4):342-347.
    • (2007) Neurology , vol.69 , Issue.4 , pp. 342-347
    • Ravina, B.1    Camicioli, R.2    Como, P.G.3
  • 40
    • 33748340878 scopus 로고    scopus 로고
    • What is the evidence for a premorbid parkinsonian personality: A systematic review
    • Ishihara L, Brayne C. What is the evidence for a premorbid parkinsonian personality: a systematic review. Mov Disord. 2006;21(8):1066-1072.
    • (2006) Mov Disord , vol.21 , Issue.8 , pp. 1066-1072
    • Ishihara, L.1    Brayne, C.2
  • 41
    • 33644499473 scopus 로고    scopus 로고
    • Relationship between impulsive sensation seeking traits, smoking, alcohol and caffeine intake, and Parkinson's disease
    • Evans AH, Lawrence AD, Potts J, et al. Relationship between impulsive sensation seeking traits, smoking, alcohol and caffeine intake, and Parkinson's disease. J Neurol Neurosurg Psychiatry. 2006;77(3):317-321.
    • (2006) J Neurol Neurosurg Psychiatry , vol.77 , Issue.3 , pp. 317-321
    • Evans, A.H.1    Lawrence, A.D.2    Potts, J.3
  • 43
    • 66549101869 scopus 로고    scopus 로고
    • Do parkinsonian patients have trouble telling lies? the neurobiological basis of deceptive behaviour
    • Abe N, Fujii T, Hirayama K, et al. Do parkinsonian patients have trouble telling lies? the neurobiological basis of deceptive behaviour. Brain. 2009;132(pt 5):1386-1395.
    • (2009) Brain , vol.132 , Issue.PART 5 , pp. 1386-1395
    • Abe, N.1    Fujii, T.2    Hirayama, K.3
  • 45
    • 57749095477 scopus 로고    scopus 로고
    • A critical evaluation of the Braak staging scheme for Parkinson's disease
    • Burke RE, Dauer WT, Vonsattel JP. A critical evaluation of the Braak staging scheme for Parkinson's disease. Ann Neurol. 2008;64(5):485-491.
    • (2008) Ann Neurol , vol.64 , Issue.5 , pp. 485-491
    • Burke, R.E.1    Dauer, W.T.2    Vonsattel, J.P.3
  • 46
    • 61949220753 scopus 로고    scopus 로고
    • The Parkinson chimera
    • Lees AJ. The Parkinson chimera. Neurology. 2009;72(7)(suppl):S2-S11.
    • (2009) Neurology , vol.72 , Issue.7 SUPPL.
    • Lees, A.J.1
  • 47
    • 42549125030 scopus 로고    scopus 로고
    • The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease: A critical analysis of α-synuclein staging
    • Kalaitzakis ME, Graeber MB, Gentleman SM, Pearce RK. The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease: a critical analysis of α-synuclein staging. Neuropathol Appl Neurobiol. 2008;34(3):284-295.
    • (2008) Neuropathol Appl Neurobiol , vol.34 , Issue.3 , pp. 284-295
    • Kalaitzakis, M.E.1    Graeber, M.B.2    Gentleman, S.M.3    Pearce, R.K.4
  • 48
    • 41149115508 scopus 로고    scopus 로고
    • Evidence that incidental Lewy body disease is pre-symptomatic Parkinson's disease
    • Dickson DW, Fujishiro H, DelleDonne A, et al. Evidence that incidental Lewy body disease is pre-symptomatic Parkinson's disease. Acta Neuropathol. 2008;115(4):437-444.
    • (2008) Acta Neuropathol , vol.115 , Issue.4 , pp. 437-444
    • Dickson, D.W.1    Fujishiro, H.2    DelleDonne, A.3
  • 49
    • 41149141259 scopus 로고    scopus 로고
    • Applicability of current staging/categorization of α-synuclein pathology and their clinical relevance
    • Parkkinen L, Pirttilä T, Alafuzoff I. Applicability of current staging/categorization of α-synuclein pathology and their clinical relevance. Acta Neuropathol. 2008;115(4):399-407.
    • (2008) Acta Neuropathol , vol.115 , Issue.4 , pp. 399-407
    • Parkkinen, L.1    Pirttilä, T.2    Alafuzoff, I.3
  • 50
    • 47749147444 scopus 로고    scopus 로고
    • The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease
    • Attems J, Jellinger KA. The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease. Neuropathol Appl Neurobiol. 2008;34(4):466-467.
    • (2008) Neuropathol Appl Neurobiol , vol.34 , Issue.4 , pp. 466-467
    • Attems, J.1    Jellinger, K.A.2
  • 51
    • 69149088365 scopus 로고    scopus 로고
    • Is Parkinson's disease a prion disorder?
    • Olanow CW, Prusiner SB. Is Parkinson's disease a prion disorder? Proc Natl Acad Sci U S A. 2009;106(31):12571-12572.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.31 , pp. 12571-12572
    • Olanow, C.W.1    Prusiner, S.B.2
  • 52
    • 49449097043 scopus 로고    scopus 로고
    • Incidental Lewy body disease and preclinical Parkinson disease
    • DelleDonne A, Klos KJ, Fujishiro H, et al. Incidental Lewy body disease and preclinical Parkinson disease. Arch Neurol. 2008;65(8):1074-1080.
    • (2008) Arch Neurol , vol.65 , Issue.8 , pp. 1074-1080
    • DelleDonne, A.1    Klos, K.J.2    Fujishiro, H.3
  • 54
    • 41049097524 scopus 로고    scopus 로고
    • New insights into the pathology of Parkinson's disease: Does the peripheral autonomic system become central?
    • Probst A, Bloch A, Tolnay M. New insights into the pathology of Parkinson's disease: does the peripheral autonomic system become central? Eur J Neurol. 2008;15(suppl 1):1-4.
    • (2008) Eur J Neurol , vol.15 , Issue.SUPPL. 1 , pp. 1-4
    • Probst, A.1    Bloch, A.2    Tolnay, M.3
  • 55
    • 34249907298 scopus 로고    scopus 로고
    • Do α-synuclein aggregates in autonomic plexuses predate Lewy body disorders? a cohort study
    • Minguez-Castellanos A, Chamorro CE, Escamilla-Sevilla F, et al. Do α-synuclein aggregates in autonomic plexuses predate Lewy body disorders? a cohort study. Neurology. 2007;68(23):2012-2018.
    • (2007) Neurology , vol.68 , Issue.23 , pp. 2012-2018
    • Minguez-Castellanos, A.1    Chamorro, C.E.2    Escamilla-Sevilla, F.3
  • 56
    • 34347222580 scopus 로고    scopus 로고
    • Myocardial sympathetic degeneration correlates with clinical phenotype of Parkinson's disease
    • Spiegel J, Hellwig D, Farmakis G, et al. Myocardial sympathetic degeneration correlates with clinical phenotype of Parkinson's disease. Mov Disord. 2007;22(7):1004-1008.
    • (2007) Mov Disord , vol.22 , Issue.7 , pp. 1004-1008
    • Spiegel, J.1    Hellwig, D.2    Farmakis, G.3
  • 57
    • 19344366060 scopus 로고    scopus 로고
    • Skin and platelet α-synuclein as peripheral biomarkers of Parkinson's disease
    • Michell AW, Luheshi LM, Barker RA. Skin and platelet α-synuclein as peripheral biomarkers of Parkinson's disease. Neurosci Lett. 2005;381(3):294-298.
    • (2005) Neurosci Lett , vol.381 , Issue.3 , pp. 294-298
    • Michell, A.W.1    Luheshi, L.M.2    Barker, R.A.3
  • 58
    • 77149178728 scopus 로고    scopus 로고
    • α-Synuclein accumulation in skin nerve fibers revealed by skin biopsy in pure autonomic failure
    • Shishido T, Ikemura M, Obi T, et al. α-Synuclein accumulation in skin nerve fibers revealed by skin biopsy in pure autonomic failure. Neurology. 2010;74(7):608-610.
    • (2010) Neurology , vol.74 , Issue.7 , pp. 608-610
    • Shishido, T.1    Ikemura, M.2    Obi, T.3
  • 59
    • 58349108690 scopus 로고    scopus 로고
    • Biomarkers for Parkinson's disease: Tools to assess Parkinson's disease onset and progression
    • published correction appears in Ann Neurol. 2009;65(2):232
    • Marek K, Jennings D, Tamagnan G, Seibyl J. Biomarkers for Parkinson's disease: tools to assess Parkinson's disease onset and progression [published correction appears in Ann Neurol. 2009;65(2):232]. Ann Neurol. 2008;64(suppl 2):S111-S121.
    • (2008) Ann Neurol , vol.64 , Issue.SUPPL. 2
    • Marek, K.1    Jennings, D.2    Tamagnan, G.3    Seibyl, J.4
  • 60
    • 67449123263 scopus 로고    scopus 로고
    • High-resolution diffusion tensor imaging in the substantia nigra of de novo Parkinson disease
    • Vaillancourt DE, Spraker MB, Prodoehl J, et al. High-resolution diffusion tensor imaging in the substantia nigra of de novo Parkinson disease. Neurology. 2009;72(16):1378-1384.
    • (2009) Neurology , vol.72 , Issue.16 , pp. 1378-1384
    • Vaillancourt, D.E.1    Spraker, M.B.2    Prodoehl, J.3
  • 61
    • 38949140887 scopus 로고    scopus 로고
    • Positron emission tomography in premotor Parkinson's disease
    • Stoessl AJ. Positron emission tomography in premotor Parkinson's disease. Parkinsonism Relat Disord. 2007;13(suppl 3):S421-S424.
    • (2007) Parkinsonism Relat Disord , vol.13 , Issue.SUPPL. 3
    • Stoessl, A.J.1
  • 62
    • 38949184973 scopus 로고    scopus 로고
    • SPECT imaging of the dopaminergic system in (premotor) Parkinson's disease
    • Booij J, Knol RJ. SPECT imaging of the dopaminergic system in (premotor) Parkinson's disease. Parkinsonism Relat Disord. 2007;13(suppl 3):S425-S428.
    • (2007) Parkinsonism Relat Disord , vol.13 , Issue.SUPPL. 3
    • Booij, J.1    Knol, R.J.2
  • 63
    • 77951234348 scopus 로고    scopus 로고
    • Distinguishing SWEDDs patients with asymmetric resting tremor from Parkinson's disease: A clinical and electrophysiological study
    • Schwingenschuh P, Ruge D, Edwards MJ, et al. Distinguishing SWEDDs patients with asymmetric resting tremor from Parkinson's disease: a clinical and electrophysiological study. Mov Disord. 2010;25(5):560-569.
    • (2010) Mov Disord , vol.25 , Issue.5 , pp. 560-569
    • Schwingenschuh, P.1    Ruge, D.2    Edwards, M.J.3
  • 64
    • 45049086823 scopus 로고    scopus 로고
    • A voxel-based PET study of dopamine transporters in Parkinson's disease: Relevance of age at onset
    • Panzacchi A, Moresco RM, Garibotto V, et al. A voxel-based PET study of dopamine transporters in Parkinson's disease: relevance of age at onset. Neurobiol Dis. 2008;31(1):102-109.
    • (2008) Neurobiol Dis , vol.31 , Issue.1 , pp. 102-109
    • Panzacchi, A.1    Moresco, R.M.2    Garibotto, V.3
  • 65
    • 27844547163 scopus 로고    scopus 로고
    • In vivo detection of iron and neuromelanin by transcranial sonography: A new approach for early detection of substantia nigra damage
    • Zecca L, Berg D, Arzberger T, et al. In vivo detection of iron and neuromelanin by transcranial sonography: a new approach for early detection of substantia nigra damage. Mov Disord. 2005;20(10):1278-1285.
    • (2005) Mov Disord , vol.20 , Issue.10 , pp. 1278-1285
    • Zecca, L.1    Berg, D.2    Arzberger, T.3
  • 66
    • 53649086350 scopus 로고    scopus 로고
    • Transcranial sonography in movement disorders
    • Berg D, Godau J, Walter U. Transcranial sonography in movement disorders. Lancet Neurol. 2008;7(11):1044-1055.
    • (2008) Lancet Neurol , vol.7 , Issue.11 , pp. 1044-1055
    • Berg, D.1    Godau, J.2    Walter, U.3
  • 67
    • 42049123661 scopus 로고    scopus 로고
    • Midbrain iron content in early Parkinson disease: A potential biomarker of disease status
    • Martin WR, Wieler M, Gee M. Midbrain iron content in early Parkinson disease: a potential biomarker of disease status. Neurology. 2008;70(16, pt 2):1411-1417.
    • (2008) Neurology , vol.70 , Issue.16 PART 2 , pp. 1411-1417
    • Martin, W.R.1    Wieler, M.2    Gee, M.3
  • 68
    • 58149242840 scopus 로고    scopus 로고
    • Progression of dopaminergic dysfunction in a LRRK2 kindred: A multitracer PET study
    • Nandhagopal R, Mak E, Schulzer M, et al. Progression of dopaminergic dysfunction in a LRRK2 kindred: a multitracer PET study. Neurology. 2008;71(22):1790-1795.
    • (2008) Neurology , vol.71 , Issue.22 , pp. 1790-1795
    • Nandhagopal, R.1    Mak, E.2    Schulzer, M.3
  • 69
    • 65549111767 scopus 로고    scopus 로고
    • Neurochemical approaches in the laboratory diagnosis of Parkinson and Parkinson dementia syndromes: A review
    • Jesse S, Steinacker P, Lehnert S, Gillardon F, Hengerer B, Otto M. Neurochemical approaches in the laboratory diagnosis of Parkinson and Parkinson dementia syndromes: a review. CNS Neurosci Ther. 2009;15(2):157-182.
    • (2009) CNS Neurosci Ther , vol.15 , Issue.2 , pp. 157-182
    • Jesse, S.1    Steinacker, P.2    Lehnert, S.3    Gillardon, F.4    Hengerer, B.5    Otto, M.6
  • 70
    • 69849083033 scopus 로고    scopus 로고
    • Neurochemical biomarkers in the differential diagnosis of movement disorders
    • Mollenhauer B, Trenkwalder C. Neurochemical biomarkers in the differential diagnosis of movement disorders. Mov Disord. 2009;24(10):1411-1426.
    • (2009) Mov Disord , vol.24 , Issue.10 , pp. 1411-1426
    • Mollenhauer, B.1    Trenkwalder, C.2
  • 71
    • 61949269129 scopus 로고    scopus 로고
    • Genomic and proteomic biomarkers for Parkinson disease
    • Gasser T. Genomic and proteomic biomarkers for Parkinson disease. Neurology. 2009;72(7)(suppl):S27-S31.
    • (2009) Neurology , vol.72 , Issue.7 SUPPL.
    • Gasser, T.1
  • 72
    • 79953283868 scopus 로고    scopus 로고
    • Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression
    • In press. doi:10.1002/ana.22311
    • Shi M, Bradner J, Hancock AM, et al. Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression. Ann Neurol. In press. doi:10.1002/ana.22311.
    • Ann Neurol
    • Shi, M.1    Bradner, J.2    Hancock, A.M.3
  • 73
    • 77950223687 scopus 로고    scopus 로고
    • DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease
    • Hong Z, Shi M, Chung KA, et al. DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease. Brain. 2010;133(pt 3):713-726.
    • (2010) Brain , vol.133 , Issue.PART 3 , pp. 713-726
    • Hong, Z.1    Shi, M.2    Chung, K.A.3
  • 74
    • 77957241703 scopus 로고    scopus 로고
    • Biomarkers of PD progression: Is CSF the answer?
    • Aarsland D, Ravina B. Biomarkers of PD progression: is CSF the answer? Neurology. 2010;75(12):1036-1037.
    • (2010) Neurology , vol.75 , Issue.12 , pp. 1036-1037
    • Aarsland, D.1    Ravina, B.2
  • 75
    • 77950535153 scopus 로고    scopus 로고
    • Lymphomonocyte α-synuclein levels in aging and in Parkinson disease
    • Brighina L, Prigione A, Begni B, et al. Lymphomonocyte α-synuclein levels in aging and in Parkinson disease. Neurobiol Aging. 2010;31(5):884-885.
    • (2010) Neurobiol Aging , vol.31 , Issue.5 , pp. 884-885
    • Brighina, L.1    Prigione, A.2    Begni, B.3
  • 76
    • 33947619003 scopus 로고    scopus 로고
    • Plasma α-synuclein is decreased in subjects with Parkinson's disease
    • Li QX, Mok SS, Laughton KM, et al. Plasma α-synuclein is decreased in subjects with Parkinson's disease. Exp Neurol. 2007;204(2):583-588.
    • (2007) Exp Neurol , vol.204 , Issue.2 , pp. 583-588
    • Li, Q.X.1    Mok, S.S.2    Laughton, K.M.3
  • 77
    • 37749020081 scopus 로고    scopus 로고
    • Functional imaging of the cerebral olfactory system in patients with Parkinson's disease
    • Westermann B, Wattendorf E, Schwerdtfeger U, et al. Functional imaging of the cerebral olfactory system in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry. 2008;79(1):19-24.
    • (2008) J Neurol Neurosurg Psychiatry , vol.79 , Issue.1 , pp. 19-24
    • Westermann, B.1    Wattendorf, E.2    Schwerdtfeger, U.3
  • 78
    • 73549111772 scopus 로고    scopus 로고
    • Urate as a predictor of the rate of clinical decline in Parkinson disease
    • Parkinson Study Group DATATOP Investigators
    • Ascherio A, LeWitt PA, Xu K, et al; Parkinson Study Group DATATOP Investigators. Urate as a predictor of the rate of clinical decline in Parkinson disease. Arch Neurol. 2009;66(12):1460-1468.
    • (2009) Arch Neurol , vol.66 , Issue.12 , pp. 1460-1468
    • Ascherio, A.1    LeWitt, P.A.2    Xu, K.3
  • 79
    • 50149097574 scopus 로고    scopus 로고
    • Decreased NURR1 gene expression in patients with Parkinson's disease
    • Le W, Pan T, Huang M, et al. Decreased NURR1 gene expression in patients with Parkinson's disease. J Neurol Sci. 2008;273(1-2):29-33.
    • (2008) J Neurol Sci , vol.273 , Issue.1-2 , pp. 29-33
    • Le, W.1    Pan, T.2    Huang, M.3
  • 80
    • 33846465545 scopus 로고    scopus 로고
    • Molecular markers of early Parkinson's disease based on gene expression in blood
    • Scherzer CR, Eklund AC, Morse LJ, et al. Molecular markers of early Parkinson's disease based on gene expression in blood. Proc Natl Acad Sci U S A. 2007;104(3):955-960.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.3 , pp. 955-960
    • Scherzer, C.R.1    Eklund, A.C.2    Morse, L.J.3
  • 81
    • 38849159145 scopus 로고    scopus 로고
    • Metabolomic profiling to develop blood biomarkers for Parkinson's disease
    • Bogdanov M, Matson WR, Wang L, et al. Metabolomic profiling to develop blood biomarkers for Parkinson's disease. Brain. 2008;131(pt 2):389-396.
    • (2008) Brain , vol.131 , Issue.PART 2 , pp. 389-396
    • Bogdanov, M.1    Matson, W.R.2    Wang, L.3
  • 82
    • 73849150680 scopus 로고    scopus 로고
    • Glycoproteomics in neurodegenerative diseases
    • Hwang H, Zhang J, Chung KA, et al. Glycoproteomics in neurodegenerative diseases. Mass Spectrom Rev. 2010;29(1):79-125.
    • (2010) Mass Spectrom Rev , vol.29 , Issue.1 , pp. 79-125
    • Hwang, H.1    Zhang, J.2    Chung, K.A.3
  • 83
    • 67049134827 scopus 로고    scopus 로고
    • Metabolomics tools for identifying biomarkers for neuropsychiatric diseases
    • Quinones MP, Kaddurah-Daouk R. Metabolomics tools for identifying biomarkers for neuropsychiatric diseases. Neurobiol Dis. 2009;35(2):165-176.
    • (2009) Neurobiol Dis , vol.35 , Issue.2 , pp. 165-176
    • Quinones, M.P.1    Kaddurah-Daouk, R.2
  • 84
    • 48249113010 scopus 로고    scopus 로고
    • Spectroscopy of human plasma for diagnosis of idiopathic Parkinson's disease
    • Schipper HM, Kwok CS, Rosendahl SM, et al. Spectroscopy of human plasma for diagnosis of idiopathic Parkinson's disease. Biomark Med. 2008;2(3):229-238.
    • (2008) Biomark Med , vol.2 , Issue.3 , pp. 229-238
    • Schipper, H.M.1    Kwok, C.S.2    Rosendahl, S.M.3
  • 85
    • 41249098565 scopus 로고    scopus 로고
    • RNA biomarkers of Parkinson's disease: Developing tool for new therapies
    • Hennecke G, Scherzer CR. RNA biomarkers of Parkinson's disease: developing tool for new therapies. Biomarkers Med. 2008;2(1):41-53.
    • (2008) Biomarkers Med , vol.2 , Issue.1 , pp. 41-53
    • Hennecke, G.1    Scherzer, C.R.2
  • 86
    • 31344439221 scopus 로고    scopus 로고
    • LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews
    • Ozelius LJ, Senthil G, Saunders-Pullman R, et al. LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews. N Engl J Med. 2006;354(4):424-425.
    • (2006) N Engl J Med , vol.354 , Issue.4 , pp. 424-425
    • Ozelius, L.J.1    Senthil, G.2    Saunders-Pullman, R.3
  • 87
    • 31344432937 scopus 로고    scopus 로고
    • LRRK2 G2019S as a cause of Parkinson's disease in North African Arabs
    • French Parkinson's Disease Genetics Study Group
    • Lesage S, Dürr A, Tazir M, et al; French Parkinson's Disease Genetics Study Group. LRRK2 G2019S as a cause of Parkinson's disease in North African Arabs. N Engl J Med. 2006;354(4):422-423.
    • (2006) N Engl J Med , vol.354 , Issue.4 , pp. 422-423
    • Lesage, S.1    Dürr, A.2    Tazir, M.3
  • 88
    • 42949119345 scopus 로고    scopus 로고
    • CSF multianalyte profile distinguishes Alzheimer and Parkinson diseases
    • Zhang J, Sokal I, Peskind ER, et al. CSF multianalyte profile distinguishes Alzheimer and Parkinson diseases. Am J Clin Pathol. 2008;129(4):526-529.
    • (2008) Am J Clin Pathol , vol.129 , Issue.4 , pp. 526-529
    • Zhang, J.1    Sokal, I.2    Peskind, E.R.3
  • 89
    • 73349125417 scopus 로고    scopus 로고
    • Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other humanmalignancies
    • Veeriah S, Taylor BS, Meng S, et al. Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other humanmalignancies. Nat Genet. 2010;42(1):77-82.
    • (2010) Nat Genet , vol.42 , Issue.1 , pp. 77-82
    • Veeriah, S.1    Taylor, B.S.2    Meng, S.3
  • 90
    • 33847067038 scopus 로고    scopus 로고
    • A functional polymorphism in the parkin gene promoter affects the age of onset of Parkinson's disease
    • Sutherland G, Mellick G, Sue C, et al. A functional polymorphism in the parkin gene promoter affects the age of onset of Parkinson's disease. Neurosci Lett. 2007;414(2):170-173.
    • (2007) Neurosci Lett , vol.414 , Issue.2 , pp. 170-173
    • Sutherland, G.1    Mellick, G.2    Sue, C.3
  • 92
    • 45149122797 scopus 로고    scopus 로고
    • Serum urate as a predictor of clinical and radiographic progression in Parkinson disease
    • Parkinson Study Group PRECEPT Investigators
    • Schwarzschild MA, Schwid SR, Marek K, et al; Parkinson Study Group PRECEPT Investigators. Serum urate as a predictor of clinical and radiographic progression in Parkinson disease. Arch Neurol. 2008;65(6):716-723.
    • (2008) Arch Neurol , vol.65 , Issue.6 , pp. 716-723
    • Schwarzschild, M.A.1    Schwid, S.R.2    Marek, K.3
  • 93
    • 45149089053 scopus 로고    scopus 로고
    • Serum uric acid and clinical progression in Parkinson disease: Potential biomarker for nigrostriatal failure
    • Schiess M, Oh I. Serum uric acid and clinical progression in Parkinson disease: potential biomarker for nigrostriatal failure. Arch Neurol. 2008;65(6):698-699.
    • (2008) Arch Neurol , vol.65 , Issue.6 , pp. 698-699
    • Schiess, M.1    Oh, I.2
  • 94
    • 37549057265 scopus 로고    scopus 로고
    • Peripheral inflammatory biomarkers and risk of Parkinson's disease
    • Chen H, O'Reilly EJ, Schwarzschild MA, Ascherio A. Peripheral inflammatory biomarkers and risk of Parkinson's disease. Am J Epidemiol. 2008;167(1):90-95.
    • (2008) Am J Epidemiol , vol.167 , Issue.1 , pp. 90-95
    • Chen, H.1    O'Reilly, E.J.2    Schwarzschild, M.A.3    Ascherio, A.4
  • 95
    • 64549093797 scopus 로고    scopus 로고
    • Circulating interleukin-10 and interleukin- 12 in Parkinson's disease
    • Rentzos M, Nikolaou C, Andreadou E, et al. Circulating interleukin-10 and interleukin- 12 in Parkinson's disease. Acta Neurol Scand. 2009;119(5):332-337.
    • (2009) Acta Neurol Scand , vol.119 , Issue.5 , pp. 332-337
    • Rentzos, M.1    Nikolaou, C.2    Andreadou, E.3
  • 96
    • 49249129009 scopus 로고    scopus 로고
    • Low LDL cholesterol and increased risk of Parkinson's disease: Prospective results from Honolulu- Asia Aging Study
    • Huang X, Abbott RD, Petrovitch H, Mailman RB, Ross GW. Low LDL cholesterol and increased risk of Parkinson's disease: prospective results from Honolulu- Asia Aging Study. Mov Disord. 2008;23(7):1013-1018.
    • (2008) Mov Disord , vol.23 , Issue.7 , pp. 1013-1018
    • Huang, X.1    Abbott, R.D.2    Petrovitch, H.3    Mailman, R.B.4    Ross, G.W.5
  • 97
    • 60849127578 scopus 로고    scopus 로고
    • Genetic determinants of hair color and Parkinson's disease risk
    • Gao X, Simon KC, Han J, Schwarzschild MA, Ascherio A. Genetic determinants of hair color and Parkinson's disease risk. Ann Neurol. 2009;65(1):76-82.
    • (2009) Ann Neurol , vol.65 , Issue.1 , pp. 76-82
    • Gao, X.1    Simon, K.C.2    Han, J.3    Schwarzschild, M.A.4    Ascherio, A.5
  • 98
    • 77956210946 scopus 로고    scopus 로고
    • Biomarkers: Casting the net wide
    • Jones R. Biomarkers: casting the net wide. Nature. 2010;466(7310):S11- S12.
    • (2010) Nature , vol.466 , Issue.7310
    • Jones, R.1
  • 99
  • 100
    • 77954954518 scopus 로고    scopus 로고
    • Diagnostic cerebrospinal fluid biomarkers for Parkinson's disease: A pathogenetically based approach
    • van Dijk KD, Teunissen CE, Drukarch B, et al. Diagnostic cerebrospinal fluid biomarkers for Parkinson's disease: a pathogenetically based approach. Neurobiol Dis. 2010;39(3):229-241.
    • (2010) Neurobiol Dis , vol.39 , Issue.3 , pp. 229-241
    • Van Dijk, K.D.1    Teunissen, C.E.2    Drukarch, B.3


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