Prodrugs of aza nucleosides based on proton transfer reaction

Journal of Computer-Aided Molecular Design

Volumn 24, Issue 12, 2010, Pages 961-970

  Karaman, Rafik ^a  

^a NONE

Author keywords

Aza nucleosides prodrugs; Decitabine prodrugs; DFT calculations; Effective molarity (EM); Kirby's enzyme model; Proton transfer reaction

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; NUCLEOSIDE DERIVATIVE; PRODRUG;

ARTICLE; CHEMICAL MODEL; CONFORMATIONAL TRANSITION; CONTROLLED RELEASE FORMULATION; DFT CALCULATION; DRUG ABSORPTION; DRUG DOSAGE FORM; DRUG STRUCTURE; HYDROGEN BOND; HYDROPHILICITY; KIRBY ENZYME MODEL; MATHEMATICAL PARAMETERS; PRIORITY JOURNAL; PROTON TRANSPORT;

ANTIMETABOLITES, ANTINEOPLASTIC; AZACITIDINE; CYTARABINE; DRUG DESIGN; HYDROGEN BONDING; KINETICS; MYELODYSPLASTIC SYNDROMES; NUCLEOSIDES; PRODRUGS; PROTONS; THERMODYNAMICS;

EID: 78651287394     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-010-9389-6     Document Type: Article

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