메뉴 건너뛰기




Volumn 214, Issue 1, 2011, Pages 147-161

A diverse family of novel peptide toxins from an unusual cone snail, Conus californicus

Author keywords

Conotoxins; Peptides; Peptidomics; Sodium channels

Indexed keywords

MOLLUSC VENOM; PEPTIDE; PRIMER DNA; SODIUM CHANNEL BLOCKING AGENT;

EID: 78651284974     PISSN: 00220949     EISSN: None     Source Type: Journal    
DOI: 10.1242/jeb.046086     Document Type: Article
Times cited : (26)

References (71)
  • 2
    • 0034557759 scopus 로고    scopus 로고
    • Phylogenetic relationships among loliginid squids (Cephalopoda: Myopsida) based on analyses of multiple data sets
    • Anderson, F. E. (2000). Phylogenetic relationships among loliginid squids (Cephalopoda: Myopsida) based on analyses of multiple data sets. Zool. J. Linn. Soc. 130, 603-633.
    • (2000) Zool. J. Linn. Soc. , vol.130 , pp. 603-633
    • Anderson, F.E.1
  • 4
    • 29344443859 scopus 로고    scopus 로고
    • Conotoxins and the posttranslational modification of secreted gene products
    • Buczek, O., Bulaj, G. and Olivera, B. M. (2005). Conotoxins and the posttranslational modification of secreted gene products. Cell. Mol. Life Sci. 62, 3067-3079.
    • (2005) Cell. Mol. Life Sci. , vol.62 , pp. 3067-3079
    • Buczek, O.1    Bulaj, G.2    Olivera, B.M.3
  • 5
    • 0033565832 scopus 로고    scopus 로고
    • Role of accurate mass measurement (+/- 10 ppm) in protein identification strategies employing MS or MS/MS and database searching
    • Clauser, K. R., Baker, P. and Burlingame, A. L. (1999). Role of accurate mass measurement (+/- 10 ppm) in protein identification strategies employing MS or MS/MS and database searching. Anal. Chem. 71, 2871-2882.
    • (1999) Anal. Chem. , vol.71 , pp. 2871-2882
    • Clauser, K.R.1    Baker, P.2    Burlingame, A.L.3
  • 7
    • 0015298014 scopus 로고
    • Proceedings: Active factors in the venom duct of Conus californicus
    • Cottrell, G. A. and Twarog, B. M. (1972). Proceedings: active factors in the venom duct of Conus californicus. Br. J. Pharmacol. 44, 365P-366P.
    • (1972) Br. J. Pharmacol. , vol.44
    • Cottrell, G.A.1    Twarog, B.M.2
  • 8
    • 15444344863 scopus 로고    scopus 로고
    • A novel posttranslational modification involving bromination of tryptophan. Identification of the residue, L-6-bromotryptophan, in peptides from Conus imperialis and Conus radiatus venom
    • Craig, A. G., Jimenez, E. C., Dykert, J., Nielsen, D. B., Gulyas, J., Abogadie, F. C., Porter, J., Rivier, J. E., Cruz, L. J., Olivera, B. M. et al. (1997). A novel posttranslational modification involving bromination of tryptophan. Identification of the residue, L-6-bromotryptophan, in peptides from Conus imperialis and Conus radiatus venom. J. Biol. Chem. 272, 4689-4698.
    • (1997) J. Biol. Chem. , vol.272 , pp. 4689-4698
    • Craig, A.G.1    Jimenez, E.C.2    Dykert, J.3    Nielsen, D.B.4    Gulyas, J.5    Abogadie, F.C.6    Porter, J.7    Rivier, J.E.8    Cruz, L.J.9    Olivera, B.M.10
  • 9
    • 0033198875 scopus 로고    scopus 로고
    • Post-translationally modified neuropeptides from Conus venoms
    • Craig, A. G., Bandyopadhyay, P. and Olivera, B. M. (1999). Post-translationally modified neuropeptides from Conus venoms. Eur. J. Biochem. 264, 271-275.
    • (1999) Eur. J. Biochem. , vol.264 , pp. 271-275
    • Craig, A.G.1    Bandyopadhyay, P.2    Olivera, B.M.3
  • 10
    • 33745199727 scopus 로고    scopus 로고
    • Novel gamma-carboxyglutamic acid-containing peptides from the venom of Conus textile
    • Czerwiec, E., Kalume, D. E., Roepstorff, P., Hambe, B., Furie, B., Furie, B. C. and Stenflo, J. (2006). Novel gamma-carboxyglutamic acid-containing peptides from the venom of Conus textile. FEBS Lett. 273, 2779-2788.
    • (2006) FEBS Lett. , vol.273 , pp. 2779-2788
    • Czerwiec, E.1    Kalume, D.E.2    Roepstorff, P.3    Hambe, B.4    Furie, B.5    Furie, B.C.6    Stenflo, J.7
  • 11
    • 2942554865 scopus 로고    scopus 로고
    • Structures of μO-conotoxins from Conus marmoreus. Inhibitors of tetrodotoxin (TTX)-senstitive and TTX-resistant sodium channles in mammalian sensory nerurons
    • Daly, N. L., Ekberg, J. A., Thomas, L., Adams, D. J., Lewis, R. J. and Craik, D. J. (2004). Structures of μO-conotoxins from Conus marmoreus. Inhibitors of tetrodotoxin (TTX)-senstitive and TTX-resistant sodium channles in mammalian sensory nerurons. J. Biol. Chem. 279, 25774-25782.
    • (2004) J. Biol. Chem. , vol.279 , pp. 25774-25782
    • Daly, N.L.1    Ekberg, J.A.2    Thomas, L.3    Adams, D.J.4    Lewis, R.J.5    Craik, D.J.6
  • 12
    • 51749083941 scopus 로고    scopus 로고
    • Differentiation of venoms of predatory marine gastropods: Divergence of orthologous toxin genes of closely related Conus species with different dietary specializations
    • Duda, T. F., Jr (2008). Differentiation of venoms of predatory marine gastropods: divergence of orthologous toxin genes of closely related Conus species with different dietary specializations. J. Mol. Evol. 67, 315-321.
    • (2008) J. Mol. Evol. , vol.67 , pp. 315-321
    • Duda Jr., T.F.1
  • 13
    • 11144273961 scopus 로고    scopus 로고
    • Species-level phylogeography and evolutionary history of the hyperdiverse marine gastropod genus Conus
    • Duda, T. F., Jr and Kohn, A. J. (2005). Species-level phylogeography and evolutionary history of the hyperdiverse marine gastropod genus Conus. Mol. Phylogenet. Evol. 34, 257-272.
    • (2005) Mol. Phylogenet. Evol. , vol.34 , pp. 257-272
    • Duda Jr., T.F.1    Kohn, A.J.2
  • 14
    • 66249109989 scopus 로고    scopus 로고
    • Ecological release and venom evolution of a predatory marine snail at Easter Island
    • Duda, T. F., Jr and Lee, T. (2009). Ecological release and venom evolution of a predatory marine snail at Easter Island. PLoS ONE 4, e5558.
    • (2009) PLoS ONE , vol.4
    • Duda Jr., T.F.1    Lee, T.2
  • 15
    • 13044283060 scopus 로고    scopus 로고
    • Molecular genetics of ecological diversification: Duplication and rapid evolution of toxin genes of the venomous gastropod Conus
    • Duda, T. F., Jr and Palumbi, S. R. (1999). Molecular genetics of ecological diversification: duplication and rapid evolution of toxin genes of the venomous gastropod Conus. Proc. Natl. Acad. Sci. USA 96, 6820-6823.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 6820-6823
    • Duda Jr., T.F.1    Palumbi, S.R.2
  • 16
    • 0033863707 scopus 로고    scopus 로고
    • Evolutionary diversification of multigene families: Allelic selection of toxins in predatory cone snails
    • Duda, T. F., Jr and Palumbi, S. R. (2000). Evolutionary diversification of multigene families: allelic selection of toxins in predatory cone snails. Mol. Biol. Evol. 17, 1286-1293.
    • (2000) Mol. Biol. Evol. , vol.17 , pp. 1286-1293
    • Duda Jr., T.F.1    Palumbi, S.R.2
  • 17
    • 2942612546 scopus 로고    scopus 로고
    • Gene expression and feeding ecology: Evolution of piscivory in the venomous gastropod genus Conus
    • Duda, T. F., Jr and Palumbi, S. R. (2004). Gene expression and feeding ecology: evolution of piscivory in the venomous gastropod genus Conus. Proc. Biol. Sci. 271, 1165-1174.
    • (2004) Proc. Biol. Sci. , vol.271 , pp. 1165-1174
    • Duda Jr., T.F.1    Palumbi, S.R.2
  • 18
    • 0034901513 scopus 로고    scopus 로고
    • Origins of diverse feeding ecologies within Conus, a geuns of venomous marine gastropods
    • Duda, T. F., Jr, Kohn, A. J. and Palumbi, S. R. (2001). Origins of diverse feeding ecologies within Conus, a geuns of venomous marine gastropods. Biol. J. Linn. Soc. Lond. 73, 391-409.
    • (2001) Biol. J. Linn. Soc. Lond. , vol.73 , pp. 391-409
    • Duda Jr., T.F.1    Kohn, A.J.2    Palumbi, S.R.3
  • 19
    • 67650921409 scopus 로고    scopus 로고
    • Geographic variation in venom allelic composition and diets of the widespread predatory marine gastropod Conus ebraeus
    • Duda, T. F., Jr, Chang, D., Lewis, B. D. and Lee, T. (2009). Geographic variation in venom allelic composition and diets of the widespread predatory marine gastropod Conus ebraeus. PLoS ONE 4, e6245.
    • (2009) PLoS ONE , vol.4
    • Duda Jr., T.F.1    Chang, D.2    Lewis, B.D.3    Lee, T.4
  • 20
    • 48249132363 scopus 로고    scopus 로고
    • Conotoxin modulation of voltagegated sodium channels
    • Ekberg, J., Craik, D. J. and Adams, D. J. (2008). Conotoxin modulation of voltagegated sodium channels. Int. J. Biochem. Cell Biol. 40, 2363-2368.
    • (2008) Int. J. Biochem. Cell. Biol. , vol.40 , pp. 2363-2368
    • Ekberg, J.1    Craik, D.J.2    Adams, D.J.3
  • 21
    • 0018077566 scopus 로고
    • Cholinergic receptor in Aplysia neurons: Activation by a venom component from the marine snail Conus californicus
    • Elliott, E. J. and Kehoe, J. (1978). Cholinergic receptor in Aplysia neurons: activation by a venom component from the marine snail Conus californicus. Brain Res. 156, 387-390.
    • (1978) Brain Res. , vol.156 , pp. 387-390
    • Elliott, E.J.1    Kehoe, J.2
  • 22
    • 0018770212 scopus 로고
    • Venom of marine snail Conus californicus: Biochemical studies of a cholinomimetic component
    • Elliott, E. J. and Raftery, M. A. (1979). Venom of marine snail Conus californicus: biochemical studies of a cholinomimetic component. Toxicon 17, 259-268.
    • (1979) Toxicon , vol.17 , pp. 259-268
    • Elliott, E.J.1    Raftery, M.A.2
  • 24
    • 0034798344 scopus 로고    scopus 로고
    • Venomous cone snails: Molecular phylogeny and the generation of toxin diversity
    • Espiritu, D. J., Watkins, M., Dia-Monje, V., Cartier, G. E., Cruz, L. J. and Olivera, B. M. (2001). Venomous cone snails: molecular phylogeny and the generation of toxin diversity. Toxicon 39, 1899-1916.
    • (2001) Toxicon , vol.39 , pp. 1899-1916
    • Espiritu, D.J.1    Watkins, M.2    Dia-Monje, V.3    Cartier, G.E.4    Cruz, L.J.5    Olivera, B.M.6
  • 25
    • 0035184148 scopus 로고    scopus 로고
    • Potassium channels: From scorpion venoms to high-resolution structure
    • Garcia, M. L., Gao, Y., McManus, O. B. and Kaczorowski, G. J. (2001). Potassium channels: from scorpion venoms to high-resolution structure. Toxicon 39, 739-748.
    • (2001) Toxicon , vol.39 , pp. 739-748
    • Garcia, M.L.1    Gao, Y.2    McManus, O.B.3    Kaczorowski, G.J.4
  • 26
    • 0025223340 scopus 로고
    • Control of the spatial distribution of sodium channels in giant fiber lobe neurons of the squid
    • Gilly, W. F., Lucero, M. T. and Horrigan, F. T. (1990). Control of the spatial distribution of sodium channels in giant fiber lobe neurons of the squid. Neuron 5, 663-674.
    • (1990) Neuron , vol.5 , pp. 663-674
    • Gilly, W.F.1    Lucero, M.T.2    Horrigan, F.T.3
  • 27
    • 0030977971 scopus 로고    scopus 로고
    • Fast and slow activation kinetics of voltage-gated sodium channels in molluscan neurons
    • Gilly, W. F., Gillette, R. and McFarlane, M. (1997). Fast and slow activation kinetics of voltage-gated sodium channels in molluscan neurons. J. Neurophysiol. 77, 2373-2384.
    • (1997) J. Neurophysiol. , vol.77 , pp. 2373-2384
    • Gilly, W.F.1    Gillette, R.2    McFarlane, M.3
  • 28
    • 0036338783 scopus 로고    scopus 로고
    • Evolution of voltage-gated Na (+) channels
    • Goldin, A. L. (2002). Evolution of voltage-gated Na (+) channels. J. Exp. Biol. 205, 575-584.
    • (2002) J. Exp. Biol. , vol.205 , pp. 575-584
    • Goldin, A.L.1
  • 30
    • 0023924234 scopus 로고
    • Peptide toxins from venomous Conus snails
    • Gray, W. R., Olivera, B. M. and Cruz, L. J. (1988). Peptide toxins from venomous Conus snails. Annu. Rev. Biochem. 57, 665-700.
    • (1988) Annu. Rev. Biochem. , vol.57 , pp. 665-700
    • Gray, W.R.1    Olivera, B.M.2    Cruz, L.J.3
  • 31
    • 0030051784 scopus 로고    scopus 로고
    • Agitoxin footprinting the shaker potassium channel pore
    • Gross, A. and MacKinnon, R. (1996). Agitoxin footprinting the shaker potassium channel pore. Neuron 16, 399-406.
    • (1996) Neuron , vol.16 , pp. 399-406
    • Gross, A.1    MacKinnon, R.2
  • 32
    • 67649592405 scopus 로고    scopus 로고
    • Conotoxins: Natural product drug leads
    • Halai, R. and Craik, D. J. (2009). Conotoxins: natural product drug leads. Nat. Prod. Rep. 26, 526-536.
    • (2009) Nat. Prod. Rep. , vol.26 , pp. 526-536
    • Halai, R.1    Craik, D.J.2
  • 33
    • 2942605083 scopus 로고    scopus 로고
    • Isolation and characterization of three novel Gla-containing Conus marmoreus venom peptides, one with a novel cysteine pattern
    • Hansson, K., Furie, B., Furie, B. C. and Stenflo, J. (2004). Isolation and characterization of three novel Gla-containing Conus marmoreus venom peptides, one with a novel cysteine pattern. Biochem. Biophys. Res. Commun. 319, 1081-1087.
    • (2004) Biochem. Biophys. Res. Commun. , vol.319 , pp. 1081-1087
    • Hansson, K.1    Furie, B.2    Furie, B.C.3    Stenflo, J.4
  • 34
    • 34250017052 scopus 로고    scopus 로고
    • Conotoxins of the O-superfamily affecting voltage-gated sodium channels
    • Heinemann, S. H. and Leipold, E. (2007). Conotoxins of the O-superfamily affecting voltage-gated sodium channels. Cell. Mol. Life Sci. 64, 1329-1340.
    • (2007) Cell. Mol. Life Sci. , vol.64 , pp. 1329-1340
    • Heinemann, S.H.1    Leipold, E.2
  • 36
    • 8644274099 scopus 로고    scopus 로고
    • Sequencing and mass profiling highly modified conotoxins using global reduction/alkylation followed by mass spectrometry
    • Jakubowski, J. A. and Sweedler, J. V. (2004). Sequencing and mass profiling highly modified conotoxins using global reduction/alkylation followed by mass spectrometry. Anal. Chem. 76, 6541-6547.
    • (2004) Anal. Chem. , vol.76 , pp. 6541-6547
    • Jakubowski, J.A.1    Sweedler, J.V.2
  • 37
  • 38
    • 33646134111 scopus 로고    scopus 로고
    • Screening for posttranslational modifications in conotoxins using liquid chromatography/mass spectrometry: An important component of conotoxin discovery
    • Jakubowski, J. A., Kelley, W. P. and Sweedler, J. V. (2006). Screening for posttranslational modifications in conotoxins using liquid chromatography/mass spectrometry: an important component of conotoxin discovery. Toxicon 47, 688-699.
    • (2006) Toxicon , vol.47 , pp. 688-699
    • Jakubowski, J.A.1    Kelley, W.P.2    Sweedler, J.V.3
  • 41
    • 12344317094 scopus 로고    scopus 로고
    • Direct cDNA cloning of novel conopeptide precursors of the O-superfamily
    • Kauferstein, S., Melaun, C. and Mebs, D. (2005). Direct cDNA cloning of novel conopeptide precursors of the O-superfamily. Peptides 26, 361-367.
    • (2005) Peptides , vol.26 , pp. 361-367
    • Kauferstein, S.1    Melaun, C.2    Mebs, D.3
  • 42
    • 0000318474 scopus 로고
    • Food specialization in Conus in Hawaii and California
    • Kohn, A. J. (1966). Food specialization in Conus in Hawaii and California. Ecology 47, 1041-1043.
    • (1966) Ecology , vol.47 , pp. 1041-1043
    • Kohn, A.J.1
  • 43
    • 0000751796 scopus 로고    scopus 로고
    • Superfamily Conidae
    • ed. P. L. Beesley, G. J. B. Ross and A. Wells, Melbourne: CSIRO Publishing
    • Kohn, A. J. (1998). Superfamily Conidae. In Mollusca: The Southern Synthesis. Part B. Fauna of Australia, Vol. 5 (ed. P. L. Beesley, G. J. B. Ross and A. Wells), pp. 846-854. Melbourne: CSIRO Publishing.
    • (1998) Mollusca: The Southern Synthesis. Part B. Fauna of Australia , vol.5 , pp. 846-854
    • Kohn, A.J.1
  • 46
    • 0037338365 scopus 로고    scopus 로고
    • Proteomic analysis of post-translational modifications
    • Mann, M. and Jensen, O. N. (2003). Proteomic analysis of post-translational modifications. Nat. Biotechnol. 21, 255-261.
    • (2003) Nat. Biotechnol. , vol.21 , pp. 255-261
    • Mann, M.1    Jensen, O.N.2
  • 47
    • 0030893730 scopus 로고    scopus 로고
    • Fast inactivation of delayed rectifier K conductance in squid giant axon and its cell bodies
    • Mathes, C., Rosenthal, J. J., Armstrong, C. M. and Gilly, W. F. (1997). Fast inactivation of delayed rectifier K conductance in squid giant axon and its cell bodies. J. Gen. Physiol. 109, 435-448.
    • (1997) J. Gen. Physiol. , vol.109 , pp. 435-448
    • Mathes, C.1    Rosenthal, J.J.2    Armstrong, C.M.3    Gilly, W.F.4
  • 48
    • 0029943275 scopus 로고    scopus 로고
    • Spatial localization of calcium channels in giant fiber lobe neurons of the squid (Loligo opalescens)
    • McFarlane, M. B. and Gilly, W. F. (1996). Spatial localization of calcium channels in giant fiber lobe neurons of the squid (Loligo opalescens). Proc. Natl. Acad. Sci. USA 93, 5067-5071.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5067-5071
    • McFarlane, M.B.1    Gilly, W.F.2
  • 49
    • 0034894357 scopus 로고    scopus 로고
    • Cone venom - From accidental stings to deliberate injection
    • McIntosh, J. M. and Jones, R. M. (2001). Cone venom - from accidental stings to deliberate injection. Toxicon 39, 1447-1451.
    • (2001) Toxicon , vol.39 , pp. 1447-1451
    • McIntosh, J.M.1    Jones, R.M.2
  • 52
    • 0028983387 scopus 로고
    • The charybdotoxin family of K+ channel-blocking peptides
    • Miller, C. (1995). The charybdotoxin family of K+ channel-blocking peptides. Neuron 15, 5-10.
    • (1995) Neuron , vol.15 , pp. 5-10
    • Miller, C.1
  • 54
    • 33751049816 scopus 로고    scopus 로고
    • Conotoxins down under
    • Norton, R. S. and Olivera, B. M. (2006). Conotoxins down under. Toxicon 48, 780-798.
    • (2006) Toxicon , vol.48 , pp. 780-798
    • Norton, R.S.1    Olivera, B.M.2
  • 55
    • 0030729069 scopus 로고    scopus 로고
    • E. E. Just Lecture, 1996. Conus venom peptides, receptor and ion channel targets, and drug design: 50 million years of neuropharmacology
    • Olivera, B. M. (1997). E. E. Just Lecture, 1996. Conus venom peptides, receptor and ion channel targets, and drug design: 50 million years of neuropharmacology. Mol. Biol. Cell 8, 2101-2109.
    • (1997) Mol. Biol. Cell. , vol.8 , pp. 2101-2109
    • Olivera, B.M.1
  • 56
    • 0035239229 scopus 로고    scopus 로고
    • Conotoxins, in retrospect
    • Olivera, B. M. and Cruz, L. J. (2001). Conotoxins, in retrospect. Toxicon 39, 7-14.
    • (2001) Toxicon , vol.39 , pp. 7-14
    • Olivera, B.M.1    Cruz, L.J.2
  • 58
    • 33751118759 scopus 로고    scopus 로고
    • Diversity and evolution of conotoxins based on gene expression profiling of Conus litteratus
    • Pi, C., Liu, J., Peng, C., Liu, Y., Jiang, X., Zhao, Y., Tang, S., Wang, L., Dong, M., Chen, S. et al. (2006). Diversity and evolution of conotoxins based on gene expression profiling of Conus litteratus. Genomics 88, 809-819.
    • (2006) Genomics , vol.88 , pp. 809-819
    • Pi, C.1    Liu, J.2    Peng, C.3    Liu, Y.4    Jiang, X.5    Zhao, Y.6    Tang, S.7    Wang, L.8    Dong, M.9    Chen, S.10
  • 59
    • 77649179582 scopus 로고    scopus 로고
    • Evolution of Conus peptide genes: Duplication and positive selection in the A-superfamily
    • Puillandre, N., Watkins, M. and Olivera, B. M. (2010). Evolution of Conus peptide genes: duplication and positive selection in the A-superfamily. J. Mol. Evol. 70, 190-202.
    • (2010) J. Mol. Evol. , vol.70 , pp. 190-202
    • Puillandre, N.1    Watkins, M.2    Olivera, B.M.3
  • 61
    • 0141798612 scopus 로고    scopus 로고
    • Identified ion channels in the squid nervous system
    • Rosenthal, J. J. and Gilly, W. F. (2003). Identified ion channels in the squid nervous system. Neurosignals 12, 126-141.
    • (2003) Neurosignals , vol.12 , pp. 126-141
    • Rosenthal, J.J.1    Gilly, W.F.2
  • 63
    • 0003087476 scopus 로고
    • Megafauna of the upper miocene castaic formation, Los Angeles county, California
    • Stanton, R. J. (1966). Megafauna of the upper miocene castaic formation, Los Angeles county, California. J. Paleontol. 40, 21-40.
    • (1966) J. Paleontol , vol.40 , pp. 21-40
    • Stanton, R.J.1
  • 64
    • 0037115526 scopus 로고    scopus 로고
    • Analysis of bromotryptophan and hydroxyproline modifications by high-resolution, high-accuracy precursor ion scanning utilizing fragment ions with mass-deficient mass tags
    • Steen, H. and Mann, M. (2002). Analysis of bromotryptophan and hydroxyproline modifications by high-resolution, high-accuracy precursor ion scanning utilizing fragment ions with mass-deficient mass tags. Anal. Chem. 74, 6230-6236.
    • (2002) Anal. Chem. , vol.74 , pp. 6230-6236
    • Steen, H.1    Mann, M.2
  • 65
    • 27844589454 scopus 로고    scopus 로고
    • Piscivorous behavior of a temperate cone snail, Conus californicus
    • Stewart, J. and Gilly, W. F. (2005). Piscivorous behavior of a temperate cone snail, Conus californicus. Biol. Bull. 209, 146-153.
    • (2005) Biol. Bull. , vol.209 , pp. 146-153
    • Stewart, J.1    Gilly, W.F.2
  • 66
    • 0347989461 scopus 로고    scopus 로고
    • Conus venoms: A rich source of novel ion channel-targeted peptides
    • Terlau, H. and Olivera, B. M. (2004). Conus venoms: a rich source of novel ion channel-targeted peptides. Physiol. Rev. 84, 41-68.
    • (2004) Physiol. Rev. , vol.84 , pp. 41-68
    • Terlau, H.1    Olivera, B.M.2
  • 67
    • 28044453479 scopus 로고    scopus 로고
    • Effects of delta-conotoxins PVIA and SVIE on sodium channels in the amphibian sympathetic nervous system
    • West, P. J., Bulaj, G. and Yoshikami, D. (2005). Effects of delta-conotoxins PVIA and SVIE on sodium channels in the amphibian sympathetic nervous system. J. Neurophysiol. 94, 3916-3924.
    • (2005) J. Neurophysiol. , vol.94 , pp. 3916-3924
    • West, P.J.1    Bulaj, G.2    Yoshikami, D.3
  • 68
    • 0012163647 scopus 로고
    • Studies on the venom of the marine snail Conus californicus
    • Whysner, J. A. and Saunders, P. R. (1963). Studies on the venom of the marine snail Conus californicus. Toxicon 1, 113-122.
    • (1963) Toxicon , vol.1 , pp. 113-122
    • Whysner, J.A.1    Saunders, P.R.2
  • 69
    • 0013972137 scopus 로고
    • Purification of the lethal fraction of the venom of the marine snail Conus californicus
    • Whysner, J. A. and Saunders, P. R. (1966). Purification of the lethal fraction of the venom of the marine snail Conus californicus. Toxicon 4, 177-181.
    • (1966) Toxicon , vol.4 , pp. 177-181
    • Whysner, J.A.1    Saunders, P.R.2
  • 70
    • 0025342986 scopus 로고
    • Constant and hypervariable regions in conotoxin propeptides
    • Woodward, S. R., Cruz, L. J., Olivera, B. M. and Hillyard, D. R. (1990). Constant and hypervariable regions in conotoxin propeptides. EMBO J. 9, 1015-1020.
    • (1990) EMBO J. , vol.9 , pp. 1015-1020
    • Woodward, S.R.1    Cruz, L.J.2    Olivera, B.M.3    Hillyard, D.R.4
  • 71
    • 32344433189 scopus 로고    scopus 로고
    • The μO-conotoxin MrVIA inhibits voltage-gated sodium channels by associating with domain-3
    • Zorn, S., Leipold, E., Hansel, A., Bulaj, G., Olivera, B. M., Terlau, H. and Heinemann, S. H. (2006). The μO-conotoxin MrVIA inhibits voltage-gated sodium channels by associating with domain-3. FEBS Lett. 580, 1360-1364.
    • (2006) FEBS Lett. , vol.580 , pp. 1360-1364
    • Zorn, S.1    Leipold, E.2    Hansel, A.3    Bulaj, G.4    Olivera, B.M.5    Terlau, H.6    Heinemann, S.H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.