메뉴 건너뛰기




Volumn 26, Issue 6, 2010, Pages 1029-1040

Blocking type i interferon (IFN) signaling impairs antigen responsiveness of circulating lymphocytes and alters their homing to lymphoid organs: Protective role of type i IFN

Author keywords

Anti IFNR1; Apoptosis; B Lymphocytes; Lymphoid Tissues; Proliferation; T Lymphocytes; Type I IFN

Indexed keywords

INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 7; MITOGENIC AGENT;

EID: 78651260887     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000323978     Document Type: Article
Times cited : (8)

References (49)
  • 1
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JFR, Wyllie AH, Currie AR: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972;26:239-257.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Jfr, K.1    Wyllie, A.H.2    Currie, A.R.3
  • 3
    • 0031784094 scopus 로고    scopus 로고
    • The process of ultrastructural changes from nuclei to apoptotic body
    • Ihara T, Yamamoto T, Sugamata, M, Okumura H, Ueno Y: The process of ultrastructural changes from nuclei to apoptotic body. Virchows Arch 1998;433:443-447.
    • (1998) Virchows Arch , vol.433 , pp. 443-447
    • Ihara, T.1    Yamamoto, T.2    Sugamata, M.3    Okumura, H.4    Ueno, Y.5
  • 4
    • 33745984210 scopus 로고    scopus 로고
    • Abnormal lymphoid organ development in immunodeficient mutant mice
    • Seymour R, Sundberg J P, Hogenesch H: Abnormal lymphoid organ development in immunodeficient mutant mice. Vet Pathol 2006;43:401-423.
    • (2006) Vet Pathol , vol.43 , pp. 401-423
    • Seymour, R.1    Sundberg, J.P.2    Hogenesch, H.3
  • 6
    • 3042733286 scopus 로고    scopus 로고
    • Elucidating the functional anatomy of secondary lymphoid organs
    • Pabst O, Herbrand H, Bernhardt G, Förster R: Elucidating the functional anatomy of secondary lymphoid organs. Curr Opin Immunol 2004;16:394-399.
    • (2004) Curr Opin Immunol , vol.16 , pp. 394-399
    • Pabst, O.1    Herbrand, H.2    Bernhardt, G.3    Förster, R.4
  • 8
    • 28244459495 scopus 로고    scopus 로고
    • Massive Apoptosis in Lymphoid Organs in Animal Models for Primary and Secondary Progressive Multiple Sclerosis
    • Tsunoda I, Libbey JE, Kuang LQ, Terry EJ, Fujinami RS: Massive Apoptosis in Lymphoid Organs in Animal Models for Primary and Secondary Progressive Multiple Sclerosis. Am J Pathol 2005;167:1631-1646.
    • (2005) Am J Pathol , vol.167 , pp. 1631-1646
    • Tsunoda, I.1    Libbey, J.E.2    Kuang, L.Q.3    Terry, E.J.4    Fujinami, R.S.5
  • 10
    • 0030889207 scopus 로고    scopus 로고
    • The IFN gamma receptor: A paradigm for cytokine receptor signaling
    • Bach, EA, Aguet M, Schreiber RD: The IFN gamma receptor: a paradigm for cytokine receptor signaling. Annu Rev Immunol 1997;15:563-591.
    • (1997) Annu Rev Immunol , vol.15 , pp. 563-591
    • Bach, E.A.1    Aguet, M.2    Schreiber, R.D.3
  • 11
    • 0032996486 scopus 로고    scopus 로고
    • The Jak-STAT pathway: Cytokine signaling from the receptor to the nucleus
    • Heim MH: The Jak-STAT pathway: cytokine signaling from the receptor to the nucleus. J Receptor Signal Transduc Res 1999;19:75-120.
    • (1999) J Receptor Signal Transduc Res , vol.19 , pp. 75-120
    • Heim, M.H.1
  • 12
    • 0036399552 scopus 로고    scopus 로고
    • Interferon-alpha-receptor interactions: A complex story unfolding
    • Deonarain R, Chan DC, Platanias LC, Fish EN: Interferon-alpha-receptor interactions: A complex story unfolding. Curr Pharm Des 2002;8:2131-2137.
    • (2002) Curr Pharm des , vol.8 , pp. 2131-2137
    • Deonarain, R.1    Chan, D.C.2    Platanias, L.C.3    Fish, E.N.4
  • 13
    • 4143062575 scopus 로고    scopus 로고
    • Ligand-induced assembling of the type i interferon receptor on supported lipid bilayers
    • Lamken P, Lata S, Gavutis M, Piehler J: Ligand-induced assembling of the type I interferon receptor on supported lipid bilayers. J Mol Biol 2004;341:303-318.
    • (2004) J Mol Biol , vol.341 , pp. 303-318
    • Lamken, P.1    Lata, S.2    Gavutis, M.3    Piehler, J.4
  • 14
    • 69949120819 scopus 로고    scopus 로고
    • Palmitoylation of interferon-alpha (IFN-alpha) receptor subunit IFNAR1 is required for the activation of Stat1 and Stat2 by IFN-alpha
    • Claudinon J, Gonnord P, Beslard E, Marchetti M, Mitchell K, Boularan C, Johannes L, Eid P, Lamaze C: Palmitoylation of interferon-alpha (IFN-alpha) receptor subunit IFNAR1 is required for the activation of Stat1 and Stat2 by IFN-alpha. J Biol Chem 2009;284:24328-24340.
    • (2009) J Biol Chem , vol.284 , pp. 24328-24340
    • Claudinon, J.1    Gonnord, P.2    Beslard, E.3    Marchetti, M.4    Mitchell, K.5    Boularan, C.6    Johannes, L.7    Eid, P.8    Lamaze, C.9
  • 16
    • 77952546595 scopus 로고    scopus 로고
    • Type i interferon (IFN-alpha/ beta) rescues B-lymphocytes from apoptosis via PI3Kdelta/Akt, Rho-A, NFkappaB and Bcl-2/Bcl(XL)
    • Badr G, Saad H, Waly H, Hassan K, Abdel-Tawab H: Type I interferon (IFN-alpha/ beta) rescues B-lymphocytes from apoptosis via PI3Kdelta/Akt, Rho-A, NFkappaB and Bcl-2/Bcl(XL). Cellular Immunol 2010;263:31-40.
    • (2010) Cellular Immunol , vol.263 , pp. 31-40
    • Badr, G.1    Saad, H.2    Waly, H.3    Hassan, K.4    Abdel-Tawab, H.5
  • 17
    • 0345599885 scopus 로고    scopus 로고
    • Influence of intraluminal thrombus on structural and cellular composition of abdominal aortic aneurysm wall
    • Kazi M, Thyberg J, Religa P, Roy J, Eriksson P, Hedin U, Swedenborg J: Influence of intraluminal thrombus on structural and cellular composition of abdominal aortic aneurysm wall. J Vasc Surg 2003;38:1283-1292.
    • (2003) J Vasc Surg , vol.38 , pp. 1283-1292
    • Kazi, M.1    Thyberg, J.2    Religa, P.3    Roy, J.4    Eriksson, P.5    Hedin, U.6    Swedenborg, J.7
  • 18
    • 0022479541 scopus 로고
    • Immunohistochemical analyses of estrogen receptor in endometrial adeno-carcinoma using a monoclonal antibody
    • Budwit-Novotny DA, McCarty KS, Cox EB, Soper JT, Mutch DG, Creasman WT: Immunohistochemical analyses of estrogen receptor in endometrial adeno-carcinoma using a monoclonal antibody. Cancer Res 1986;46:5419-5425.
    • (1986) Cancer Res , vol.46 , pp. 5419-5425
    • Budwit-Novotny, D.A.1    McCarty, K.S.2    Cox, E.B.3    Soper, J.T.4    Mutch, D.G.5    Creasman, W.T.6
  • 19
    • 0033181346 scopus 로고    scopus 로고
    • Expression of a6 and b4 integrin subunits throughout the menstrual cycle: No correlation with uterine receptivity
    • Murray MJ, Zhang J, Lessey BA: Expression of a6 and b4 integrin subunits throughout the menstrual cycle: no correlation with uterine receptivity. Fertil Steri 1999;72:522-526.
    • (1999) Fertil Steri , vol.72 , pp. 522-526
    • Murray, M.J.1    Zhang, J.2    Lessey, B.A.3
  • 20
    • 3743088829 scopus 로고
    • Ultrastructural study on Semithin section
    • Gupta PD: Ultrastructural study on Semithin section. Science Tools 1983;30:6-7.
    • (1983) Science Tools , vol.30 , pp. 6-7
    • Gupta, P.D.1
  • 22
    • 34547116656 scopus 로고    scopus 로고
    • Type Interferon Receptors: Biochemistry and Biological Functions
    • Nicole A, de Weerd SA, Samarajiwa, Paul JH: Type Interferon Receptors: Biochemistry and Biological Functions. J Biol Chem 2007;28:20053-20057.
    • (2007) J Biol Chem , vol.28 , pp. 20053-20057
    • Nicole, A.1    De Weerd, S.A.2    Samarajiwa Paul, J.H.3
  • 23
    • 35148815311 scopus 로고    scopus 로고
    • Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2
    • Marijanovic Z, Ragimbeau J, Van Heyden J, Uzé G, Pellegrini S: Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2. Biochem J 2007;407:141-151.
    • (2007) Biochem J , vol.407 , pp. 141-151
    • Marijanovic, Z.1    Ragimbeau, J.2    Van Heyden, J.3    Uzé, G.4    Pellegrini, S.5
  • 24
    • 33750364634 scopus 로고    scopus 로고
    • Blocking monoclonal antibodies specific for mouse IFN-alpha/beta receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection
    • Sheehan KC, Lai KS, Dunn GP: Blocking monoclonal antibodies specific for mouse IFN-alpha/beta receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection. J Inter-feron Cytokine Res 2006;26:804-819.
    • (2006) J Interferon Cytokine Res , vol.26 , pp. 804-819
    • Sheehan, K.C.1    Lai, K.S.2    Dunn, G.P.3
  • 25
    • 0038549067 scopus 로고    scopus 로고
    • PI3K in lymphocyte development, differentiation and activation
    • Okkenhaug K, Vanhaesebroeck B: PI3K in lymphocyte development, differentiation and activation. Nat Rev Immuno 2003;3:317-330.
    • (2003) Nat Rev Immuno , vol.3 , pp. 317-330
    • Okkenhaug, K.1    Vanhaesebroeck, B.2
  • 27
    • 0035900481 scopus 로고    scopus 로고
    • Induction of dendritic cell differentiation by IFN-α in systemic lupuerythematosus
    • Blanco P, Palucka AK, Gill M, Pascual V, Banchereau J: Induction of dendritic cell differentiation by IFN-α in systemic lupuerythematosus. Science 2001;294:1540-1543.
    • (2001) Science , vol.294 , pp. 1540-1543
    • Blanco, P.1    Palucka, A.K.2    Gill, M.3    Pascual, V.4    Banchereau, J.5
  • 28
    • 0032695108 scopus 로고    scopus 로고
    • Natural adjuvants: Endogenous activators of dendritic cells
    • Gallucci S, Lolkema M, Matzinger P: Natural adjuvants: endogenous activators of dendritic cells. Nat Med 1999;5:1249-1255.
    • (1999) Nat Med , vol.5 , pp. 1249-1255
    • Gallucci, S.1    Lolkema, M.2    Matzinger, P.3
  • 29
    • 0035284744 scopus 로고    scopus 로고
    • Differential regulation of human blood dendritic cell subsets by IFNs
    • Ito T, Amakawa R, Inaba M, Ikehara S, Inaba K, Fukuhar S: Differential regulation of human blood dendritic cell subsets by IFNs. J Immunol 2001;166:2961-2969.
    • (2001) J Immunol , vol.166 , pp. 2961-2969
    • Ito, T.1    Amakawa, R.2    Inaba, M.3    Ikehara, S.4    Inaba, K.5    Fukuhar, S.6
  • 30
    • 0030036342 scopus 로고    scopus 로고
    • Induction of bystander T cell proliferation by viruses and type I interferon in vivo
    • Tough DF, Borrow P, Sprent J: Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science 1996;272:1947-1950. (Pubitemid 26234507)
    • (1996) Science , vol.272 , Issue.5270 , pp. 1947-1950
    • Tough, D.F.1    Borrow, P.2    Sprent, J.3
  • 31
    • 24344478196 scopus 로고    scopus 로고
    • Type i interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
    • Kolumam GA, Thomas S, Thompson LJ, Sprent J, Murali-Krishna K: Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection. J Exp Med 2005;202:637-650.
    • (2005) J Exp Med , vol.202 , pp. 637-650
    • Kolumam, G.A.1    Thomas, S.2    Thompson, L.J.3    Sprent, J.4    Murali-Krishna, K.5
  • 33
    • 0033081259 scopus 로고    scopus 로고
    • Type i interferons keep activated T cells alive
    • Marrack P, Kappler J, Mitchell T: Type I interferons keep activated T cells alive. J Exp Med 1999;189:521-530.
    • (1999) J Exp Med , vol.189 , pp. 521-530
    • Marrack, P.1    Kappler, J.2    Mitchell, T.3
  • 34
    • 33644837684 scopus 로고    scopus 로고
    • Cutting edge: The direct action of type i IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection
    • Havenar-Daughton C, Kolumam GA, Murali-Krishna K: Cutting edge: the direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection. J Immunol 2006;176:3315-3319.
    • (2006) J Immunol , vol.176 , pp. 3315-3319
    • Havenar-Daughton, C.1    Kolumam, G.A.2    Murali-Krishna, K.3
  • 35
    • 0028290352 scopus 로고
    • Molecular control of B lymphocyte growth and differentiation
    • Banchereau J, Brière F, Liu YJ, Rousset F: Molecular control of B lymphocyte growth and differentiation. Stem Cells 1994;12:278-288.
    • (1994) Stem Cells , vol.12 , pp. 278-288
    • Banchereau, J.1    Brière, F.2    Liu, Y.J.3    Rousset, F.4
  • 36
    • 0029925555 scopus 로고    scopus 로고
    • Changes in lymphocyte subsets, interleukin 2, and soluble interleukin 2 receptor in old and very old age
    • Rea IM, Stewart M, Campbell P, Alexander HD, Crockard AD, Morris TC: Changes in lymphocyte subsets, interleukin 2, and soluble interleukin 2 receptor in old and very old age. Gerontology 1996;42:69-78.
    • (1996) Gerontology , vol.42 , pp. 69-78
    • Rea, I.M.1    Stewart, M.2    Campbell, P.3    Alexander, H.D.4    Crockard, A.D.5    Morris, T.C.6
  • 37
    • 17644399064 scopus 로고    scopus 로고
    • IFN-alpha enhances human B-cell chemotaxis by modulating ligand-induced chemokine receptor signaling and inter-nalization
    • Badr G, Borhis G, Treton D, Richard Y: IFN-alpha enhances human B-cell chemotaxis by modulating ligand-induced chemokine receptor signaling and inter-nalization. Int Immunol 2005;17:459-467.
    • (2005) Int Immunol , vol.17 , pp. 459-467
    • Badr, G.1    Borhis, G.2    Treton, D.3    Richard, Y.4
  • 38
    • 0028784288 scopus 로고
    • Resident bone marrow macrophages produce type 1 interferons that can selectively inhibit interleukin-7-driven growth of B lineage cells
    • Wang J, Lin Q, Langston H, Cooper MD: Resident bone marrow macrophages produce type 1 interferons that can selectively inhibit interleukin-7-driven growth of B lineage cells. Immunit 1995;3:475-484.
    • (1995) Immunit , vol.3 , pp. 475-484
    • Wang, J.1    Lin, Q.2    Langston, H.3    Cooper, M.D.4
  • 39
    • 0031962665 scopus 로고    scopus 로고
    • Impairment of T and B cell development by treatment with a type i interferon
    • Lin Q, Dong C, Cooper MD: Impairment of T and B cell development by treatment with a type I interferon. J Exp Med 1998;187:79-87.
    • (1998) J Exp Med , vol.187 , pp. 79-87
    • Lin, Q.1    Dong, C.2    Cooper, M.D.3
  • 40
    • 4043082729 scopus 로고    scopus 로고
    • Cutting edge: Differential roles for phosphoinositide 3-kinases, p110gamma and p110delta, in lymphocyte chemo-taxis and homing
    • Reif K, Okkenhaug K, Sasaki T, Penninger JM, Vanhaesebroeck B, Cyster JG: Cutting edge: differential roles for phosphoinositide 3-kinases, p110gamma and p110delta, in lymphocyte chemo-taxis and homing. J Immunol 2004;173:2236-2240.
    • (2004) J Immunol , vol.173 , pp. 2236-2240
    • Reif, K.1    Okkenhaug, K.2    Sasaki, T.3    Penninger, J.M.4    Vanhaesebroeck, B.5    Cyster, J.G.6
  • 41
    • 0029153736 scopus 로고
    • High endothelial venules (HEVs): Specialized endothelium for lymphocyte migration
    • Girard JP, Springer TA: High endothelial venules (HEVs): specialized endothelium for lymphocyte migration. Immunol 1995;16:449-457.
    • (1995) Immunol , vol.16 , pp. 449-457
    • Girard, J.P.1    Springer, T.A.2
  • 42
    • 0033214348 scopus 로고    scopus 로고
    • CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lym-phoid organs
    • Forster R, Schubel A, Breitfeld D: CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lym-phoid organs. Cell 1999;99:23-33.
    • (1999) Cell , vol.99 , pp. 23-33
    • Forster, R.1    Schubel, A.2    Breitfeld, D.3
  • 43
    • 34447270217 scopus 로고    scopus 로고
    • Tezosentan attenuates organ injury and mesenteric blood flow decrease in endotoxemia and cecal ligation and puncture
    • Erdem A, Sevgili AM, Akbiyik F: Tezosentan attenuates organ injury and mesenteric blood flow decrease in endotoxemia and cecal ligation and puncture. J Surg Res 2007;141:211-219.
    • (2007) J Surg Res , vol.141 , pp. 211-219
    • Erdem, A.1    Sevgili, A.M.2    Akbiyik, F.3
  • 44
    • 0033945846 scopus 로고    scopus 로고
    • Mitochon-drial oxidative stress plays a key role in aging and apoptosis
    • Sastre J, Pallardo F V, Vina J: Mitochon-drial oxidative stress plays a key role in aging and apoptosis. Life 2000;49:427-435.
    • (2000) Life , vol.49 , pp. 427-435
    • Sastre, J.1    Pallardo, F.V.2    Vina, J.3
  • 47
    • 0942287736 scopus 로고    scopus 로고
    • Ul-trastructural study shows morphologic features of apoptosis and para-apoptosis in megakaryocytes from patients with idiopathic thrombocytopenic purpura
    • Houwerzijl EJ, Blom NR, Want JJd, Esselink MT, Koornstra JJ, Smit JW, Louwes H, Vellenga E, de Wolf JT: Ul-trastructural study shows morphologic features of apoptosis and para-apoptosis in megakaryocytes from patients with idiopathic thrombocytopenic purpura. Blood 2004;103:500-506.
    • (2004) Blood , vol.103 , pp. 500-506
    • Houwerzijl, E.J.1    Blom, N.R.2    Jjd, W.3    Esselink, M.T.4    Koornstra, J.J.5    Smit, J.W.6    Louwes, H.7    Vellenga, E.8    De Wolf, J.T.9
  • 48
    • 0029064840 scopus 로고
    • Evaluation of cell death in EBV-transformed lymphocytes using agarose gel electro-phoresis, light microscopy and electron microscopy. II. Induction of non-classic apoptosis ("para-apoptosis") by tritiated thymidine
    • Asher E, Payne CM, Bernstein C: Evaluation of cell death in EBV-transformed lymphocytes using agarose gel electro-phoresis, light microscopy and electron microscopy. II. Induction of non-classic apoptosis ("para-apoptosis") by tritiated thymidine. Leuk Lymphoma 1995;19:107-119.
    • (1995) Leuk Lymphoma , vol.19 , pp. 107-119
    • Asher, E.1    Payne, C.M.2    Bernstein, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.