Synthesis and biological evaluation of novel dihydro-aryl/alkylsulfanyl- cyclohexylmethyl-oxopyrimidines (S-DACOs) as high active anti-HIV agents

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 2, 2011, Pages 694-697

  He, Yan Ping ^a   Long, Jin ^b   Zhang, Shui Shuan ^a   Li, Cong ^a   Lai, Christopher Cong ^c   Zhang, Chun Sheng ^a   Li, Da Xiong ^a   Zhang, De Hua ^a   Wang, Hua ^a   Cai, Qing Qing ^a   Zheng, Yong Tang ^b  

^a YUNNAN UNIVERSITY   (China)

^b KUNMING INSTITUTE OF ZOOLOGY   (China)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Anti HIV 1 activity; NNRTIs; S DABOs; S DACOs

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; NEVIRAPINE; PYRIMIDINE DERIVATIVE; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ANTI-HIV AGENTS; CELL LINE; HIV INFECTIONS; HIV-1; HUMANS; LEUKOCYTES, MONONUCLEAR; NEVIRAPINE; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; ZIDOVUDINE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 78651248497     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.12.003     Document Type: Article

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