1-(Arylsulfonyl)-2,3-dihydro-1H-quinolin-4-one derivatives as 5-HT 6 serotonin receptor ligands

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 2, 2011, Pages 698-703

  Park, Chul Min ^a   Choi, Jin Il ^a   Choi, Jung Hwan ^a   Kim, So Young ^a   Park, Woo Kyu ^a   Seong, Churl Min ^a  

^a Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

5 HT 6 receptor; Antagonist; Brain penetrant; Memory dysfunction

Indexed keywords

1 (ARYLSULFONYL) 2,3 DIHYDRO 1H QUINOLIN 4 ONE DERIVATIVE; SEROTONIN 6 ANTAGONIST; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG BINDING; DRUG SYNTHESIS; IC 50; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL LINE; HUMANS; LIGANDS; MODELS, MOLECULAR; PROTEIN BINDING; QUINOLONES; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78651229959     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.12.007     Document Type: Article

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