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Volumn 3, Issue 12, 2010, Pages 3614-3628

Pharmacogenetics of SSRIs and sexual dysfunction

Author keywords

Depressio; Drug metabolism; Glutamate; Polymorphism; Serotonin; Sexual dysfunction; SSRI

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CITALOPRAM; CYTOCHROME P450 2D6; FLUOXETINE; GLUTAMIC ACID; PAROXETINE; SERINE PROTEINASE OMI; SEROTONIN; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; SERTRALINE;

EID: 78651229223     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph3123614     Document Type: Review
Times cited : (16)

References (45)
  • 1
    • 0037831023 scopus 로고    scopus 로고
    • The epidemiology of major depressive disorder: Results from the National Comorbidity Survey Replication (NCS-R)
    • Kessler, R.C.; Berglund, P.; Demler, O.; Jin, R.; Koretz, D.; Merikangas, K.R.; Rush, A.J.; Walters, E.E.; Wang, P.S. The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA 2003, 289, 3095-3105.
    • (2003) JAMA , vol.289 , pp. 3095-3105
    • Kessler, R.C.1    Berglund, P.2    Demler, O.3    Jin, R.4    Koretz, D.5    Merikangas, K.R.6    Rush, A.J.7    Walters, E.E.8    Wang, P.S.9
  • 2
    • 27244440335 scopus 로고    scopus 로고
    • Efficacy and tolerability of tricyclic antidepressants and SSRIs compared with placebo for treatment of depression in primary care: A meta-analysis
    • Arroll, B.; Macgillivray, S.; Ogston, S.; Reid, I.; Sullivan, F.; Williams, B.; Crombie, I. Efficacy and tolerability of tricyclic antidepressants and SSRIs compared with placebo for treatment of depression in primary care: a meta-analysis. Ann. Fam. Med. 2005, 3, 449-456.
    • (2005) Ann. Fam. Med , vol.3 , pp. 449-456
    • Arroll, B.1    Macgillivray, S.2    Ogston, S.3    Reid, I.4    Sullivan, F.5    Williams, B.6    Crombie, I.7
  • 5
    • 0037130645 scopus 로고    scopus 로고
    • Discontinuation of use and switching of antidepressants: Influence of patient-physician communication
    • Bull, S.A.; Hu, X.H.; Hunkeler, E.M.; Lee, J.Y.; Ming, E.E.; Markson, L.E.; Fireman, B. Discontinuation of use and switching of antidepressants: influence of patient-physician communication. JAMA 2002, 288, 1403-1409.
    • (2002) JAMA , vol.288 , pp. 1403-1409
    • Bull, S.A.1    Hu, X.H.2    Hunkeler, E.M.3    Lee, J.Y.4    Ming, E.E.5    Markson, L.E.6    Fireman, B.7
  • 6
    • 0041328396 scopus 로고    scopus 로고
    • Drug information sources and antidepressant adherence
    • Sleath, B.; Wurst, K.; Lowery, T. Drug information sources and antidepressant adherence. Community Ment. Health J. 2003, 39, 359-368.
    • (2003) Community Ment. Health J , vol.39 , pp. 359-368
    • Sleath, B.1    Wurst, K.2    Lowery, T.3
  • 7
    • 67649695972 scopus 로고    scopus 로고
    • The association of serotonin transporter genotypes and selective serotonin reuptake inhibitor (SSRI)-associated sexual side effects: Possible relationship to oral contraceptives
    • Bishop, J.R.; Ellingrod, V.L.; Akroush, M.; Moline, J. The association of serotonin transporter genotypes and selective serotonin reuptake inhibitor (SSRI)-associated sexual side effects: possible relationship to oral contraceptives. Hum. Psychopharmacol. 2009, 24, 207-215.
    • (2009) Hum. Psychopharmacol , vol.24 , pp. 207-215
    • Bishop, J.R.1    Ellingrod, V.L.2    Akroush, M.3    Moline, J.4
  • 9
    • 0035108671 scopus 로고    scopus 로고
    • Incidence of sexual dysfunction associated with antidepressant agents: A prospective multicenter study of 1022 outpatients. Spanish Working Group for the Study of Psychotropic-Related Sexual Dysfunction
    • Montejo, A.L.; Llorca, G.; Izquierdo, J.A.; Rico-Villademoros, F. Incidence of sexual dysfunction associated with antidepressant agents: a prospective multicenter study of 1022 outpatients. Spanish Working Group for the Study of Psychotropic-Related Sexual Dysfunction. J. Clin. Psychiatry 2001, 62 (Suppl. 3), 10-21.
    • (2001) J. Clin. Psychiatry , vol.62 , Issue.SUPPL. 3 , pp. 10-21
    • Montejo, A.L.1    Llorca, G.2    Izquierdo, J.A.3    Rico-Villademoros, F.4
  • 10
    • 0031860412 scopus 로고    scopus 로고
    • Accommodation to serotonin reuptake inhibitor-induced sexual dysfunction
    • Ashton, A.K.; Rosen, R.C. Accommodation to serotonin reuptake inhibitor-induced sexual dysfunction. J. Sex Mar. Ther. 1998, 24, 191-192.
    • (1998) J. Sex Mar. Ther , vol.24 , pp. 191-192
    • Ashton, A.K.1    Rosen, R.C.2
  • 12
    • 0032958811 scopus 로고    scopus 로고
    • Effects of SSRIs on sexual function: A critical review
    • Rosen, R.C.; Lane, R.M.; Menza, M. Effects of SSRIs on sexual function: a critical review. J. Clin. Psychopharmacol. 1999, 19, 67-85.
    • (1999) J. Clin. Psychopharmacol , vol.19 , pp. 67-85
    • Rosen, R.C.1    Lane, R.M.2    Menza, M.3
  • 13
    • 0035057365 scopus 로고    scopus 로고
    • The psychopharmacology of sex, part 2: Effects of drugs and disease on the 3 phases of human sexual response
    • Stahl, S.M. The psychopharmacology of sex, part 2: effects of drugs and disease on the 3 phases of human sexual response. J. Clin. Psychiatry 2001, 62, 147-148.
    • (2001) J. Clin. Psychiatry , vol.62 , pp. 147-148
    • Stahl, S.M.1
  • 14
    • 67349153032 scopus 로고    scopus 로고
    • Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients
    • Perlis, R.H.; Laje, G.; Smoller, J.W.; Fava, M.; Rush, A.J.; McMahon, F.J. Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients. Neuropsychopharmacology 2009, 34, 1819-1828.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1819-1828
    • Perlis, R.H.1    Laje, G.2    Smoller, J.W.3    Fava, M.4    Rush, A.J.5    McMahon, F.J.6
  • 15
    • 0031917424 scopus 로고    scopus 로고
    • Basic psychopharmacology of antidepressants, part 1: Antidepressants have seven distinct mechanisms of action
    • Stahl, S.M. Basic psychopharmacology of antidepressants, part 1: Antidepressants have seven distinct mechanisms of action. J. Clin. Psychiatry 1998, 59 (Suppl. 4), 5-14.
    • (1998) J. Clin. Psychiatry , vol.59 , Issue.SUPPL. 4 , pp. 5-14
    • Stahl, S.M.1
  • 16
    • 0024473086 scopus 로고
    • The role of the 5-HT2 receptor in the regulation of sexual performance of male rats
    • Foreman, M.M.; Hall, J.L.; Love, R.L. The role of the 5-HT2 receptor in the regulation of sexual performance of male rats. Life Sci. 1989, 45, 1263-1270.
    • (1989) Life Sci , vol.45 , pp. 1263-1270
    • Foreman, M.M.1    Hall, J.L.2    Love, R.L.3
  • 17
    • 0024538865 scopus 로고
    • Effects of psychotropic drugs on human erection and ejaculation
    • Segraves, R.T. Effects of psychotropic drugs on human erection and ejaculation. Arch. Gen. Psychiatry 1989, 46, 275-284.
    • (1989) Arch. Gen. Psychiatry , vol.46 , pp. 275-284
    • Segraves, R.T.1
  • 18
    • 0036660720 scopus 로고    scopus 로고
    • Mechanisms and treatments of SSRI-induced sexual dysfunction
    • Keltner, N.L.; McAfee, K.M.; Taylor, C.L. Mechanisms and treatments of SSRI-induced sexual dysfunction. Perspect. Psychiatr. Care 2002, 38, 111-116.
    • (2002) Perspect. Psychiatr. Care , vol.38 , pp. 111-116
    • Keltner, N.L.1    McAfee, K.M.2    Taylor, C.L.3
  • 19
    • 78651226017 scopus 로고    scopus 로고
    • GlaxoSmithKline, Paxil Prescribing Information
    • GlaxoSmithKline, Paxil Prescribing Information. 2008.
    • (2008)
  • 20
    • 0036124107 scopus 로고    scopus 로고
    • CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
    • Bradford
    • Bradford, L.D. CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics 2002, 3, 229-243.
    • (2002) Pharmacogenomics , vol.3 , pp. 229-243
    • Bradford, L.D.1
  • 21
    • 0036789442 scopus 로고    scopus 로고
    • Relationship between CYP 2D6 metabolic status and sexual dysfunction in paroxetine treatment
    • Zourkova, A.; Hadasova, E. Relationship between CYP 2D6 metabolic status and sexual dysfunction in paroxetine treatment. J. Sex Mar. Ther. 2002, 28, 451-461.
    • (2002) J. Sex Mar. Ther , vol.28 , pp. 451-461
    • Zourkova, A.1    Hadasova, E.2
  • 22
    • 34249889916 scopus 로고    scopus 로고
    • Links among paroxetine-induced sexual dysfunctions, gender, and CYP2D6 activity
    • Zourkova, A.; Ceskova, E.; Hadasova, E.; Ravcukova, B. Links among paroxetine-induced sexual dysfunctions, gender, and CYP2D6 activity. J. Sex Mar. Ther. 2007, 33, 343-355.
    • (2007) J. Sex Mar. Ther , vol.33 , pp. 343-355
    • Zourkova, A.1    Ceskova, E.2    Hadasova, E.3    Ravcukova, B.4
  • 23
    • 33748766341 scopus 로고    scopus 로고
    • Serotonin 2A -1438 G/A and G-protein Beta3 subunit C825T polymorphisms in patients with depression and SSRI- associated sexual side-effects
    • Bishop, J.R.; Moline, J.; Ellingrod, V.L.; Schultz, S.K.; Clayton, A.H. Serotonin 2A -1438 G/A and G-protein Beta3 subunit C825T polymorphisms in patients with depression and SSRI- associated sexual side-effects. Neuropsychopharmacology 2006, 31, 2281-2288.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2281-2288
    • Bishop, J.R.1    Moline, J.2    Ellingrod, V.L.3    Schultz, S.K.4    Clayton, A.H.5
  • 24
    • 4444232862 scopus 로고    scopus 로고
    • The-1438A/G polymorphism in the 5-hydroxytryptamine type 2A receptor gene affects promoter activity
    • Parsons, M.J.; D'Souza, U.M.; Arranz, M.J.; Kerwin, R.W.; Makoff, A.J. The -1438A/G polymorphism in the 5-hydroxytryptamine type 2A receptor gene affects promoter activity. Biol. Psychiatry 2004, 56, 406-410.
    • (2004) Biol. Psychiatry , vol.56 , pp. 406-410
    • Parsons, M.J.1    D'souza, U.M.2    Arranz, M.J.3    Kerwin, R.W.4    Makoff, A.J.5
  • 25
    • 0033852571 scopus 로고    scopus 로고
    • G protein beta 3 gene: Structure, promoter, and additional polymorphisms
    • Rosskopf, D.; Busch, S.; Manthey, I.; Siffert, W. G protein beta 3 gene: structure, promoter, and additional polymorphisms. Hypertension 2000, 36, 33-41.
    • (2000) Hypertension , vol.36 , pp. 33-41
    • Rosskopf, D.1    Busch, S.2    Manthey, I.3    Siffert, W.4
  • 27
    • 0031422451 scopus 로고    scopus 로고
    • The Changes in Sexual Functioning Questionnaire (CSFQ): Development, reliability, and validity
    • Clayton, A.H.; McGarvey, E.L.; Clavet, G.J. The Changes in Sexual Functioning Questionnaire (CSFQ): development, reliability, and validity. Psychopharmacol. Bull. 1997, 33, 731-745.
    • (1997) Psychopharmacol. Bull , vol.33 , pp. 731-745
    • Clayton, A.H.1    McGarvey, E.L.2    Clavet, G.J.3
  • 29
  • 36
    • 70249083016 scopus 로고    scopus 로고
    • Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients
    • Laje, G.; Allen, A.S.; Akula, N.; Manji, H.; John Rush, A.; McMahon, F.J. Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients. Pharmacogenet. Genomics 2009, 19, 666-674.
    • (2009) Pharmacogenet. Genomics , vol.19 , pp. 666-674
    • Laje, G.1    Allen, A.S.2    Akula, N.3    Manji, H.4    John, R.A.5    McMahon, F.J.6
  • 37
    • 58149523185 scopus 로고    scopus 로고
    • Serotonin transporter promoter region (5-HTTLPR) polymorphism is associated with the intravaginal ejaculation latency time in Dutch men with lifelong premature ejaculation
    • Janssen, P.K.; Bakker, S.C.; Rethelyi, J.; Zwinderman, A.H.; Touw, D.J.; Olivier, B.; Waldinger, M.D. Serotonin transporter promoter region (5-HTTLPR) polymorphism is associated with the intravaginal ejaculation latency time in Dutch men with lifelong premature ejaculation. J. Sex Med. 2009, 6, 276-284.
    • (2009) J. Sex Med , vol.6 , pp. 276-284
    • Janssen, P.K.1    Bakker, S.C.2    Rethelyi, J.3    Zwinderman, A.H.4    Touw, D.J.5    Olivier, B.6    Waldinger, M.D.7
  • 38
    • 72149084933 scopus 로고    scopus 로고
    • Analysis of association between the 5-HTTLPR and STin2 polymorphisms in the serotonin-transporter gene and clinical response to a selective serotonin reuptake inhibitor (sertraline) in patients with premature ejaculation
    • Safarinejad, M.R. Analysis of association between the 5-HTTLPR and STin2 polymorphisms in the serotonin-transporter gene and clinical response to a selective serotonin reuptake inhibitor (sertraline) in patients with premature ejaculation. BJU Int. 2009, 105, 73-78.
    • (2009) BJU Int , vol.105 , pp. 73-78
    • Safarinejad, M.R.1
  • 39
    • 0032841176 scopus 로고    scopus 로고
    • An intronic polymorphic domain often associated with susceptibility to affective disorders has allele dependent differential enhancer activity in embryonic stem cells
    • Fiskerstrand, C.E.; Lovejoy, E.A.; Quinn, J.P. An intronic polymorphic domain often associated with susceptibility to affective disorders has allele dependent differential enhancer activity in embryonic stem cells. FEBS Lett. 1999, 458, 171-174.
    • (1999) FEBS Lett , vol.458 , pp. 171-174
    • Fiskerstrand, C.E.1    Lovejoy, E.A.2    Quinn, J.P.3
  • 40
    • 33847257284 scopus 로고    scopus 로고
    • Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with selective serotonin reuptake inhibitor efficacy in depressed patients
    • Serretti
    • Serretti, A.; Kato, M.; De Ronchi, D.; Kinoshita, T. Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with selective serotonin reuptake inhibitor efficacy in depressed patients. Mol. Psychiatry 2007, 12, 247-257.
    • (2007) Mol. Psychiatry , vol.12 , pp. 247-257
    • Serretti, A.1    Kato, M.2    de Ronchi, D.3    Kinoshita, T.4
  • 41
    • 7744233997 scopus 로고    scopus 로고
    • Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depression
    • Murphy, G.M., Jr.; Hollander, S.B.; Rodrigues, H.E.; Kremer, C.; Schatzberg, A.F. Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depression. Arch. Gen. Psychiat. 2004, 61, 1163-1169.
    • (2004) Arch. Gen. Psychiat , vol.61 , pp. 1163-1169
    • Murphy Jr., G.M.1    Hollander, S.B.2    Rodrigues, H.E.3    Kremer, C.4    Schatzberg, A.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.