A hidden incoherent switch regulates RCAN1 in the calcineurin-NFAT signaling network

Journal of Cell Science

Volumn 124, Issue 1, 2011, Pages 82-90

  Shin, Sung Young ^a   Yang, Hee Won ^a   Kim, Jeong Rae ^a,b   Heo, Won Do ^a   Cho, Kwang Hyun ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b University of Seoul   (South Korea)

Author keywords

Calcineurin NFAT signaling pathway; Cardiac hypertrophy; Incoherent regulation switch; Mathematical modeling; RCAN1; Systems biology

Indexed keywords

CALCINEURIN; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN REGULATOR OF CALCINEURIN 1; REGULATOR PROTEIN; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ARTICLE; HUMAN; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; CALCINEURIN; CELL LINE, TUMOR; GENE EXPRESSION REGULATION; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MUSCLE PROTEINS; NFATC TRANSCRIPTION FACTORS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

EID: 78651092705     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.076034     Document Type: Article

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