Nuclease deficiencies promote end-stage lupus nephritis but not nephritogenic autoimmunity in (NZB × NZW) F1 mice

Immunology and Cell Biology

Volumn 89, Issue 1, 2011, Pages 90-99

  Fismen, Silje ^a   Mortensen, Elin S ^a,b   Rekvig, Ole P ^a,b  

^a UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

^b UNIVERSITY OF TROMSØ   (Norway)

Author keywords

autoimmunity; chromatin fragments; lupus nephritis; nucleases; nucleosomes; systemic lupus erythematosus

Indexed keywords

ANTIBODY; AUTOANTIBODY; CHROMATIN ANTIBODY; DEOXYRIBONUCLEASE I; DOUBLE STRANDED DNA ANTIBODY; IMMUNOGLOBULIN G; NUCLEASE; NUCLEOSOME ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIBODY PRODUCTION; APOPTOSIS; AUTOIMMUNITY; CHROMATIN; DISEASE COURSE; ENZYME ACTIVITY; ENZYME DEFICIENCY; GLOMERULUS BASEMENT MEMBRANE; HUMAN; HUMAN TISSUE; IMMUNE COMPLEX DEPOSITION; LUPUS ERYTHEMATOSUS NEPHRITIS; MOUSE; NONHUMAN; REVIEW;

ANIMALS; ANTIBODIES, ANTINUCLEAR; ANTIGEN-ANTIBODY COMPLEX; AUTOIMMUNITY; CHROMATIN; DOWN-REGULATION; ENDODEOXYRIBONUCLEASES; HUMANS; KIDNEY FAILURE, CHRONIC; LUPUS NEPHRITIS; MICE; MICE, INBRED NZB;

MUS;

EID: 78651077521     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2010.75     Document Type: Review

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