Acidosis of rat dorsal vagal neurons in situ during spontaneous and evoked activity

Journal of Physiology

Volumn 496, Issue 3, 1996, Pages 695-710

  Trapp, S ^a,c   Luckermann M ^a   Brooks, P A ^a,b   Ballanyi, K ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; BICARBONATE; BICUCULLINE; BUFFER; CADMIUM; KAINIC ACID; NICKEL; TETRODOTOXIN;

ACIDOSIS; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; BRAIN STEM; CELL MEMBRANE DEPOLARIZATION; CELL PH; CONTROLLED STUDY; FEMALE; MALE; MEMBRANE CURRENT; NERVE CELL; NERVE CELL MEMBRANE POTENTIAL; NERVE CONDUCTION; NONHUMAN; PRIORITY JOURNAL; VAGUS NERVE DORSAL NUCLEUS;

EID: 0029858552     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.1996.sp021720     Document Type: Article

References (39)

1. AHMED, Z. & CONNOR, J. A. (1980). Intracellular pH changes induced by calcium influx during electrical activity in molluscan neurons. Journal of General Physiology 75, 403-426.
2. AMATO, A., BALLERINI, L. & ATTWELL, D. (1994). Intracellular pH changes produced by glutamate uptake in rat hippocampal slices. Journal of Neurophysioloyy 72, 1686-1696.
3. BALLANYI, K., DOUTHEIL, J. & BROCKHAUS, J. (1996). Membrane potentials and microenvironment of rat dorsal vagal cell in vitro during energy depletion. Journal of Physiology 495, 769-784.
4. BALLANYI, K., MÜCKENHOFF, K., BELLINGHAM, M. C., OKADA, Y., SCHEID, P. & RICHTER, D. W. (1994). Activity-related pH changes in respiratory neurones and glial cells of cats. NeuroReport 6, 33-36.
5. BORMANN, J., HAMILL, O. P. & SAKMANN, B. (1987). Mechanism of anion permeation through channels gated by glycine and gamma-aminobutyric acid in mouse cultured spinal neurones. Journal of Physiology 385, 243-286.
6. BOUVIER, M., SZATKOWSKI, M., AMATO, A. & ATTWELL, D. (1992). The glial cell glutamate uptake carrier countertransports pH-changing anions. Nature 360, 471-474.
7. BROOKS, P. A., TRAPP, S. & BALLANYI, K. (1995). Relation between excitability and intracellular pH in dorsal vagal neurons of rats in vitro. Pflügers Archiv 429, R26.
8. BROWN, H. M. & MEECH, R. W. (1979). Light induced changes of internal pH in a barnacle photoreceptor and the effect of internal pH on the receptor potential. Journal of Physiology 297, 73-93.
9. BUCKLER, K. J., VAUGHAN-JONES, R. D., PEERS, C. & NYE, P. C. (1991). Intracellular pH and its regulation in isolated type 1 carotid body cells of the neonatal rat. Journal of Physiology 436, 107-129.
10. CHESLER, M. (1990). The regulation and modulation of pH in the nervous system. Progress in Neurobioloyy 34, 401-427.
11. CHESLER, M. & KAILA, K. (1992). Modulation of pH by neuronal activity. Trends in Neurosciences 15, 396-402.
12. DECOURSEY, T. E. & CHERNY, V. V. (1994). Voltage-activated hydrogen ion currents. Journal of Membrane Biology 141, 203-223.
13. DIXON, D. B., TAKAHASHI, K.-I. & COPENHAGEN, D. R. (1993). L-Glutamate suppresses HVA calcium current in catfish horizontal cells by raising intracellular proton concentration. Neuron 11, 267-277.
14. EILERS J., SCHNEGGENBURGER, R. & KONNERTH, A. (1990). Patch clamp and calcium imaging in brain slices. In Single Channel Recording, ed. SAKMANN, B. & NEHER, E., pp. 213-229. Plenum Press, New York.
15. ENDRES, W., BALLANYI, K., SERVE, G. & GRAFE, P. (1986). Excitatory amino acids and intracellular pH in motoneurons of the isolated frog spinal cord. Neuroscience Letters 72, 54-58.
16. GAILLARD, S. & DUPONT, J. L. (1990). Ionic control of intracellular pH in rat cerebellar Purkinje cells maintained in culture. Journal of Physiology 425, 71-83.
17. HANSEN, A. J. (1985). Effect of anoxia on ion distribution in the brain. Physiological Reviews 65, 101-148.
18. HEATON, R. C., WRAY, S. & EISNER, D. A. (1993). Effects of metabolic inhibition and changes of intracellular pH on potassium permeability and contraction of rat uterus. Journal of Physiology 465, 43-56.
19. KAILA, K. & VOIPIO, J. (1987). Postsynaptic fall in intracellular pH induced by GABA-activated bicarbonate conductance. Nature 330, 163-165.
20. LÜCKERMANN, M., TRAPP, S., BROOKS, P. A. & BALLANYI, K. (1995). Simultaneous measurements of intracellular pH and membrane currents of rat brainstem neurons in vitro. Proceedings of the 23rd Göttingen Neurobiology Conference II, 632.
21. PAALASMAA, P., TAIRA, T., VOIPIO, J. & KAILA, K. (1994). Extracellular alkaline transients mediated by glutamate receptors in the rat hippocampal slice are not due to a proton conductance. Journal of Neurophysiology 72, 2031-2033.
22. PASTERNACK, M., VOIPIO, J. & KAILA, K. (1993). Intracellular carbonic anhydrase activity and its role in GABA-induced acidosis in isolated rat hippocampal pyramidal neurones. Acta Physiologica Scandinavica 148, 229-231.
23. POCOCK, G. & RICHARDS, C. D. (1992). Hydrogen ion regulation in rat cerebellar granule cells studied by single-cell fluorescence microscopy. European Journal of Neuroscience 4, 136-143.
24. ROOS, A. & BORON, W. F. (1981). Intracellular pH. Physiological Reviews 61, 296-434.
25. SCHWIENING, C. J., KENNEDY, H. J. & THOMAS, R. C. (1993). Calcium-hydrogen exchange by the plasma membrane Ca-ATPase of voltage-clamped snail neurons. Proceedings of the Royal Society B 253, 285-289.
26. SHARP, A. P. & THOMAS, R. C. (1981). The effects of chloride substitution on intracellular pH in crab muscle. Journal of Physiology 312, 71-80.
27. 2+] in hypoxia and ischemia in rat brain in vivo. Journal of General Physiology 95, 837-866.
28. + buffering power of snail neurons. Journal of Physiology 409, 89-101.
29. TERZIC, A., TUNG, R. T. & KURACHI, Y. (1994). Nucleotide regulation of ATP sensitive potassium channels. Cardiovascular Research 28, 746-753.
30. THOMAS, J. A., BUCHSBAUM, R. N., ZIMNIAK, A. & RACKER, E. (1979). Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ. Biochemistry 18, 2210-2218.
31. THOMAS, R. C. (1984). Experimental displacement of intracellular pH and the mechanism of its subsequent recovery. Journal of Physiology 354, 3-22.
32. THOMAS, R. C. (1989). Proton channels in snail neurones: does calcium entry mimic the effects of proton influx? Annals of the New York Academy of Sciences 574, 287-293.
33. ATP channels mediate anoxic outward current in rat dorsal vagal neurons in vitro. Journal of Physiology 487, 37-50.
34. + pump. NeuroReport 7, 2000-2004.
35. TRAVAGLI, R. A., GILLIS, R. A., ROSSITER, C. D. & VICINI, S. (1991). Glutamate and GABA-mediated synaptic currents in neurons of the rat dorsal motor nucleus of the vagus. American Journal of Physiology 260, G531-530.
36. +-sensitive microelectrode based on a PVC-gelled membrane. Pflügers Archiv 423, 193-201.
37. WÄCHTLER, J., MAYER, C., RUCKER, F. & GRAFE, P. (1996). Glucose availability alters ischaemia-induced changes in intracellular pH and calcium of isolated rat spinal roots. Brain Research 725, 30-36.
38. 2+ loads. Journal of Neurophysiology 72, 2563-2569.
39. WERTH, J. L. & THAYER, S. A. (1994). Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons. Journal of Neuroscience 14, 348-356.