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Volumn , Issue 2, 2011, Pages 234-237

A direct, regioselective palladium-catalyzed synthesis of N-substituted benzimidazoles and imidazopyridines

Author keywords

Benzimidazoles; Homogeneous catalysis; Nitrogen heterocycles; Palladium; Regioselectivity

Indexed keywords


EID: 78650884356     PISSN: 1434193X     EISSN: 10990690     Source Type: Journal    
DOI: 10.1002/ejoc.201001423     Document Type: Article
Times cited : (31)

References (34)
  • 12
    • 35048814533 scopus 로고    scopus 로고
    • Angew. Chem. Int. Ed. 2007, 46, 7509-7512.
    • (2007) Angew. Chem. Int. Ed. , vol.46 , pp. 7509-7512
  • 15
    • 34250839461 scopus 로고    scopus 로고
    • Angew. Chem. Int. Ed. 2007, 46, 2598-2601.
    • (2007) Angew. Chem. Int. Ed. , vol.46 , pp. 2598-2601
  • 18
    • 78650881706 scopus 로고    scopus 로고
    • A part of this work has been patented by the authors, see
    • A part of this work has been patented by the authors, see
  • 26
    • 78650876921 scopus 로고    scopus 로고
    • note
    • Control experiments showed no difference in yield of the reaction when racemic BINAP was used instead of (R)-BINAP. The chiral ligand was only used as large amounts were available in our lab.
  • 27
    • 78650901658 scopus 로고    scopus 로고
    • note
    • For mechanistic studies illustrating the role of bidentate phosphine ligands in C-N cross-coupling reactions, see for example
  • 32
    • 78650894947 scopus 로고    scopus 로고
    • note
    • Though variations in the temperature only led to a moderate decrease in yield, a switch from toluene to dioxane completely inhibited product formation.
  • 34
    • 78650863123 scopus 로고    scopus 로고
    • note
    • 2-Methyl-1-phenyl-1H-benzoimidazol-5-carboxylic acid methyl ester was prepared on a 5-g scale from 4-chloro-3-nitrobenzoic acid methyl ester and phenylacetamide.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.