-
1
-
-
0023786047
-
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
-
Vaux DL, Cory S, Adams JM (1988) Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 335: 440-2.
-
(1988)
Nature
, vol.335
, pp. 440-442
-
-
Vaux, D.L.1
Cory, S.2
Adams, J.M.3
-
2
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, et al. (2005) Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 122: 927-39.
-
(2005)
Cell
, vol.122
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
Garuti, R.4
Liang, X.H.5
-
3
-
-
14844315930
-
A novel mechanism of checkpoint abrogation conferred by Chk1 downregulation
-
Xiao Z, Xue J, Sowin TJ, Rosenberg SH, Zhang H (2005) A novel mechanism of checkpoint abrogation conferred by Chk1 downregulation. Oncogene 24: 1403-11.
-
(2005)
Oncogene
, vol.24
, pp. 1403-1411
-
-
Xiao, Z.1
Xue, J.2
Sowin, T.J.3
Rosenberg, S.H.4
Zhang, H.5
-
4
-
-
33751581196
-
-
Chen Z, Xiao Z, Gu WZ, Xue J, Bui MH, et al. (2006) Int J Cancer 119: 2784-94.
-
(2006)
Int J Cancer
, vol.119
, pp. 2784-2794
-
-
Chen, Z.1
Xiao, Z.2
Gu, W.Z.3
Xue, J.4
Bui, M.H.5
-
5
-
-
0041324624
-
Novel direct and indirect cyclin-dependent kinase modulators for the prevention and treatment of human neoplasms
-
Senderowicz AM (2003) Novel direct and indirect cyclin-dependent kinase modulators for the prevention and treatment of human neoplasms. Cancer Chemother Pharmacol 52 Suppl 1: S61-73.
-
(2003)
Cancer Chemother Pharmacol 52 Suppl
, vol.1
-
-
Senderowicz, A.M.1
-
7
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF (2003) Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A 100: 3983-8.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
8
-
-
21344454219
-
Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
-
Ponti D, Costa A, Zaffaroni N, Pratesi G, Petrangolini G, et al. (2005) Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res 65: 5506-11.
-
(2005)
Cancer Res
, vol.65
, pp. 5506-5511
-
-
Ponti, D.1
Costa, A.2
Zaffaroni, N.3
Pratesi, G.4
Petrangolini, G.5
-
9
-
-
35848955428
-
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
-
Ginestier C, Hur MH, Charafe-Jauffret E, Monville F, Dutcher J, et al. (2007) ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1: 555-67.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 555-567
-
-
Ginestier, C.1
Hur, M.H.2
Charafe-Jauffret, E.3
Monville, F.4
Dutcher, J.5
-
10
-
-
33845364233
-
Cancer stem cells and oncology therapeutics
-
Al-Hajj M (2007) Cancer stem cells and oncology therapeutics. Curr Opin Oncol 19: 61-4.
-
(2007)
Curr Opin Oncol
, vol.19
, pp. 61-64
-
-
Al-Hajj, M.1
-
11
-
-
36849078711
-
Let-7 regulates self renewal and tumorigenicity of breast cancer cells
-
Yu F, Yao H, Zhu P, Zhang X, Pan Q, et al. (2007) Let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 131: 1109-1123.
-
(2007)
Cell
, vol.131
, pp. 1109-1123
-
-
Yu, F.1
Yao, H.2
Zhu, P.3
Zhang, X.4
Pan, Q.5
-
12
-
-
33845904383
-
The response of CD24(2/low)/ CD44+ breast cancer-initiating cells to radiation
-
Phillips TM, McBride WH, Pajonk F (2006) The response of CD24(2/low)/ CD44+ breast cancer-initiating cells to radiation. J Natl Cancer Inst 98: 1777-85.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 1777-1785
-
-
Phillips, T.M.1
McBride, W.H.2
Pajonk, F.3
-
13
-
-
33748155240
-
Notch signaling in breast cancer and tumor angiogenesis: Cross-talk and therapeutic potentials
-
Shi W, Harris AL (2006) Notch signaling in breast cancer and tumor angiogenesis: cross-talk and therapeutic potentials. J Mammary Gland Biol Neoplasia 11: 41-52.
-
(2006)
J Mammary Gland Biol Neoplasia
, vol.11
, pp. 41-52
-
-
Shi, W.1
Harris, A.L.2
-
14
-
-
33845874094
-
Cancer stem cells and radiotherapy: New insights into tumor radioresistance
-
Diehn M, Clarke MF (2006) Cancer stem cells and radiotherapy: new insights into tumor radioresistance. J Natl Cancer Inst 98: 1755-7.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 1755-1757
-
-
Diehn, M.1
Clarke, M.F.2
-
15
-
-
0034594628
-
New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
-
Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, et al. (2000) New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92: 205-16.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 205-216
-
-
Therasse, P.1
Arbuck, S.G.2
Eisenhauer, E.A.3
Wanders, J.4
Kaplan, R.S.5
-
16
-
-
44049100934
-
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
-
Li X, Lewis MT, Huang J, Gutierrez C, Osborne CK, et al. (2008) Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst 100: 672-9.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 672-679
-
-
Li, X.1
Lewis, M.T.2
Huang, J.3
Gutierrez, C.4
Osborne, C.K.5
-
17
-
-
68749099671
-
Identification of selective inhibitors of cancer stem cells by high-throughput screening
-
Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, et al. (2009) Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 138: 645-59.
-
(2009)
Cell
, vol.138
, pp. 645-659
-
-
Gupta, P.B.1
Onder, T.T.2
Jiang, G.3
Tao, K.4
Kuperwasser, C.5
-
18
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, et al. (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133: 704-15.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
-
19
-
-
54049096261
-
HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
-
Korkaya H, Paulson A, Iovino F, Wicha MS (2008) HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. Oncogene 27: 6120-30.
-
(2008)
Oncogene
, vol.27
, pp. 6120-6130
-
-
Korkaya, H.1
Paulson, A.2
Iovino, F.3
Wicha, M.S.4
-
20
-
-
0141888537
-
The role of ABC transporters in clinical practice
-
Leonard GD, Fojo T, Bates SE (2003) The role of ABC transporters in clinical practice. Oncologist 8: 411-24.
-
(2003)
Oncologist
, vol.8
, pp. 411-424
-
-
Leonard, G.D.1
Fojo, T.2
Bates, S.E.3
-
21
-
-
23044514578
-
Multiple drug resistance in cancer revisited: The cancer stem cell hypothesis
-
Donnenberg VS, Donnenberg AD (2005) Multiple drug resistance in cancer revisited: the cancer stem cell hypothesis. J Clin Pharmacol 45: 872-7.
-
(2005)
J Clin Pharmacol
, vol.45
, pp. 872-877
-
-
Donnenberg, V.S.1
Donnenberg, A.D.2
-
22
-
-
34247581697
-
Novel cell culture technique for primary ductal carcinoma in situ: Role of Notch and epidermal growth factor receptor signaling pathways
-
Farnie G, Clarke RB, Spence K, Pinnock N, Brennan K, et al. (2007) Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways. J Natl Cancer Inst 99: 616-27.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 616-627
-
-
Farnie, G.1
Clarke, R.B.2
Spence, K.3
Pinnock, N.4
Brennan, K.5
-
23
-
-
38849139125
-
ABCG2 expression and side population abundance regulated by a transforming growth factor beta-directed epithelial-mesenchymal transition
-
Yin L, Castagnino P, Assoian RK (2008) ABCG2 expression and side population abundance regulated by a transforming growth factor beta-directed epithelial-mesenchymal transition. Cancer Res 68: 800-7.
-
(2008)
Cancer Res
, vol.68
, pp. 800-807
-
-
Yin, L.1
Castagnino, P.2
Assoian, R.K.3
-
24
-
-
54249157033
-
Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2
-
Dai CL, Tiwari AK, Wu CP, Su XD, Wang SR, et al. (2008) Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2. Cancer Res 68: 7905-14.
-
(2008)
Cancer Res
, vol.68
, pp. 7905-7914
-
-
Dai, C.L.1
Tiwari, A.K.2
Wu, C.P.3
Su, X.D.4
Wang, S.R.5
-
25
-
-
0347413734
-
Stem cells in normal breast development and breast cancer
-
Dontu G, Al-Hajj M, Abdallah WM, Clarke MF, Wicha MS (2003) Stem cells in normal breast development and breast cancer. Cell Prolif 36 Suppl 1: 59-72.
-
(2003)
Cell Prolif 36 Suppl
, vol.1
, pp. 59-72
-
-
Dontu, G.1
Al-Hajj, M.2
Abdallah, W.M.3
Clarke, M.F.4
Wicha, M.S.5
-
26
-
-
22244433866
-
Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic
-
Patrawala L, Calhoun T, Schneider-Broussard R, Zhou J, Claypool K, et al. (2005) Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic. Cancer Res 65: 6207-19.
-
(2005)
Cancer Res
, vol.65
, pp. 6207-6219
-
-
Patrawala, L.1
Calhoun, T.2
Schneider-Broussard, R.3
Zhou, J.4
Claypool, K.5
-
27
-
-
61349121467
-
Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitiza-tion of chemoresistant cells to undergo apoptosis
-
Nardinocchi L, Puca R, Sacchi A, D'Orazi G (2009) Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitiza-tion of chemoresistant cells to undergo apoptosis. Mol Cancer 8: 1.
-
(2009)
Mol Cancer
, vol.8
, pp. 1
-
-
Nardinocchi, L.1
Puca, R.2
Sacchi, A.3
D'orazi, G.4
-
28
-
-
0034987631
-
Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182,780 (Faslodex)
-
McClelland RA, Barrow D, Madden TA, Dutkowski CM, Pamment J, et al. (2001) Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182,780 (Faslodex). Endocrinology 142: 2776-88.
-
(2001)
Endocrinology
, vol.142
, pp. 2776-2788
-
-
McClelland, R.A.1
Barrow, D.2
Madden, T.A.3
Dutkowski, C.M.4
Pamment, J.5
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