In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS

Journal of Lipid Research

Volumn 52, Issue 1, 2011, Pages 159-169

  Castro Perez, Jose ^a,b   Previs, Stephen F ^a   McLaren, David G ^a   Shah, Vinit ^a   Herath, Kithsiri ^a   Bhat, Gowri ^a   Johns, Douglas G ^a   Wang, Sheng Ping ^a   Mitnaul, Lyndon ^a   Jensen, Kristian ^a   Vreeken, Robert ^b,c   Hankemeier, Thomas ^b,c   Roddy, Thomas P ^a   Hubbard, Brian K ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NETHERLANDS METABOLOMICS CENTRE   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Fl ux; Lipids; Liquid chromatography mass spectrometry

Indexed keywords

ACYL COENZYME A DESATURASE; CHOLESTEROL; CHOLESTEROL ESTER; DEUTERIUM OXIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE DIET; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; IN VIVO STUDY; ISOTOPE LABELING; LIPID ANALYSIS; LIPID DIET; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

ANIMALS; CHOLESTEROL; CHOLESTEROL ESTERS; CHROMATOGRAPHY, LIQUID; DEUTERIUM OXIDE; ISOTOPES; MALE; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; PALMITATES; STEAROYL-COA DESATURASE;

EID: 78650852953     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.D009787     Document Type: Article

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