Cocaine-insensitive dopamine transporters with intact substrate transport produced by self-administration

Biological Psychiatry

Volumn 69, Issue 3, 2011, Pages 201-207

  Ferris, Mark J ^a   Mateo, Yolanda ^a   Roberts, David C S ^a   Jones, Sara R ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Amphetamine; cocaine; dopamine; microdialysis; self administration; voltammetry

Indexed keywords

AMPHETAMINE; COCAINE; DOPAMINE TRANSPORTER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; CYCLIC POTENTIOMETRY; DOPAMINE BRAIN LEVEL; DOPAMINE RELEASE; DOPAMINE UPTAKE; DRUG EFFICACY; DRUG MEGADOSE; DRUG SELF ADMINISTRATION; DRUG SENSITIVITY; IN VIVO STUDY; MALE; MICRODIALYSIS; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT;

AMPHETAMINE; ANIMALS; COCAINE; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; DRUG TOLERANCE; ELECTROCHEMICAL TECHNIQUES; MALE; MICRODIALYSIS; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY; SELF ADMINISTRATION;

EID: 78650849997     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2010.06.026     Document Type: Article

References (42)

1. M.J. Wanat, I. Willuhn, J.J. Clark, and P.E. Phillips Phasic dopamine release in appetitive behaviors and drug addiction Curr Drug Abuse Rev 2 2009 195 213
2. W. Schultz Behavioral dopamine signals Trends Neurosci 30 2007 203 210
3. H.E. Melikian, and K.M. Buckley Membrane trafficking regulates the activity of the human dopamine transporter J Neurosci 19 1999 7699 7710
4. N.R. Zahniser, and A. Sorkin Trafficking of dopamine transporters in psychostimulant actions Semin Cell Dev Biol 20 2009 411 417
5. J. Eriksen, S.G.F. Rasmussen, T.N. Rasmussen, C.B. Vaegter, J.H. Cha, and M.F. Zou Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs J Neurosci 29 2009 6794 6808
6. C.A. Furman, R. Chen, B. Guptaroy, M. Zhang, R.W. Holz, and M. Gnegy Dopamine and amphetamine rapidly increase dopamine transporter trafficking to the surface: Live-cell imaging using total internal reflection fluorescence microscopy J Neurosci 29 2009 3328 3336
7. L.A. Johnson, C.A. Furman, M.J. Zhang, B. Guptaroy, and M.E. Gnegy Rapid delivery of the dopamine transporter to the plasmalemmal membrane upon amphetamine stimulation Neuropharmacology 49 2005 750 758
8. E. Boudanova, D.A. Navaroli, and H.E. Melikian Amphetamine-induced decreases in dopamine transporter surface expression are protein kinase C-independent Neuropharmacology 54 2008 605 612
9. J.D. Foster, S.D. Adkins, J.R. Lever, and R.A. Vaughan Phorbol ester induced trafficking-independent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol J Neurochem 105 2008 1683 1699
10. R. Chen, C.A. Furman, M.J. Zhang, M.N. Kim, R.W. Gereau, M. Leitges, and M.E. Gnegy Protein kinase C beta is a critical regulator of dopamine transporter trafficking and regulates the behavioral response to amphetamine in mice J Pharmacol Exp Ther 328 2009 912 920
11. G.R. Uhl, and Z.C. Lin The top 20 dopamine transporter mutants: Structure-function relationships and cocaine actions Eur J Pharmacol 479 2003 71 82
12. T.J. Volz, and J.O. Schenk A comprehensive atlas of the topography of functional groups of the dopamine transporter Synapse 58 2005 72 94
13. X.H. Wu, and H.H. Gu Cocaine affinity decreased by mutations of aromatic residue phenylalanine 105 in the transmembrane domain 2 of dopamine transporter Mol Pharmacol 63 2003 653 658
14. B. Giros, Y.M. Wang, S. Suter, S.B. McLeskey, C. Pifl, and M.G. Caron Delineation of discrete domains for substrate, cocaine, and tricyclic antidepressant interactions using chimeric dopamine-norepinephrine transporters J Biol Chem 269 1994 15985 15988
15. D.E. Dar, T.G. Metzger, D.J. Vandenbergh, and G.R. Uhl Dopamine uptake and cocaine binding mechanisms: The involvement of charged amino acids from the transmembrane domains of the human dopamine transporter Eur J Pharmacol 538 2006 43 47
16. R. Chen, D.D. Han, and H.H. Gu A triple mutation in the second transmembrane domain of mouse dopamine transporter markedly decreases sensitivity to cocaine and methylphenidate J Neurochem 94 2005 352 359
17. M. Thomsen, D.D. Han, H.H. Gu, and S.B. Caine Lack of cocaine self-administration in mice expressing a cocaine-insensitive dopamine transporter J Pharmacol Exp Ther 331 2009 204 211
18. Y. Mateo, C.M. Lack, D. Morgan, D.C.S. Roberts, and S.R. Jones Reduced dopamine terminal function and insensitivity to cocaine following cocaine binge self-administration and deprivation Neuropsychopharmacology 30 2005 1455 1463
19. N.R. Richardson, and D.C.S. Roberts Progressive ratio schedules in drug self-administration studies in rats: A method to evaluate reinforcing efficacy J Neurosci Methods 66 1996 1 11
20. R.T. Kennedy, S.R. Jones, and R.M. Wightman Dynamic observation of dopamine autoreceptor effects in rat striatal slices J Neurochem 59 1992 449 455
21. C.E. John, E.A. Budygin, Y. Mateo, and S.R. Jones Neurochemical characterization of the release and uptake of dopamine in ventral tegmental area and serotonin in substantia nigra of the mouse J Neurochem 96 2006 267 282
22. R.M. Wightman, C. Amatore, R.C. Engstrom, P.D. Hale, E.W. Kristensen, W.G. Kuhr, and L.J. May Real-time characterization of dopamine overflow and uptake in the rat striatum Neuroscience 25 1988 513 523
23. Y.L. Hurd, F. Weiss, G.F. Koob, N.E. And, and U. Ungerstedt Cocaine reinforcement and extracellular dopamine overflow in rat nucleus accumbensan in vivo microdialysis study Brain Res 498 1989 199 203
24. L.C. Daws, P.D. Callaghan, J.A. Moron, K.M. Kahlig, T.S. Shippenberg, J.A. Javitch, and A. Galli Cocaine increases dopamine uptake and cell surface expression of dopamine transporters Biochem Biophys Res Commun 290 2002 1545 1550
25. N.H. Chen, and M.E.A. Reith Substrates and inhibitors display different sensitivity to expression level of the dopamine transporter in heterologously expressing cells J Neurochem 101 2007 377 388
26. O. Ben Shahar, J.M. Moscarello, and A. Ettenberg One hour, but not six hours, of daily access to self-administered cocaine results in elevated levels of the dopamine transporter Brain Res 1095 2006 148 153
27. K.Y. Little, L.W. Elmer, H.L. Zhong, J.O. Scheys, and L. Zhang Cocaine induction of dopamine transporter trafficking to the plasma membrane Mol Pharmacol 61 2002 436 445
28. S.R. Letchworth, M.A. Nader, H.R. Smith, D.P. Friedman, and L.J. Porrino Progression of changes in dopamine transporter binding site density as a result of cocaine self-administration in rhesus monkeys J Neurosci 21 2001 2799 2807
29. R. Chen, M.R. Tilley, H. Wei, F.W. Zhou, F.M. Zhou, and S. Ching Abolished cocaine reward in mice with a cocaine-insensitive dopamine transporter Proc Natl Acad Sci U S A 103 2006 9333 9338
30. N.D. Volkow, G.J. Wang, J.S. Fowler, S.J. Gatley, Y.S. Ding, and J. Logan Relationship between psychostimulant-induced "high" and dopamine transporter occupancy Proc Natl Acad Sci U S A 93 1996 10388 10392
31. C.A. Dackis, and C.P. O'Brien Cocaine dependence: A disease of the brain's reward centers J Subst Abuse Treat 21 2001 111 117
32. N.D. Volkow, J.S. Fowler, and G.J. Wang Imaging studies on the role of dopamine in cocaine reinforcement and addiction in humans J Psychopharmacol 13 1999 337 345
33. G.J. Wang, N.D. Volkow, J.S. Fowler, J. Logan, N.R. Pappas, and C.T. Wong Reproducibility of repeated measures of endogenous dopamine competition with [C-11]raclopride in the human brain in response to methylphenidate J Nucl Med 40 1999 1285 1291
34. S.H. Ahmed, and G.F. Koob Transition from moderate to excessive drug intake: Change in hedonic set point Science 282 1998 298 300
35. R.A. Yokel, and R.A. Wise Increased lever pressing for amphetamine after pimozide in ratsimplications for a dopamine theory of reward Science 187 1975 547 549
36. R.A. Yokel, and R.A. Wise Attenuation of intravenous amphetamine reinforcement by central dopamine blockade in rats Psychopharmacology (Berl) 48 1976 311 318
37. J.M. Arnold, and D.C.S. Roberts A critique of fixed and progressive ratio schedules used to examine the neural substrates of drug reinforcement Pharmacol Biochem Behav 57 1997 441 447
38. G.F. Koob, and M. Le Moal Drug addiction, dysregulation of reward, and allostasis Neuropsychopharmacology 24 2001 97 129
39. T. Beuming, J. Kniazeff, M.L. Bergmann, L. Shi, L. Gracia, and K. Raniszewska The binding sites for cocaine and dopamine in the dopamine transporter overlap Nat Neurosci 11 2008 780 789
40. Y.J. Liang, J. Zhen, N.H. Chen, and M.E.A. Reith Interaction of catechol and non-catechol substrates with externally or internally facing dopamine transporters J Neurochem 109 2009 981 994
41. L.B. Li, N. Chen, S. Ramamoorthy, L. Chi, X.N. Cui, L.C. Wang, and M.E. Reith The role of N-glycosylation in function and surface trafficking of the human dopamine transporter J Biol Chem 279 2004 21012 21020
42. J.M. Gulley, and N.R. Zahniser Rapid regulation of dopamine transporter function by substrates, blockers and presynaptic receptor ligands Eur J Pharmacol 479 2003 139 152