Allergic inflammation does not impact chemical-induced carcinogenesis in the lungs of mice

Respiratory Research

Volumn 11, Issue , 2010, Pages

  Doris, Konstantinos ^a   Karabela, Sophia P ^a   Kairi, Chrysoula A ^a   Simoes, Davina C M ^a   Roussos, Charis ^a   Zakynthinos, Spyros G ^a   Kalomenidis, Ioannis ^a,b   Blackwell, Timothy S ^c   Stathopoulos, Georgios T ^a,c,d  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

^c VANDERBILT UNIVERSITY   (United States)

^d UNIVERSITY OF PATRAS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 5; OVALBUMIN; URETHAN;

ADENOMA; ANIMAL TISSUE; ARTICLE; ASTHMA; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; DISEASE ASSOCIATION; EOSINOPHILIA; HISTOLOGY; HYPERPLASIA; INFLAMMATORY CELL; LUNG ADENOCARCINOMA; LUNG CARCINOGENESIS; LUNG TUMOR; MOUSE; NONHUMAN; TUMOR GROWTH; TUMOR VOLUME; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CARCINOGEN TESTING; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; CYTOLOGY; DISEASE MODEL; DRUG EFFECT; IMMUNOLOGY; LUNG; LUNG LAVAGE; METHODOLOGY; MOUSE MUTANT; PATHOLOGY; RANDOMIZATION; RESPIRATORY TRACT ALLERGY;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CARCINOGENICITY TESTS; DISEASE MODELS, ANIMAL; LUNG; LUNG NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; RANDOM ALLOCATION; RESPIRATORY HYPERSENSITIVITY; URETHANE;

EID: 78650839760     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-11-118     Document Type: Article

References (46)

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2008. CA Cancer J Clin 2008, 58:71-96. 10.3322/CA.2007.0010, 18287387.
2. Doll R, Peto R. Cigarette smoking and bronchial carcinoma: dose and time relationships among regular smokers and lifelong non-smokers. J Epidemiol Commun Health 1978, 32:303-313.
3. Peto R, Lopez AD, Boreham J, Thun M. Mortality from Smoking in Developed Countries 1950-2000 2006, Oxford: Oxford University Press., http://www.ctsu.ox.ac.uk/~tobacco
4. Subramanian J, Govindan R. Molecular genetics of lung cancer in people who have never smoked. Lancet Oncol 2008, 9:676-682. 10.1016/S1470-2045(08)70174-8, 18598932.
5. Sun S, Schiller JH, Gazdar AF. Lung cancer in never smokers-a different disease. Nat Rev Cancer 2007, 7:778-790. 10.1038/nrc2190, 17882278.
6. Henschke CI, Yankelevitz DF, Libby DM, Pasmantier MW, Smith JP, Miettinen OS. International Early Lung Cancer Action Program Investigators Survival of patients with stage I lung cancer detected on CT screening. N Engl J Med 2006, 355:1763-1771. 10.1056/NEJMoa060476, 17065637, International Early Lung Cancer Action Program Investigators.
7. Pikarsky E, Porat RM, Stein I, Abramovitch R, Amit S, Kasem S, Gutkovich-Pyest E, Urieli-Shoval S, Galun E, Ben-Neriah Y. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature 2004, 431:461-466. 10.1038/nature02924, 15329734.
8. Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, Egan LJ, Kagnoff MF, Karin M. IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 2004, 118:285-296. 10.1016/j.cell.2004.07.013, 15294155.
9. Stathopoulos GT, Sherrill TP, Cheng DS, Scoggins RM, Han W, Polosukhin VV, Connelly L, Yull FE, Fingleton B, Blackwell TS. Epithelial Nuclear Factor-κB Activation Promotes Urethane-Induced Lung Carcinogenesis. Proc Natl Acad Sci USA 2007, 104:18514-18519. 10.1073/pnas.0705316104, 2141808, 18000061.
10. Meylan E, Dooley AL, Feldser DM, Shen L, Turk E, Ouyang C, Jacks T. Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma. Nature 2009, 462:104-107. 10.1038/nature08462, 2780341, 19847165.
11. Takahashi H, Ogata H, Nishigaki R, Broide DH, Karin M. Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation. Cancer Cell 2010, 17:89-97. 10.1016/j.ccr.2009.12.008, 20129250.
12. Thiberville L, Salaün M, Lachkar S, Dominique S, Moreno-Swirc S, Vever-Bizet C, Bourg-Heckly G. Human in vivo fluorescence microimaging of the alveolar ducts and sacs during bronchoscopy. Eur Respir J 2009, 33:974-985. 10.1183/09031936.00083708, 19213792.
13. Burgel PR, Nadel JA. Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases. Eur Respir J 2008, 32:1068-1081. 10.1183/09031936.00172007, 18827153.
14. Curtis JL, Freeman CM, Hogg JC. The Immunopathogenesis of Chronic Obstructive Pulmonary Disease. Insights from Recent Research. Proc Am Thorac Soc 2007, 4:512-521. 10.1513/pats.200701-002FM, 2365762,2365762, 17878463.
15. Hogg JC. Pathophysiology of airflow limitation in chronic obstructive pulmonary disease. Lancet 2004, 364:709-721. 10.1016/S0140-6736(04)16900-6, 15325838.
16. Boffetta P, Ye W, Boman G, Nyrén O. Lung cancer risk in a population-based cohort of patients hospitalized for asthma in Sweden. Eur Respir J 2002, 19:127-133. 10.1183/09031936.02.00245802, 11843311.
17. Santillan AA, Camargo CA, Colditz GA. A meta-analysis of asthma and risk of lung cancer (United States). Cancer Causes Control 2003, 14:327-334. 10.1023/A:1023982402137, 12846363.
18. Brown DW, Young KE, Anda RF, Felitti VJ, Giles WH. Re: asthma and the risk of lung cancer. findings from the Adverse Childhood Experiences (ACE). Cancer Causes Control 2006, 17:349-350. 10.1007/s10552-005-0420-5, 16489542.
19. Seow A, Ng DP, Choo S, Eng P, Poh WT, Ming T, Wang YT. Joint effect of asthma/atopy and an IL-6 gene polymorphism on lung cancer risk among lifetime non-smoking Chinese women. Carcinogenesis 2006, 27:1240-1244. 10.1093/carcin/bgi309, 16344268.
20. Brown DW, Young KE, Anda RF, Giles WH. Asthma and risk of death from lung cancer: NHANES II Mortality Study. J Asthma 2005, 42:597-600. 10.1080/02770900500216234, 16169796.
21. Xanthou G, Alissafi T, Semitekolou M, Simoes DC, Economidou E, Gaga M, Lambrecht BN, Lloyd CM, Panoutsakopoulou V. Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subsets. Nat Med 2007, 13:570-578. 10.1038/nm1580, 17435770.
22. Lloyd CM. Building better mouse models of asthma. Curr Allergy Asthma Rep 2007, 7:231-236. 10.1007/s11882-007-0077-0, 17448336.
23. Simoes DC, Xanthou G, Petrochilou K, Panoutsakopoulou V, Roussos C, Gratziou C. Osteopontin deficiency protects against airway remodeling and hyper-responsiveness in chronic asthma. Am J Respir Crit Care Med 2009, 179:894-902. 10.1164/rccm.200807-1081OC, 19234104.
24. Malkinson AM. Primary lung tumors in mice: an experimentally manipulable model of human adenocarcinoma. Cancer Res 1992, 52:2670s-2676s.
25. Malkinson AM. Molecular comparison of human and mouse pulmonary adenocarcinomas. Exp Lung Res 1998, 24:541-555. 10.3109/01902149809087385, 9659582.
26. Malkinson AM. Primary lung tumors in mice as an aid for understanding, preventing, and treating human adenocarcinoma of the lung. Lung Cancer 2001, 32:265-279. 10.1016/S0169-5002(00)00232-4, 11390008.
27. Kopf M, Brombacher F, Hodgkin PD, Ramsay AJ, Milbourne EA, Dai WJ, Ovington KS, Behm CA, Köhler G, Young IG, Matthaei KI. IL-5-deficient mice have a developmental defect in CD5+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. Immunity 1996, 4:15-24. 10.1016/S1074-7613(00)80294-0, 8574848.
28. Miller YE, Dwyer-Nield LD, Keith RL, Le M, Franklin WA, Malkinson AM. Induction of a high incidence of lung tumors in C57BL/6 mice with multiple ethyl carbamate injections. Cancer Letters 2003, 198:139-144. 10.1016/S0304-3835(03)00309-4, 12957351.
29. Bernert H, Sekikawa K, Radcliffe RA, Iraqi F, You M, Malkinson AM. Tnfa and Il-10 deficiencies have contrasting effects on lung tumor susceptibility: gender-dependent modulation of IL-10 haploinsufficiency. Mol Carcinog 2003, 38:117-123. 10.1002/mc.10151, 14587096.
30. Holgate ST, Polosa R. Treatment strategies for allergy and asthma. Nat Rev Immunol 2008, 8:218-230. 10.1038/nri2262, 18274559.
31. Hecht SS. Tobacco smoke carcinogens and lung cancer. J Natl Cancer Inst 1999, 91:1194-1210. 10.1093/jnci/91.14.1194, 10413421.
32. Rabe KF, Hurd S, Anzueto A, Barnes PJ, Buist SA, Calverley P, Fukuchi Y, Jenkins C, Rodriguez-Roisin R, van Weel C, Zielinski J. Global Initiative for Chronic Obstructive Lung Disease: global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2007, 176:532-555. 10.1164/rccm.200703-456SO, 17507545.
33. Houghton AM, Mouded M, Shapiro SD. Common origins of lung cancer and COPD. Nat Med 2008, 14:1023-1024. 10.1038/nm1008-1023, 18841139.
34. Tockman MS, Anthonisen NR, Wright EC, Donithan MG. Airways obstruction and the risk for lung cancer. Ann Intern Med 1987, 106:512-518.
35. Skillrud DM, Offord KP, Miller RD. Higher risk of lung cancer in chronic obstructive pulmonary disease: a prospective, matched, controlled study. Ann Intern Med 1986, 105:503-507.
36. Alberg AJ, Ford JG, Samet JM, . American College of Chest Physicians Epidemiology of lung cancer: ACCP evidence-based clinical practice guidelines. Chest 2007, 132:29S-55S. 2, 10.1378/chest.07-1347, 17873159, American College of Chest Physicians.
37. Alberg AJ, Samet JM. Epidemiology of lung cancer. Chest 2003, 123:21S-49S. 10.1378/chest.123.1_suppl.21S, 12527563.
38. The Global Strategy for Asthma Management and Prevention (GINA). , http://www.ginasthma.com/
39. Stathopoulos GT, Sherrill TP, Karabela SP, Goleniewska K, Kalomenidis I, Roussos C, Fingleton B, Yull FE, Peebles RS, Blackwell TS. Host-derived interleukin-5 promotes adenocarcinoma-induced malignant pleural effusion. Am J Respir Crit Care Med 2010, PMID: 20595227..
40. Moghaddam SJ, Li H, Cho SN, Dishop MK, Wistuba II, Ji L, Kurie JM, Dickey BF, DeMayo FJ. Promotion of Lung Carcinogenesis by Chronic Obstructive Pulmonary Disease-Like Airway Inflammation in a K-ras-Induced Mouse Model. Am J Respir Cell Mol Biol 2009, 40:443-453. 10.1165/rcmb.2008-0198OC, 2660561, 18927348.
41. Wahl LM, Kleinman HK. Tumor-associated macrophages as targets for cancer therapy. J Natl Cancer Inst 1998, 90:1583-1584. 10.1093/jnci/90.21.1583, 9811301.
42. Mantovani A. The yin-yang of tumor-associated neutrophils. Cancer Cell 2009, 16:173-174. 10.1016/j.ccr.2009.08.014, 19732714.
43. Cormier SA, Taranova AG, Bedient C, Nguyen T, Protheroe C, Pero R, Dimina D, Ochkur SI, O'Neill K, Colbert D, Lombari TR, Constant S, McGarry MP, Lee JJ, Lee NA. Pivotal Advance: eosinophil infiltration of solid tumors is an early and persistent inflammatory host response. J Leukoc Biol 2006, 79:1131-1139. 10.1189/jlb.0106027, 16617160.
44. Kim IM, Ackerson T, Ramakrishna S, Tretiakova M, Wang IC, Kalin TV, Major ML, Gusarova GA, Yoder HM, Costa RH, Kalinichenko VV. The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer. Cancer Res 2006, 66:2153-2161. 10.1158/0008-5472.CAN-05-3003, 16489016.
45. Sridharan L, Greenland P. Editorial policies and publication bias: the importance of negative studies. Arch Intern Med 2009, 169:1022-1023. 10.1001/archinternmed.2009.100, 19506169.
46. de Abreu MG. Negative studies deserve more attention. Am J Respir Crit Care Med 2006, 173:1414-1415.