Rhythmic beating of stem cell-derived cardiac cells requires dynamic coupling of electrophysiology and Ca cycling

Journal of Molecular and Cellular Cardiology

Volumn 50, Issue 1, 2011, Pages 66-76

  Zahanich, Ihor ^a   Sirenko, Syevda G ^a   Maltseva, Larissa A ^a   Tarasova, Yelena S ^a   Spurgeon, Harold A ^a   Boheler, Kenneth R ^a   Stern, Michael D ^a   Lakatta, Edward G ^a   Maltsev, Victor A ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Biological pacemaker; CAMP; Cardiac differentiation; Embryonic stem cells; Ion currents; Local Calcium release; Protein Kinase A

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CAFFEINE; CALCIUM CHANNEL L TYPE; CALCIUM ION; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLOPIAZONIC ACID; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; NIFEDIPINE; PHOSPHOLAMBAN; RYANODINE; SODIUM CALCIUM EXCHANGE PROTEIN; TETRACAINE; THAPSIGARGIN;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CONTROLLED STUDY; DIASTOLE; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVITY; HEART AUTOMATICITY; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE POTENTIAL; HEART RHYTHM; INHIBITION KINETICS; MOUSE; NERVE CELL EXCITABILITY; NONHUMAN; OSCILLATION; PACEMAKER NERVE CELL; PATCH CLAMP; PRIORITY JOURNAL; SARCOLEMMA; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION; TISSUE ENGINEERING;

ACTION POTENTIALS; ANIMALS; BIOLOGICAL CLOCKS; CALCIUM SIGNALING; CYCLIC AMP; ELECTROPHYSIOLOGY; EMBRYONIC STEM CELLS; MICE; MYOCYTES, CARDIAC; PERIODICITY; SARCOPLASMIC RETICULUM;

EID: 78650835205     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2010.09.018     Document Type: Article

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