메뉴 건너뛰기




Volumn 1123, Issue , 2008, Pages 41-57

The missing link in the mystery of normal automaticity of cardiac pacemaker cells

Author keywords

Calcium; Cardiac pacemaker; Na Ca exchanger; Ryanodine receptor; Sarcoplasmic reticulum

Indexed keywords

CALCIUM; CYCLIC AMP DEPENDENT PROTEIN KINASE; ION CHANNEL; RYANODINE RECEPTOR; SODIUM CALCIUM EXCHANGE PROTEIN;

EID: 41149085528     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1420.006     Document Type: Conference Paper
Times cited : (57)

References (107)
  • 1
    • 0000247174 scopus 로고
    • Ueber den zeitlichen Verlauf der negativen Schwankung des Nervenstroms.
    • in German
    • BERNSTEIN, J. 1868. Ueber den zeitlichen Verlauf der negativen Schwankung des Nervenstroms. Pflugers Arch. 1: 173-207 (in German).
    • (1868) Pflugers Arch , vol.1 , pp. 173-207
    • BERNSTEIN, J.1
  • 3
    • 78651026696 scopus 로고
    • The effect of sodium ions on the electrical activity of the giant axon of the squid
    • HODGKIN, A.L. & B. KATZ. 1949. The effect of sodium ions on the electrical activity of the giant axon of the squid. J. Physiol. 108: 37-77.
    • (1949) J. Physiol , vol.108 , pp. 37-77
    • HODGKIN, A.L.1    KATZ, B.2
  • 4
    • 35649001607 scopus 로고
    • A quantitative description of membrane current and its application to conduction and excitation in nerve
    • HODGKIN, A.L. & A.F. HUXLEY. 1952. A quantitative description of membrane current and its application to conduction and excitation in nerve. J. Physiol. 117: 500-544.
    • (1952) J. Physiol , vol.117 , pp. 500-544
    • HODGKIN, A.L.1    HUXLEY, A.F.2
  • 5
    • 33144463142 scopus 로고    scopus 로고
    • The early years of cellular cardiac electrophysiology and Silvio Weidmann (1921-2005)
    • KLEBER, A.G. et al. 2006. The early years of cellular cardiac electrophysiology and Silvio Weidmann (1921-2005). Heart Rhythm. 3: 353-359.
    • (2006) Heart Rhythm , vol.3 , pp. 353-359
    • KLEBER, A.G.1
  • 6
    • 38849162563 scopus 로고
    • Reactions electroniques du myocarde en function de sur tonus initial.
    • ARVANITAKI, A. et al. 1937. Reactions electroniques du myocarde en function de sur tonus initial. Compt. Rend. Sot. Biol. 124: 165-167.
    • (1937) Compt. Rend. Sot. Biol , vol.124 , pp. 165-167
    • ARVANITAKI, A.1
  • 7
    • 0001539241 scopus 로고
    • The initiation of impulses in cardiac muscle
    • BOZLER, E. 1943. The initiation of impulses in cardiac muscle. Am. J. Physiol. 138: 273-282.
    • (1943) Am. J. Physiol , vol.138 , pp. 273-282
    • BOZLER, E.1
  • 8
    • 0012016053 scopus 로고
    • Tonus changes in cardiac muscle and their significance for the initiation of impulses
    • BOZLER, E. 1943. Tonus changes in cardiac muscle and their significance for the initiation of impulses. Am. J. Physiol. 139: 477-480.
    • (1943) Am. J. Physiol , vol.139 , pp. 477-480
    • BOZLER, E.1
  • 9
    • 33750229959 scopus 로고
    • On the origin of the heart beat
    • BRADY, A.J. & H.H. HECHT. 1954. On the origin of the heart beat. Am. J. Med. 17: 110.
    • (1954) Am. J. Med , vol.17 , pp. 110
    • BRADY, A.J.1    HECHT, H.H.2
  • 10
    • 14444285103 scopus 로고
    • Temperature effects on the electrical activity of Purkinje fibres
    • CORABOEUF, E. & S. WEIDMANN. 1954. Temperature effects on the electrical activity of Purkinje fibres. Helv. Physiol. Pharmacol. Acta 12: 32-41.
    • (1954) Helv. Physiol. Pharmacol. Acta , vol.12 , pp. 32-41
    • CORABOEUF, E.1    WEIDMANN, S.2
  • 11
    • 0001710431 scopus 로고
    • Ultramicroelectrode recording from the cardiac pacemakers
    • WEST, T.C. 1955. Ultramicroelectrode recording from the cardiac pacemakers. J. Pharmacol. Exp. Ther. 115: 283-290.
    • (1955) J. Pharmacol. Exp. Ther , vol.115 , pp. 283-290
    • WEST, T.C.1
  • 12
    • 36949064203 scopus 로고
    • Cardiac action and pacemaker potentials based on the Hodgkin-Huxley equations
    • NOBLE, D. 1960. Cardiac action and pacemaker potentials based on the Hodgkin-Huxley equations. Nature 188: 495-497.
    • (1960) Nature , vol.188 , pp. 495-497
    • NOBLE, D.1
  • 13
    • 73849164199 scopus 로고
    • A modification of the Hodgkin-Huxley equations applicable to Purkinje fibre action and pacemaker potentials
    • NOBLE, D. 1962. A modification of the Hodgkin-Huxley equations applicable to Purkinje fibre action and pacemaker potentials. J. Physiol. 160: 317-352.
    • (1962) J. Physiol , vol.160 , pp. 317-352
    • NOBLE, D.1
  • 14
    • 76949111722 scopus 로고
    • Effect of current flow on the membrane potential of cardiac muscle
    • WEIDMANN, S. 1951. Effect of current flow on the membrane potential of cardiac muscle. J. Physiol. 115: 227-236.
    • (1951) J. Physiol , vol.115 , pp. 227-236
    • WEIDMANN, S.1
  • 15
    • 33750236800 scopus 로고
    • The mechanism of formation of automatic rhythmical impulses in heart muscle
    • DUDEL, J. & W. TRAUTWEIN. 1958. The mechanism of formation of automatic rhythmical impulses in heart muscle. Pflugers Arch. 267: 553-565.
    • (1958) Pflugers Arch , vol.267 , pp. 553-565
    • DUDEL, J.1    TRAUTWEIN, W.2
  • 16
    • 0021284516 scopus 로고
    • The surprising heart: A review of recent progress in cardiac electrophysiology
    • NOBLE, D. 1984. The surprising heart: a review of recent progress in cardiac electrophysiology. J. Physiol. 353: 1-50.
    • (1984) J. Physiol , vol.353 , pp. 1-50
    • NOBLE, D.1
  • 18
    • 0018910452 scopus 로고
    • Electrical properties of individual cells isolated from adult rat ventricular myocardium
    • POWELL, T., D.A. TERRAR & V.W. TWIST. 1980. Electrical properties of individual cells isolated from adult rat ventricular myocardium. J. Physiol 302: 131-153.
    • (1980) J. Physiol , vol.302 , pp. 131-153
    • POWELL, T.1    TERRAR, D.A.2    TWIST, V.W.3
  • 20
    • 0019844505 scopus 로고
    • Spontaneously active cells isolated from the sino-atrial and atrio-ventricular nodes of the rabbit heart
    • TANIGUCHI, J. et al. 1981. Spontaneously active cells isolated from the sino-atrial and atrio-ventricular nodes of the rabbit heart. Jpn. J. Physiol. 31: 547-558.
    • (1981) Jpn. J. Physiol , vol.31 , pp. 547-558
    • TANIGUCHI, J.1
  • 21
    • 0027509511 scopus 로고
    • Cardiac pacemaking in the sinoatrial node
    • IRISAWA, H., H.F. BROWN & W. GILES. 1993. Cardiac pacemaking in the sinoatrial node. Physiol.Rev. 73: 197-227.
    • (1993) Physiol.Rev , vol.73 , pp. 197-227
    • IRISAWA, H.1    BROWN, H.F.2    GILES, W.3
  • 22
    • 33847170518 scopus 로고    scopus 로고
    • Computer modelling of the sinoatrial node
    • WILDERS, R. 2007. Computer modelling of the sinoatrial node. Med. Biol. Eng. Comput. 45: 189-207.
    • (2007) Med. Biol. Eng. Comput , vol.45 , pp. 189-207
    • WILDERS, R.1
  • 23
    • 0014001005 scopus 로고
    • Current-tension relations of Purkinje fibers in different extracellular concentrations of calcium and under the influence of adrenaline]
    • REUTER, H. 1966. [Current-tension relations of Purkinje fibers in different extracellular concentrations of calcium and under the influence of adrenaline]. Pflugers Arch. Gesamte Physiol. Menschen Tiere 287: 357-367.
    • (1966) Pflugers Arch. Gesamte Physiol. Menschen Tiere , vol.287 , pp. 357-367
    • REUTER, H.1
  • 24
    • 0019172427 scopus 로고
    • Properties of the current if in the sino-atrial node of the rabbit compared with those of the current iK, in Purkinje fibres
    • DIFRANCESCO, D. & C. OJEDA. 1980. Properties of the current if in the sino-atrial node of the rabbit compared with those of the current iK, in Purkinje fibres. J. Physiol. 308: 353-367.
    • (1980) J. Physiol , vol.308 , pp. 353-367
    • DIFRANCESCO, D.1    OJEDA, C.2
  • 25
    • 0016826011 scopus 로고
    • Reconstruction of the electrical activity of cardiac Purkinje fibres
    • MCALLISTER, R.E., D. NOBLE & R.W. TSIEN. 1975. Reconstruction of the electrical activity of cardiac Purkinje fibres. J. Physiol. 251: 1-59.
    • (1975) J. Physiol , vol.251 , pp. 1-59
    • MCALLISTER, R.E.1    NOBLE, D.2    TSIEN, R.W.3
  • 26
    • 33747586784 scopus 로고    scopus 로고
    • The emergence of a general theory of the initiation and strength of the heartbeat
    • MALTSEV, V.A., T.M. VINOGRADOVA & E.G. LAKATTA. 2006. The emergence of a general theory of the initiation and strength of the heartbeat. J. Pharmacol. Sci. 100: 338-369.
    • (2006) J. Pharmacol. Sci , vol.100 , pp. 338-369
    • MALTSEV, V.A.1    VINOGRADOVA, T.M.2    LAKATTA, E.G.3
  • 27
    • 0017258698 scopus 로고
    • Single-channel currents recorded from membrane of denervated frog muscle fibres
    • NEHER, E. & B. SAKMANN. 1976. Single-channel currents recorded from membrane of denervated frog muscle fibres. Nature 260: 799-802.
    • (1976) Nature , vol.260 , pp. 799-802
    • NEHER, E.1    SAKMANN, B.2
  • 28
    • 0347624077 scopus 로고    scopus 로고
    • Sino-atrial nodal cells of mammalian hearts: Ionic currents and gene expression of pacemaker ionic channels
    • SATOH, H. 2003. Sino-atrial nodal cells of mammalian hearts: ionic currents and gene expression of pacemaker ionic channels. J. Smooth Muscle Res. 39: 175-193.
    • (2003) J. Smooth Muscle Res , vol.39 , pp. 175-193
    • SATOH, H.1
  • 29
    • 0029093231 scopus 로고
    • The pacemaker current (If) does not play an important role in regulating SA node pacemaker activity
    • VASSALLE, M. 1995. The pacemaker current (If) does not play an important role in regulating SA node pacemaker activity. Cardiovasc. Res. 30: 309-310.
    • (1995) Cardiovasc. Res , vol.30 , pp. 309-310
    • VASSALLE, M.1
  • 30
    • 33750272793 scopus 로고
    • The relative contributions of various time-dependent membrane currents to pacemaker activity in the sino atrial node
    • L.N. Bouman & H.J. Jongsma, Eds, Martinus Nijhoff. The Hague
    • BROWN, H., J. KIMURA & S. NOBLE. 1982. The relative contributions of various time-dependent membrane currents to pacemaker activity in the sino atrial node. In Cardiac Rate and Rhythm. L.N. Bouman & H.J. Jongsma, Eds.: 53-68. Martinus Nijhoff. The Hague.
    • (1982) Cardiac Rate and Rhythm , pp. 53-68
    • BROWN, H.1    KIMURA, J.2    NOBLE, S.3
  • 31
    • 0346564097 scopus 로고
    • Ionic currents that generate the spontaneous diastolic depolarization in individual cardiac pacemaker cells
    • SHIBATA, E.F. & W.R. GILES. 1985. Ionic currents that generate the spontaneous diastolic depolarization in individual cardiac pacemaker cells. Proc. Natl. Acad. Sci. USA 82: 7796-7800.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 7796-7800
    • SHIBATA, E.F.1    GILES, W.R.2
  • 32
    • 28044464474 scopus 로고    scopus 로고
    • 2+ channels in cardiac pacemaking
    • 2+ channels in cardiac pacemaking. J. Pharmacol. Sci. 99: 197-204.
    • (2005) J. Pharmacol. Sci , vol.99 , pp. 197-204
    • ONO, K.1    IIJIMA, T.2
  • 33
    • 0036554705 scopus 로고    scopus 로고
    • - current in rabbit sinoatrial node cells
    • - current in rabbit sinoatrial node cells. J. Physiol. 540: 105-17.
    • (2002) J. Physiol , vol.540 , pp. 105-117
    • VERKERK, A.O.1
  • 34
    • 0028913302 scopus 로고
    • A sustained inward current activated at the diastolic potential range in rabbit sino-atrial node cells
    • GUO, J., K. ONO & A. NOMA. 1995. A sustained inward current activated at the diastolic potential range in rabbit sino-atrial node cells. J. Physiol. 483(Pt 1): 1-13.
    • (1995) J. Physiol , vol.483 , Issue.PART 1 , pp. 1-13
    • GUO, J.1    ONO, K.2    NOMA, A.3
  • 35
    • 0021132203 scopus 로고
    • The ionic currents underlying pacemaker activity in rabbit sino-atrial node: Experimental results and computer simulations
    • BROWN, H.F. et al. 1984. The ionic currents underlying pacemaker activity in rabbit sino-atrial node: experimental results and computer simulations. Proc. R. Soc. Lond. B Biol. Sci. 222: 329-347.
    • (1984) Proc. R. Soc. Lond. B Biol. Sci , vol.222 , pp. 329-347
    • BROWN, H.F.1
  • 36
    • 0031574245 scopus 로고    scopus 로고
    • Ionic currents during sustained pacemaker activity in rabbit sino-atrial myocytes
    • ZAZA, A. et al. 1997. Ionic currents during sustained pacemaker activity in rabbit sino-atrial myocytes. J. Physiol. 505(Pt 3): 677-688.
    • (1997) J. Physiol , vol.505 , Issue.PART 3 , pp. 677-688
    • ZAZA, A.1
  • 37
    • 0028895513 scopus 로고
    • Role of rapidly activating delayed rectifier K+ current in sinoatrial node pacemaker activity
    • ONO, K. & H. ITO. 1995. Role of rapidly activating delayed rectifier K+ current in sinoatrial node pacemaker activity. Am. J. Physiol. 269: H453-462.
    • (1995) Am. J. Physiol , vol.269
    • ONO, K.1    ITO, H.2
  • 38
    • 0019277122 scopus 로고
    • Reconstruction of sino-atrial node pacemaker potential based on the voltage clamp experiments
    • YANAGIHARA, K., A. NOMA & H. IRISAWA. 1980. Reconstruction of sino-atrial node pacemaker potential based on the voltage clamp experiments. Jpn. J. Physiol. 30: 841-857.
    • (1980) Jpn. J. Physiol , vol.30 , pp. 841-857
    • YANAGIHARA, K.1    NOMA, A.2    IRISAWA, H.3
  • 39
    • 0019524947 scopus 로고
    • A study of pacemaker potential in rabbit sino-atrial node: Measurement of potassium activity under voltage-clamp conditions
    • MAYLIE, J., M. MORAD & J. WEISS. 1981. A study of pacemaker potential in rabbit sino-atrial node: measurement of potassium activity under voltage-clamp conditions. J. Physiol. 311: 161-178.
    • (1981) J. Physiol , vol.311 , pp. 161-178
    • MAYLIE, J.1    MORAD, M.2    WEISS, J.3
  • 40
    • 0025977991 scopus 로고
    • The contribution of the 'pacemaker' current (if) to generation of spontaneous activity in rabbit sino-atrial node myocytes
    • DIFRANCESCO, D. 1991. The contribution of the 'pacemaker' current (if) to generation of spontaneous activity in rabbit sino-atrial node myocytes. J. Physiol. 434: 23-40.
    • (1991) J. Physiol , vol.434 , pp. 23-40
    • DIFRANCESCO, D.1
  • 41
    • 0022495261 scopus 로고
    • Possible functional significance of a novel type of cardiac Ca channel
    • NILIUS, B. 1986. Possible functional significance of a novel type of cardiac Ca channel. Biomed Biochim Acta 45: K37-45.
    • (1986) Biomed Biochim Acta , vol.45
    • NILIUS, B.1
  • 42
    • 0029741590 scopus 로고    scopus 로고
    • Possible role of calcium release from the sarcoplasmic reticulum in pacemaking in guinea-pig sino-atrial node
    • RIGG, L. & D.A. TERRAR. 1996. Possible role of calcium release from the sarcoplasmic reticulum in pacemaking in guinea-pig sino-atrial node. Exp. Physiol. 81: 877-880.
    • (1996) Exp. Physiol , vol.81 , pp. 877-880
    • RIGG, L.1    TERRAR, D.A.2
  • 43
    • 0030725925 scopus 로고    scopus 로고
    • Ionic basis of ryanodine's negative chronotropic effect on pacemaker cells isolated from the sinoatrial node
    • LI, J., J. QU & R.D. NATHAN. 1997. Ionic basis of ryanodine's negative chronotropic effect on pacemaker cells isolated from the sinoatrial node. Am. J. Physiol. 273: H2481-2489.
    • (1997) Am. J. Physiol , vol.273
    • LI, J.1    QU, J.2    NATHAN, R.D.3
  • 44
    • 0031012374 scopus 로고    scopus 로고
    • Electrophysiological actions of ryanodine on single rabbit sinoatrial nodal cells
    • SATOH, H. 1997. Electrophysiological actions of ryanodine on single rabbit sinoatrial nodal cells. Gen. Pharmacol. 28: 31-38.
    • (1997) Gen. Pharmacol , vol.28 , pp. 31-38
    • SATOH, H.1
  • 45
    • 84944811856 scopus 로고
    • A further contribution regarding the influence of the different constituents of the blood on the contraction of the heart
    • RINGER, S. 1883. A further contribution regarding the influence of the different constituents of the blood on the contraction of the heart. J. Physiol. 4: 29-42.
    • (1883) J. Physiol , vol.4 , pp. 29-42
    • RINGER, S.1
  • 47
    • 0018361364 scopus 로고
    • Ryanodine: Its alterations of cat papillary muscle contractile state and responsiveness to inotropic interventions and a suggested mechanism of action
    • SUTKO, J.L. et al. 1979. Ryanodine: its alterations of cat papillary muscle contractile state and responsiveness to inotropic interventions and a suggested mechanism of action. J. Pharmacol. Exp. Ther. 209: 37-47.
    • (1979) J. Pharmacol. Exp. Ther , vol.209 , pp. 37-47
    • SUTKO, J.L.1
  • 48
    • 0018866614 scopus 로고
    • Ryanodine alteration of the contractile state of rat ventricular myocardium. Comparison with dog, cat, and rabbit ventricular tissues
    • SUTKO, J.L. & J.T. WILLERSON. 1980. Ryanodine alteration of the contractile state of rat ventricular myocardium. Comparison with dog, cat, and rabbit ventricular tissues. Circ. Res. 46: 332-343.
    • (1980) Circ. Res , vol.46 , pp. 332-343
    • SUTKO, J.L.1    WILLERSON, J.T.2
  • 49
    • 79953318582 scopus 로고
    • Historical note on the translation of H.P. Bowditch's paper' Über die Eigenthümlichkeiten der Reizbarkeit, welche die Muskelfasern des Herzens zeigen' (On the peculiarities of excitability which the fibres of cardiac muscle show)
    • M. Noble & W.A. Seed, Eds. Cambridge University Press. Cambridge
    • SCHAEFER, J. et al. 1992. Historical note on the translation of H.P. Bowditch's paper' Über die Eigenthümlichkeiten der Reizbarkeit, welche die Muskelfasern des Herzens zeigen' (On the peculiarities of excitability which the fibres of cardiac muscle show). In The Interval-Force Relationship of the Heart: Bowditch revisited. M. Noble & W.A. Seed, Eds. Cambridge University Press. Cambridge.
    • (1992) The Interval-Force Relationship of the Heart: Bowditch revisited
    • SCHAEFER, J.1
  • 50
    • 0014478314 scopus 로고
    • Inotropic effects of electric currents. I. Positive and negative effects of constant electric currents or current pulses applied during cardiac action potentials. II. Hypotheses: Calcium movements, excitation-contraction coupling and inotropic effects
    • WOOD, E.H., R.L. HEPPNER & S. WEIDMANN. 1969. Inotropic effects of electric currents. I. Positive and negative effects of constant electric currents or current pulses applied during cardiac action potentials. II. Hypotheses: calcium movements, excitation-contraction coupling and inotropic effects. Circ. Res. 24: 409-445.
    • (1969) Circ. Res , vol.24 , pp. 409-445
    • WOOD, E.H.1    HEPPNER, R.L.2    WEIDMANN, S.3
  • 51
    • 0018278243 scopus 로고    scopus 로고
    • FABIATO, A. & F. FABIATO. 1978. Calcium-induced release of calcium from the sarcoplasmic reticulum of skinned cells from adult human, dog, cat, rabbit, rat, and frog hearts and from fetal and new-born rat ventricles. Ann. N.Y. Acad. Sci. 307: 491-522.
    • FABIATO, A. & F. FABIATO. 1978. Calcium-induced release of calcium from the sarcoplasmic reticulum of skinned cells from adult human, dog, cat, rabbit, rat, and frog hearts and from fetal and new-born rat ventricles. Ann. N.Y. Acad. Sci. 307: 491-522.
  • 52
    • 0015403041 scopus 로고
    • Excitation-contraction coupling of isolated cardiac fibers with disrupted or closed sarcolemmas. Calcium-dependent cyclic and tonic contractions
    • FABIATO, A. & F. FABIATO. 1972. Excitation-contraction coupling of isolated cardiac fibers with disrupted or closed sarcolemmas. Calcium-dependent cyclic and tonic contractions. Circ. Res. 31: 293-307.
    • (1972) Circ. Res , vol.31 , pp. 293-307
    • FABIATO, A.1    FABIATO, F.2
  • 53
    • 0018149737 scopus 로고
    • Calcium transients in aequorin-injected frog cardiacmuscle
    • ALLEN, D.G. & J.R. BLINKS. 1978. Calcium transients in aequorin-injected frog cardiacmuscle. Nature 273: 509-513.
    • (1978) Nature , vol.273 , pp. 509-513
    • ALLEN, D.G.1    BLINKS, J.R.2
  • 54
    • 0018873018 scopus 로고
    • Calcium transients during excitationcontraction coupling in mammalian heart: Aequorin signals of canine Purkinje fibers
    • WIER, W.G. 1980. Calcium transients during excitationcontraction coupling in mammalian heart: aequorin signals of canine Purkinje fibers. Science 207: 1085-1087.
    • (1980) Science , vol.207 , pp. 1085-1087
    • WIER, W.G.1
  • 55
    • 0021686007 scopus 로고
    • The effects of shortening on myoplasmic calcium concentration and on the action potential in mammalian ventricular muscle
    • LAB, M.J., D.G. ALLEN & C.H. ORCHARD. 1984. The effects of shortening on myoplasmic calcium concentration and on the action potential in mammalian ventricular muscle. Circ. Res. 55: 825-829.
    • (1984) Circ. Res , vol.55 , pp. 825-829
    • LAB, M.J.1    ALLEN, D.G.2    ORCHARD, C.H.3
  • 56
    • 0025828731 scopus 로고
    • The cytosolic calcium transient modulates the action potential of rat ventricular myocytes
    • DUBELL, W.H. et al. 1991. The cytosolic calcium transient modulates the action potential of rat ventricular myocytes. J. Physiol. 436: 347-369.
    • (1991) J. Physiol , vol.436 , pp. 347-369
    • DUBELL, W.H.1
  • 57
    • 0017695423 scopus 로고
    • Action potentials, after potentials, and arrhythmias
    • CRANEFIELD, P.F. 1977. Action potentials, after potentials, and arrhythmias. Circ. Res. 41: 415-423.
    • (1977) Circ. Res , vol.41 , pp. 415-423
    • CRANEFIELD, P.F.1
  • 58
    • 0018502516 scopus 로고
    • Cellular and subcellular mechanisms of cardiac pacemaker oscillations
    • TSIEN, R.W., R.S. KASS & R. WEINGART. 1979. Cellular and subcellular mechanisms of cardiac pacemaker oscillations. J. Exp. Biol. 81: 205-215.
    • (1979) J. Exp. Biol , vol.81 , pp. 205-215
    • TSIEN, R.W.1    KASS, R.S.2    WEINGART, R.3
  • 59
    • 84944818284 scopus 로고
    • On the innervation of the heart, with special reference to the heart of the tortoise
    • GASKELL, W.H. 1881. On the innervation of the heart, with special reference to the heart of the tortoise. J. Physiol. 4: 43-127.
    • (1881) J. Physiol , vol.4 , pp. 43-127
    • GASKELL, W.H.1
  • 61
    • 0015581366 scopus 로고
    • Effect of changes in cycle length on diastolic depolarization produced by ouabain in canine Purkinje fibers
    • DAVIS, L.D. 1973. Effect of changes in cycle length on diastolic depolarization produced by ouabain in canine Purkinje fibers. Circ. Res. 32: 206-214.
    • (1973) Circ. Res , vol.32 , pp. 206-214
    • DAVIS, L.D.1
  • 62
    • 0015545322 scopus 로고
    • Correlation between effects of ouabain on the canine electrocardiogram and transmembrane potentials of isolated Purkinje fibers
    • ROSEN, M.R., H. GELBAND & B.F. HOFFMAN. 1973. Correlation between effects of ouabain on the canine electrocardiogram and transmembrane potentials of isolated Purkinje fibers. Circulation 47: 65-72.
    • (1973) Circulation , vol.47 , pp. 65-72
    • ROSEN, M.R.1    GELBAND, H.2    HOFFMAN, B.F.3
  • 63
    • 0015622510 scopus 로고
    • A cellular mechanism for the generation of ventricular arrhythmias by acetylstrophanthidin
    • FERRIER, G.R., J.H. SAUNDERS & C. MENDEZ. 1973. A cellular mechanism for the generation of ventricular arrhythmias by acetylstrophanthidin. Circ. Res. 32: 600-609.
    • (1973) Circ. Res , vol.32 , pp. 600-609
    • FERRIER, G.R.1    SAUNDERS, J.H.2    MENDEZ, C.3
  • 64
    • 0015894415 scopus 로고
    • Effect of calcium on acetylstrophanthidin-induced transient depolarizations in canine Purkinje tissue
    • FERRIER, G.R. & G.K. MOE. 1973. Effect of calcium on acetylstrophanthidin-induced transient depolarizations in canine Purkinje tissue. Circ. Res. 33: 508-515.
    • (1973) Circ. Res , vol.33 , pp. 508-515
    • FERRIER, G.R.1    MOE, G.K.2
  • 65
    • 33750254010 scopus 로고
    • Causes and Conditions of Release of Myocardial Contractions without a Regular Action Potential]
    • in German
    • KAUFMANN, R., A. FLECKENSTEIN & H. ANTONI. 1963. [Causes and Conditions of Release of Myocardial Contractions without a Regular Action Potential]. Pflugers Arch. Gesamte Physiol. Menschen Tiere 278: 435-446 (in German).
    • (1963) Pflugers Arch. Gesamte Physiol. Menschen Tiere , vol.278 , pp. 435-446
    • KAUFMANN, R.1    FLECKENSTEIN, A.2    ANTONI, H.3
  • 66
    • 0017714653 scopus 로고
    • Electro-mechanical noise in atrial muscle fibres of the carp
    • AKSELROD, S. et al. 1977. Electro-mechanical noise in atrial muscle fibres of the carp. Experientia 33: 1058-1060.
    • (1977) Experientia , vol.33 , pp. 1058-1060
    • AKSELROD, S.1
  • 67
    • 0017394490 scopus 로고
    • Oscillations in calcium-cyclic AMP control loops form the basis of pacemaker activity and other high frequency biological rhythms
    • RAPP, P.E. & M.J. BERRIDGE. 1977. Oscillations in calcium-cyclic AMP control loops form the basis of pacemaker activity and other high frequency biological rhythms. J. Theor. Biol. 66: 497-525.
    • (1977) J. Theor. Biol , vol.66 , pp. 497-525
    • RAPP, P.E.1    BERRIDGE, M.J.2
  • 68
    • 0016768145 scopus 로고
    • Contractions induced by a calcium-triggered release of calcium from the sarcoplasmic reticulum of single skinned cardiac cells
    • FABIATO, A. & F. FABIATO. 1975. Contractions induced by a calcium-triggered release of calcium from the sarcoplasmic reticulum of single skinned cardiac cells. J. Physiol. 249: 469-495.
    • (1975) J. Physiol , vol.249 , pp. 469-495
    • FABIATO, A.1    FABIATO, F.2
  • 69
    • 0016632397 scopus 로고
    • Voltage noise and impedance from heart cell aggregates
    • Abstract
    • DEFELICE, L.J. & R.L. DEHAAN. 1975. Voltage noise and impedance from heart cell aggregates. Biophys. J. 15: 130a (Abstract).
    • (1975) Biophys. J , vol.15
    • DEFELICE, L.J.1    DEHAAN, R.L.2
  • 70
    • 0017031594 scopus 로고
    • Transient inward current underlying arrhythmogenic effects of cardiotonic steroids in Purkinje fibres
    • LEDERER, W.J. & R.W. TSIEN. 1976. Transient inward current underlying arrhythmogenic effects of cardiotonic steroids in Purkinje fibres. J. Physiol. 263: 73-100.
    • (1976) J. Physiol , vol.263 , pp. 73-100
    • LEDERER, W.J.1    TSIEN, R.W.2
  • 71
    • 0017641233 scopus 로고
    • The effect of ouabain, dinitrophenol, and lithium on the pacemaker current in sheep cardiac Purkinje fibers
    • ARONSON, R.S. & J.M. GELLES. 1977. The effect of ouabain, dinitrophenol, and lithium on the pacemaker current in sheep cardiac Purkinje fibers. Circ. Res. 40: 517-524.
    • (1977) Circ. Res , vol.40 , pp. 517-524
    • ARONSON, R.S.1    GELLES, J.M.2
  • 72
    • 0018198761 scopus 로고
    • Role of calcium ions in transient inward currents and aftercontractions induced by strophanthidin in cardiac Purkinje fibres
    • KASS, R.S. et al. 1978. Role of calcium ions in transient inward currents and aftercontractions induced by strophanthidin in cardiac Purkinje fibres. J. Physiol. 281: 187-208.
    • (1978) J. Physiol , vol.281 , pp. 187-208
    • KASS, R.S.1
  • 73
    • 0018651774 scopus 로고
    • Inotropic and arrhythmogenic effects of potassium-depleted solutions on mammalian cardiac muscle
    • EISNER, D.A. & W.J. LEDERER. 1979. Inotropic and arrhythmogenic effects of potassium-depleted solutions on mammalian cardiac muscle. J. Physiol. 294: 255-277.
    • (1979) J. Physiol , vol.294 , pp. 255-277
    • EISNER, D.A.1    LEDERER, W.J.2
  • 74
    • 0019942895 scopus 로고
    • Fluctuations in membrane current driven by intracellular calcium in cardiac Purkinje fibers
    • KASS, R.S. & R.W. TSIEN. 1982. Fluctuations in membrane current driven by intracellular calcium in cardiac Purkinje fibers. Biophys. J. 38: 259-269.
    • (1982) Biophys. J , vol.38 , pp. 259-269
    • KASS, R.S.1    TSIEN, R.W.2
  • 75
    • 33750235323 scopus 로고
    • Voltage clamp of isolated cardiac Purkinje cells
    • Abstract
    • MEHDI, T. & F. SACHS. 1978. Voltage clamp of isolated cardiac Purkinje cells. Biophys. J. 21: 165a (Abstract).
    • (1978) Biophys. J , vol.21
    • MEHDI, T.1    SACHS, F.2
  • 76
    • 0018236437 scopus 로고
    • Comparative physiology of the cardiac pacemaker mechanism
    • IRISAWA, H. 1978. Comparative physiology of the cardiac pacemaker mechanism. Physiol. Rev. 58: 461-498.
    • (1978) Physiol. Rev , vol.58 , pp. 461-498
    • IRISAWA, H.1
  • 77
    • 17444446436 scopus 로고
    • Current fluctuations in strophanthidin-treated cardiac Purkinje fibers
    • Abstract
    • KASS, R.S., W.J. LEDERER & R.W. TSIEN. 1976. Current fluctuations in strophanthidin-treated cardiac Purkinje fibers. Biophys. J. 16: 25a (Abstract).
    • (1976) Biophys. J , vol.16
    • KASS, R.S.1    LEDERER, W.J.2    TSIEN, R.W.3
  • 78
    • 0021014678 scopus 로고
    • Cellular calcium fluctuations in mammalian heart: Direct evidence from noise analysis of aequorin signals in Purkinje fibers
    • WIER, W.G. et al. 1983. Cellular calcium fluctuations in mammalian heart: direct evidence from noise analysis of aequorin signals in Purkinje fibers. Proc. Natl. Acad. Sci. USA 80: 7367-7371.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 7367-7371
    • WIER, W.G.1
  • 79
    • 0022270919 scopus 로고
    • Fluctuations in intracellular calcium concentration and their effect on tonic tension in canine cardiac Purkinje fibres
    • KORT, A.A. et al. 1985. Fluctuations in intracellular calcium concentration and their effect on tonic tension in canine cardiac Purkinje fibres. J. Physiol. 367: 291-308.
    • (1985) J. Physiol , vol.367 , pp. 291-308
    • KORT, A.A.1
  • 80
    • 0027337258 scopus 로고
    • 2+ exchange current in latent pacemaker cells isolated from cat right atrium
    • 2+ exchange current in latent pacemaker cells isolated from cat right atrium. J. Physiol. 466: 263-285.
    • (1993) J. Physiol , vol.466 , pp. 263-285
    • ZHOU, Z.1    LIPSIUS, S.L.2
  • 81
    • 0019947031 scopus 로고
    • Membrane currents, contractions, and aftercontractions in cardiac Purkinje fibers
    • LIPSIUS, S.L. & W.R. GIBBONS. 1982. Membrane currents, contractions, and aftercontractions in cardiac Purkinje fibers. Am. J. Physiol. 243: H77-86.
    • (1982) Am. J. Physiol , vol.243
    • LIPSIUS, S.L.1    GIBBONS, W.R.2
  • 82
    • 0021346594 scopus 로고    scopus 로고
    • KORT, A.A. & E.G. LAKATTA. 1984. Calcium-dependent mechanical oscillations occur spontaneously in unstimulated mammalian cardiac tissues.Circ.Res. 54: 396-404.
    • KORT, A.A. & E.G. LAKATTA. 1984. Calcium-dependent mechanical oscillations occur spontaneously in unstimulated mammalian cardiac tissues.Circ.Res. 54: 396-404.
  • 83
    • 0024505757 scopus 로고
    • Mechanisms of automaticity in subsidiary pacemakers from cat right atrium
    • RUBENSTEIN, D.S. & S.L. LIPSIUS. 1989. Mechanisms of automaticity in subsidiary pacemakers from cat right atrium. Circ. Res. 64: 648-657.
    • (1989) Circ. Res , vol.64 , pp. 648-657
    • RUBENSTEIN, D.S.1    LIPSIUS, S.L.2
  • 84
    • 0033135309 scopus 로고    scopus 로고
    • 2+ release in amphibian pacemaker cells
    • 2+ release in amphibian pacemaker cells. J. Physiol. 516(Pt 3): 793-804.
    • (1999) J. Physiol , vol.516 , Issue.PART 3 , pp. 793-804
    • JU, Y.K.1    ALLEN, D.G.2
  • 85
    • 0033779053 scopus 로고    scopus 로고
    • Localisation and functional significance of ryanodine receptors during beta-adrenoceptor stimulation in the guinea-pig sino-atrial node
    • RIGG, L. et al. 2000. Localisation and functional significance of ryanodine receptors during beta-adrenoceptor stimulation in the guinea-pig sino-atrial node. Cardiovasc. Res. 48: 254-264.
    • (2000) Cardiovasc. Res , vol.48 , pp. 254-264
    • RIGG, L.1
  • 86
    • 0036182464 scopus 로고    scopus 로고
    • 2+ handling proteins in rabbit sinoatrial node
    • 2+ handling proteins in rabbit sinoatrial node. J. Histochem. Cytochem. 50: 311-324.
    • (2002) J. Histochem. Cytochem , vol.50 , pp. 311-324
    • MUSA, H.1
  • 87
    • 0034721798 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II activation
    • 2+/calmodulin-dependent protein kinase II activation. Circ. Res. 87: 760-767.
    • (2000) Circ. Res , vol.87 , pp. 760-767
    • VINOGRADOVA, T.M.1
  • 88
    • 0038267551 scopus 로고    scopus 로고
    • The electrophysiological properties of spontaneously beating pacemaker cells isolated from mouse sinoatrial node
    • CHO, H.S., M. TAKANO & A. NOMA. 2003. The electrophysiological properties of spontaneously beating pacemaker cells isolated from mouse sinoatrial node. J. Physiol. 550: 169-180.
    • (2003) J. Physiol , vol.550 , pp. 169-180
    • CHO, H.S.1    TAKANO, M.2    NOMA, A.3
  • 89
    • 33644701769 scopus 로고    scopus 로고
    • 2+ exchange for the pacemaking mechanism in guinea-pig sino-atrial node
    • 2+ exchange for the pacemaking mechanism in guinea-pig sino-atrial node. J. Physiol. 571: 639-649.
    • (2006) J. Physiol , vol.571 , pp. 639-649
    • SANDERS, L.1
  • 90
    • 0028144693 scopus 로고
    • Intracellular calcium transients recorded with Fura-2 in spontaneously active myocytes isolated from the atrioventricular node of the rabbit heart
    • HANCOX, J.C., A.J. LEVI & P. BROOKSBY. 1994. Intracellular calcium transients recorded with Fura-2 in spontaneously active myocytes isolated from the atrioventricular node of the rabbit heart. Proc. Biol. Sci. 255: 99-105.
    • (1994) Proc. Biol. Sci , vol.255 , pp. 99-105
    • HANCOX, J.C.1    LEVI, A.J.2    BROOKSBY, P.3
  • 91
    • 34250820394 scopus 로고    scopus 로고
    • Calcium cycling protein density and functional importance to automaticity of isolated sinoatrial nodal cells are independent of cell size
    • LYASHKOV, A.E. et al. 2007. Calcium cycling protein density and functional importance to automaticity of isolated sinoatrial nodal cells are independent of cell size. Circ. Res. 100: 1723-1731
    • (2007) Circ. Res , vol.100 , pp. 1723-1731
    • LYASHKOV, A.E.1
  • 92
    • 33750450141 scopus 로고    scopus 로고
    • 2+ releases in rabbit sinoatrial nodal cells impart an exponential phase to the late diastolic depolarization that controls their chronotropic state
    • 2+ releases in rabbit sinoatrial nodal cells impart an exponential phase to the late diastolic depolarization that controls their chronotropic state. Circ. Res. 99: 979-987.
    • (2006) Circ. Res , vol.99 , pp. 979-987
    • BOGDANOV, K.Y.1
  • 93
    • 1842507527 scopus 로고    scopus 로고
    • 2+ releases during diastolic depolarization of sinoatrial pacemaker cells do not require membrane depolarization
    • 2+ releases during diastolic depolarization of sinoatrial pacemaker cells do not require membrane depolarization. Circ. Res. 94: 802-809.
    • (2004) Circ. Res , vol.94 , pp. 802-809
    • VINOGRADOVA, T.M.1
  • 94
    • 33645324479 scopus 로고    scopus 로고
    • 2+ store oscillations and spontaneous beating of cardiac pacemaker cells
    • 2+ store oscillations and spontaneous beating of cardiac pacemaker cells. Circ. Res. 98: 505-514.
    • (2006) Circ. Res , vol.98 , pp. 505-514
    • VINOGRADOVA, T.M.1
  • 95
    • 0029864476 scopus 로고    scopus 로고
    • Ionic mechanisms of the cardiac pacemaker potential
    • NOMA, A. 1996. Ionic mechanisms of the cardiac pacemaker potential. Jpn. Heart J. 37: 673-682.
    • (1996) Jpn. Heart J , vol.37 , pp. 673-682
    • NOMA, A.1
  • 96
    • 33845667862 scopus 로고    scopus 로고
    • 2+ cycling and surface membrane ion channel activation entrains normal automaticity in cells of the heart's pacemaker
    • 2+ cycling and surface membrane ion channel activation entrains normal automaticity in cells of the heart's pacemaker. Ann. N.Y. Acad. Sci. 1080: 178-206.
    • (2006) Ann. N.Y. Acad. Sci , vol.1080 , pp. 178-206
    • LAKATTA, E.G.1
  • 97
    • 0033858925 scopus 로고    scopus 로고
    • Mathematical models of action potentials in the periphery and center of the rabbit sinoatrial node
    • ZHANG, H. et al. 2000. Mathematical models of action potentials in the periphery and center of the rabbit sinoatrial node. Am. J. Physiol. 279: H397-421.
    • (2000) Am. J. Physiol , vol.279
    • ZHANG, H.1
  • 98
    • 0037458671 scopus 로고    scopus 로고
    • Cyclic variation of intracellular calcium: A critical factor for cardiac pacemaker cell dominance
    • LAKATTA, E.G. et al. 2003. Cyclic variation of intracellular calcium: a critical factor for cardiac pacemaker cell dominance. Circ. Res. 92: e45-50.
    • (2003) Circ. Res , vol.92
    • LAKATTA, E.G.1
  • 99
    • 0036838501 scopus 로고    scopus 로고
    • Dynamical description of sinoatrial node pacemaking: Improved mathematical model for primary pacemaker cell
    • KURATA, Y. et al. 2002. Dynamical description of sinoatrial node pacemaking: improved mathematical model for primary pacemaker cell. Am. J. Physiol. 283: H2074-101.
    • (2002) Am. J. Physiol , vol.283
    • KURATA, Y.1
  • 100
    • 1942487269 scopus 로고    scopus 로고
    • Diastolic calcium release controls the beating rate of rabbit sinoatrial node cells: Numerical modeling of the coupling process
    • MALTSEV, V.A. et al. 2004. Diastolic calcium release controls the beating rate of rabbit sinoatrial node cells: numerical modeling of the coupling process. Biophys. J. 86: 2596-2605.
    • (2004) Biophys. J , vol.86 , pp. 2596-2605
    • MALTSEV, V.A.1
  • 101
    • 33645180886 scopus 로고    scopus 로고
    • 2+ releases within rabbit sinoatrial nodal cells not only regulate beating rate but also ensure normal rhythm during protein kinase A inhibition
    • Abstract
    • 2+ releases within rabbit sinoatrial nodal cells not only regulate beating rate but also ensure normal rhythm during protein kinase A inhibition. Biophys. J. 88: 89a-90a (Abstract).
    • (2005) Biophys. J , vol.88
    • MALTSEV, V.A.1
  • 102
    • 41149154735 scopus 로고    scopus 로고
    • 2+ cycling provides a novel mechanism of normal cardiac pacemaker function. Biophys. J. Supplement: 77a (Abstract).
    • 2+ cycling provides a novel mechanism of normal cardiac pacemaker function. Biophys. J. Supplement: 77a (Abstract).
  • 103
    • 41149097421 scopus 로고    scopus 로고
    • 2+ clock within cardiac cells. Biophys. J. Supplement: 344a (Abstract).
    • 2+ clock within cardiac cells. Biophys. J. Supplement: 344a (Abstract).
  • 104
    • 16344373083 scopus 로고    scopus 로고
    • A mathematical treatment of integrated Ca dynamics within the ventricular myocyte
    • SHANNON, T.R. et al. 2004. A mathematical treatment of integrated Ca dynamics within the ventricular myocyte. Biophys. J. 87: 3351-3371.
    • (2004) Biophys. J , vol.87 , pp. 3351-3371
    • SHANNON, T.R.1
  • 105
    • 41149132554 scopus 로고    scopus 로고
    • 2+ releases (LCR) and the spontaneous beating rate of sinoatrial node cells (SANC). Biophys. J. Supplement: 31a (Abstract).
    • 2+ releases (LCR) and the spontaneous beating rate of sinoatrial node cells (SANC). Biophys. J. Supplement: 31a (Abstract).
  • 106
    • 0032955695 scopus 로고    scopus 로고
    • 2+ current to electrical activity in sinoatrial nodal myocytes of rabbits
    • 2+ current to electrical activity in sinoatrial nodal myocytes of rabbits. Am. J. Physiol. 276: H1064-1077.
    • (1999) Am. J. Physiol , vol.276
    • VERHEIJCK, E.E.1
  • 107
    • 0028935894 scopus 로고
    • Effects of delayed rectifier current blockade by E-4031 on impulse generation in single sinoatrial nodal myocytes of the rabbit
    • VERHEIJCK, E.E. et al. 1995. Effects of delayed rectifier current blockade by E-4031 on impulse generation in single sinoatrial nodal myocytes of the rabbit. Circ. Res. 76: 607-615.
    • (1995) Circ. Res , vol.76 , pp. 607-615
    • VERHEIJCK, E.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.