Development of IL-17-mediated delayed-type hypersensitivity is not affected by down-regulation of IL-25 expression

Allergology International

Volumn 59, Issue 4, 2010, Pages 399-408

  Ishii, Akina ^a   Oboki, Keisuke ^a   Nambu, Aya ^b   Morita, Hideaki ^a,c   Ohno, Tatsukuni ^a   Kajiwara, Naoki ^a,b   Arae, Ken ^a,d   Sudo, Hajime ^b   Okumura, Ko ^b   Saito, Hirohisa ^a,b   Nakae, Susumu ^a,b,e  

^a National Research Institutefor Child Health and Development

^b JUNTENDO UNIVERSITY   (Japan)

^c KEIO UNIVERSITY   (Japan)

^d KYORIN UNIVERSITY   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

Author keywords

Allergy; Delayed type hypersensitivity; Helper t cell; Interleukin 17 family

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 25;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; DOWN REGULATION; EDEMA; HISTOPATHOLOGY; IMMUNE RESPONSE; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE;

EID: 78650832383     PISSN: 13238930     EISSN: 14401592     Source Type: Journal    
DOI: 10.2332/allergolint.10-OA-0218     Document Type: Article

References (32)

1. Grabbe S, Schwarz T. Immunoregulatory mechanisms involved in elicitation of allergic contact hypersensitivity. Immunol Today 1998;19:37-44
2. Bouley DM, Kanangat S, Wire W, Rouse BT. Characterization of herpes simplex virus type-1 infection and herpetic stromal keratitis development in IFN-γ knockout mice. J Immunol 1995;155:3964-71
3. Molesworth-Kenyon SJ, Oakes JE, Lausch RN. A novel role for neutrophils as a source of T cell-recruiting chemokines IP-10 and Mig during the DTH response to HSV-1 antigen. J Leukoc Biol 2005;77:552-9
4. Cooper AM, Dalton DK, Stewart TA, Griffin JP, Russell DG, Orme IM. Disseminated tuberculosis in interferon-γ gene-disrupted mice. J ExpMed 1993;178:2243-7
5. Akahira-Azuma M, Szczepanik M, Tsuji RF et al. Early delayed-type hypersensitivity eosinophil infiltrates depend on T helper 2 cytokines and interferon-γ via CXCR3 chemokines. Immunology 2004;111:306-17
6. Gao D, Kasten-Jolly J, Lawrence DA. The paradoxical effects of lead in interferon-γ knockout BALB_c mice. Toxicol Sci 2006;89:444-53
7. Feuerer M, Eulenburg K, Loddenkemper C, Hamann A, Huehn J. Self-limitation of Th1-mediated inflammation by IFN-γ. J Immunol 2006;176:2857-63
8. Irmler IM, Gajda M, Brauer R. Exacerbation of antigeninduced arthritis in IFN-γ-deficient mice as a result of unrestricted IL-17 response. J Immunol 2007;179:6228-36
9. Nakae S, Komiyama Y, Nambu A et al Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity 2002;17:375-87
10. Umemura M, Yahagi A, Hamada S et al. IL-17-mediated regulation of innate and acquired immune response against pulmonary Mycobacterium bovis bacille Calmette-Guerin infection. J Immunol 2007;178:3786-96
11. Angkasekwinai P, Park H, Wang YH et al. Interleukin 25 promotes the initiation of proallergic type 2 responses. J Exp Med 2007;204:1509-17
12. Fort MM, Cheung J, Yen D et al. IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo. Immunity 2001;15:985-95
13. Owyang AM, Zaph C, Wilson EH et al Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract. J Exp Med 2006;203:843-9
14. Fallon PG, Ballantyne SJ, Mangan NE et al. Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion. J ExpMed 2006;203:1105-16
15. Tamachi T, Maezawa Y, Ikeda K et al. IL-25 enhances allergic airway inflammation by amplifying a TH2 celldependent pathway in mice. J Allergy Clin Immunol 2006; 118:606-14
16. Ballantyne SJ, Barlow JL, Jolin HE et al. Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma. J Allergy Clin Immunol 2007;120:1324-31
17. Kleinschek MA, Owyang AM, Joyce-Shaikh B et al. IL-25 regulates Th17 function in autoimmune inflammation. J Exp Med 2007;204:161-70
18. Nambu A, Nakae S, Iwakura Y. IL-1β, but not IL-1α, is required for antigen-specific T cell activation and the induction of local inflammation in the delayed-type hypersensitivity responses. Int Immunol 2006;18:701-12
19. Ishigame H, Kakuta S, Nagai T et al. Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity 2009;30:108-19
20. Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B. TGF-β in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 2006;24:179-89
21. Nurieva R, Yang XO, Martinez G et al. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 2007;448:480-3
22. Korn T, Bettelli E, Gao W et al. IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells. Nature 2007;448:484-7
23. Zhou L, Ivanov II, Spolski R et al. IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol 2007;8:967-74.
24. Vogelzang A, McGuire HM, Yu D, Sprent J, Mackay CR, King C. A fundamental role for interleukin-21 in the generation of T follicular helper cells. Immunity 2008;29:127-37.
25. Nurieva RI, Chung Y, Hwang D et al Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity 2008;29:138-49
26. Frohlich A, Marsland BJ, Sonderegger I et al. IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo. Blood 2007;109:2023-31
27. Saenz SA, Taylor BC, Artis D. Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites. Immunol Rev 2008;226:172-90
28. Ikeda K, Nakajima H, Suzuki K et al. Mast cells produce interleukin-25 upon FcεRI-mediated activation. Blood 2003;101:3594-6
29. Kang CM, Jang AS, Ahn MH et al. Interleukin-25 and interleukin-13 production by alveolar macrophages in response to particles. Am J Respir Cell Mol Biol 2005;33: 290-6
30. Wang YH, Angkasekwinai P, Lu N et al. IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells. J Exp Med 2007;204:1837-47
31. Dolgachev V, Petersen BC, Budelsky AL, Berlin AA, Lukacs NW. Pulmonary IL-17E (IL-25) production and IL- 17RB+ myeloid cell-derived Th2 cytokine production are dependent upon stem cell factor-induced responses during chronic allergic pulmonary disease. J Immunol 2009; 183:5705-15
32. Harrington LE, Hatton RD, Mangan PR et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005;6:1123-32.