-
1
-
-
0036883940
-
Pancreatic cancer biology and genetics
-
Bardeesy N and DePinho RA: Pancreatic cancer biology and genetics. Nat Rev Cancer 2: 897-909, 2002.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 897-909
-
-
Bardeesy, N.1
DePinho, R.A.2
-
2
-
-
12144288807
-
Pancreatic cancer registry in Japan: 20 Years of experience
-
Matsuno S, Egawa S, Fukuyama S, et al: Pancreatic cancer registry in Japan: 20 years of experience. Pancreas 28: 219-230, 2004.
-
(2004)
Pancreas
, vol.28
, pp. 219-230
-
-
Matsuno, S.1
Egawa, S.2
Fukuyama, S.3
-
3
-
-
0002426462
-
Ductal adenocarcinoma of the pancreas
-
3rd edition. Hamilton SR and Aaltonen LA (eds). International Agency for Research on Cancer, Lyon
-
Klöppel G, Adler G, Hruban RH, Kern SE, Longnecker DS and Partanen TJ: Ductal adenocarcinoma of the pancreas. In: Tumours of the Digestive System. Vol 2. 3rd edition. Hamilton SR and Aaltonen LA (eds). International Agency for Research on Cancer, Lyon, pp221-230, 2000.
-
(2000)
Tumours of the Digestive System
, vol.2
, pp. 221-230
-
-
Klöppel, G.1
Adler, G.2
Hruban, R.H.3
Kern, S.E.4
Longnecker, D.S.5
Partanen, T.J.6
-
5
-
-
58149203295
-
Molecular targeting therapy for pancreatic cancer: Current knowledge and perspectives from bench to bedside
-
Furukawa T: Molecular targeting therapy for pancreatic cancer: current knowledge and perspectives from bench to bedside. J Gastroenterol 43: 905-911, 2008.
-
(2008)
J Gastroenterol
, vol.43
, pp. 905-911
-
-
Furukawa, T.1
-
7
-
-
0032822672
-
FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4
-
Xie M, Holcomb I, Deuel B, et al: FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4. Cytokine 11: 729-735, 1999.
-
(1999)
Cytokine
, vol.11
, pp. 729-735
-
-
Xie, M.1
Holcomb, I.2
Deuel, B.3
-
8
-
-
15844368097
-
Receptor specificity of the fibroblast growth factor family
-
Ornitz D, Xu J, Colvin J, et al: Receptor specificity of the fibroblast growth factor family. J Biol Chem 271: 15292-15297, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 15292-15297
-
-
Ornitz, D.1
Xu, J.2
Colvin, J.3
-
9
-
-
56949101730
-
Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention
-
Ho H, Pok S, Streit S, et al: Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention. J Hepatol 50: 118-127, 2009.
-
(2009)
J Hepatol
, vol.50
, pp. 118-127
-
-
Ho, H.1
Pok, S.2
Streit, S.3
-
10
-
-
63449138706
-
Resistance to chemotherapy is associated with fibroblast growth factor receptor 4 up-regulation
-
Roidl A, Berger H, Kumar S, Bange J, Knyazev P and Ullrich A: Resistance to chemotherapy is associated with fibroblast growth factor receptor 4 up-regulation. Clin Cancer Res 15: 2058-2066, 2009.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2058-2066
-
-
Roidl, A.1
Berger, H.2
Kumar, S.3
Bange, J.4
Knyazev, P.5
Ullrich, A.6
-
11
-
-
0033590984
-
Identification of receptor genes in renal cell carcinoma associated with angiogenesis by differential hybridization technique
-
Takahashi A, Sasaki H, Kim S, et al: Identification of receptor genes in renal cell carcinoma associated with angiogenesis by differential hybridization technique. Biochem Biophys Res Commun 257: 855-859, 1999.
-
(1999)
Biochem Biophys Res Commun
, vol.257
, pp. 855-859
-
-
Takahashi, A.1
Sasaki, H.2
Kim, S.3
-
12
-
-
33745099963
-
FGFR4 Arg388 allele correlates with tumour thickness and FGFR4 protein expression with survival of melanoma patients
-
Streit S, Mestel D, Schmidt M, Ullrich A and Berking C: FGFR4 Arg388 allele correlates with tumour thickness and FGFR4 protein expression with survival of melanoma patients. Br J Cancer 94: 1879-1886, 2006.
-
(2006)
Br J Cancer
, vol.94
, pp. 1879-1886
-
-
Streit, S.1
Mestel, D.2
Schmidt, M.3
Ullrich, A.4
Berking, C.5
-
13
-
-
65749086156
-
Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis
-
Huang X, Yang C, Jin C, Luo Y, Wang F and McKeehan W: Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis. Mol Carcinog 48: 553-562, 2009.
-
(2009)
Mol Carcinog
, vol.48
, pp. 553-562
-
-
Huang, X.1
Yang, C.2
Jin, C.3
Luo, Y.4
Wang, F.5
McKeehan, W.6
-
14
-
-
2542470676
-
Modulation of metabolic syndrome by fibroblast growth factor 19 (FGF19)?
-
Strack A and Myers R: Modulation of metabolic syndrome by fibroblast growth factor 19 (FGF19)? Endocrinology 145: 2591-2593, 2004.
-
(2004)
Endocrinology
, vol.145
, pp. 2591-2593
-
-
Strack, A.1
Myers, R.2
-
15
-
-
58949097425
-
Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression
-
Song K, Li T, Owsley E, Strom S and Chiang J: Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression. Hepatology 49: 297-305, 2009.
-
(2009)
Hepatology
, vol.49
, pp. 297-305
-
-
Song, K.1
Li, T.2
Owsley, E.3
Strom, S.4
Chiang, J.5
-
16
-
-
34247565954
-
Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members
-
Goetz R, Beenken A, Ibrahimi O, et al: Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members. Mol Cell Biol 27: 3417-3428, 2007.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 3417-3428
-
-
Goetz, R.1
Beenken, A.2
Ibrahimi, O.3
-
17
-
-
70149120326
-
Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice
-
Wu X, Ge H, Lemon B, et al: Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice. Proc Natl Acad Sci USA 106: 14379-14384, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 14379-14384
-
-
Wu, X.1
Ge, H.2
Lemon, B.3
-
18
-
-
48549092215
-
Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling
-
Pai R, Dunlap D, Qing J, Mohtashemi I, Hotzel K and French D: Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling. Cancer Res 68: 5086-5095, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 5086-5095
-
-
Pai, R.1
Dunlap, D.2
Qing, J.3
Mohtashemi, I.4
Hotzel, K.5
French, D.6
-
19
-
-
37849029159
-
Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models
-
Desnoyers L, Pai R, Ferrando R, et al: Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models. Oncogene 27: 85-97, 2008.
-
(2008)
Oncogene
, vol.27
, pp. 85-97
-
-
Desnoyers, L.1
Pai, R.2
Ferrando, R.3
-
20
-
-
33751073938
-
Cross-talk of WNT and FGF signaling pathways at GSK3beta to regulate beta-catenin and SNAIL signaling cascades
-
Katoh M: Cross-talk of WNT and FGF signaling pathways at GSK3beta to regulate beta-catenin and SNAIL signaling cascades. Cancer Biol Ther 5: 1059-1064, 2006.
-
(2006)
Cancer Biol Ther
, vol.5
, pp. 1059-1064
-
-
Katoh, M.1
-
21
-
-
0031872092
-
Characterization of keratinocyte growth factor and receptor expression in human pancreatic cancer
-
Ishiwata T, Friess H, Büchler M, Lopez M and Korc M: Characterization of keratinocyte growth factor and receptor expression in human pancreatic cancer. Am J Pathol 153: 213-222, 1998. (Pubitemid 28317524)
-
(1998)
American Journal of Pathology
, vol.153
, Issue.1
, pp. 213-222
-
-
Ishiwata, T.1
Friess, H.2
Buchler, M.W.3
Lopez, M.E.4
Korc, M.5
-
22
-
-
0031844173
-
Role of fibroblast growth factors and their receptors in pancreatic cancer and chronic pancreatitis
-
Kornmann M, Beger HG and Korc M: Role of fibroblast growth factors and their receptors in pancreatic cancer and chronic pancreatitis. Pancreas 17: 169-175, 1998.
-
(1998)
Pancreas
, vol.17
, pp. 169-175
-
-
Kornmann, M.1
Beger, H.G.2
Korc, M.3
-
23
-
-
34447318647
-
Enhanced expression of keratinocyte growth factor and its receptor correlates with venous invasion in pancreatic cancer
-
Cho K, Ishiwata T, Uchida E, et al: Enhanced expression of keratinocyte growth factor and its receptor correlates with venous invasion in pancreatic cancer. Am J Pathol 170: 1964-1974, 2007.
-
(2007)
Am J Pathol
, vol.170
, pp. 1964-1974
-
-
Cho, K.1
Ishiwata, T.2
Uchida, E.3
-
24
-
-
0027960891
-
Expression and functional activity of fibroblast growth factors and their receptors in human pancreatic cancer
-
DOI 10.1002/ijc.2910590515
-
Leung H, Gullick W and Lemoine N: Expression and functional activity of fibroblast growth factors and their receptors in human pancreatic cancer. Int J Cancer 59: 667-675, 1994. (Pubitemid 24358591)
-
(1994)
International Journal of Cancer
, vol.59
, Issue.5
, pp. 667-675
-
-
Leung, H.Y.1
Gullick, W.J.2
Lemoine, N.R.3
-
25
-
-
0025778586
-
FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern
-
Partanen J, Mäkalä T, Eerola E, et al: FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern. EMBO J 10: 1347-1354, 1991.
-
(1991)
EMBO J
, vol.10
, pp. 1347-1354
-
-
Partanen, J.1
Mäkalä, T.2
Eerola, E.3
-
26
-
-
0031700905
-
FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung
-
Weinstein M, Xu X, Ohyama K and Deng C: FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung. Development 125: 3615-3623, 1998.
-
(1998)
Development
, vol.125
, pp. 3615-3623
-
-
Weinstein, M.1
Xu, X.2
Ohyama, K.3
Deng, C.4
-
27
-
-
0030834170
-
Differential expression of the fibroblast growth factor receptor (FGFR) multigene family in normal human adult tissues
-
Hughes S: Differential expression of the fibroblast growth factor receptor (FGFR) multigene family in normal human adult tissues. J Histochem Cytochem 45: 1005-1019, 1997.
-
(1997)
J Histochem Cytochem
, vol.45
, pp. 1005-1019
-
-
Hughes, S.1
-
28
-
-
0036468871
-
Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele
-
Bange J, Prechtl D, Cheburkin Y, et al: Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele. Cancer Res 62: 840-847, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 840-847
-
-
Bange, J.1
Prechtl, D.2
Cheburkin, Y.3
-
29
-
-
4644223140
-
The fibroblast growth factor receptor-4 Arg388 allele is associated with prostate cancer initiation and progression
-
Wang J, Stockton D and Ittmann M: The fibroblast growth factor receptor-4 Arg388 allele is associated with prostate cancer initiation and progression. Clin Cancer Res 10: 6169-6178, 2004.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6169-6178
-
-
Wang, J.1
Stockton, D.2
Ittmann, M.3
-
30
-
-
33845922164
-
The fibroblast growth factor receptor 4 (FGFR4) Arg388 allele correlates with survival in head and neck squamous cell carcinoma
-
da Costa Andrade V, Parise H, Hors HP, de Melo Martins PC, Silva AP and Garicochea B: The fibroblast growth factor receptor 4 (FGFR4) Arg388 allele correlates with survival in head and neck squamous cell carcinoma. Exp Mol Pathol 82: 53-57, 2007.
-
(2007)
Exp Mol Pathol
, vol.82
, pp. 53-57
-
-
Da Costa Andrade, V.1
Parise, H.2
Hors, H.P.3
De Melo Martins, P.C.4
Silva, A.P.5
Garicochea, B.6
-
31
-
-
34250325792
-
Further observations on the relationship between the FGFR4 Gly388Arg polymorphism and lung cancer prognosis
-
Matakidou A, El Galta R, Rudd M, et al: Further observations on the relationship between the FGFR4 Gly388Arg polymorphism and lung cancer prognosis. Br J Cancer 96: 1904-1907, 2007.
-
(2007)
Br J Cancer
, vol.96
, pp. 1904-1907
-
-
Matakidou, A.1
El Galta, R.2
Rudd, M.3
-
32
-
-
0037191924
-
FGFR4 overexpression in pancreatic cancer is mediated by an intronic enhancer activated by HNF1alpha
-
Shah R, Ibbitt J, Alitalo K and Hurst H: FGFR4 overexpression in pancreatic cancer is mediated by an intronic enhancer activated by HNF1alpha. Oncogene 21: 8251-8261, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 8251-8261
-
-
Shah, R.1
Ibbitt, J.2
Alitalo, K.3
Hurst, H.4
-
33
-
-
57749105436
-
C-terminal tail of FGF19 determines its specificity toward Klotho co-receptors
-
Wu X, Lemon B, Li X, et al: C-terminal tail of FGF19 determines its specificity toward Klotho co-receptors. J Biol Chem 283: 33304-33309, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 33304-33309
-
-
Wu, X.1
Lemon, B.2
Li, X.3
-
34
-
-
0033783352
-
Fibroblast growth factors, their receptors and signaling
-
Powers C, McLeskey S and Wellstein A: Fibroblast growth factors, their receptors and signaling. Endocr Relat Cancer 7: 165-197, 2000.
-
(2000)
Endocr Relat Cancer
, vol.7
, pp. 165-197
-
-
Powers, C.1
McLeskey, S.2
Wellstein, A.3
-
35
-
-
33750525799
-
New approaches to blockade of alpha4-integrins, proven therapeutic targets in chronic inflammation
-
Kummer C and Ginsberg M: New approaches to blockade of alpha4-integrins, proven therapeutic targets in chronic inflammation. Biochem Pharmacol 72: 1460-1468, 2006.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 1460-1468
-
-
Kummer, C.1
Ginsberg, M.2
-
36
-
-
70350349130
-
Alterations in integrin expression modulates invasion of pancreatic cancer cells
-
Walsh N, Clynes M, Crown J and O'Donovan N: Alterations in integrin expression modulates invasion of pancreatic cancer cells. J Exp Clin Cancer Res 28: 140, 2009.
-
(2009)
J Exp Clin Cancer Res
, vol.28
, pp. 140
-
-
Walsh, N.1
Clynes, M.2
Crown, J.3
O'Donovan, N.4
-
37
-
-
34648852355
-
Pancreatic cancer-associated stroma production
-
Korc M: Pancreatic cancer-associated stroma production. Am J Surg 194: S84-S86, 2007.
-
(2007)
Am J Surg
, vol.194
-
-
Korc, M.1
-
38
-
-
0029062582
-
Fibroblast growth factor receptors display both common and distinct signaling pathways
-
Shaoul E, Reich-Slotky R, Berman B and Ron D: Fibroblast growth factor receptors display both common and distinct signaling pathways. Oncogene 10: 1553-1561, 1995.
-
(1995)
Oncogene
, vol.10
, pp. 1553-1561
-
-
Shaoul, E.1
Reich-Slotky, R.2
Berman, B.3
Ron, D.4
-
39
-
-
0033594971
-
Comparison of the intracellular signaling responses by three chimeric fibroblast growth factor receptors in PC12 cells
-
Raffioni S, Thomas D, Foehr E, Thompson L and Bradshaw R: Comparison of the intracellular signaling responses by three chimeric fibroblast growth factor receptors in PC12 cells. Proc Natl Acad Sci USA 96: 7178-7183, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7178-7183
-
-
Raffioni, S.1
Thomas, D.2
Foehr, E.3
Thompson, L.4
Bradshaw, R.5
|