-
1
-
-
18244407799
-
Steps toward mapping the human vasculature by phage display
-
Arap W, Kolonin MG, Trepel M, Lahdenranta J, Cardo-Vila M, Giordano RJ, Mintz PJ, Ardelt PU, Yao VJ, Vidal CI, et al. 2002. Steps toward mapping the human vasculature by phage display. Nat Med. 8:121-127.
-
(2002)
Nat Med
, vol.8
, pp. 121-127
-
-
Arap, W.1
Kolonin, M.G.2
Trepel, M.3
Lahdenranta, J.4
Cardo-Vila, M.5
Giordano, R.J.6
Mintz, P.J.7
Ardelt, P.U.8
Yao, V.J.9
Vidal, C.I.10
-
2
-
-
0032535999
-
Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
-
Arap W, Pasqualini R, Ruoslahti E. 1998a. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science. 279:377-380.
-
(1998)
Science
, vol.279
, pp. 377-380
-
-
Arap, W.1
Pasqualini, R.2
Ruoslahti, E.3
-
4
-
-
0025019614
-
Metalloprotease activity of CD13/ aminopeptidase N on the surface of human myeloid cells
-
Ashmun RA, Look AT. 1990. Metalloprotease activity of CD13/ aminopeptidase N on the surface of human myeloid cells. Blood. 75:462-469.
-
(1990)
Blood
, vol.75
, pp. 462-469
-
-
Ashmun, R.A.1
Look, A.T.2
-
5
-
-
0026696167
-
Deletion of the zincbinding motif of CD13/aminopeptidase N molecules results in loss of epitopes that mediate binding of inhibitory antibodies
-
Ashmun R, Shapiro LH, Look AT. 1992. Deletion of the zincbinding motif of CD13/aminopeptidase N molecules results in loss of epitopes that mediate binding of inhibitory antibodies. Blood. 79:3344-3349.
-
(1992)
Blood
, vol.79
, pp. 3344-3349
-
-
Ashmun, R.1
Shapiro, L.H.2
Look, A.T.3
-
7
-
-
0842308319
-
Transmembrane proteases in cell growth and invasion: New contributors to angiogenesis?
-
Bauvois B. 2004. Transmembrane proteases in cell growth and invasion: new contributors to angiogenesis? Oncongene. 23:317-329.
-
(2004)
Oncongene
, vol.23
, pp. 317-329
-
-
Bauvois, B.1
-
8
-
-
33644875741
-
Aminopeptidase-N/CD13 (EC 3.4.11.2) inhibitors: Chemistry, biological evaluations, and therapeutic prospects
-
Bauvois B, Dauzonne D. 2006. Aminopeptidase-N/CD13 (EC 3.4.11.2) inhibitors: chemistry, biological evaluations, and therapeutic prospects. Med Res Rev. 26:88-130.
-
(2006)
Med Res Rev
, vol.26
, pp. 88-130
-
-
Bauvois, B.1
Dauzonne, D.2
-
9
-
-
0035254206
-
CD13/APN is activated by angiogenic signals and is essential for capillary tube formation
-
Bhagwat SV, Lahdenranta J, Giordano R, Arap W, Pasqualini R, Shapiro LH. 2001. CD13/APN is activated by angiogenic signals and is essential for capillary tube formation. Blood. 97:652-659.
-
(2001)
Blood
, vol.97
, pp. 652-659
-
-
Bhagwat, S.V.1
Lahdenranta, J.2
Giordano, R.3
Arap, W.4
Pasqualini, R.5
Shapiro, L.H.6
-
10
-
-
0037372507
-
The angiogenic regulator CD13/APN is a transcriptional target of Ras signaling pathways in endothelial morphogenesis
-
Bhagwat SV, Petrovic N, Okamoto Y, Shapiro LH. 2003. The angiogenic regulator CD13/APN is a transcriptional target of Ras signaling pathways in endothelial morphogenesis. Blood. 101:1818-1826.
-
(2003)
Blood
, vol.101
, pp. 1818-1826
-
-
Bhagwat, S.V.1
Petrovic, N.2
Okamoto, Y.3
Shapiro, L.H.4
-
11
-
-
0030782738
-
Expression and localization of aminopeptidase A, aminopeptidase N, and dipeptidyl peptidase IV in benign and malignant human prostate tissue
-
Bogenrieder T, Finstad CL, Freeman RH, Papandreou CN, Scher HI, Albino AP, Reuter VE, Nanus DM. 1997. Expression and localization of aminopeptidase A, aminopeptidase N, and dipeptidyl peptidase IV in benign and malignant human prostate tissue. Prostate. 33:225-232.
-
(1997)
Prostate
, vol.33
, pp. 225-232
-
-
Bogenrieder, T.1
Finstad, C.L.2
Freeman, R.H.3
Papandreou, C.N.4
Scher, H.I.5
Albino, A.P.6
Reuter, V.E.7
Nanus, D.M.8
-
12
-
-
0030587165
-
p161, a murine membrane protein expressed on mast cells and some macrophages, is mouse CD13/aminopeptidase N
-
Chen H, Kinzer CA, Paul WE. 1996. p161, a murine membrane protein expressed on mast cells and some macrophages, is mouse CD13/aminopeptidase N. J Immunol. 157:2593-2600.
-
(1996)
J Immunol
, vol.157
, pp. 2593-2600
-
-
Chen, H.1
Kinzer, C.A.2
Paul, W.E.3
-
13
-
-
2342429229
-
Strategies for improving the anti-neoplastic activity of TNF by tumor targeting
-
Corti A. 2004. Strategies for improving the anti-neoplastic activity of TNF by tumor targeting. Methods Mol Med. 98:247-264.
-
(2004)
Methods Mol Med
, vol.98
, pp. 247-264
-
-
Corti, A.1
-
14
-
-
14944353793
-
Tumor vascular targeting with tumor necrosis factor alpha and chemotherapeutic drugs
-
Corti A, Ponzoni M. 2004. Tumor vascular targeting with tumor necrosis factor alpha and chemotherapeutic drugs. Ann N Y Acad Sci. 1028:104-112.
-
(2004)
Ann N Y Acad Sci
, vol.1028
, pp. 104-112
-
-
Corti, A.1
Ponzoni, M.2
-
15
-
-
0036468937
-
Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells
-
Curnis F, Arrigoni G, Sacchi A, Fischetti L, Arap W, Pasqualini R, Corti A. 2002. Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells. Cancer Res. 62:867-874.
-
(2002)
Cancer Res
, vol.62
, pp. 867-874
-
-
Curnis, F.1
Arrigoni, G.2
Sacchi, A.3
Fischetti, L.4
Arap, W.5
Pasqualini, R.6
Corti, A.7
-
16
-
-
16844363607
-
Targeted delivery of IFNgamma to tumor vessels uncouples antitumor from counterregulatory mechanisms
-
Curnis F, Gasparri A, Sacchi A, Cattaneo A, Magni F, Corti A. 2005. Targeted delivery of IFNgamma to tumor vessels uncouples antitumor from counterregulatory mechanisms. Cancer Res. 65:2906-2913.
-
(2005)
Cancer Res
, vol.65
, pp. 2906-2913
-
-
Curnis, F.1
Gasparri, A.2
Sacchi, A.3
Cattaneo, A.4
Magni, F.5
Corti, A.6
-
17
-
-
0033764170
-
Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13)
-
Curnis F, Sacchi A, Borgna L, Magni F, Gasparri A, Corti A. 2000. Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13). Nat Biotechnol. 18:1185-1190.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 1185-1190
-
-
Curnis, F.1
Sacchi, A.2
Borgna, L.3
Magni, F.4
Gasparri, A.5
Corti, A.6
-
18
-
-
0036678474
-
Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration
-
Curnis F, Sacchi A, Corti A. 2002. Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration. J Clin Invest. 110:475-482.
-
(2002)
J Clin Invest
, vol.110
, pp. 475-482
-
-
Curnis, F.1
Sacchi, A.2
Corti, A.3
-
19
-
-
0028053036
-
Expression of aminopeptidase-n (CD 13) in normal tissues and malignant neoplasms of epithelial and lymphoid origin
-
Dixon J, Kaklamanis L, Turley H, Hickson ID, Leek RD, Harris AL, Gatter KC. 1994. Expression of aminopeptidase-n (CD 13) in normal tissues and malignant neoplasms of epithelial and lymphoid origin. J Clin Pathol. 47:43-47.
-
(1994)
J Clin Pathol
, vol.47
, pp. 43-47
-
-
Dixon, J.1
Kaklamanis, L.2
Turley, H.3
Hickson, I.D.4
Leek, R.D.5
Harris, A.L.6
Gatter, K.C.7
-
20
-
-
0023585057
-
Classification of acute myeloid leukemias- A comparison of FAB and immunophenotyping
-
Drexler HG. 1987. Classification of acute myeloid leukemias- a comparison of FAB and immunophenotyping. Leukemia. 1:697-705.
-
(1987)
Leukemia
, vol.1
, pp. 697-705
-
-
Drexler, H.G.1
-
21
-
-
0032819838
-
Anti-cancer activity of targeted pro-apoptotic peptides
-
Ellerby HM, Arap W, Ellerby LM, Kain R, Andrusiak R, Rio GD, Krajewski S, Lombardo CR, Rao R, Ruoslahti E, et al. 1999. Anti-cancer activity of targeted pro-apoptotic peptides. Nat Med. 5:1032-1038.
-
(1999)
Nat Med
, vol.5
, pp. 1032-1038
-
-
Ellerby, H.M.1
Arap, W.2
Ellerby, L.M.3
Kain, R.4
Andrusiak, R.5
Rio, G.D.6
Krajewski, S.7
Lombardo, C.R.8
Rao, R.9
Ruoslahti, E.10
-
22
-
-
12444302211
-
Cell biology and pathology of liver sinusoidal endothelial cells
-
Enomoto K, Nishikawa Y, Omori Y, Tokairin T, Yoshida M, Ohi N, Nishimura T, Yamamoto Y, Li Q. 2004. Cell biology and pathology of liver sinusoidal endothelial cells. Med Electron Microsc. 37:208-215.
-
(2004)
Med Electron Microsc
, vol.37
, pp. 208-215
-
-
Enomoto, K.1
Nishikawa, Y.2
Omori, Y.3
Tokairin, T.4
Yoshida, M.5
Ohi, N.6
Nishimura, T.7
Yamamoto, Y.8
Li, Q.9
-
23
-
-
33749449024
-
Aminopeptidase N (APN/CD13) is selectively expressed in vascular endothelial cells and plays multiple roles in angiogenesis
-
Fukasawa K, Fujii H, Saitoh Y, Koizumi K, Aozuka Y, Sekine K, Yamada M, Saiki I, Nishikawa K. 2006. Aminopeptidase N (APN/CD13) is selectively expressed in vascular endothelial cells and plays multiple roles in angiogenesis. Cancer Lett. 243:135-143.
-
(2006)
Cancer Lett
, vol.243
, pp. 135-143
-
-
Fukasawa, K.1
Fujii, H.2
Saitoh, Y.3
Koizumi, K.4
Aozuka, Y.5
Sekine, K.6
Yamada, M.7
Saiki, I.8
Nishikawa, K.9
-
24
-
-
34748846833
-
Binding and internalization of NGRpeptide-targeted liposomal doxorubicin (TVT-DOX) in CD13-expressing cells and its antitumor effects
-
Garde SV, Forté AJ, Ge M, Lepekhin EA, Panchal CJ, Rabbani SA, Wu JJ. 2007. Binding and internalization of NGRpeptide-targeted liposomal doxorubicin (TVT-DOX) in CD13-expressing cells and its antitumor effects. Anticancer Drugs. 18:1189-1200.
-
(2007)
Anticancer Drugs
, vol.18
, pp. 1189-1200
-
-
Garde, S.V.1
Forté, A.J.2
Ge, M.3
Lepekhin, E.A.4
Panchal, C.J.5
Rabbani, S.A.6
Wu, J.J.7
-
25
-
-
71049169690
-
Defining the optimal biological dose of NGR-hTNF, a selective vascular targeting agent, in advanced solid tumours
-
Gregorc V, Citterio G, Vitali G, Spreafico A, Scifo P, Borri A, Donadoni G, Rossoni G, Corti A, Caligaris-Cappio F, et al. 2010. Defining the optimal biological dose of NGR-hTNF, a selective vascular targeting agent, in advanced solid tumours. Eur J Cancer. 46:198-206.
-
(2010)
Eur J Cancer
, vol.46
, pp. 198-206
-
-
Gregorc, V.1
Citterio, G.2
Vitali, G.3
Spreafico, A.4
Scifo, P.5
Borri, A.6
Donadoni, G.7
Rossoni, G.8
Corti, A.9
Caligaris-Cappio, F.10
-
26
-
-
67650638995
-
Phase Ib study of NGR-hTNF, a selective vascular targeting agent, administered at low doses in combination with doxorubicin to patients with advanced solid tumours
-
Gregorc V, Santoro A, Bennicelli E, Punt CJ, Citterio G, Timmer- Bonte JN, Caligaris Cappio F, Lambiase A, Bordignon C, van Herpen CM. 2009. Phase Ib study of NGR-hTNF, a selective vascular targeting agent, administered at low doses in combination with doxorubicin to patients with advanced solid tumours. Br J Cancer. 101:219-224.
-
(2009)
Br J Cancer
, vol.101
, pp. 219-224
-
-
Gregorc, V.1
Santoro, A.2
Bennicelli, E.3
Punt, C.J.4
Citterio, G.5
Timmer- Bonte, J.N.6
Caligaris Cappio, F.7
Lambiase, A.8
Bordignon, C.9
Van Herpen, C.M.10
-
27
-
-
77956414169
-
Phase II study of asparagine-glycine-argininehuman tumor necrosis factor {alpha}, a selective vascular targeting agent, in previously treated patients with malignant pleural mesothelioma
-
Gregorc V, Zucali PA, Santoro A, Ceresoli GL, Citterio G, De Pas TM, Zilembo N, De Vincenzo F, Simonelli M, Rossoni G, et al. 2010. Phase II study of asparagine-glycine-argininehuman tumor necrosis factor {alpha}, a selective vascular targeting agent, in previously treated patients with malignant pleural mesothelioma. J Clin Oncol. 28:2604-2611.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2604-2611
-
-
Gregorc, V.1
Zucali, P.A.2
Santoro, A.3
Ceresoli, G.L.4
Citterio, G.5
De Pas, T.M.6
Zilembo, N.7
De Vincenzo, F.8
Simonelli, M.9
Rossoni, G.10
-
28
-
-
0034963928
-
Incorporation of tumor-targeting peptides into recombinant adeno-associated virus capsids
-
Grifman M, Trepel M, Speece P, Gilbert LB, Arap W, Pasqualini R, Weitzman MD. 2001. Incorporation of tumor-targeting peptides into recombinant adeno-associated virus capsids. Mol Ther. 3:964-975.
-
(2001)
Mol Ther
, vol.3
, pp. 964-975
-
-
Grifman, M.1
Trepel, M.2
Speece, P.3
Gilbert, L.B.4
Arap, W.5
Pasqualini, R.6
Weitzman, M.D.7
-
29
-
-
0036161112
-
Aminopeptidase N is involved in cell motility and angiogenesis: Its clinical significance in human colon cancer
-
Hashida H, Takabayashi A, Kanai M, Adachi M, Kondo K, Kohno N, Yamaoka Y, Miyake M. 2002. Aminopeptidase N is involved in cell motility and angiogenesis: its clinical significance in human colon cancer. Gastroenterology. 122:376-386.
-
(2002)
Gastroenterology
, vol.122
, pp. 376-386
-
-
Hashida, H.1
Takabayashi, A.2
Kanai, M.3
Adachi, M.4
Kondo, K.5
Kohno, N.6
Yamaoka, Y.7
Miyake, M.8
-
30
-
-
33646587699
-
Immunohistochemical expression of aminopeptidase N (CD13) in human lung squamous cell carcinomas, with special reference to Bestatin adjuvant therapy
-
Ichimura E, Yamada M, Nishikawa K, Abe F, Nakajima T. 2006. Immunohistochemical expression of aminopeptidase N (CD13) in human lung squamous cell carcinomas, with special reference to Bestatin adjuvant therapy. Pathol Int. 56:296-300.
-
(2006)
Pathol Int
, vol.56
, pp. 296-300
-
-
Ichimura, E.1
Yamada, M.2
Nishikawa, K.3
Abe, F.4
Nakajima, T.5
-
31
-
-
0037389803
-
Clinical significance of aminopeptidase N/CD13 expression in human pancreatic carcinoma
-
Ikeda N, Nakajima Y, Tokuhara T, Hattori N, Sho M, Kanehiro H, Miyake M. 2003. Clinical significance of aminopeptidase N/CD13 expression in human pancreatic carcinoma. Clin Cancer Res. 9:1503-1508.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1503-1508
-
-
Ikeda, N.1
Nakajima, Y.2
Tokuhara, T.3
Hattori, N.4
Sho, M.5
Kanehiro, H.6
Miyake, M.7
-
32
-
-
73349117829
-
Stromal aminopeptidase N expression: Correlation with angiogenesis in non-small-cell lung cancer
-
Ito S, Miyahara R, Takahashi R, Nagai S, Takenaka K, Wada H, Tanaka F. 2009. Stromal aminopeptidase N expression: correlation with angiogenesis in non-small-cell lung cancer. Gen Thorac Cardiovasc Surg. 57:591-598.
-
(2009)
Gen Thorac Cardiovasc Surg
, vol.57
, pp. 591-598
-
-
Ito, S.1
Miyahara, R.2
Takahashi, R.3
Nagai, S.4
Takenaka, K.5
Wada, H.6
Tanaka, F.7
-
33
-
-
34047143135
-
Clinicopathological significance of aminopeptidase N/CD13 expression in human gastric carcinoma
-
Kawamura J, Shimada Y, Kitaichi H, Komoto I, Hashimoto Y, Kaganoi J, Miyake M, Yamasaki S, Kondo K, Imamura M. 2007. Clinicopathological significance of aminopeptidase N/CD13 expression in human gastric carcinoma. Hepatogastroenterology. 54:36-40. (Pubitemid 46511642)
-
(2007)
Hepato-Gastroenterology
, vol.54
, Issue.73
, pp. 36-40
-
-
Kawamura, J.1
Shimada, Y.2
Kitaichi, H.3
Komoto, I.4
Hashimoto, Y.5
Kaganoi, J.6
Miyake, M.7
Yamasaki, S.8
Kondo, K.9
Imamura, M.10
-
34
-
-
0028322161
-
The 140-kDa protein of blood-brain barrier-associated pericytes is identical to aminopeptidase N
-
Kunz J, Krause D, Kremer M, Dermietzel R. 1994. The 140-kDa protein of blood-brain barrier-associated pericytes is identical to aminopeptidase N. J Neurochem. 62:2375-2386.
-
(1994)
J Neurochem
, vol.62
, pp. 2375-2386
-
-
Kunz, J.1
Krause, D.2
Kremer, M.3
Dermietzel, R.4
-
35
-
-
33947414087
-
Sinusoidal remodeling and angiogenesis: A new function for the liver-specific pericyte?
-
Lee JS, Semela D, Iredale J, Shah VH. 2007. Sinusoidal remodeling and angiogenesis: a new function for the liver-specific pericyte? Hepatology. 45:817-825.
-
(2007)
Hepatology
, vol.45
, pp. 817-825
-
-
Lee, J.S.1
Semela, D.2
Iredale, J.3
Shah, V.H.4
-
36
-
-
0034068116
-
Incorporation of tumor vasculature targeting motifs into moloney murine leukemia virus env escort proteins enhances retrovirus binding and transduction of human endothelial cells
-
Liu L, Anderson WF, Beart RW, Gordon EM, Hall FL. 2000. Incorporation of tumor vasculature targeting motifs into moloney murine leukemia virus env escort proteins enhances retrovirus binding and transduction of human endothelial cells. J Virol. 74:5320-5328.
-
(2000)
J Virol
, vol.74
, pp. 5320-5328
-
-
Liu, L.1
Anderson, W.F.2
Beart, R.W.3
Gordon, E.M.4
Hall, F.L.5
-
37
-
-
0024518875
-
Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N
-
Look AT, Ashmun RA, Shapiro LH, Peiper SC. 1989. Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N. J Clin Invest. 83:1299-1307.
-
(1989)
J Clin Invest
, vol.83
, pp. 1299-1307
-
-
Look, A.T.1
Ashmun, R.A.2
Shapiro, L.H.3
Peiper, S.C.4
-
38
-
-
33947585099
-
The structure and main functions of aminopeptidase N
-
Luan Y, Wu W. 2007. The structure and main functions of aminopeptidase N. Curr Med Chem. 14:639-647.
-
(2007)
Curr Med Chem
, vol.14
, pp. 639-647
-
-
Luan, Y.1
Wu, W.2
-
39
-
-
34748827967
-
CD13/ APN transcription is regulated by the proto-oncogene c-Maf via an atypical response element
-
Mahoney KM, Petrovic N, Schacke W, Shapiro LH. 2007. CD13/ APN transcription is regulated by the proto-oncogene c-Maf via an atypical response element. Gene. 403:178-187.
-
(2007)
Gene
, vol.403
, pp. 178-187
-
-
Mahoney, K.M.1
Petrovic, N.2
Schacke, W.3
Shapiro, L.H.4
-
40
-
-
48149111676
-
The moonlighting enzyme CD13: Old and new functions to target
-
Mina-Osorio P. 2008. The moonlighting enzyme CD13: old and new functions to target. Trends Mol Med. 14:361-371.
-
(2008)
Trends Mol Med
, vol.14
, pp. 361-371
-
-
Mina-Osorio, P.1
-
41
-
-
0025764053
-
Variable O-glycosylation of CD13 (aminopeptidase N)
-
O'Connel P, Gerkis V, D'Apice AJ. 1991. Variable O-glycosylation of CD13 (aminopeptidase N). J Biol Chem. 266:4593-4597.
-
(1991)
J Biol Chem
, vol.266
, pp. 4593-4597
-
-
O'Connel, P.1
Gerkis, V.2
D'Apice, A.J.3
-
42
-
-
0021868687
-
Vascular, plasma membrane aminopeptidase M: Metabolism of vasoactive peptides
-
Palmieri FE, Petrelli JJ, Ward PE. 1985. Vascular, plasma membrane aminopeptidase M: metabolism of vasoactive peptides. Biochem Pharmacol. 34:2309-2317.
-
(1985)
Biochem Pharmacol
, vol.34
, pp. 2309-2317
-
-
Palmieri, F.E.1
Petrelli, J.J.2
Ward, P.E.3
-
43
-
-
0033950895
-
Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis
-
Pasqualini R, Koivunen E, Kain R, Lahdenranta J, Sakamoto M, Stryhn A, Ashmun RA, Shapiro LH, Arap W, Ruoslahti E. 2000. Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis. Cancer Res. 60:722-727.
-
(2000)
Cancer Res
, vol.60
, pp. 722-727
-
-
Pasqualini, R.1
Koivunen, E.2
Kain, R.3
Lahdenranta, J.4
Sakamoto, M.5
Stryhn, A.6
Ashmun, R.A.7
Shapiro, L.H.8
Arap, W.9
Ruoslahti, E.10
-
44
-
-
0029932458
-
Organ targeting in vivo using phage display peptide libraries
-
Pasqualini R, Ruoslahti E. 1996. Organ targeting in vivo using phage display peptide libraries. Nature. 380:364-366.
-
(1996)
Nature
, vol.380
, pp. 364-366
-
-
Pasqualini, R.1
Ruoslahti, E.2
-
45
-
-
10744233861
-
Vascular damage and anti-angiogenic effects of tumor vessel-targeted liposomal chemotherapy
-
Pastorino F, Brignole C, Marimpietri D, Cilli M, Gambini C, Ribatti D, Longhi R, Allen TM, Corti A, Ponzoni M. 2003. Vascular damage and anti-angiogenic effects of tumor vessel-targeted liposomal chemotherapy. Cancer Res. 63:7400-7409.
-
(2003)
Cancer Res
, vol.63
, pp. 7400-7409
-
-
Pastorino, F.1
Brignole, C.2
Marimpietri, D.3
Cilli, M.4
Gambini, C.5
Ribatti, D.6
Longhi, R.7
Allen, T.M.8
Corti, A.9
Ponzoni, M.10
-
46
-
-
0028965183
-
Aminopeptidase N: A constitutive cell-surface protein on human dermal fibroblasts
-
Piela-Smith TH, Korn JH. 1995. Aminopeptidase N: a constitutive cell-surface protein on human dermal fibroblasts. Cell Immunol. 162:42-48.
-
(1995)
Cell Immunol
, vol.162
, pp. 42-48
-
-
Piela-Smith, T.H.1
Korn, J.H.2
-
47
-
-
34248359535
-
Impaired angiogenesis in aminopeptidase N-null mice
-
Rangel R, Sun Y, Guzman-Rojas L, Ozawa MG, Sun J, Giordano RJ, Van Pelt CS, Tinkey PT, Behringer RR, Sidman RL, et al. 2007. Impaired angiogenesis in aminopeptidase N-null mice. Proc Natl Acad Sci U S A. 104:4588-4593.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 4588-4593
-
-
Rangel, R.1
Sun, Y.2
Guzman-Rojas, L.3
Ozawa, M.G.4
Sun, J.5
Giordano, R.J.6
Van Pelt, C.S.7
Tinkey, P.T.8
Behringer, R.R.9
Sidman, R.L.10
-
48
-
-
0026636749
-
Induction of CD13 expression on fresh myeloid leukaemia: Correlation of CD13 expression with aminopeptidase-N activity
-
Razak K, Newland AC. 1992a. Induction of CD13 expression on fresh myeloid leukaemia: correlation of CD13 expression with aminopeptidase-N activity. Leuk Res. 16:625-630.
-
(1992)
Leuk Res
, vol.16
, pp. 625-630
-
-
Razak, K.1
Newland, A.C.2
-
49
-
-
0027103632
-
The significance of aminopeptidases and haematopoietic cell differentiation
-
Razak K, Newland AC. 1992b. The significance of aminopeptidases and haematopoietic cell differentiation. Blood Rev. 6:243-250.
-
(1992)
Blood Rev
, vol.6
, pp. 243-250
-
-
Razak, K.1
Newland, A.C.2
-
50
-
-
0033082368
-
CD13 - Not just a marker in leukemia typing
-
Riemann D, Kehlen A, Langner J. 1999. CD13 - not just a marker in leukemia typing. Immunol Today. 20:83-88.
-
(1999)
Immunol Today
, vol.20
, pp. 83-88
-
-
Riemann, D.1
Kehlen, A.2
Langner, J.3
-
51
-
-
0031111916
-
Induction of aminopeptidase N/CD13 on human lymphocytes after adhesion to fibroblast-like synoviocytes, endothelial cells, epithelial cells, and monocytes/macrophages
-
Riemann D, Kehlen A, Thiele K, Lohn M, Langner J. 1997. Induction of aminopeptidase N/CD13 on human lymphocytes after adhesion to fibroblast-like synoviocytes, endothelial cells, epithelial cells, and monocytes/macrophages. J Immunol. 158:3425-3432.
-
(1997)
J Immunol
, vol.158
, pp. 3425-3432
-
-
Riemann, D.1
Kehlen, A.2
Thiele, K.3
Lohn, M.4
Langner, J.5
-
52
-
-
26244443837
-
Canalicular immunostaining of aminopeptidase N (CD13) as a diagnostic marker for hepatocellular carcinoma
-
Rocken C, Licht J, Roessner A, Carl-McGrath S. 2005. Canalicular immunostaining of aminopeptidase N (CD13) as a diagnostic marker for hepatocellular carcinoma. J Clin Pathol. 58:1069-1075.
-
(2005)
J Clin Pathol
, vol.58
, pp. 1069-1075
-
-
Rocken, C.1
Licht, J.2
Roessner, A.3
Carl-McGrath, S.4
-
53
-
-
77956438555
-
Activity and safety of NGR-hTNF, a selective vascular-targeting agent, in previously treated patients with advanced hepatocellular carcinoma
-
Santoro A, Pressiani T, Citterio G, Rossoni G, Donadoni G, Pozzi F, Rimassa L, Personeni N, Bozzarelli S, Rossoni G, et al. 2010. Activity and safety of NGR-hTNF, a selective vascular-targeting agent, in previously treated patients with advanced hepatocellular carcinoma. Br J Cancer. 103:837-844.
-
(2010)
Br J Cancer
, vol.103
, pp. 837-844
-
-
Santoro, A.1
Pressiani, T.2
Citterio, G.3
Rossoni, G.4
Donadoni, G.5
Pozzi, F.6
Rimassa, L.7
Personeni, N.8
Bozzarelli, S.9
Rossoni, G.10
-
54
-
-
77957197962
-
Phase II study of NGR-hTNF, a selective vascular targeting agent, in patients with metastatic colorectal cancer after failure of standard therapy
-
Santoro A, Rimassa L, Sobrero AF, Citterio G, Sclafani F, Carnaghi C, Pessino A, Caprioni F, Andretta V, Tronconi M, et al. 2010. Phase II study of NGR-hTNF, a selective vascular targeting agent, in patients with metastatic colorectal cancer after failure of standard therapy. Eur J Cancer. 46:2746-2752.
-
(2010)
Eur J Cancer
, vol.46
, pp. 2746-2752
-
-
Santoro, A.1
Rimassa, L.2
Sobrero, A.F.3
Citterio, G.4
Sclafani, F.5
Carnaghi, C.6
Pessino, A.7
Caprioni, F.8
Andretta, V.9
Tronconi, M.10
-
55
-
-
33749154707
-
Expression of aminopeptidase N/CD13 in human ovarian cancers
-
Surowiak P, Drag M, Materna V, Suchocki S, Grzywa R, Spaczynski M, Dietel M, Oleksyszyn J, Zabel M, Lage H. 2006. Expression of aminopeptidase N/CD13 in human ovarian cancers. Int J Gynecol Cancer. 16:1783-1788.
-
(2006)
Int J Gynecol Cancer
, vol.16
, pp. 1783-1788
-
-
Surowiak, P.1
Drag, M.2
Materna, V.3
Suchocki, S.4
Grzywa, R.5
Spaczynski, M.6
Dietel, M.7
Oleksyszyn, J.8
Zabel, M.9
Lage, H.10
-
56
-
-
0027479013
-
Aminopeptidases: Structure and function
-
Taylor A. 1993. Aminopeptidases: structure and function. FASEB J. 7:290-298.
-
(1993)
FASEB J
, vol.7
, pp. 290-298
-
-
Taylor, A.1
-
57
-
-
35148889105
-
Inhibition of APN/CD13 leads to suppressed progressive potentila in ovarian carcinoma cells
-
Terauchi M, Kajiyama H, Shibata K, Ino K, Nawa A, Mizutani S, Kikkawa F. 2007. Inhibition of APN/CD13 leads to suppressed progressive potentila in ovarian carcinoma cells. BMC Cancer. 7:140.
-
(2007)
BMC Cancer
, vol.7
, pp. 140
-
-
Terauchi, M.1
Kajiyama, H.2
Shibata, K.3
Ino, K.4
Nawa, A.5
Mizutani, S.6
Kikkawa, F.7
-
58
-
-
33746080895
-
Clinical significance of aminopeptidase N in non-small cell lung cancer
-
Tokuhara T, Hattori N, Ishida H, Hirai T, Higashiyama M, Kodama K, Miyake M. 2006. Clinical significance of aminopeptidase N in non-small cell lung cancer. Clin Cancer Res. 12:3971-3978.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3971-3978
-
-
Tokuhara, T.1
Hattori, N.2
Ishida, H.3
Hirai, T.4
Higashiyama, M.5
Kodama, K.6
Miyake, M.7
-
59
-
-
41949139764
-
Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer
-
Tsukamoto H, Shibata K, Kajiyama H, Terauchi M, Nawa A, Kikkawa F. 2008. Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer. BMC Cancer. 8:74.
-
(2008)
BMC Cancer
, vol.8
, pp. 74
-
-
Tsukamoto, H.1
Shibata, K.2
Kajiyama, H.3
Terauchi, M.4
Nawa, A.5
Kikkawa, F.6
-
60
-
-
76749096433
-
Phase I clinical and magnetic resonance imaging study of the vascular agent NGR-hTNF in patients with advanced cancers (European Organization for Research and Treatment of Cancer Study 16041)
-
van Laarhoven HW, Fiedler W, Desar IM, van Asten JJ, Marreaud S, Lacombe D, Govaerts AS, Bogaerts J, Lasch P, Timmer- Bonte JN, et al. 2010. Phase I clinical and magnetic resonance imaging study of the vascular agent NGR-hTNF in patients with advanced cancers (European Organization for Research and Treatment of Cancer Study 16041). Clin Cancer Res. 16:1315-1323.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1315-1323
-
-
Van Laarhoven, H.W.1
Fiedler, W.2
Desar, I.M.3
Van Asten, J.J.4
Marreaud, S.5
Lacombe, D.6
Govaerts, A.S.7
Bogaerts, J.8
Lasch, P.9
Timmer- Bonte, J.N.10
-
61
-
-
37549035458
-
Aminopeptidase N (APN)/CD13-dependent CXCR4 downregulation is associated with diminished cell migration, proliferation and invasion
-
Wulfaenger J, Niedling S, Riemann D, Seliger B. 2008. Aminopeptidase N (APN)/CD13-dependent CXCR4 downregulation is associated with diminished cell migration, proliferation and invasion. Mol Membr Biol. 25:72-82.
-
(2008)
Mol Membr Biol
, vol.25
, pp. 72-82
-
-
Wulfaenger, J.1
Niedling, S.2
Riemann, D.3
Seliger, B.4
-
62
-
-
34147191991
-
Involvement of aminopeptidase N in enhanced chemosensitivity to paclitaxel in ovarian carcinoma in vitro and in vivo
-
Yamashita M, Kajiyama H, Terauchi M, Shibata K, Ino K, Nawa A, Mizutani S, Kikkawa F. 2007. Involvement of aminopeptidase N in enhanced chemosensitivity to paclitaxel in ovarian carcinoma in vitro and in vivo. Int J Cancer. 120:2243-2250.
-
(2007)
Int J Cancer
, vol.120
, pp. 2243-2250
-
-
Yamashita, M.1
Kajiyama, H.2
Terauchi, M.3
Shibata, K.4
Ino, K.5
Nawa, A.6
Mizutani, S.7
Kikkawa, F.8
-
63
-
-
34748837860
-
Aminopeptidase N/CD13 induces angiogenesis through interaction with a pro-angiogenic protein, galectin-3
-
Yang E, Shim JS, Woo HJ, Kim KW, Kwon HJ. 2007. Aminopeptidase N/CD13 induces angiogenesis through interaction with a pro-angiogenic protein, galectin-3. Biochem Biophys Res Commun. 363:336-341.
-
(2007)
Biochem Biophys Res Commun
, vol.363
, pp. 336-341
-
-
Yang, E.1
Shim, J.S.2
Woo, H.J.3
Kim, K.W.4
Kwon, H.J.5
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