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Volumn 31, Issue SUPPL. 1, 2011, Pages 95-103

Treatment of HBeAg-negative chronic hepatitis B patients with nucleos(t)ide analogues

Author keywords

Adefovir; Entecavir; Hepatitis B; Interferon; Lamivudine; Telbivudine; Tenofovir

Indexed keywords

ADEFOVIR; ALPHA INTERFERON; ENTECAVIR; HEPATITIS B(E) ANTIGEN; LAMIVUDINE; NUCLEOSIDE ANALOG; PEGINTERFERON ALPHA; TELBIVUDINE; TENOFOVIR;

EID: 78650815017     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2010.02392.x     Document Type: Article
Times cited : (13)

References (73)
  • 3
    • 58149296156 scopus 로고    scopus 로고
    • EASL clinical practice guidelines
    • European Association for the Study of the Liver., J Hepatol
    • European Association for the Study of the Liver. EASL clinical practice guidelines: management of chronic hepatitis B. J Hepatol 2009; 50: 227-42.
    • (2009) management of chronic hepatitis B , vol.50 , pp. 227-42
  • 5
    • 51049107683 scopus 로고    scopus 로고
    • Asian-Pacific consensus statement on the management of chronic hepatitis B
    • Hepatol Int
    • Liaw YF, Leung N, Kao JH, et al. Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2008 update. Hepatol Int 2008; 2: 263-83.
    • (2008) a 2008 update , vol.2 , pp. 263-83
    • Liaw, Y.F.1    Leung, N.2    Kao, J.H.3
  • 6
    • 66149173798 scopus 로고    scopus 로고
    • Benefits and risks of nucleoside analog therapy for hepatitis B
    • Dienstag JL. Benefits and risks of nucleoside analog therapy for hepatitis B. Hepatology 2009; 49 (Suppl.): S112-21.
    • (2009) Hepatology , vol.49 , Issue.SUPPL
    • Dienstag, J.L.1
  • 7
    • 0037468421 scopus 로고    scopus 로고
    • Adefovir dipivoxil for the treatment of hepatitis B antigen-positive chronic hepatitis B
    • Marcellin P, Chang TT, Lim SG, et al. Adefovir dipivoxil for the treatment of hepatitis B antigen-positive chronic hepatitis B. N Engl J Med 2003; 348: 808-16.
    • (2003) N Engl J Med , vol.348 , pp. 808-16
    • Marcellin, P.1    Chang, T.T.2    Lim, S.G.3
  • 8
    • 57349095400 scopus 로고    scopus 로고
    • Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B
    • Marcellin P, Heathcote EJ, Buti M, et al. Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B. N Engl J Med 2008; 359: 2442-55.
    • (2008) N Engl J Med , vol.359 , pp. 2442-55
    • Marcellin, P.1    Heathcote, E.J.2    Buti, M.3
  • 9
    • 0037468406 scopus 로고    scopus 로고
    • Adefovir dipivoxil for the treatment of hepatitis B antigen-negative chronic hepatitis B
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Adefovir dipivoxil for the treatment of hepatitis B antigen-negative chronic hepatitis B. N Engl J Med 2003; 348: 800-7.
    • (2003) N Engl J Med , vol.348 , pp. 800-7
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 10
    • 0032499913 scopus 로고    scopus 로고
    • A one-year trial of lamivudine for chronic hepatitis B. Asia hepatitis lamivudine study group
    • Lai CL, Chien RN, Leung NW, et al. A one-year trial of lamivudine for chronic hepatitis B. Asia hepatitis lamivudine study group. N Engl J Med 1998; 339: 61-8.
    • (1998) N Engl J Med , vol.339 , pp. 61-8
    • Lai, C.L.1    Chien, R.N.2    Leung, N.W.3
  • 11
    • 0033592764 scopus 로고    scopus 로고
    • Lamivudine as initial treatment for chronic hepatitis B in the United States
    • Dienstag JL, Schiff ER, Wright TL, et al. Lamivudine as initial treatment for chronic hepatitis B in the United States. N Engl J Med 1999; 341: 1256-63.
    • (1999) N Engl J Med , vol.341 , pp. 1256-63
    • Dienstag, J.L.1    Schiff, E.R.2    Wright, T.L.3
  • 12
    • 33644818518 scopus 로고    scopus 로고
    • A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B
    • Chang TT, Gish RG, de MAN R, et al. A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N Engl J Med 2006; 354: 1001-10.
    • (2006) N Engl J Med , vol.354 , pp. 1001-10
    • Chang, T.T.1    Gish, R.G.2    de Man, R.3
  • 13
    • 37349120537 scopus 로고    scopus 로고
    • Telbivudine versus lamivudine in patients with chronic hepatitis B
    • Lai CL, Gane E, Liaw YF, et al. Telbivudine versus lamivudine in patients with chronic hepatitis B. N Engl J Med 2007; 357: 2576-88.
    • (2007) N Engl J Med , vol.357 , pp. 2576-88
    • Lai, C.L.1    Gane, E.2    Liaw, Y.F.3
  • 14
    • 33644822860 scopus 로고    scopus 로고
    • Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B
    • Lai CL, ShouvaL D, Lok AS, et al. Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B. N Engl J Med 2006; 354: 1011-20.
    • (2006) N Engl J Med , vol.354 , pp. 1011-20
    • Lai, C.L.1    ShouvaL, D.2    Lok, A.S.3
  • 15
    • 0001327133 scopus 로고    scopus 로고
    • Adverse events associated with interferon-alfa therapy in patients with chronic viral hepatitis
    • Vinayek R, Shakil O. Adverse events associated with interferon-alfa therapy in patients with chronic viral hepatitis. Viral Hep Rev 1997; 3: 167-77.
    • (1997) Viral Hep Rev , vol.3 , pp. 167-77
    • Vinayek, R.1    Shakil, O.2
  • 17
    • 21244447705 scopus 로고    scopus 로고
    • Peginterferon alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B
    • Lau GKK, Piratvisuth T, Luo KX, et al. Peginterferon alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B. N Engl J Med 2005; 352: 2682-95.
    • (2005) N Engl J Med , vol.352 , pp. 2682-95
    • Lau, G.K.K.1    Piratvisuth, T.2    Luo, K.X.3
  • 18
    • 4544239807 scopus 로고    scopus 로고
    • Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B
    • Marcellin P, Lau GK, Bonino F, et al. Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B. N Engl J Med 2004; 351: 1206-17.
    • (2004) N Engl J Med , vol.351 , pp. 1206-17
    • Marcellin, P.1    Lau, G.K.2    Bonino, F.3
  • 19
    • 66149190942 scopus 로고    scopus 로고
    • Side effects of long-term oral antiviral therapy for hepatitis B
    • Fontana RJ. Side effects of long-term oral antiviral therapy for hepatitis B. Hepatology 2009; 49: S185-95.
    • (2009) Hepatology , vol.49
    • Fontana, R.J.1
  • 20
    • 10744225554 scopus 로고    scopus 로고
    • Long-term safety of lamivudine treatment in patients with chronic hepatitis B
    • Lok AS, Lai CL, Leung N, et al. Long-term safety of lamivudine treatment in patients with chronic hepatitis B. Gastroenterology 2003; 125: 1714-22.
    • (2003) Gastroenterology , vol.125 , pp. 1714-22
    • Lok, A.S.1    Lai, C.L.2    Leung, N.3
  • 21
    • 33845671388 scopus 로고    scopus 로고
    • Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years. Gastroenterology 2006; 131: 1743-51.
    • (2006) Gastroenterology , vol.131 , pp. 1743-51
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 23
    • 77950613329 scopus 로고    scopus 로고
    • Three years of tenofovir disoproxil (TDF) treatment in HBeAg-positive patients (HBeAg+) with chronic hepatitis B (study 103), preliminary analysis
    • Heathcote EJ, Gane EJ, de Man RA, et al. Three years of tenofovir disoproxil (TDF) treatment in HBeAg-positive patients (HBeAg+) with chronic hepatitis B (study 103), preliminary analysis. Hepatology 2009; 50 (Suppl.): 533A.
    • (2009) Hepatology , vol.50 , Issue.SUPPL
    • Heathcote, E.J.1    Gane, E.J.2    de Man, R.A.3
  • 24
    • 77956627491 scopus 로고    scopus 로고
    • Three years of tenofovir disoproxil fumarate (TDF) treatment in HBeAg-negative patients with chronic hepatitis B (study 102); preliminary analysis
    • Marcellin P, Buti M, Krastev Z, et al. Three years of tenofovir disoproxil fumarate (TDF) treatment in HBeAg-negative patients with chronic hepatitis B (study 102); preliminary analysis. Hepatology 2009; 50 (Suppl.): 532A.
    • (2009) Hepatology , vol.50 , Issue.SUPPL
    • Marcellin, P.1    Buti, M.2    Krastev, Z.3
  • 25
    • 0033012793 scopus 로고    scopus 로고
    • Efficacy of lamivudine in patients with hepatitis B e antigen-negative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis B
    • Tassopoulos NC, Volpes R, Pastore G, et al. Efficacy of lamivudine in patients with hepatitis B e antigen-negative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis B. Hepatology 1999; 29: 889-96.
    • (1999) Hepatology , vol.29 , pp. 889-96
    • Tassopoulos, N.C.1    Volpes, R.2    Pastore, G.3
  • 26
    • 0036288645 scopus 로고    scopus 로고
    • Course of virologic breakthroughs under long-term lamivudine in HBeAg-negative precore mutant HBV liver disease
    • Papatheodoridis GV, Dimou E, Laras A, Papadimitropoulos V, Hadziyannis SJ. Course of virologic breakthroughs under long-term lamivudine in HBeAg-negative precore mutant HBV liver disease. Hepatology 2002; 36: 219-26.
    • (2002) Hepatology , vol.36 , pp. 219-26
    • Papatheodoridis, G.V.1    Dimou, E.2    Laras, A.3    Papadimitropoulos, V.4    Hadziyannis, S.J.5
  • 28
    • 4744354693 scopus 로고    scopus 로고
    • Mechanism of viral persistence and resistance to nucleoside and nucleotide analogs in chronic hepatitis B virus infection
    • Zoulim F. Mechanism of viral persistence and resistance to nucleoside and nucleotide analogs in chronic hepatitis B virus infection. Antiviral Res 2004; 64: 1-15.
    • (2004) Antiviral Res , vol.64 , pp. 1-15
    • Zoulim, F.1
  • 30
    • 0034235528 scopus 로고    scopus 로고
    • Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B
    • Liaw Y-F, Leung NWY, Chang T-T, et al. Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B. Gastroenterology 2000; 119: 172-80.
    • (2000) Gastroenterology , vol.119 , pp. 172-80
    • Liaw, Y.1    Leung, N.W.Y.2    Chang, T.3
  • 31
    • 21344460718 scopus 로고    scopus 로고
    • Outcome of hepatitis B e antigen-negative chronic hepatitis B on long-term nucleos(t)ide analog therapy starting with lamivudine
    • Papatheodoridis GV, Dimou E, Dimakopoulos K, et al. Outcome of hepatitis B e antigen-negative chronic hepatitis B on long-term nucleos(t)ide analog therapy starting with lamivudine. Hepatology 2005; 42: 121-9.
    • (2005) Hepatology , vol.42 , pp. 121-9
    • Papatheodoridis, G.V.1    Dimou, E.2    Dimakopoulos, K.3
  • 32
    • 4644295202 scopus 로고    scopus 로고
    • Clinical outcome of HBeAg-negative chronic hepatitis B in relation to virological response to lamivudine
    • Di Marco V, Marzano A, Lampertico P, et al. Clinical outcome of HBeAg-negative chronic hepatitis B in relation to virological response to lamivudine. Hepatology 2004; 40: 883-91.
    • (2004) Hepatology , vol.40 , pp. 883-91
    • Di Marco, V.1    Marzano, A.2    Lampertico, P.3
  • 33
    • 0034802516 scopus 로고    scopus 로고
    • Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy
    • Yuen MF, Sablon E, Hui CK, et al. Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy. Hepatology 2001; 34: 785-91.
    • (2001) Hepatology , vol.34 , pp. 785-91
    • Yuen, M.F.1    Sablon, E.2    Hui, C.K.3
  • 37
    • 45549103065 scopus 로고    scopus 로고
    • Entecavir at five years shows long-term maintenance of high genetic barrier to hepatitis B virus resistance
    • Tenney D, Pokorowski KA, Rose RE, et al. Entecavir at five years shows long-term maintenance of high genetic barrier to hepatitis B virus resistance. Hepatol Int 2008; 2: S77.
    • (2008) Hepatol Int , vol.2
    • Tenney, D.1    Pokorowski, K.A.2    Rose, R.E.3
  • 38
    • 35649020315 scopus 로고    scopus 로고
    • Entecavir therapy for up to 96 weeks in patients with HBeAg-positive chronic hepatitis B
    • Gish RG, Lok AS, Chang TT, et al. Entecavir therapy for up to 96 weeks in patients with HBeAg-positive chronic hepatitis B. Gastroenterology 2007; 133: 1437-44.
    • (2007) Gastroenterology , vol.133 , pp. 1437-44
    • Gish, R.G.1    Lok, A.S.2    Chang, T.T.3
  • 39
    • 33847666703 scopus 로고    scopus 로고
    • Entecavir maintained virologic suppression through 3 years of treatment in antiviral naive HBeAg(+) patients (ETV022/901)
    • Chang TT, Chao Y-C, Kayamakoglou S, et al. Entecavir maintained virologic suppression through 3 years of treatment in antiviral naive HBeAg(+) patients (ETV022/901). Hepatology 2006; 44 (Suppl. 1): 229A.
    • (2006) Hepatology , vol.44 , Issue.SUPPL. 1
    • Chang, T.T.1    Chao, Y.2    Kayamakoglou, S.3
  • 40
    • 33748625220 scopus 로고    scopus 로고
    • Continued virologic improvement through 96 weeks of entecavir treatment in HBeAg(-) chronic hepatitis B patients (Study ETV-027)
    • Poordad F, Dieterich DT, Min AD, et al. Continued virologic improvement through 96 weeks of entecavir treatment in HBeAg(-) chronic hepatitis B patients (Study ETV-027). Gastroenterology 2006; 130 (Suppl. 1): A-848.
    • (2006) Gastroenterology , vol.130 , Issue.SUPPL. 1
    • Poordad, F.1    Dieterich, D.T.2    Min, A.D.3
  • 41
    • 33749170143 scopus 로고    scopus 로고
    • Resistance to adefovir dipivoxil in lamivudine resistant chronic hepatitis B patients treated with adefovir dipivoxil
    • Yeon JE, Yoo W, Hong SP, et al. Resistance to adefovir dipivoxil in lamivudine resistant chronic hepatitis B patients treated with adefovir dipivoxil. Gut 2006; 55: 1488-95.
    • (2006) Gut , vol.55 , pp. 1488-95
    • Yeon, J.E.1    Yoo, W.2    Hong, S.P.3
  • 42
    • 33847709539 scopus 로고    scopus 로고
    • Adding-on versus switching-to adefovir therapy in lamivudine resistant HBeAg-negative chronic hepatitis B
    • Rapti I, Dimou E, Mitsoula P, Hadziyannis SJ. Adding-on versus switching-to adefovir therapy in lamivudine resistant HBeAg-negative chronic hepatitis B. Hepatology 2007; 45: 307-13.
    • (2007) Hepatology , vol.45 , pp. 307-13
    • Rapti, I.1    Dimou, E.2    Mitsoula, P.3    Hadziyannis, S.J.4
  • 43
    • 32444438958 scopus 로고    scopus 로고
    • Adefovir rapidly suppresses hepatitis B in HBeAg-negative patients developing genotypic resistance to lamivudine
    • Lampertico P, Vigano P, Manenti E, et al. Adefovir rapidly suppresses hepatitis B in HBeAg-negative patients developing genotypic resistance to lamivudine. Hepatology 2005; 42: 1414-9.
    • (2005) Hepatology , vol.42 , pp. 1414-9
    • Lampertico, P.1    Vigano, P.2    Manenti, E.3
  • 44
    • 37549047969 scopus 로고    scopus 로고
    • Long-term therapy with adefovir dipivoxil in hepatitis B e antigen-negative patients developing resistance to lamivudine
    • Manolakopoulos S, Bethanis S, Koutsounas S, et al. Long-term therapy with adefovir dipivoxil in hepatitis B e antigen-negative patients developing resistance to lamivudine. Aliment Pharmacol Ther 2008; 27: 266-73.
    • (2008) Aliment Pharmacol Ther , vol.27 , pp. 266-73
    • Manolakopoulos, S.1    Bethanis, S.2    Koutsounas, S.3
  • 45
    • 33747041958 scopus 로고    scopus 로고
    • Tenofovir for patients with lamivudine resistant hepatitis B virus (HBV) infection and high HBV DNA level during adefovir therapy
    • van Bommel F, Zollner B, Sarrazin C, et al. Tenofovir for patients with lamivudine resistant hepatitis B virus (HBV) infection and high HBV DNA level during adefovir therapy. Hepatology 2006; 44: 318-25.
    • (2006) Hepatology , vol.44 , pp. 318-25
    • van Bommel, F.1    Zollner, B.2    Sarrazin, C.3
  • 46
    • 73449121925 scopus 로고    scopus 로고
    • Long-term efficacy of tenofovir monotherapy for hepatitis B virus-monoinfected patients after failure of nucleoside/nucleotide analogues
    • van Bommel F, De Man RA, Wedemeyer H, et al. Long-term efficacy of tenofovir monotherapy for hepatitis B virus-monoinfected patients after failure of nucleoside/nucleotide analogues. Hepatology 2010; 51: 73-80.
    • (2010) Hepatology , vol.51 , pp. 73-80
    • van Bommel, F.1    De Man, R.A.2    Wedemeyer, H.3
  • 47
    • 54249162685 scopus 로고    scopus 로고
    • Tenofovir disoproxil fumarate (TDF) versus emtricitabine plus TDF for treatment of chronic hepatitis B (CHB) in subjects with persistent viral replication receiving adefovir dipivoxil (ADV)
    • Berg T, Moller B, Trinh H, et al. Tenofovir disoproxil fumarate (TDF) versus emtricitabine plus TDF for treatment of chronic hepatitis B (CHB) in subjects with persistent viral replication receiving adefovir dipivoxil (ADV). J Hepatol 2008; 48 (Suppl. 2): S34.
    • (2008) J Hepatol , vol.48 , Issue.SUPPL. 2
    • Berg, T.1    Moller, B.2    Trinh, H.3
  • 48
    • 30344458192 scopus 로고    scopus 로고
    • Cellular and virological mechanisms of HBV drug resistance
    • Locarnini S, Mason WS. Cellular and virological mechanisms of HBV drug resistance. J Hepatol 2006; 44: 422-31.
    • (2006) J Hepatol , vol.44 , pp. 422-31
    • Locarnini, S.1    Mason, W.S.2
  • 49
    • 55449100302 scopus 로고    scopus 로고
    • Resistance issues in treating chronic hepatitis B
    • Papatheodoridis GV, Deutsch M. Resistance issues in treating chronic hepatitis B. Future Microbiol 2008; 3: 525-38.
    • (2008) Future Microbiol , vol.3 , pp. 525-38
    • Papatheodoridis, G.V.1    Deutsch, M.2
  • 50
    • 0043124519 scopus 로고    scopus 로고
    • Tenofovir disoproxil fumarate
    • Kumar A. Tenofovir disoproxil fumarate. Drugs 2003; 63: 1609-10.
    • (2003) Drugs , vol.63 , pp. 1609-10
    • Kumar, A.1
  • 51
    • 0029893146 scopus 로고    scopus 로고
    • Long-term follow-up of HBeAg-positive patients treated with interferon alfa for chronic hepatitis B
    • Niederau C, Heintges T, Lange S, et al. Long-term follow-up of HBeAg-positive patients treated with interferon alfa for chronic hepatitis B. N Engl J Med 1996; 334: 1422-7.
    • (1996) N Engl J Med , vol.334 , pp. 1422-7
    • Niederau, C.1    Heintges, T.2    Lange, S.3
  • 52
    • 0034950006 scopus 로고    scopus 로고
    • Interferon-alpha treatment and retreatment of hepatitis B e antigen-negative chronic hepatitis B
    • Manesis EK, Hadziyannis SJ. Interferon-alpha treatment and retreatment of hepatitis B e antigen-negative chronic hepatitis B. Gastroenterology 2001; 121: 101-9.
    • (2001) Gastroenterology , vol.121 , pp. 101-9
    • Manesis, E.K.1    Hadziyannis, S.J.2
  • 53
    • 0035110693 scopus 로고    scopus 로고
    • The long-term outcome of interferon-a treated and untreated patients with HBeAg-negative chronic hepatitis B
    • Papatheodoridis GV, Manesis E, Hadziyannis SJ. The long-term outcome of interferon-a treated and untreated patients with HBeAg-negative chronic hepatitis B. J Hepatol 2001; 34: 306-13.
    • (2001) J Hepatol , vol.34 , pp. 306-13
    • Papatheodoridis, G.V.1    Manesis, E.2    Hadziyannis, S.J.3
  • 54
    • 67349168493 scopus 로고    scopus 로고
    • High rates of HBsAg seroconversion in HBeAg-positive chronic hepatitis B patients responding to interferon
    • J Hepatol
    • Moucari R, Korevaar A, Lada O, et al. High rates of HBsAg seroconversion in HBeAg-positive chronic hepatitis B patients responding to interferon: a long-term follow-up study. J Hepatol 2009; 50: 1084-92.
    • (2009) a long-term follow-up study , vol.50 , pp. 1084-92
    • Moucari, R.1    Korevaar, A.2    Lada, O.3
  • 55
    • 48549107919 scopus 로고    scopus 로고
    • Sustained HBeAg and HBsAg loss after long-term follow-up of HBeAg-positive patients treated with peginterferon alpha-2b
    • Buster EH, Flink HJ, Cakaloglu Y, et al. Sustained HBeAg and HBsAg loss after long-term follow-up of HBeAg-positive patients treated with peginterferon alpha-2b. Gastroenterology 2008; 135: 459-67.
    • (2008) Gastroenterology , vol.135 , pp. 459-67
    • Buster, E.H.1    Flink, H.J.2    Cakaloglu, Y.3
  • 56
    • 66449121130 scopus 로고    scopus 로고
    • Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alpha-2a
    • Marcellin P, Bonino F, Lau GK, et al. Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alpha-2a. Gastroenterology 2009; 136: 2169-79.
    • (2009) Gastroenterology , vol.136 , pp. 2169-79
    • Marcellin, P.1    Bonino, F.2    Lau, G.K.3
  • 57
    • 19944428132 scopus 로고    scopus 로고
    • Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B
    • Lancet
    • Janssen HL, van Zonneveld M, Senturk H, et al. Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial. Lancet 2005; 365: 123-9.
    • (2005) a randomised trial , vol.365 , pp. 123-9
    • Janssen, H.L.1    van Zonneveld, M.2    Senturk, H.3
  • 58
    • 39549114267 scopus 로고    scopus 로고
    • HBeAg and hepatitis B virus DNA as outcome predictors during therapy with peginterferon alfa-2a for HBeAg-positive chronic hepatitis B
    • Fried MW, Piratvisuth T, Lau GK, et al. HBeAg and hepatitis B virus DNA as outcome predictors during therapy with peginterferon alfa-2a for HBeAg-positive chronic hepatitis B. Hepatology 2008; 47: 428-34.
    • (2008) Hepatology , vol.47 , pp. 428-34
    • Fried, M.W.1    Piratvisuth, T.2    Lau, G.K.3
  • 61
    • 77954412012 scopus 로고    scopus 로고
    • Prediction of the response to peg-interferon-alfa in patients with HBeAg positive chronic hepatitis B using decline of HBV DNA during treatment
    • Hansen BE, Buster EH, Steyerberg EW, Lesaffre E, Janssen HL. Prediction of the response to peg-interferon-alfa in patients with HBeAg positive chronic hepatitis B using decline of HBV DNA during treatment. J Med Virol 2010; 82: 1135-42.
    • (2010) J Med Virol , vol.82 , pp. 1135-42
    • Hansen, B.E.1    Buster, E.H.2    Steyerberg, E.W.3    Lesaffre, E.4    Janssen, H.L.5
  • 62
    • 8344277996 scopus 로고    scopus 로고
    • Four years of lamivudine treatment in Chinese patients with chronic hepatitis B
    • Chang TT, Lai CL, Chien RN, et al. Four years of lamivudine treatment in Chinese patients with chronic hepatitis B. J Gastroenterol Hepatol 2004; 19: 1276-82.
    • (2004) J Gastroenterol Hepatol , vol.19 , pp. 1276-82
    • Chang, T.T.1    Lai, C.L.2    Chien, R.N.3
  • 63
    • 51349107091 scopus 로고    scopus 로고
    • Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B
    • Marcellin P, Chang TT, Lim SG, et al. Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. Hepatology 2008; 48: 750-8.
    • (2008) Hepatology , vol.48 , pp. 750-8
    • Marcellin, P.1    Chang, T.T.2    Lim, S.G.3
  • 64
    • 77955964465 scopus 로고    scopus 로고
    • Efficacy and safety outcomes after 4 years of telbivudine treatment in patients with chronic hepatitis B (CHB)
    • Wang Y, Thongsawat S, Gane EJ, et al. Efficacy and safety outcomes after 4 years of telbivudine treatment in patients with chronic hepatitis B (CHB). Hepatology 2009; 50 (Suppl.): 533A.
    • (2009) Hepatology , vol.50 , Issue.SUPPL.
    • Wang, Y.1    Thongsawat, S.2    Gane, E.J.3
  • 65
    • 0033797827 scopus 로고    scopus 로고
    • Hepatitis B e antigen seroconversion after lamivudine therapy is not durable in patients with chronic hepatitis B in Korea
    • Song B-C, Suh DJ, Lee HC, Chung Y-H, Lee YS. Hepatitis B e antigen seroconversion after lamivudine therapy is not durable in patients with chronic hepatitis B in Korea. Hepatology 2000; 32: 803-6.
    • (2000) Hepatology , vol.32 , pp. 803-6
    • Song, B.1    Suh, D.J.2    Lee, H.C.3    Chung, Y.4    Lee, Y.S.5
  • 66
    • 0037381547 scopus 로고    scopus 로고
    • Durability of serologic response after lamivudine treatment of chronic hepatitis B
    • Dienstag JL, Cianciara J, Karayalcin S, et al. Durability of serologic response after lamivudine treatment of chronic hepatitis B. Hepatology 2003; 37: 748-55.
    • (2003) Hepatology , vol.37 , pp. 748-55
    • Dienstag, J.L.1    Cianciara, J.2    Karayalcin, S.3
  • 68
    • 54249142122 scopus 로고    scopus 로고
    • Sustained hepatitis B e antigen seroconversion in patients with chronic hepatitis B after adefovir dipivoxil treatment
    • Clin Infect Dis
    • Wu IC, Shiffman ML, Tong MJ, et al. Sustained hepatitis B e antigen seroconversion in patients with chronic hepatitis B after adefovir dipivoxil treatment: analysis of precore and basal core promoter mutants. Clin Infect Dis 2008; 47: 1305-11.
    • (2008) analysis of precore and basal core promoter mutants , vol.47 , pp. 1305-11
    • Wu, I.C.1    Shiffman, M.L.2    Tong, M.J.3
  • 69
    • 77955485392 scopus 로고    scopus 로고
    • Nucleos(t)ide analogues only induce temporary hepatitis B e antigen seroconversion in most patients with chronic hepatitis B
    • Reijnders JG, Perquin MJ, Zhang N, Hansen BE, Janssen HL. Nucleos(t)ide analogues only induce temporary hepatitis B e antigen seroconversion in most patients with chronic hepatitis B. Gastroenterology 2010; 139: 491-8.
    • (2010) Gastroenterology , vol.139 , pp. 491-8
    • Reijnders, J.G.1    Perquin, M.J.2    Zhang, N.3    Hansen, B.E.4    Janssen, H.L.5
  • 70
    • 33847617729 scopus 로고    scopus 로고
    • Sustained biochemical and virological remission after discontiuation of 4 to 5 years of adefovir dipivoxil (ADV) treatment in HBeAg-negative chronic hepatitis B
    • Hadziyannis SJ, Sevastianos V, Rapti IN, Tassopoulos N. Sustained biochemical and virological remission after discontiuation of 4 to 5 years of adefovir dipivoxil (ADV) treatment in HBeAg-negative chronic hepatitis B. Hepatology 2006; 44 (Suppl. 1): 231A.
    • (2006) Hepatology , vol.44 , Issue.SUPPL. 1
    • Hadziyannis, S.J.1    Sevastianos, V.2    Rapti, I.N.3    Tassopoulos, N.4
  • 71
    • 38749126832 scopus 로고    scopus 로고
    • Virologic monitoring of hepatitis B virus therapy in clinical trials and practice
    • Gastroenterology
    • Pawlotsky JM, Dusheiko G, Hatzakis A, et al. Virologic monitoring of hepatitis B virus therapy in clinical trials and practice: recommendations for a standardized approach. Gastroenterology 2008; 134: 405-15.
    • (2008) recommendations for a standardized approach , vol.134 , pp. 405-15
    • Pawlotsky, J.M.1    Dusheiko, G.2    Hatzakis, A.3
  • 72
    • 19544391413 scopus 로고    scopus 로고
    • Lamivudine for patients with chronic hepatitis B and advanced liver disease
    • Liaw YF, Sung JJ, Chow WC, et al. Lamivudine for patients with chronic hepatitis B and advanced liver disease. N Engl J Med 2004; 351: 1521-31.
    • (2004) N Engl J Med , vol.351 , pp. 1521-31
    • Liaw, Y.F.1    Sung, J.J.2    Chow, W.C.3
  • 73
    • 77955306935 scopus 로고    scopus 로고
    • Incidence of hepatocellular carcinoma in chronic hepatitis B patients receiving nucleos(t)ide therapy
    • J Hepatol
    • Papatheodoridis GV, Lampertico P, Manolakopoulos S, Lok A. Incidence of hepatocellular carcinoma in chronic hepatitis B patients receiving nucleos(t)ide therapy: a systematic review. J Hepatol 2010; 53: 348-56.
    • (2010) a systematic review , vol.53 , pp. 348-56
    • Papatheodoridis, G.V.1    Lampertico, P.2    Manolakopoulos, S.3    Lok, A.4


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