-
1
-
-
0030707941
-
Hepatitis B virus infection
-
Lee WM: Hepatitis B virus infection. N. Engl. J. Med. 337, 1733-1745 (1997).
-
(1997)
N. Engl. J. Med
, vol.337
, pp. 1733-1745
-
-
Lee, W.M.1
-
2
-
-
0034078342
-
Hepatitis B: An important public health issue
-
Maddrey WC: Hepatitis B: an important public health issue. J. Med. Virol. 61, 362-366 (2000).
-
(2000)
J. Med. Virol
, vol.61
, pp. 362-366
-
-
Maddrey, W.C.1
-
3
-
-
33646369150
-
Hepatitis B e antigen negative chronic hepatitis B - natural history and treatment
-
Hadziyannis SJ, Papatheodoridis GV: Hepatitis B e antigen negative chronic hepatitis B - natural history and treatment. Semin. Liver Dis. 26, 130-141 (2006).
-
(2006)
Semin. Liver Dis
, vol.26
, pp. 130-141
-
-
Hadziyannis, S.J.1
Papatheodoridis, G.V.2
-
4
-
-
0029115078
-
Global programme for control of hepatitis B infection
-
Kane M: Global programme for control of hepatitis B infection. Vaccine 13, S47-S49 (1995).
-
(1995)
Vaccine
, vol.13
-
-
Kane, M.1
-
5
-
-
0032499913
-
one-year trial of lamivudine for chronic hepatitis B. Asia Hepatitis Lamivudine Study Group
-
Lai CL, Chien RN, Leung NW et al.: one-year trial of lamivudine for chronic hepatitis B. Asia Hepatitis Lamivudine Study Group. N. Engl. J. Med. 339, 61-68 (1998).
-
(1998)
N. Engl. J. Med
, vol.339
, pp. 61-68
-
-
Lai, C.L.1
Chien, R.N.2
Leung, N.W.3
-
6
-
-
0033012793
-
Efficacy of lamivudine in patients with hepatitis B e antigen-negative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis B
-
Tassopoulos NC, Volpes R, Pastore G et al.: Efficacy of lamivudine in patients with hepatitis B e antigen-negative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis B. Hepatology 29, 889-896 (1999).
-
(1999)
Hepatology
, vol.29
, pp. 889-896
-
-
Tassopoulos, N.C.1
Volpes, R.2
Pastore, G.3
-
7
-
-
0037468421
-
Adefovir dipivoxil for the treatment of hepatitis B antigen-positive chronic hepatitis B
-
Marcellin P, Chang TT, Lim SG et al.: Adefovir dipivoxil for the treatment of hepatitis B antigen-positive chronic hepatitis B. N. Engl. J. Med. 348, 808-816 (2003).
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 808-816
-
-
Marcellin, P.1
Chang, T.T.2
Lim, S.G.3
-
8
-
-
0037468406
-
Adefovir dipivoxil for the treatment of hepatitis B antigen-negative chronic hepatitis B
-
Hadziyannis SJ, Tassopoulos NC, Heathcote EJ et al.: Adefovir dipivoxil for the treatment of hepatitis B antigen-negative chronic hepatitis B. N. Engl. J. Med. 348, 800-807 (2003).
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 800-807
-
-
Hadziyannis, S.J.1
Tassopoulos, N.C.2
Heathcote, E.J.3
-
9
-
-
33644818518
-
A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B
-
Chang TT, Gish RG, de Man R et al.: A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N. Engl. J. Med. 354, 1001-1010 (2006).
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 1001-1010
-
-
Chang, T.T.1
Gish, R.G.2
de Man, R.3
-
10
-
-
33644822860
-
Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B
-
Lai CL, Shouval D, Lok AS et al.: Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B. N. Engl. J. Med. 354, 1011-1020 (2006).
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 1011-1020
-
-
Lai, C.L.1
Shouval, D.2
Lok, A.S.3
-
11
-
-
37349120537
-
Telbivudine versus lamivudine in patients with chronic hepatitis B
-
Lai CL, Gane E, Liaw YF et al.: Telbivudine versus lamivudine in patients with chronic hepatitis B. N. Engl. J. Med. 357, 2576-2588 (2007).
-
(2007)
N. Engl. J. Med
, vol.357
, pp. 2576-2588
-
-
Lai, C.L.1
Gane, E.2
Liaw, Y.F.3
-
12
-
-
39149122593
-
A randomized, double-blind, comparison of tenofovir DF (TDF) versus adefovir dipivoxil (ADV) for the treatment of HBeAg positive chronic hepatitis B (CHB): Study GS-US-174-0103
-
Heathcote J, Gane E, de Man R et al.: A randomized, double-blind, comparison of tenofovir DF (TDF) versus adefovir dipivoxil (ADV) for the treatment of HBeAg positive chronic hepatitis B (CHB): study GS-US-174-0103. Hepatology 46(Suppl. 1), 861A (2007).
-
(2007)
Hepatology
, vol.46
, Issue.SUPPL. 1
-
-
Heathcote, J.1
Gane, E.2
de Man, R.3
-
13
-
-
39149111361
-
A randomized, double-blind, comparison of tenofovir DF (TDF) versus adefovir dipivoxil (ADV) for the treatment of HBeAg-negative chronic hepatitis B (CHB): Study GS-US-174-0102
-
Marcellin P, Buti M, Krastev Z et al.: A randomized, double-blind, comparison of tenofovir DF (TDF) versus adefovir dipivoxil (ADV) for the treatment of HBeAg-negative chronic hepatitis B (CHB): study GS-US-174-0102. Hepatology 46(Suppl. 1), 290A (2007).
-
(2007)
Hepatology
, vol.46
, Issue.SUPPL. 1
-
-
Marcellin, P.1
Buti, M.2
Krastev, Z.3
-
14
-
-
39049159624
-
Therapeutic strategies in the management of patients with chronic hepatitis B
-
Papatheodoridis GV, Manolakopoulos S, Dusheiko G, Archimandritis AJ: Therapeutic strategies in the management of patients with chronic hepatitis B. Lancet Infect. Dis. 8, 167-178 (2008).
-
(2008)
Lancet Infect. Dis
, vol.8
, pp. 167-178
-
-
Papatheodoridis, G.V.1
Manolakopoulos, S.2
Dusheiko, G.3
Archimandritis, A.J.4
-
16
-
-
0027378724
-
Effect of α-interferon in patients with hepatitis B e antigen-positive chronic hepatitis B. A meta-analysis
-
Wong DKH, Cheung AM, O'Rourke K, Naylor CD, Detsky AS, Heathcote J: Effect of α-interferon in patients with hepatitis B e antigen-positive chronic hepatitis B. A meta-analysis. Ann. Intern. Med. 119, 312-323 (1993).
-
(1993)
Ann. Intern. Med
, vol.119
, pp. 312-323
-
-
Wong, D.K.H.1
Cheung, A.M.2
O'Rourke, K.3
Naylor, C.D.4
Detsky, A.S.5
Heathcote, J.6
-
17
-
-
0029893146
-
Long-term follow-up of HBeAg-positive patients treated with interferon-α for chronic hepatitis B
-
Niederau C, Heintges T, Lange S et al.: Long-term follow-up of HBeAg-positive patients treated with interferon-α for chronic hepatitis B. N. Engl. J. Med. 334, 1422-1427 (1996).
-
(1996)
N. Engl. J. Med
, vol.334
, pp. 1422-1427
-
-
Niederau, C.1
Heintges, T.2
Lange, S.3
-
18
-
-
0034950006
-
Interferon- α treatment and retreatment of hepatitis B e antigen-negative chronic hepatitis B
-
Manesis EK, Hadziyannis SJ: Interferon- α treatment and retreatment of hepatitis B e antigen-negative chronic hepatitis B. Gastroenterology 121, 101-109 (2001).
-
(2001)
Gastroenterology
, vol.121
, pp. 101-109
-
-
Manesis, E.K.1
Hadziyannis, S.J.2
-
19
-
-
0035110693
-
The long-term outcome of interferon-α treated and untreated patients with HBeAg-negative chronic hepatitis B
-
Papatheodoridis GV, Manesis E, Hadziyannis SJ: The long-term outcome of interferon-α treated and untreated patients with HBeAg-negative chronic hepatitis B. J. Hepatol. 34, 306-313 (2001).
-
(2001)
J. Hepatol
, vol.34
, pp. 306-313
-
-
Papatheodoridis, G.V.1
Manesis, E.2
Hadziyannis, S.J.3
-
20
-
-
21244447705
-
Peginterferon α-2a. lamivudine, and the combination for HBeAg-positive chronic hepatitis B
-
Lau GKK, Piratvisuth T, Luo KX et al.: Peginterferon α-2a. lamivudine, and the combination for HBeAg-positive chronic hepatitis B. N. Engl. J. Med. 352, 2682-2695 (2005).
-
(2005)
N. Engl. J. Med
, vol.352
, pp. 2682-2695
-
-
Lau, G.K.K.1
Piratvisuth, T.2
Luo, K.X.3
-
21
-
-
19944428132
-
Pegylated interferon α-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: A randomised trial
-
Janssen HL, van Zonneveld M, Senturk H, et al.: Pegylated interferon α-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial. Lancet 365, 123-129 (2005).
-
(2005)
Lancet
, vol.365
, pp. 123-129
-
-
Janssen, H.L.1
van Zonneveld, M.2
Senturk, H.3
-
22
-
-
4544239807
-
Peginterferon α-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B
-
Marcellin P, Lau GK, Bonino F et al.: Peginterferon α-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B. N. Engl. J. Med. 351, 1206-1217 (2004).
-
(2004)
N. Engl. J. Med
, vol.351
, pp. 1206-1217
-
-
Marcellin, P.1
Lau, G.K.2
Bonino, F.3
-
23
-
-
0028894411
-
Efficacy of lamivudine on replication of hepatitis B virus in HIV-infected patients
-
Benhamou Y, Dohin E, Lunel-Fabiani F et al.: Efficacy of lamivudine on replication of hepatitis B virus in HIV-infected patients. Lancet 345, 396-397 (1995).
-
(1995)
Lancet
, vol.345
, pp. 396-397
-
-
Benhamou, Y.1
Dohin, E.2
Lunel-Fabiani, F.3
-
24
-
-
0032783736
-
Lamivudine. A review of its therapeutic potential in chronic hepatitis B
-
Jarvis B, Faulds D: Lamivudine. A review of its therapeutic potential in chronic hepatitis B. Drugs 58, 101-141 (1999).
-
(1999)
Drugs
, vol.58
, pp. 101-141
-
-
Jarvis, B.1
Faulds, D.2
-
25
-
-
0036314982
-
Nucleoside analogues for chronic hepatitis B: Antiviral efficacy and viral resistance
-
Papatheodoridis GV, Dimou E, Papadimitropoulos V: Nucleoside analogues for chronic hepatitis B: antiviral efficacy and viral resistance. Am. J. Gastroenterol. 97. 1618-1628 (2002).
-
(2002)
Am. J. Gastroenterol
, vol.97
, pp. 1618-1628
-
-
Papatheodoridis, G.V.1
Dimou, E.2
Papadimitropoulos, V.3
-
26
-
-
4744354693
-
Mechanism of viral persistence and resistance to nucleoside and nucleotide analogs in chronic hepatitis B virus infection
-
Zoulim F: Mechanism of viral persistence and resistance to nucleoside and nucleotide analogs in chronic hepatitis B virus infection. Antiviral. Res. 64, 1-15 (2004).
-
(2004)
Antiviral. Res
, vol.64
, pp. 1-15
-
-
Zoulim, F.1
-
27
-
-
32444435768
-
HBV drug resistance: Mechanisms, detection and interpretation
-
Shaw T, Bartholomeusz A, Locarnini S: HBV drug resistance: mechanisms, detection and interpretation. J. Hepatol. 44, 593-606 (2006).
-
(2006)
J. Hepatol
, vol.44
, pp. 593-606
-
-
Shaw, T.1
Bartholomeusz, A.2
Locarnini, S.3
-
28
-
-
0025061039
-
Mutational analysis of the hepatitis B virus P gene product: Domain structure and RNAse H activity
-
Radiwell G: Mutational analysis of the hepatitis B virus P gene product: domain structure and RNAse H activity. J. Virol. 64, 613-620 (1990).
-
(1990)
J. Virol
, vol.64
, pp. 613-620
-
-
Radiwell, G.1
-
29
-
-
0020557417
-
Sequence homology between retroviral reverse transcriptase and putative polymerases of hepatitis B virus and cauliflower mosaic virus
-
Toh H, Hayashida H, Miyata T: Sequence homology between retroviral reverse transcriptase and putative polymerases of hepatitis B virus and cauliflower mosaic virus. Nature 305, 827-829 (1983).
-
(1983)
Nature
, vol.305
, pp. 827-829
-
-
Toh, H.1
Hayashida, H.2
Miyata, T.3
-
30
-
-
2642604727
-
Computer analysis of retroviral pol genes: Assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes
-
Johnson MS, McClure MA, Feng DF et al.: Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes. Proc. Natl Acad. Sci. USA 83, 7648-7652 (1986).
-
(1986)
Proc. Natl Acad. Sci. USA
, vol.83
, pp. 7648-7652
-
-
Johnson, M.S.1
McClure, M.A.2
Feng, D.F.3
-
31
-
-
0035120228
-
Molecular anatomy and pathophysiologic implications of drug resistance in hepatitis B virus infection
-
Doo E, Liang TJ: Molecular anatomy and pathophysiologic implications of drug resistance in hepatitis B virus infection. Gastroenterology 120, 1000-1008 (2001).
-
(2001)
Gastroenterology
, vol.120
, pp. 1000-1008
-
-
Doo, E.1
Liang, T.J.2
-
32
-
-
0027221640
-
Rates of spontaneous mutation among RNA viruses
-
Drake JW: Rates of spontaneous mutation among RNA viruses. Proc. Natl Acad. Sci. USA 90, 4171-4175 (1993).
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 4171-4175
-
-
Drake, J.W.1
-
33
-
-
0029994971
-
Viral dynamics in hepatitis B virus infection
-
Nowak MA, Bonhoeffer S, Hill AM, Boehme R, Thomas HC, McDade H: Viral dynamics in hepatitis B virus infection. Proc. Natl Acad. Sci. USA 93, 4398-4402 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 4398-4402
-
-
Nowak, M.A.1
Bonhoeffer, S.2
Hill, A.M.3
Boehme, R.4
Thomas, H.C.5
McDade, H.6
-
34
-
-
0024316283
-
Mutation rate of the hepadnavirus genome
-
Girones R, Miller RH: Mutation rate of the hepadnavirus genome. Virology 170, 595-597 (1989).
-
(1989)
Virology
, vol.170
, pp. 595-597
-
-
Girones, R.1
Miller, R.H.2
-
35
-
-
7244262077
-
Management of antiviral resistance in patients with chronic hepatitis B
-
Locarnini S, Hatzakis A, Heathcote J et al.: Management of antiviral resistance in patients with chronic hepatitis B. Antivir. Ther. 9, 679-693 (2004).
-
(2004)
Antivir. Ther
, vol.9
, pp. 679-693
-
-
Locarnini, S.1
Hatzakis, A.2
Heathcote, J.3
-
36
-
-
0029817898
-
Mutation in HBV RNA-dependent DNA polymerase confers resistance to lamivudine in vivo
-
Tipples GA, Ma MM, Fischer KP, Bain VG, Kneteman NM, Tyrrell DL: Mutation in HBV RNA-dependent DNA polymerase confers resistance to lamivudine in vivo. Hepatology 24, 714-717 (1996).
-
(1996)
Hepatology
, vol.24
, pp. 714-717
-
-
Tipples, G.A.1
Ma, M.M.2
Fischer, K.P.3
Bain, V.G.4
Kneteman, N.M.5
Tyrrell, D.L.6
-
39
-
-
0036288645
-
Course of virologic breakthroughs under long-term lamivudine in HBeAg-negative precore mutant HBV liver disease
-
Papatheodoridis GV, Dimou E, Laras A, Papadimitropoulos V, Hadziyannis SJ: Course of virologic breakthroughs under long-term lamivudine in HBeAg-negative precore mutant HBV liver disease. Hepatology 36, 219-226 (2002).
-
(2002)
Hepatology
, vol.36
, pp. 219-226
-
-
Papatheodoridis, G.V.1
Dimou, E.2
Laras, A.3
Papadimitropoulos, V.4
Hadziyannis, S.J.5
-
40
-
-
4644295202
-
Clinical outcome of HBeAg-negative chronic hepatitis B in relation to virological response to lamivudine
-
Di Marco V, Marzano A, Lampertico P et al.: Clinical outcome of HBeAg-negative chronic hepatitis B in relation to virological response to lamivudine. Hepatology 40, 883-891 (2004).
-
(2004)
Hepatology
, vol.40
, pp. 883-891
-
-
Di Marco, V.1
Marzano, A.2
Lampertico, P.3
-
41
-
-
0034235528
-
Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B
-
Liaw Y-F, Leung NWY, Chang T-T et al.: Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B. Gastroenterology 119, 172-180 (2000).
-
(2000)
Gastroenterology
, vol.119
, pp. 172-180
-
-
Liaw, Y.-F.1
Leung, N.W.Y.2
Chang, T.-T.3
-
42
-
-
10744225554
-
Long-term safety of lamivudine treatment in patients with chronic hepatitis B
-
Lok AS, Lai CL, Leung N et al.: Long-term safety of lamivudine treatment in patients with chronic hepatitis B. Gastroenterology 125, 1714-1722 (2003).
-
(2003)
Gastroenterology
, vol.125
, pp. 1714-1722
-
-
Lok, A.S.1
Lai, C.L.2
Leung, N.3
-
43
-
-
0034802516
-
Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy
-
Yuen MF, Sablon E, Hui CK, Yuan HJ, Decraemer H, Lai CL: Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy. Hepatology 34, 785-791 (2001).
-
(2001)
Hepatology
, vol.34
, pp. 785-791
-
-
Yuen, M.F.1
Sablon, E.2
Hui, C.K.3
Yuan, H.J.4
Decraemer, H.5
Lai, C.L.6
-
44
-
-
33644771075
-
Lamivudine monotherapy in HBeAg-negative chronic hepatitis B: Prediction of response-breakthrough and long-term clinical outcome
-
Manolakopoulos S, Bethanis S, Elefsiniotis J et al.: Lamivudine monotherapy in HBeAg-negative chronic hepatitis B: prediction of response-breakthrough and long-term clinical outcome. Aliment Pharmacol. Ther. 23, 787-795 (2006).
-
(2006)
Aliment Pharmacol. Ther
, vol.23
, pp. 787-795
-
-
Manolakopoulos, S.1
Bethanis, S.2
Elefsiniotis, J.3
-
45
-
-
55649107891
-
Long-term treatment with lamivudine up to ten years: Predictive value of host and virus related factors for the development of HBV resistance
-
Van Bommel F, Brodzinski A, Mihm U et al.: Long-term treatment with lamivudine up to ten years: predictive value of host and virus related factors for the development of HBV resistance. J. Hepatol. 48(Suppl. 2), S264-S265 (2008).
-
(2008)
J. Hepatol
, vol.48
, Issue.SUPPL. 2
-
-
Van Bommel, F.1
Brodzinski, A.2
Mihm, U.3
-
46
-
-
38049087457
-
Long-term lamivudine therapy reduces the risk of long-term complications of chronic hepatitis B infection even in patients without advanced disease
-
Yuen MF, Seto WK, Chow DH et al.: Long-term lamivudine therapy reduces the risk of long-term complications of chronic hepatitis B infection even in patients without advanced disease. Antivir. Ther. 12, 1295-1303 (2007).
-
(2007)
Antivir. Ther
, vol.12
, pp. 1295-1303
-
-
Yuen, M.F.1
Seto, W.K.2
Chow, D.H.3
-
47
-
-
0034011395
-
Clinical relevance of hepatitis B virus mutations
-
Hunt CM, McGill JM, Allen ML, Condreay LD: Clinical relevance of hepatitis B virus mutations. Hepatology 31, 1037-1044 (2000).
-
(2000)
Hepatology
, vol.31
, pp. 1037-1044
-
-
Hunt, C.M.1
McGill, J.M.2
Allen, M.L.3
Condreay, L.D.4
-
48
-
-
0031780935
-
Identification and characterization of mutations in hepatitis B virus resistant to lamivudine. Lamivudine Clinical Investigation Group
-
Allen MI, Deslauriers M, Andrews CW et al.: Identification and characterization of mutations in hepatitis B virus resistant to lamivudine. Lamivudine Clinical Investigation Group. Hepatology 27, 1670-1677 (1998).
-
(1998)
Hepatology
, vol.27
, pp. 1670-1677
-
-
Allen, M.I.1
Deslauriers, M.2
Andrews, C.W.3
-
49
-
-
33745619248
-
Hepatitis B virus mutations associated with antiviral therapy
-
Bartholomeusz A, Locarnini S: Hepatitis B virus mutations associated with antiviral therapy. J. Med. Virol.. 78(Suppl. 1). S52-S55 (2006).
-
(2006)
J. Med. Virol
, vol.78
, Issue.SUPPL. 1
-
-
Bartholomeusz, A.1
Locarnini, S.2
-
51
-
-
21344460718
-
Outcome of hepatitis B e antigen-negative chronic hepatitis B on long-term nucleos(t)ide analog therapy starting with lamivudine
-
Papatheodoridis GV, Dimou E, Dimakopoulos K et al.: Outcome of hepatitis B e antigen-negative chronic hepatitis B on long-term nucleos(t)ide analog therapy starting with lamivudine. Hepatology 42, 121-129 (2005).
-
(2005)
Hepatology
, vol.42
, pp. 121-129
-
-
Papatheodoridis, G.V.1
Dimou, E.2
Dimakopoulos, K.3
-
52
-
-
0033761078
-
Early detection of viral resistance by determination of hepatitis B virus polymerase mutations in patients treated by lamivudine for chronic hepatitis B
-
Si Ahmed SN, Tavan D, Pichoud C et al.: Early detection of viral resistance by determination of hepatitis B virus polymerase mutations in patients treated by lamivudine for chronic hepatitis B. Hepatology 32, 1078-1088 (2000).
-
(2000)
Hepatology
, vol.32
, pp. 1078-1088
-
-
Si Ahmed, S.N.1
Tavan, D.2
Pichoud, C.3
-
53
-
-
0032783679
-
Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy
-
Liaw YF, Chien RN, Yeh CT, Tsai SL, Chu CM: Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy. Hepatology 30, 567-572 (1999).
-
(1999)
Hepatology
, vol.30
, pp. 567-572
-
-
Liaw, Y.F.1
Chien, R.N.2
Yeh, C.T.3
Tsai, S.L.4
Chu, C.M.5
-
54
-
-
33646369149
-
Antiviral drug resistance: Clinical consequences and molecular aspects
-
Bartholomeusz A, Locarnini SA: Antiviral drug resistance: clinical consequences and molecular aspects. Semin. Liver Dis. 26, 162-170 (2006).
-
(2006)
Semin. Liver Dis
, vol.26
, pp. 162-170
-
-
Bartholomeusz, A.1
Locarnini, S.A.2
-
55
-
-
33746339209
-
A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: An update
-
Keeffe EB, Dieterich DT, Han S-HB et al.: A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: an update. Clin. Gastroenterol. Hepatol. 4. 936-962 (2006).
-
(2006)
Clin. Gastroenterol. Hepatol
, vol.4
, pp. 936-962
-
-
Keeffe, E.B.1
Dieterich, D.T.2
Han, S.-H.B.3
-
56
-
-
4444278380
-
Adefovir dipivoxil in the treatment of chronic hepatitis B virus infection
-
Hadziyannis SJ, Papatheodoridis GV: Adefovir dipivoxil in the treatment of chronic hepatitis B virus infection. Expert Rev. Anti-infect. Ther. 2, 475-483 (2004).
-
(2004)
Expert Rev. Anti-infect. Ther
, vol.2
, pp. 475-483
-
-
Hadziyannis, S.J.1
Papatheodoridis, G.V.2
-
57
-
-
0032997095
-
Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir
-
Cundy KC: Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir. Clin. Pharmacokinet. 36, 127-143 (1999).
-
(1999)
Clin. Pharmacokinet
, vol.36
, pp. 127-143
-
-
Cundy, K.C.1
-
58
-
-
33845671388
-
Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years
-
Hadziyannis SJ, Tassopoulos NC, Heathcote EJ et al.: Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years. Gastroenterology 131, 1743-1751 (2006).
-
(2006)
Gastroenterology
, vol.131
, pp. 1743-1751
-
-
Hadziyannis, S.J.1
Tassopoulos, N.C.2
Heathcote, E.J.3
-
59
-
-
32444438958
-
Adefovir rapidly suppresses hepatitis B in HBeAg-negative patients developing genotypic resistance to lamivudine
-
Lampertico P, Vigano P, Manenti E, Iavarone M, Lunghi G, Colombo M: Adefovir rapidly suppresses hepatitis B in HBeAg-negative patients developing genotypic resistance to lamivudine. Hepatology 42, 1414-1419 (2005).
-
(2005)
Hepatology
, vol.42
, pp. 1414-1419
-
-
Lampertico, P.1
Vigano, P.2
Manenti, E.3
Iavarone, M.4
Lunghi, G.5
Colombo, M.6
-
60
-
-
33749170143
-
Resistance to adefovir dipivoxil in lamivudine resistant chronic hepatitis B patients treated with adefovir dipivoxil
-
Yeon JE, Yoo W, Hong SP et al.: Resistance to adefovir dipivoxil in lamivudine resistant chronic hepatitis B patients treated with adefovir dipivoxil. Gut 55, 1488-1495 (2006).
-
(2006)
Gut
, vol.55
, pp. 1488-1495
-
-
Yeon, J.E.1
Yoo, W.2
Hong, S.P.3
-
61
-
-
33847709539
-
Adding-on versus switching-to adefovir tehrapy in lamivudine resistant HBeAg-negative chronic hepatitis B
-
Rapti I, Dimou E, Mitsoula P, Hadziyannis SJ: Adding-on versus switching-to adefovir tehrapy in lamivudine resistant HBeAg-negative chronic hepatitis B. Hepatology 45, 307-313 (2007).
-
(2007)
Hepatology
, vol.45
, pp. 307-313
-
-
Rapti, I.1
Dimou, E.2
Mitsoula, P.3
Hadziyannis, S.J.4
-
62
-
-
0041853784
-
Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase
-
Angus P, Vaughan R, Xiong S et al.: Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase. Gastroenterology 125, 292-297 (2003).
-
(2003)
Gastroenterology
, vol.125
, pp. 292-297
-
-
Angus, P.1
Vaughan, R.2
Xiong, S.3
-
63
-
-
0030872946
-
Identification of BMS-200475 as a potent and selective inhibitor of hepatitis B virus
-
Innaimo SF, Seifer M, Bisacchi GS, Standring DN, Zahler R, Colonno RJ: Identification of BMS-200475 as a potent and selective inhibitor of hepatitis B virus. Antimicrob. Agents Chemother. 41, 1444-1448 (1997).
-
(1997)
Antimicrob. Agents Chemother
, vol.41
, pp. 1444-1448
-
-
Innaimo, S.F.1
Seifer, M.2
Bisacchi, G.S.3
Standring, D.N.4
Zahler, R.5
Colonno, R.J.6
-
64
-
-
33748625991
-
Entecavir: A review of its use in chronic hepatitis B
-
Robinson DM, Scott LJ, Plosker GL: Entecavir: a review of its use in chronic hepatitis B. Drugs 66, 1605-1622 (2006).
-
(2006)
Drugs
, vol.66
, pp. 1605-1622
-
-
Robinson, D.M.1
Scott, L.J.2
Plosker, G.L.3
-
65
-
-
34848858648
-
Four year assessment of ETV resistance in nucleoside-naive and lamivudine refractory patients
-
S
-
Colonno RJ, Rose RE, Pokornowski K et al.: Four year assessment of ETV resistance in nucleoside-naive and lamivudine refractory patients. J. Hepatol 46(Supp. 1), S294 (2007).
-
(2007)
J. Hepatol
, vol.46
, Issue.SUPP. 1
, pp. 294
-
-
Colonno, R.J.1
Rose, R.E.2
Pokornowski, K.3
-
66
-
-
55649109765
-
Entecavir at five years shows long-term maintenance of high genetic barrier to hepatitis B virus resistance
-
Tenney D, Pokorowski KA, Rose RE et al.: Entecavir at five years shows long-term maintenance of high genetic barrier to hepatitis B virus resistance. APASL Abstr.: PL02 (2008).
-
(2008)
APASL Abstr
-
-
Tenney, D.1
Pokorowski, K.A.2
Rose, R.E.3
-
67
-
-
4344627233
-
Clinical emergence of entecavir-resistant hepatitis B virus requires additional substitutions in virus already resistant to lamivudine
-
Tenney DJ, Levine SM, Rose RE et al.: Clinical emergence of entecavir-resistant hepatitis B virus requires additional substitutions in virus already resistant to lamivudine. Antimicrob. Agents Chemother. 48, 3498-3507 (2004).
-
(2004)
Antimicrob. Agents Chemother
, vol.48
, pp. 3498-3507
-
-
Tenney, D.J.1
Levine, S.M.2
Rose, R.E.3
-
68
-
-
34548346918
-
Telbivudine
-
Keam SJ: Telbivudine. Drugs 67, 1917-1929 (2007).
-
(2007)
Drugs
, vol.67
, pp. 1917-1929
-
-
Keam, S.J.1
-
69
-
-
23244453590
-
A 1-year trial of telbivudine, lamivudine, and the combination in patients with hepatitis B e antigen-positive chronic hepatitis B
-
Lai C-L, Leung N, Teo E-K et al.: A 1-year trial of telbivudine, lamivudine, and the combination in patients with hepatitis B e antigen-positive chronic hepatitis B. Gastroenterology 129, 528-536 (2005).
-
(2005)
Gastroenterology
, vol.129
, pp. 528-536
-
-
Lai, C.-L.1
Leung, N.2
Teo, E.-K.3
-
70
-
-
33846067615
-
Two-years results from the GLOBE trial in patients with hepatitis B: Greater clinical and antiviral efficacy for telbivudine (LdT) vs lamivudine
-
Lai C-L, Gane E, Hsu C-W et al.: Two-years results from the GLOBE trial in patients with hepatitis B: greater clinical and antiviral efficacy for telbivudine (LdT) vs lamivudine. Hepatology 44(Suppl. 1), 222A (2006).
-
(2006)
Hepatology
, vol.44
, Issue.SUPPL. 1
-
-
Lai, C.-L.1
Gane, E.2
Hsu, C.-W.3
-
71
-
-
33847667158
-
Telbivudine GLOBE trial: Maximal early HBV suppression is predictive of optimal two-year efficacy in nucleoside-treated hepatitis B patients
-
Di Bisceglie A, Lai C-L, Gane E et al.: Telbivudine GLOBE trial: Maximal early HBV suppression is predictive of optimal two-year efficacy in nucleoside-treated hepatitis B patients. Hepatology 44(Suppl. 1), 230A-231A (2006).
-
(2006)
Hepatology
, vol.44
, Issue.SUPPL. 1
-
-
Di Bisceglie, A.1
Lai, C.-L.2
Gane, E.3
-
72
-
-
0043124519
-
Tenofovir disoproxil fumarate
-
Kumar A: Tenofovir disoproxil fumarate. Drugs 63, 1609-1610 (2003).
-
(2003)
Drugs
, vol.63
, pp. 1609-1610
-
-
Kumar, A.1
-
73
-
-
30344458192
-
Cellular and virological mechanisms of HBV drug resistance
-
Locarnini S, Mason WS: Cellular and virological mechanisms of HBV drug resistance. J. Hepatol. 44, 422-431 (2006).
-
(2006)
J. Hepatol
, vol.44
, pp. 422-431
-
-
Locarnini, S.1
Mason, W.S.2
-
74
-
-
45549103233
-
Tenofovir disoproxil fumarate (TDF) for the treatment of HBeAg-positive chronic hepatitis B: Week 72 TDF data and week 24 adefovir dipivoxil switch data (Study 103)
-
S
-
Heathcote J, George J, Gordon S et al.: Tenofovir disoproxil fumarate (TDF) for the treatment of HBeAg-positive chronic hepatitis B: week 72 TDF data and week 24 adefovir dipivoxil switch data (Study 103). J. Hepatol. 48(Suppl. 2), S32 (2008).
-
(2008)
J. Hepatol
, vol.48
, Issue.SUPPL. 2
, pp. 32
-
-
Heathcote, J.1
George, J.2
Gordon, S.3
-
75
-
-
45549094638
-
Tenofovir disoproxil fumarate (TDF) for the treatment of HBeAg-negative chronic hepatitis B: Week 72 TDF data and week 24 adefovir dipivoxil switch data (Study 102)
-
S
-
Marcellin P, Jacobson I, Habersetzer F et al.: Tenofovir disoproxil fumarate (TDF) for the treatment of HBeAg-negative chronic hepatitis B: week 72 TDF data and week 24 adefovir dipivoxil switch data (Study 102). J. Hepatol. 48(Suppl. 2), S26 (2008).
-
(2008)
J. Hepatol
, vol.48
, Issue.SUPPL. 2
, pp. 26
-
-
Marcellin, P.1
Jacobson, I.2
Habersetzer, F.3
-
76
-
-
45549101402
-
A multicenter analysis of antiviral response after one year of tenofovir mono-therapy in HBV-monoinfected patients with prior nucleos(t)ide analog experience
-
S
-
Van Bommel F, de Man R, Stein K et al.: A multicenter analysis of antiviral response after one year of tenofovir mono-therapy in HBV-monoinfected patients with prior nucleos(t)ide analog experience. J. Hepatol. 48(Suppl. 2), S32 (2008).
-
(2008)
J. Hepatol
, vol.48
, Issue.SUPPL. 2
, pp. 32
-
-
Van Bommel, F.1
de Man, R.2
Stein, K.3
-
77
-
-
25444459427
-
Selection of hepatitis B virus polymerase mutations in HIV-coinfected patients treated with tenofovir
-
Sheldon J, Camino N, Rodes B et al.: Selection of hepatitis B virus polymerase mutations in HIV-coinfected patients treated with tenofovir. Antivir. Ther. 10, 727-734 (2005).
-
(2005)
Antivir. Ther
, vol.10
, pp. 727-734
-
-
Sheldon, J.1
Camino, N.2
Rodes, B.3
-
78
-
-
33745630702
-
Intracellular metabolism and in vitro activity of tenofovir against hepatitis B virus
-
Delaney WE, Ray AS, Yang H et al.: Intracellular metabolism and in vitro activity of tenofovir against hepatitis B virus. Antimicrob. Agents Chemother. 50, 2471-2477 (2006).
-
(2006)
Antimicrob. Agents Chemother
, vol.50
, pp. 2471-2477
-
-
Delaney, W.E.1
Ray, A.S.2
Yang, H.3
-
79
-
-
10644254769
-
Antiviral therapy of chronic hepatitis B: Can we clear the virus and prevent drug resistance?
-
Zoulim F: Antiviral therapy of chronic hepatitis B: can we clear the virus and prevent drug resistance? Antivir. Chem. Chemother. 15, 299-305 (2004).
-
(2004)
Antivir. Chem. Chemother
, vol.15
, pp. 299-305
-
-
Zoulim, F.1
-
80
-
-
33749461656
-
Selection of a multiple drug-resistant hepatitis B virus strain in a liver-transplanted patient
-
Villet S, Pichoud C, Villeneuve JP, Trepo C, Zoulim F: Selection of a multiple drug-resistant hepatitis B virus strain in a liver-transplanted patient. Gastroenterology 131, 1253-1261 (2006).
-
(2006)
Gastroenterology
, vol.131
, pp. 1253-1261
-
-
Villet, S.1
Pichoud, C.2
Villeneuve, J.P.3
Trepo, C.4
Zoulim, F.5
-
81
-
-
38749126832
-
Virologic monitoring of hepatitis B virus therapy in clinical trials and practice: Recommendations for a standardized approach
-
Pawlotsky JM, Dusheiko G, Hatzakis A et al.: Virologic monitoring of hepatitis B virus therapy in clinical trials and practice: recommendations for a standardized approach. Gastroenterology 134, 405-415 (2008).
-
(2008)
Gastroenterology
, vol.134
, pp. 405-415
-
-
Pawlotsky, J.M.1
Dusheiko, G.2
Hatzakis, A.3
-
82
-
-
9144271733
-
Adefovir dipivoxil alone or in combination with lamivudine in patients with lamivudine-resistant chronic hepatitis B
-
Peters MG, Hann HH, Martin P et al.: Adefovir dipivoxil alone or in combination with lamivudine in patients with lamivudine-resistant chronic hepatitis B. Gastroenterology 126, 91-101 (2004).
-
(2004)
Gastroenterology
, vol.126
, pp. 91-101
-
-
Peters, M.G.1
Hann, H.H.2
Martin, P.3
-
83
-
-
26844500312
-
A dose-ranging study of the efficacy and tolerability of entecavir in lamivudine-refractory chronic hepatitis B patients
-
Chang TT, Gish RG, Hadziyannis SJ et al.: A dose-ranging study of the efficacy and tolerability of entecavir in lamivudine-refractory chronic hepatitis B patients. Gastroenterology 129, 1198-1209 (2005).
-
(2005)
Gastroenterology
, vol.129
, pp. 1198-1209
-
-
Chang, T.T.1
Gish, R.G.2
Hadziyannis, S.J.3
-
84
-
-
0033802362
-
Long-term therapy of chronic hepatitis B with lamivudine
-
Lau DTY, Khokhar MF, Doo E et al.: Long-term therapy of chronic hepatitis B with lamivudine. Hepatology 32, 828-834 (2000).
-
(2000)
Hepatology
, vol.32
, pp. 828-834
-
-
Lau, D.T.Y.1
Khokhar, M.F.2
Doo, E.3
-
85
-
-
24044526915
-
Cross-resistance testing of next-generation nucleosite and nucletide analogues against lamivudine-resistant HBV
-
Yang H, Qi X, Sabogal A, Miller M, Xiong S, Delaney WE IV: Cross-resistance testing of next-generation nucleosite and nucletide analogues against lamivudine-resistant HBV. Antivir. Ther. 10, 625-633 (2005).
-
(2005)
Antivir. Ther
, vol.10
, pp. 625-633
-
-
Yang, H.1
Qi, X.2
Sabogal, A.3
Miller, M.4
Xiong, S.5
Delaney, W.I.6
-
86
-
-
33744531146
-
Entecavir for treatment of lamivudine-refractory, HBeAg-positive chronic hepatitis B
-
Sherman M, Yurdaydin C, Sollano J et al.: Entecavir for treatment of lamivudine-refractory, HBeAg-positive chronic hepatitis B. Gastroenterology 130, 2039-2049 (2006).
-
(2006)
Gastroenterology
, vol.130
, pp. 2039-2049
-
-
Sherman, M.1
Yurdaydin, C.2
Sollano, J.3
-
87
-
-
10644275213
-
Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infection
-
Van Bommel F, Wunsche T, Mauss S et al.: Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infection. Hepatology 40, 1421-1425 (2004).
-
(2004)
Hepatology
, vol.40
, pp. 1421-1425
-
-
Van Bommel, F.1
Wunsche, T.2
Mauss, S.3
-
88
-
-
33747041958
-
Tenofovir for patients with lamivudine resistant hepatitis B virus (HBV) infection and high HBV DNA level during adefovir therapy
-
Van Bommel F, Zollner B, Sarrazin C et al.: Tenofovir for patients with lamivudine resistant hepatitis B virus (HBV) infection and high HBV DNA level during adefovir therapy. Hepatology 44, 318-325 (2006).
-
(2006)
Hepatology
, vol.44
, pp. 318-325
-
-
Van Bommel, F.1
Zollner, B.2
Sarrazin, C.3
-
89
-
-
30344449469
-
Virologic response and resistance to adefovir in patients with chronic-hepatitis B
-
Fung SK, Chae HB, Fontana RJ et al.: Virologic response and resistance to adefovir in patients with chronic-hepatitis B. J. Hepatol. 44, 283-290 (2006).
-
(2006)
J. Hepatol
, vol.44
, pp. 283-290
-
-
Fung, S.K.1
Chae, H.B.2
Fontana, R.J.3
-
90
-
-
0347361546
-
Rescue therapy for drug resistant hepatitis B: Another argument for combination chemotherapy?
-
Shaw T, Bowden S, Locarnini S: Rescue therapy for drug resistant hepatitis B: another argument for combination chemotherapy? Gastroenterology 126, 343-347 (2004).
-
(2004)
Gastroenterology
, vol.126
, pp. 343-347
-
-
Shaw, T.1
Bowden, S.2
Locarnini, S.3
-
91
-
-
32444435472
-
Five years of sequential LAM to LAM+ADV therapy suppresses HBV replication in most HBeAg-negative cirrhotics, preventing decompensation but not hepatocellular carcinoma
-
Lampertico P, Vigano P, Manenti E, Iavarone M, Lunghi G, Colombo M: Five years of sequential LAM to LAM+ADV therapy suppresses HBV replication in most HBeAg-negative cirrhotics, preventing decompensation but not hepatocellular carcinoma. Hepatology 42(Suppl. 1), 582A-583A (2005).
-
(2005)
Hepatology
, vol.42
, Issue.SUPPL. 1
-
-
Lampertico, P.1
Vigano, P.2
Manenti, E.3
Iavarone, M.4
Lunghi, G.5
Colombo, M.6
-
92
-
-
54249162685
-
Tenofovir disoproxil fumarate (TDF) versus emtricitabine plus TDF for treatment of chronic hepatitis B (CHB) in subjects with persistent viral replication receiving adefovir dipivoxil (ADV)
-
S
-
Berg T, Moller B, Trinh H et al.: Tenofovir disoproxil fumarate (TDF) versus emtricitabine plus TDF for treatment of chronic hepatitis B (CHB) in subjects with persistent viral replication receiving adefovir dipivoxil (ADV). J. Hepatol. 48(Suppl. 2), S34 (2008).
-
(2008)
J. Hepatol
, vol.48
, Issue.SUPPL. 2
, pp. 34
-
-
Berg, T.1
Moller, B.2
Trinh, H.3
-
93
-
-
0346243783
-
Selection of a hepatitis B virus strain resistant ot adefovir in a liver transplantation patient
-
Villeneuve JP, Durantel D, Durantel S et al.: Selection of a hepatitis B virus strain resistant ot adefovir in a liver transplantation patient. J. Hepatol. 39, 1085-1089 (2003).
-
(2003)
J. Hepatol
, vol.39
, pp. 1085-1089
-
-
Villeneuve, J.P.1
Durantel, D.2
Durantel, S.3
-
94
-
-
27144488889
-
Incidence and predictors of emergence of adefovir resistant HBV during four years of adefovir dipivoxil (ADV) therapy for patients with chronic hepatitis B (CHB)
-
Locarnini S, Qi X, Arterburn S et al.: Incidence and predictors of emergence of adefovir resistant HBV during four years of adefovir dipivoxil (ADV) therapy for patients with chronic hepatitis B (CHB). J. Hepatol. 42(Suppl. 2), 17 (2005).
-
(2005)
J. Hepatol
, vol.42
, Issue.SUPPL. 2
, pp. 17
-
-
Locarnini, S.1
Qi, X.2
Arterburn, S.3
-
95
-
-
41249103028
-
Impact of hepatitis B virus rtA181V/T mutants on hepatitis B treatment failure
-
Villet S, Pichoud C, Billioud G et al.: Impact of hepatitis B virus rtA181V/T mutants on hepatitis B treatment failure. J. Hepatol. 48, 747-755 (2008).
-
(2008)
J. Hepatol
, vol.48
, pp. 747-755
-
-
Villet, S.1
Pichoud, C.2
Billioud, G.3
-
96
-
-
27744510332
-
Adefovir-resistant hepatitis B can be associated with viral rebound and hepatic decompensation
-
Fung SK, Andreone P, Han SH et al.: Adefovir-resistant hepatitis B can be associated with viral rebound and hepatic decompensation. J. Hepatol. 43, 937-943 (2005).
-
(2005)
J. Hepatol
, vol.43
, pp. 937-943
-
-
Fung, S.K.1
Andreone, P.2
Han, S.H.3
-
97
-
-
20044375767
-
Susceptibility to antivirals of a human HBV strain with mutations conferring resistance to both lamivudine and adefovir
-
Brunelle MN, Jacquard AC, Pichoud C et al.: Susceptibility to antivirals of a human HBV strain with mutations conferring resistance to both lamivudine and adefovir. Hepatology 41, 1391-1398 (2005).
-
(2005)
Hepatology
, vol.41
, pp. 1391-1398
-
-
Brunelle, M.N.1
Jacquard, A.C.2
Pichoud, C.3
-
98
-
-
33646084161
-
Variant of hepatitis B virus with primary resistance to adefovir
-
Schildgen O, Sirma H, Funk A et al.: Variant of hepatitis B virus with primary resistance to adefovir. N. Engl. J. Med. 354, 1807-1812 (2006).
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 1807-1812
-
-
Schildgen, O.1
Sirma, H.2
Funk, A.3
-
99
-
-
55649101397
-
-
Occurrence of primary adefovir resistance mutation in hepatitis B patients with YMDD mutation and lamivudine resistance, 130Suppl. 2
-
Kim DY, Lee JH, Lee DH et al.: Occurrence of primary adefovir resistance mutation in hepatitis B patients with YMDD mutation and lamivudine resistance. Gastroenterology 130(Suppl. 2), A-846 T1843 (2006).
-
(2006)
Gastroenterology
, vol.A-846
-
-
Kim, D.Y.1
Lee, J.H.2
Lee, D.H.3
-
100
-
-
34447124016
-
Adefovir salvage therapy for virologic breakthrough in telbivudine-treated patients from the GLOBE study
-
Gane E, Lai C-L, Min A et al.: Adefovir salvage therapy for virologic breakthrough in telbivudine-treated patients from the GLOBE study. J. Hepatol. 46(Suppl. 1), S187-S188 (2007).
-
(2007)
J. Hepatol
, vol.46
, Issue.SUPPL. 1
-
-
Gane, E.1
Lai, C.-L.2
Min, A.3
|