The long-term outcome of interferon-α treated and untreated patients with HBeAg-negative chronic hepatitis B

Journal of Hepatology

Volumn 34, Issue 2, 2001, Pages 306-313

  Papatheodoridis, George V ^a   Manesis, Emanuel ^a   Hadziyannis, Stephanos J ^a  

^a HIPPOKRATION HOSPITAL   (Greece)

Author keywords

Chronic hepatitis B; Cirrhosis; Decompensation; HBeAg negative; Hepatocellular carcinoma; Interferon; Survival

Indexed keywords

HEPATITIS B(E) ANTIGEN; RECOMBINANT ALPHA INTERFERON;

ADOLESCENT; ADULT; AGED; ARTICLE; CHRONIC HEPATITIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DOSE TIME EFFECT RELATION; DRUG EFFICACY; FEMALE; HEPATITIS B; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOTHERAPY; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REMISSION; SURVIVAL;

ADOLESCENT; ADULT; AGE FACTORS; AGED; CARCINOMA, HEPATOCELLULAR; COHORT STUDIES; DISEASE-FREE SURVIVAL; FEMALE; HEPATITIS B E ANTIGENS; HEPATITIS B, CHRONIC; HUMANS; INTERFERON TYPE I, RECOMBINANT; LIVER NEOPLASMS; MALE; MIDDLE AGED; SURVIVAL RATE;

EID: 0035110693     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(00)00094-5     Document Type: Article

References (27)

1. Hepatitis B e antigen negative chronic hepatitis B: From clinical recognition to pathogenesis and treatment
2. Incidence and clinical significance of hepatitis B virus precore gene translation initiation mutations in e antigen-negative patients
3. The treatment of chronic viral hepatitis
4. Antiviral chemotherapy for the treatment of hepatitis B virus infections
5. Effect of alpha-interferon in patients with hepatitis B e antigen-positive chronic hepatitis B. A meta-analysis
6. Long-term remission of chronic hepatitis B after alpha-interferon therapy
7. Long-term follow-up of HBeAg-positive patients treated with interferon-α for chronic hepatitis B
8. Long-term beneficial effect of interferon therapy in patients with chronic hepatitis B virus infection
9. Natural course and response to interferon of chronic hepatitis B accompanied by antibody to hepatitis B e antigen
10. Interferon-α-2b treatment of HBeAg negative/serum HBV DNA positive chronic active hepatitis B
11. A randomized, controlled trial of a 24-month coarse of interferon-α 2b in patients with chronic hepatitis B who had hepatitis B virus DNA without hepatitis B e antigen in serum
12. Long-term alpha-interferon therapy in anti-HBe positive chronic hepatitis B increases significantly the frequency of sustained response
13. Histological grading and staging of chronic hepatitis
14. The long-term course of chronic hepatitis B
15. Survival in chronic hepatitis B. All analysis of 379 patients
16. Survival and prognostic indicators in HBsAg-positive cirrhosis of the liver
17. Survival and prognostic factors in 366 patients with compensated cirrhosis type B: A multicenter study
18. What techniques should be used for routine detection and quantification of HBV DNA in clinical samples?
19. Clinical evaluation and applications of the Amplicor HBV Monitor test. A quantitative HBV DNA PCR assay
20. Alpha interferon treatment may prevent hepatocellular carcinoma in HCV-related liver cirrhosis
21. Effect of interferon-alpha on progression of cirrhosis to hepatocellular carcinoma: A retrospective cohort study
22. Randomized trial of effects of interferon-alpha on incidence of hepatocellular-carcinoma in chronic active hepatitis-C with cirrhosis
23. Hepatitis B virus (HBV) and hepatocellular cancer
24. Clearance of HBsAg in seven patients with chronic hepatitis B
25. Hepatitis B virus integration site in hepatocellular carcinoma at chromosome 17,18 translocation
26. Structural analysis of a hepatitis B virus genome integrated into chromosome 17p of a human hepatocellular carcinoma
27. The major etiology of hepatocellular carcinoma