LKB1/PEA3/ΔNp63 pathway regulates PTGS-2 (COX-2) transcription in lung cancer cells upon cigarette smoke exposure

Oxidative Medicine and Cellular Longevity

Volumn 3, Issue 5, 2010, Pages 317-324

  Ratovitski, Edward A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer; Cell invasiveness; Cell migration; Cyclooxygenase; Inflammation; Lung; Oncogenes; Oxidative stress; P63; Smoking; Transcription; Tumor suppressors

Indexed keywords

CANCER; CELL MIGRATION; CYCLOOXYGENASES; INFLAMMATION; LUNG; ONCOGENES; P63; SMOKING; TUMOR SUPPRESSORS;

BIOLOGICAL ORGANS; CELLS; CYTOLOGY; ONCOGENIC VIRUSES; PATHOLOGY; TOBACCO; TRANSCRIPTION; TRANSCRIPTION FACTORS; TUMORS;

SMOKE;

CCAAT ENHANCER BINDING PROTEIN BETA; CIGARETTE SMOKE; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NUCLEAR FACTOR Y; PROTEIN KINASE LKB1; TRANSCRIPTION FACTOR PEA3;

ARTICLE; CANCER CELL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; LUNG CANCER CELL; MAINSTREAM SMOKE EXTRACT; PASSIVE SMOKING; PROTEIN EXPRESSION; SIDESTREAM SMOKE EXTRACT; SIGNAL TRANSDUCTION; TOBACCO; UPREGULATION;

BASE SEQUENCE; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; CYCLOOXYGENASE 2; HUMANS; LUNG NEOPLASMS; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SMOKING; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 78650746613     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.4161/oxim.3.5.13108     Document Type: Article

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