-
1
-
-
0037469146
-
Activation loop phosphorylation and catalysis in protein kinases: Is there functional evidence for the autoinhibitor model?
-
DOI 10.1021/bi020617o
-
Adams, J.A. 2003. Activation loop phosphorylation and catalysis in protein kinases: is there functional evidence for the autoinhibitor model? Biochemistry. 42:601-607. doi:10.1021/bi020617o (Pubitemid 36133283)
-
(2003)
Biochemistry
, vol.42
, Issue.3
, pp. 601-607
-
-
Adams, J.A.1
-
2
-
-
73649133646
-
Regulation of cortical contractility and spindle positioning by the protein phosphatase 6 PPH-6 in one-cell stage C elegans embryos
-
doi: 10.1242/dev.042754
-
Afshar, K., M.E. Werner, Y.C. Tse, M. Glotzer, and P. Gonczy. 2010. Regulation of cortical contractility and spindle positioning by the protein phosphatase 6 PPH-6 in one-cell stage C elegans embryos. Development. 137:237-247. doi: 10.1242/dev.042754
-
(2010)
Development
, vol.137
, pp. 237-247
-
-
Afshar, K.1
Werner, M.E.2
Tse, Y.C.3
Glotzer, M.4
Gonczy, P.5
-
3
-
-
20544449744
-
Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores
-
DOI 10.1016/j.cub.2005.05.026, PII S0960982205005154
-
Ahonen, L.J., M.J. Kallio, J.R. Daum, M. Bolton, LA. Manke, M.B. Yaffe, PT. Stukenberg, and G.J. Gorbsky. 2005. Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores. Curr. Biol. 15:1078-1089. doi:10.1016/j.cub.2005.05.026 (Pubitemid 40841350)
-
(2005)
Current Biology
, vol.15
, Issue.12
, pp. 1078-1089
-
-
Ahonen, L.J.1
Kallio, M.J.2
Daum, J.R.3
Bolton, M.4
Manke, I.A.5
Yaffe, M.B.6
Stukenberg, P.T.7
Gorbsky, G.J.8
-
4
-
-
0343917044
-
The kinase Eg2 is a component of the Xenopus oocyte progesterone- activated signaling pathway
-
DOI 10.1093/emboj/17.19.5627
-
Andresson, T., and J.V. Ruderman. 1998. The kinase Eg2 is a component of the Xenopus oocyte progesterone-activated signaling pathway. EMBO J. 17:5627-5637. doi: 10.1093/emboj/17.19.5627 (Pubitemid 28445974)
-
(1998)
EMBO Journal
, vol.17
, Issue.19
, pp. 5627-5637
-
-
Andresson, T.1
Ruderman, J.V.2
-
5
-
-
3843084078
-
The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website
-
Bamford, S., E. Dawson, S. Forbes, J. Clements, R. Pettett, A. Dogan, A. Flanagan, J. Teague, PA. Futreal, M.R. Stratton, and R. Wooster. 2004. The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website. Br. J. Cancer. 91:355-358.
-
(2004)
Br. J. Cancer
, vol.91
, pp. 355-358
-
-
Bamford, S.1
Dawson, E.2
Forbes, S.3
Clements, J.4
Pettett, R.5
Dogan, A.6
Flanagan, A.7
Teague, J.8
Futreal, P.A.9
Stratton, M.R.10
Wooster, R.11
-
6
-
-
0242330123
-
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
-
doi:10,1016/S1097-2765(03)00392-7
-
Bayliss, R., T Sardon, I. Vernos, and E. Conti. 2003. Structural basis of Aurora-A activation by TPX2 at the mitotic spindle. Mol. Cell. 12:851-862. doi:10,1016/S1097-2765(03)00392-7
-
(2003)
Mol. Cell
, vol.12
, pp. 851-862
-
-
Bayliss, R.1
Sardon, T.2
Vernos, I.3
Conti, E.4
-
7
-
-
0032100685
-
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
-
DOI 10.1093/emboj/17.11.3052
-
Bischoff, J.R., L. Anderson, Y. Zhu, K. Mossie, L. Ng, B. Souza, B. Schryver, P. Flanagan, F. Clairvoyant, C. Ginther, et al. 1998. A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. EMBO J. 17:3052-3065. doi:10.1093/emboj/17.11.3052 (Pubitemid 28254378)
-
(1998)
EMBO Journal
, vol.17
, Issue.11
, pp. 3052-3065
-
-
Bischoff, J.R.1
Anderson, L.2
Zhu, Y.3
Mossie, K.4
Ng, L.5
Souza, B.6
Schryver, B.7
Flanagan, P.8
Clairvoyant, F.9
Ginther, C.10
Chan, C.S.M.11
Novotny, M.12
Slamon, D.J.13
Plowman, G.D.14
-
8
-
-
70349333819
-
Mitotic phosphatases: From entry guards to exit guides
-
doi:10.1016/j.tcb.2009.06.005
-
Bollen, M., D.W. Gerlich, and B. Lesage. 2009. Mitotic phosphatases: from entry guards to exit guides. Trends Cell Biol. 19:531-541. doi:10.1016/j.tcb. 2009.06.005
-
(2009)
Trends Cell Biol
, vol.19
, pp. 531-541
-
-
Bollen, M.1
Gerlich, D.W.2
Lesage, B.3
-
9
-
-
33846943656
-
Multiple protein phosphatases are required for mitosis in Drosophila
-
doi:10.1016/j.cub.2007.01.068
-
Chen, F, V. Archambault, A. Kar, P. Lio', P.P. D'Avino, R. Sinka, K. Lilley, E.D. Laue, P. Deak, L. Capalbo, and D.M. Glover. 2007. Multiple protein phosphatases are required for mitosis in Drosophila. Curr. Biol. 17:293-303.doi:10.1016/j.cub.2007.01.068
-
(2007)
Curr. Biol
, vol.17
, pp. 293-303
-
-
Chen, F.1
Archambault, V.2
Kar, A.3
Lio, P.4
D'Avino, P.P.5
Sinka, R.6
Lilley, K.7
Laue, E.D.8
Deak, P.9
Capalbo, L.10
Glover, D.M.11
-
10
-
-
44349165873
-
Spatial and temporal coordination of mitosis by Ran GTPase
-
DOI 10.1038/nrm2410, PII NRM2410
-
Clarke, P.R., and C. Zhang. 2008. Spatial and temporal coordination of mitosis by Ran GTPase. Nat Rev. Mol. Cell Biol. 9:464-177. doi:10.1038/nrm2410 (Pubitemid 351733403)
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.6
, pp. 464-477
-
-
Clarke, P.R.1
Zhang, C.2
-
11
-
-
57449099865
-
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
-
doi:10.1038/nbt.1511
-
Cox, J., and M. Mann. 2008. MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat. Biotechnol. 26:1367-1372. doi:10.1038/nbt.1511
-
(2008)
Nat. Biotechnol
, vol.26
, pp. 1367-1372
-
-
Cox, J.1
Mann, M.2
-
12
-
-
29044442850
-
Lysed cell models and isolated chromosomes for the study of kinetochore/centromere biochemistry in vitro
-
Daum, J.R., and G.J. Gorbsky. 2006. Lysed cell models and isolated chromosomes for the study of kinetochore/centromere biochemistry in vitro. Methods. 38:52-59.
-
(2006)
Methods
, vol.38
, pp. 52-59
-
-
Daum, J.R.1
Gorbsky, G.J.2
-
13
-
-
0037175401
-
HNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cells
-
doi:10.1083/jcb.200208159
-
DeLuca, J.G., B. Moree, J.M. Hickey, J.V. Kilmartin, and E.D. Salmon. 2002. hNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cells. J. Cell Biol. 159:549-555. doi:10.1083/jcb.200208159
-
(2002)
J. Cell Biol
, vol.159
, pp. 549-555
-
-
Deluca, J.G.1
Moree, B.2
Hickey, J.M.3
Kilmartin, J.V.4
Salmon, E.D.5
-
14
-
-
0028214026
-
Phosphorylation and inactivation of protein phosphatase 1 by cyclin- dependent kinases
-
DOI 10.1073/pnas.91.14.6408
-
Dohadwala, M., E.F. da Cruz, E Silva, F.L. Hall, R.T. Williams, D.A. Carbonaro-Hall, A.C. Nairn, P. Greengard, and N. Berndt. 1994. Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases. Proc. Natl. Acad. Sci. USA. 91:6408-6412. doi: 10.1073/pnas.91.14.6408 (Pubitemid 24200670)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.14
, pp. 6408-6412
-
-
Dohadwala, M.1
Da Cruz Silva, E.E.F.2
Hall, F.L.3
Williams, R.T.4
Carbonaro-Hall, D.A.5
Nairn, A.C.6
Greengard, P.7
Berndt, N.8
-
15
-
-
77749334700
-
Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX
-
doi:10.1128/MCB.00741-09
-
Douglas, P., J. Zhong, R. Ye, G.B. Moorhead, X. Xu, and S.P Lees-Miller. 2010. Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX. Mol. Cell. Biol. 30:1368-1381. doi:10.1128/MCB.00741-09
-
(2010)
Mol. Cell. Biol
, vol.30
, pp. 1368-1381
-
-
Douglas, P.1
Zhong, J.2
Ye, R.3
Moorhead, G.B.4
Xu, X.5
Lees-Miller, S.P.6
-
16
-
-
41449089206
-
Spindle pole regulation by a discrete Eg5-interacting domain in TPX2
-
doi:10.1016/j.cub.2008.02.077
-
Eckerdt, F, PA. Eyers, A.L. Lewellyn, C. Prigent, and J.L. Mailer. 2008. Spindle pole regulation by a discrete Eg5-interacting domain in TPX2. Curr. Biol. 18:519-525. doi:10.1016/j.cub.2008.02.077
-
(2008)
Curr. Biol
, vol.18
, pp. 519-525
-
-
Eckerdt, F.1
Eyers, P.A.2
Lewellyn, A.L.3
Prigent, C.4
Mailer, J.L.5
-
17
-
-
1542365225
-
Regulation of Xenopus Aurora A Activation by TPX2
-
DOI 10.1074/jbc.M312424200
-
Eyers, PA., and J.L. Mailer. 2004. Regulation of Xenopus Aurora A activation by TPX2. J. Biol. Chem. 279:9008-9015. doi: 10.1074/jbc.M312424200 (Pubitemid 38295963)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.10
, pp. 9008-9015
-
-
Eyers, P.A.1
Maller, J.L.2
-
18
-
-
0037446847
-
A novel mechanism for activation of the protein kinase Aurora A
-
DOI 10.1016/S0960-9822(03)00166-0
-
Eyers, PA., E. Erikson, L.G. Chen, and J.L. Mailer. 2003. A novel mechanism for activation of the protein kinase Aurora A. Curr. Biol. 13:691-697. doi: 10.1016/S0960-9822(03)00166-0 (Pubitemid 36453320)
-
(2003)
Current Biology
, vol.13
, Issue.8
, pp. 691-697
-
-
Eyers, P.A.1
Erikson, E.2
Chen, L.G.3
Maller, J.L.4
-
19
-
-
75549087826
-
COSMIC (the Catalogue of Somatic Mutations in Cancer): A resource to investigate acquired mutations in human cancer
-
doi:10.1093/nar/gkp995
-
Forbes, S.A., G. Tang, N. Bindal, S. Bamford, E. Dawson, C. Cole, C.Y. Kok, M. Jia, R. Ewing, A. Menzies, et al. 2010. COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer. Nucleic Acids Res. 38(suppl. 1):D652-D657. doi:10.1093/nar/gkp995
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.SUPPL. 1
-
-
Forbes, S.A.1
Tang, G.2
Bindal, N.3
Bamford, S.4
Dawson, E.5
Cole, C.6
Kok, C.Y.7
Jia, M.8
Ewing, R.9
Menzies, A.10
-
20
-
-
0033591432
-
The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XlEg5
-
DOI 10.1074/jbc.274.21.15005
-
Giet, R., R. Uzbekov, F Cubizolles, K. Le Guellec, and C. Prigent. 1999. The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XlEg5. J. Biol. Chem. 274:15005-15013. doi: 10.1074/jbc.274.21.15005 (Pubitemid 29265887)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.21
, pp. 15005-15013
-
-
Giet, R.1
Uzbekov, R.2
Cubizolles, F.3
Le Guellec, K.4
Prigent, C.5
-
21
-
-
0037017398
-
Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules
-
DOI 10.1083/jcb.200108135
-
Giet, R., D. McLean, S. Descamps, M.J. Lee, J.W. Raff, C. Prigent, and D.M. Glover. 2002. Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules. J. Cell Biol. 156:437-151. doi:10.1083/jcb.200108135 (Pubitemid 34839893)
-
(2002)
Journal of Cell Biology
, vol.156
, Issue.3
, pp. 437-451
-
-
Giet, R.1
McLean, D.2
Descamps, S.3
Lee, M.J.4
Raff, J.W.5
Prigent, C.6
Glover, D.M.7
-
22
-
-
0028938482
-
Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles
-
doi: 10.1016/0092-8674(95)90374-7
-
Glover, D.M., M.H. Leibowitz, D.A. McLean, and H. Parry. 1995. Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. Cell. 81:95-105. doi: 10.1016/0092-8674(95)90374-7
-
(1995)
Cell
, vol.81
, pp. 95-105
-
-
Glover, D.M.1
Leibowitz, M.H.2
McLean, D.A.3
Parry, H.4
-
23
-
-
34247368172
-
Lining the pockets of kinases and phosphatases
-
DOI 10.1016/j.sbi.2006.10.006, PII S0959440X06001783, Catalysis and Regulation / Proteins
-
Gold, M.G., D. Barford, and D. Komander. 2006. Lining the pockets of kinases and phosphatases. Curr. Opin. Struct. Biol. 16:693-701. doi: 10.1016/j.sbi.2006.10.006 (Pubitemid 44827729)
-
(2006)
Current Opinion in Structural Biology
, vol.16
, Issue.6
, pp. 693-701
-
-
Gold, M.G.1
Barford, D.2
Komander, D.3
-
24
-
-
0038521265
-
The role of Ppe1/PP6 phosphatase for equal chromosome segregation in fission yeast kinetochore
-
DOI 10.1093/emboj/cdg266
-
Goshima, G., O. Iwasaki, C. Obuse, and M. Yanagida. 2003. The role of Ppel/PP6 phosphatase for equal chromosome segregation in fission yeast kinetochore. EMBO J. 22:2752-2763. doi: 10.1093/emboj/cdg266 (Pubitemid 36712371)
-
(2003)
EMBO Journal
, vol.22
, Issue.11
, pp. 2752-2763
-
-
Goshima, G.1
Iwasaki, O.2
Obuse, C.3
Yanagida, M.4
-
25
-
-
4444303564
-
Role of protein phosphatase type 1 in contractile functions: Myosin phosphatase
-
DOI 10.1074/jbc.R400018200
-
Hartshorne, D.J., M. Ito, andF. Erdodi. 2004. Role of protein phosphatase type 1 in contractile functions: myosin phosphatase. J. Biol. Chem. 279:37211-37214. doi:10.1074/jbc.R400018200 (Pubitemid 39195423)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.36
, pp. 37211-37214
-
-
Hartshorne, D.J.1
Ito, M.2
Erdodi, F.3
-
26
-
-
0031034680
-
Interactions of the subunits of smooth muscle myosin phosphatase
-
DOI 10.1074/jbc.272.6.3683
-
Hirano, K., B.C. Phan, and D.J. Hartshorne. 1997. Interactions of the subunits of smooth muscle myosin phosphatase. J. Biol. Chem. 272:3683-3688. doi:10.1074/jbc.272.6.3683 (Pubitemid 27066876)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.6
, pp. 3683-3688
-
-
Hirano, K.1
Phan, B.C.2
Hartshorne, D.J.3
-
27
-
-
0141429171
-
Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells
-
doi:10.1016/S0092-8674(03)00642-l
-
Hirota, T, N. Kunitoku, T Sasayama, T Marumoto, D. Zhang, M. Nitta, K. Hatakeyama, and H. Saya. 2003. Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. Cell. 114:585-598. doi:10.1016/S0092-8674(03)00642-l
-
(2003)
Cell
, vol.114
, pp. 585-598
-
-
Hirota, T.1
Kunitoku, N.2
Sasayama, T.3
Marumoto, T.4
Zhang, D.5
Nitta, M.6
Hatakeyama, K.7
Saya, H.8
-
28
-
-
0037013143
-
The conformational plasticity of protein kinases
-
DOI 10.1016/S0092-8674(02)00741-9
-
Huse, M., and J. Kuriyan. 2002. The conformational plasticity of protein kinases. Cell. 109:275-282. doi:10.1016/S0092-8674(02)00741-9 (Pubitemid 34606870)
-
(2002)
Cell
, vol.109
, Issue.3
, pp. 275-282
-
-
Huse, M.1
Kuriyan, J.2
-
29
-
-
33746544622
-
Mitotic Activation of the Kinase Aurora-A Requires Its Binding Partner Bora
-
DOI 10.1016/j.devcel.2006.06.002, PII S1534580706002589
-
Hutterer, A., D. Berdnik, F Wirtz-Peitz, M. Zigman, A. Schleiffer, and J.A. Knoblich 2006. Mitotic activation of the kinase Aurora-A requires its binding partner Bova. Dev. Cell. 11:147-157. doi:10.1016/j.devcel.2006.06.002 (Pubitemid 44138495)
-
(2006)
Developmental Cell
, vol.11
, Issue.2
, pp. 147-157
-
-
Hutterer, A.1
Berdnik, D.2
Wirtz-Peitz, F.3
Zigman, M.4
Schleiffer, A.5
Knoblich, J.A.6
-
30
-
-
0037113919
-
Phosphorylation of threonine 210 and the role of serine 137 in the regulation of mammalian polo-like kinase
-
DOI 10.1074/jbc.M202172200
-
Jang, YJ., S. Ma, Y Terada, and R.L. Erikson. 2002. Phosphorylation of threonine 210 and the role of serine 137 in the regulation of mammalian polo-like kinase. J. Biol. Chem. 277:44115-44120. doi:10.1074/jbc.M202172200 (Pubitemid 36157840)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.46
, pp. 44115-44120
-
-
Jang, Y.-J.1
Ma, S.2
Terada, Y.3
Erikson, R.L.4
-
31
-
-
0030036564
-
Identification of protein-phosphatase-1-binding domains on the glycogen and myofibrillar targetting subunits
-
doi:10.1111/j.l432-1033.1996.0317u.x
-
Johnson, D.F, G. Moorhead, FB. Caudwell, P. Cohen, YH. Chen, M.X. Chen, and P.T. Cohen. 1996. Identification of protein-phosphatase-1-binding domains on the glycogen and myofibrillar targetting subunits. Eur. J. Biochem. 239:317-325. doi:10.1111/j.l432-1033.1996.0317u.x
-
(1996)
Eur. J. Biochem
, vol.239
, pp. 317-325
-
-
Johnson, D.F.1
Moorhead, G.2
Caudwell, F.B.3
Cohen, P.4
Chen, Y.H.5
Chen, M.X.6
Cohen, P.T.7
-
32
-
-
0023619919
-
Sequence homologies between type 1 and type 2A protein phosphatases
-
doi:10.1210/mend-l-10-745
-
Johnson, G.L., D.L. Brautigan, C. Shriner, S. Jaspers, J. Arino, J.E. Mole, T.B. Miller Jr., and M.C. Mumby. 1987. Sequence homologies between type 1 and type 2A protein phosphatases. Mol. Endocrinol. 1:745-748. doi:10.1210/mend-l-10-745
-
(1987)
Mol. Endocrinol
, vol.1
, pp. 745-748
-
-
Johnson, G.L.1
Brautigan, D.L.2
Shriner, C.3
Jaspers, S.4
Arino, J.5
Mole, J.E.6
Miller Jr., T.B.7
Mumby, M.C.8
-
33
-
-
78649507729
-
Biology of Aurora A kinase: Implications in cancer manifestation and therapy
-
Karthigeyan, D., S.B. Prasad, J. Shandilya, S. Agrawal, and T.K. Kundu. 2010. Biology of Aurora A kinase: Implications in cancer manifestation and therapy. Med. Res. Rev.
-
(2010)
Med. Res. Rev
-
-
Karthigeyan, D.1
Prasad, S.B.2
Shandilya, J.3
Agrawal, S.4
Kundu, T.K.5
-
34
-
-
25444493845
-
Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis
-
DOI 10.1083/jcb.200503023
-
Kinoshita, K., T.L. Noetzel, L. Pelletier, K. Mechtler, D.N. Drechsel, A. Schwager, M. Lee, J.W. Raff, and A.A. Hyman. 2005. Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis. J. Cell Biol. 170:1047-1055. doi: 10.1083/jcb.200503023 (Pubitemid 41362637)
-
(2005)
Journal of Cell Biology
, vol.170
, Issue.7
, pp. 1047-1055
-
-
Kinoshita, K.1
Noetzel, T.L.2
Pelletier, L.3
Mechtler, K.4
Drechsel, D.N.5
Schwager, A.6
Lee, M.7
Raff, J.W.8
Hyman, A.A.9
-
35
-
-
33646795889
-
Shugoshin collaborates with protein phosphatase 2A to protect cohesin
-
doi:10.1038/nature04663
-
Kitajima, T.S., T Sakuno, K. Ishiguro, S. Iemura, T Natsume, S.A. Kawashima, and Y Watanabe. 2006. Shugoshin collaborates with protein phosphatase 2A to protect cohesin. Nature. 441:46-52. doi:10.1038/nature04663
-
(2006)
Nature
, vol.441
, pp. 46-52
-
-
Kitajima, T.S.1
Sakuno, T.2
Ishiguro, K.3
Iemura, S.4
Natsume, T.5
Kawashima, S.A.6
Watanabe, Y.7
-
36
-
-
70349780568
-
Alpha4 is an essential regulator of PP2A phosphatase activity
-
doi:10.1016/j.molcel.2009.09.025
-
Kong, M., D. Ditsworth, T Lindsten, and C.B. Thompson. 2009. Alpha4 is an essential regulator of PP2A phosphatase activity. Mol. Cell. 36:51-60. doi:10.1016/j.molcel.2009.09.025
-
(2009)
Mol. Cell
, vol.36
, pp. 51-60
-
-
Kong, M.1
Ditsworth, D.2
Lindsten, T.3
Thompson, C.B.4
-
37
-
-
0037135979
-
Human TPX2 is required for targeting Aurora-A kinase to the spindle
-
DOI 10.1083/jcb.200204155
-
Kufer, T.A., H.H. Sillje, R. Korner, O.J. Gruss, P. Meraldi, and E.A. Nigg. 2002. Human TPX2 is required for targeting Aurora-A kinase to the spindle. J. Cell Biol. 158:617-623. doi: 10.1083/jcb.200204155 (Pubitemid 34920101)
-
(2002)
Journal of Cell Biology
, vol.158
, Issue.4
, pp. 617-623
-
-
Kufer, T.A.1
Sillje, H.H.W.2
Korner, R.3
Gruss, O.J.4
Meraldi, P.5
Nigg, E.A.6
-
38
-
-
12644291188
-
Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase
-
doi:10,1073/pnas.94.6.2168
-
Kwon, Y.G., S.Y Lee, Y Choi, P. Greengard, and A.C. Nairn. 1997. Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase. Proc. Natl. Acad. Sci. USA. 94:2168-2173. doi:10,1073/pnas.94.6.2168
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2168-2173
-
-
Kwon, Y.G.1
Lee, S.Y.2
Choi, Y.3
Greengard, P.4
Nairn, A.C.5
-
39
-
-
0030462914
-
Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plkl) in the functional maturation of mitotic centrosomes
-
doi: 10.1083/jcb. 135.6.1701
-
Lane, H.A., and E.A. Nigg. 1996. Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plkl) in the functional maturation of mitotic centrosomes. J. Cell Biol. 135:1701-1713. doi: 10.1083/jcb. 135.6.1701
-
(1996)
J. Cell Biol
, vol.135
, pp. 1701-1713
-
-
Lane, H.A.1
Nigg, E.A.2
-
40
-
-
0025840258
-
Polo encodes a protein kinase homolog required for mitosis in Drosophila
-
doi:10.1101/gad.5.12a.2153
-
Llamazares, S., A. Moreira, A. Tavares, C. Girdham, B.A. Spruce, C. Gonzalez, R.E. Karess, D.M. Glover, and C.E. Sunkel. 1991. polo encodes a protein kinase homolog required for mitosis in Drosophila. Genes Dev 5:2153-2165. doi:10.1101/gad.5.12a.2153
-
(1991)
Genes Dev
, vol.5
, pp. 2153-2165
-
-
Llamazares, S.1
Moreira, A.2
Tavares, A.3
Girdham, C.4
Spruce, B.A.5
Gonzalez, C.6
Karess, R.E.7
Glover, D.M.8
Sunkel, C.E.9
-
41
-
-
66149091940
-
A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene
-
doi: 10.1016/j.cell.2009.05.006
-
Luo, J., M.J. Emanuele, D. Li, C.J. Creighton, M.R. Schlabach, T.K Westbrook, K.K. Wong, and S.J. Elledge. 2009. A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. Cell. 137:835-848. doi: 10.1016/j.cell.2009.05.006
-
(2009)
Cell
, vol.137
, pp. 835-848
-
-
Luo, J.1
Emanuele, M.J.2
Li, D.3
Creighton, C.J.4
Schlabach, M.R.5
Westbrook, T.K.6
Wong, K.K.7
Elledge, S.J.8
-
42
-
-
34247259822
-
Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora a kinase
-
DOI 10.1073/pnas.0608798104
-
Manfredi, M.G., J.A. Ecsedy, K.A. Meetze, S.K. Balani, O. Burenkova, W. Chen, K.M. Galvin, K.M. Hoar, J.J. Huck, P.J. LeRoy, et al. 2007. Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase. Proc. Natl. Acad. Sci. USA. 104:4106-4111. doi:10.1073/pnas.0608798104 (Pubitemid 47181586)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.10
, pp. 4106-4111
-
-
Manfredi, M.G.1
Ecsedy, J.A.2
Meetze, K.A.3
Balani, S.K.4
Burenkova, O.5
Chen, W.6
Galvin, K.M.7
Hoar, K.M.8
Huck, J.J.9
LeRoy, P.J.10
Ray, E.T.11
Sells, T.B.12
Stringer, B.13
Stroud, S.G.14
Vos, T.J.15
Weatherhead, G.S.16
Wysong, D.R.17
Zhang, M.18
Bolen, J.B.19
Claiborne, C.F.20
more..
-
43
-
-
84887212592
-
Activation of DNA-PK by ionizing radiation is mediated by protein phosphatase 6
-
doi:10.1371/journal.pone.0004395
-
Mi, J., J. Dziegielewski, E. Bolesta, D.L. Brautigan, and J.M. Lamer. 2009. Activation of DNA-PK by ionizing radiation is mediated by protein phosphatase 6. PLoS One. 4:e4395. doi:10.1371/journal.pone.0004395
-
(2009)
PLoS One
, vol.4
-
-
Mi, J.1
Dziegielewski, J.2
Bolesta, E.3
Brautigan, D.L.4
Lamer, J.M.5
-
44
-
-
0035235736
-
Mitotic kinases as regulators of cell division and its checkpoints
-
DOI 10.1038/35048096
-
Nigg, E.A. 2001. Mitotic kinases as regulators of cell division and its checkpoints. Nat Rev. Mol. Cell Biol. 2:21-32. doi: 10.1038/35048096 (Pubitemid 33676958)
-
(2001)
Nature Reviews Molecular Cell Biology
, vol.2
, Issue.1
, pp. 21-32
-
-
Nigg, E.A.1
-
45
-
-
33845697790
-
Phospho-regulation of human protein kinase Aurora-A: Analysis using anti-phospho-Thr288 monoclonal antibodies
-
doi:10.1038/sj.one.1209754
-
Ohashi, S., G. Sakashita, R. Ban, M. Nagasawa, H. Matsuzaki, Y Murata, H. Taniguchi, H. Shima, K. Furukawa, and T Urano. 2006. Phospho-regulation of human protein kinase Aurora-A: analysis using anti-phospho-Thr288 monoclonal antibodies. Oncogene. 25:7691-7702. doi:10.1038/sj.one. 1209754
-
(2006)
Oncogene
, vol.25
, pp. 7691-7702
-
-
Ohashi, S.1
Sakashita, G.2
Ban, R.3
Nagasawa, M.4
Matsuzaki, H.5
Murata, Y.6
Taniguchi, H.7
Shima, H.8
Furukawa, K.9
Urano, T.10
-
46
-
-
22944481829
-
An essential function of the C. elegans ortholog of TPX2 is to localize activated Aurora A Kinase to Mitotic Spindles
-
DOI 10.1016/j.devcel.2005.07.002, PII S1534580705002534
-
Ozlti, N., M. Srayko, K. Kinoshita, B. Habermann, E.T. O'Toole, T Mtiller-Reichert, N. Schmalz, A. Desai, and A.A. Hyman. 2005. An essential function of the C elegans ortholog of TPX2 is to localize activated aurora A kinase to mitotic spindles. Dev. Cell. 9:237-248. doi: 10.1016/j.devcel.2005.07. 002 (Pubitemid 41051742)
-
(2005)
Developmental Cell
, vol.9
, Issue.2
, pp. 237-248
-
-
Ozlu, N.1
Srayko, M.2
Kinoshita, K.3
Habermann, B.4
O'Toole, E.T.5
Muller-Reichert, T.6
Schmalz, N.7
Desai, A.8
Hyman, A.A.9
-
47
-
-
15444380728
-
Plk1 docking to GRASP65 phosphorylated by Cdk1 suggests a mechanism for Golgi checkpoint signalling
-
DOI 10.1038/sj.emboj.7600569
-
Preisinger, C, R. Korner, M. Wind, WD. Lehmann, R. Kopajtich, and FA. Barr. 2005. Plkl docking to GRASP65 phosphorylated by Cdkl suggests a mechanism for Golgi checkpoint signalling. EMBO J. 24:753-765. doi: 10.1038/sj.emboj. 7600569 (Pubitemid 40396105)
-
(2005)
EMBO Journal
, vol.24
, Issue.4
, pp. 753-765
-
-
Preisinger, C.1
Korner, R.2
Wind, M.3
Lehmann, W.D.4
Kopajtich, R.5
Barr, F.A.6
-
48
-
-
33750076984
-
The α4 regulatory subunit exerts opposing allosteric effects on protein phosphatases PP6 and PP2A
-
DOI 10.1074/jbc.M601054200
-
Prickett, T.D., and D.L. Brautigan. 2006. The alpha4 regulatory subunit exerts opposing allosteric effects on protein phosphatases PP6 and PP2A. J. Biol. Chem. 281:30503-30511. doi:10.1074/jbc.M601054200 (Pubitemid 44582107)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.41
, pp. 30503-30511
-
-
Prickett, T.D.1
Brautigan, D.L.2
-
49
-
-
0031938231
-
The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly
-
Roghi, C, R. Giet, R. Uzbekov, N. Morin, I. Chartrain, R. Le Guellec, A. Couturier, M. Doree, M. Philippe, and C. Prigent. 1998. The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly. J. Cell Sci. 111:557-572.
-
(1998)
J. Cell Sci
, vol.111
, pp. 557-572
-
-
Roghi, C.1
Giet, R.2
Uzbekov, R.3
Morin, N.4
Chartrain, I.5
Le Guellec, R.6
Couturier, A.7
Doree, M.8
Philippe, M.9
Prigent, C.10
-
50
-
-
2942590333
-
Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein
-
DOI 10.1073/pnas.0402966101
-
Satinover, D.L., C.A. Leach, P.T. Stukenberg, and D.L. Brautigan. 2004. Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bi-functional signaling protein. Proc. Natl. Acad. Sci. USA. 101:8625-8630. doi:10.1073/pnas.0402966101 (Pubitemid 38745821)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.23
, pp. 8625-8630
-
-
Satinover, D.L.1
Leach, C.A.2
Stukenberg, P.T.3
Brautigan, D.L.4
-
51
-
-
0030962953
-
A putative serine/threonine kinase encoding gene BTAK on chromosome 20ql3 is amplified and over-expressed in human breast cancer cell lines
-
doi: 10.1038/sj.onc. 1201065
-
Sen, S., H. Zhou, and R.A. White. 1997. A putative serine/threonine kinase encoding gene BTAK on chromosome 20ql3 is amplified and over-expressed in human breast cancer cell lines. Oncogene. 14:2195-2200. doi: 10.1038/sj.onc. 1201065
-
(1997)
Oncogene
, vol.14
, pp. 2195-2200
-
-
Sen, S.1
Zhou, H.2
White, R.A.3
-
52
-
-
20844436307
-
Mechanism of Aurora B activation by INCENP and inhibition by hesperadin
-
DOI 10.1016/j.molcel.2005.03.031, PII S1097276505012244
-
Sessa, F, M. Mapelli, C. Ciferri, C. Tarricone, L.B. Areces, T.R. Schneider, P.T Stukenberg, and A. Musacchio. 2005. Mechanism of Aurora B activation by INCENP and inhibition by hesperadin. Mol. Cell. 18:379-391. doi:10.1016/j.molcel.2005.03.031 (Pubitemid 41350542)
-
(2005)
Molecular Cell
, vol.18
, Issue.3
, pp. 379-391
-
-
Sessa, F.1
Mapelli, M.2
Ciferri, C.3
Tarricone, C.4
Areces, L.B.5
Schneider, T.R.6
Stukenberg, P.T.7
Musacchio, A.8
-
53
-
-
70350340056
-
Serine/threonine phosphatases: Mechanism through structure
-
doi: 10.1016/j.cell.2009.10.006
-
Shi, Y 2009. Serine/threonine phosphatases: mechanism through structure. Cell. 139:468-184. doi: 10.1016/j.cell.2009.10.006
-
(2009)
Cell
, vol.139
, pp. 468-184
-
-
Shi, Y.1
-
54
-
-
33747334635
-
Protein phosphatase 6 subunit with conserved Sit4-associated protein domain targets IkappaBepsilon
-
doi:10.1074/jbc.M601772200
-
Stefansson, B., and D.L. Brautigan. 2006. Protein phosphatase 6 subunit with conserved Sit4-associated protein domain targets IkappaBepsilon. J. Biol. Chem. 281:22624-22634. doi:10.1074/jbc.M601772200
-
(2006)
J. Biol. Chem
, vol.281
, pp. 22624-22634
-
-
Stefansson, B.1
Brautigan, D.L.2
-
55
-
-
38849182807
-
Protein phosphatase 6 regulatory subunits composed of ankyrin repeat domains
-
DOI 10.1021/bi7022877
-
Stefansson, B., T. Ohama, A.E. Daugherty, and D.L. Brautigan. 2008. Protein phosphatase 6 regulatory subunits composed of ankyrin repeat domains. Biochemistry. 47:1442-1451. doi:10.1021/bi7022877 (Pubitemid 351198719)
-
(2008)
Biochemistry
, vol.47
, Issue.5
, pp. 1442-1451
-
-
Stefansson, B.1
Ohama, T.2
Daugherty, A.E.3
Brautigan, D.L.4
-
56
-
-
33646098667
-
PP2A is required for centromeric localization of Sgol and proper chromosome segregation
-
doi:10.1016/j.devcel.2006.03.010
-
Tang, Z., H. Shu, W. Qi, N.A. Mahmood, M.C. Mumby, and H. Yu. 2006. PP2A is required for centromeric localization of Sgol and proper chromosome segregation. J. Cell. 10:575-585. doi:10.1016/j.devcel.2006.03.010
-
(2006)
J. Cell
, vol.10
, pp. 575-585
-
-
Tang, Z.1
Shu, H.2
Qi, W.3
Mahmood, N.A.4
Mumby, M.C.5
Yu, H.6
-
57
-
-
3042547846
-
Structural basis of protein phosphatase 1 regulation
-
doi:10,1038/nature02582
-
Terrak, M., F. Kerff, K. Langsetmo, T. Tao, and R. Dominguez. 2004. Structural basis of protein phosphatase 1 regulation. Nature. 429:780-784. doi:10,1038/nature02582
-
(2004)
Nature
, vol.429
, pp. 780-784
-
-
Terrak, M.1
Kerff, F.2
Langsetmo, K.3
Tao, T.4
Dominguez, R.5
-
58
-
-
0000606386
-
Study of the subunit interactions in myosin phosphatase by surface plasmon resonance
-
DOI 10.1046/j.1432-1327.2000.01158.x
-
Toth, A., E. Kiss, F.W. Herberg, P. Gergely, D.J. Hartshorne, and F. Erdodi. 2000. Study of the subunit interactions in myosin phosphatase by surface plas-mon resonance. Eur. J. Biochem. 267:1687-1697. doi:10.1046/J.1432-1327. 2000.01158.x (Pubitemid 30165522)
-
(2000)
European Journal of Biochemistry
, vol.267
, Issue.6
, pp. 1687-1697
-
-
Toth, A.1
Kiss, E.2
Herberg, F.W.3
Gergely, P.4
Hartshorne, D.J.5
Erdodi, F.6
-
59
-
-
0037341906
-
A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly
-
DOI 10.1038/ncb936
-
Tsai, M.Y., C. Wiese, K. Cao, O. Martin, P. Donovan, J. Ruderman, C. Prigent, and Y. Zheng. 2003. A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly. Nat. Cell Biol. 5:242-248. doi:10.1038/ncb936 (Pubitemid 36322252)
-
(2003)
Nature Cell Biology
, vol.5
, Issue.3
, pp. 242-248
-
-
Tsai, M.-Y.1
Wiese, C.2
Cao, K.3
Martin, O.4
Donovan, P.5
Ruderman, J.6
Prigent, C.7
Zheng, Y.8
-
60
-
-
33749186913
-
Condensin and Repo-Man-PPl co-operate in the regulation of chromosome architecture during mitosis
-
doi:10.1038/ncbl475
-
Vagnarelli, P., D.F Hudson, S.A. Ribeiro, L. Trinkle-Mulcahy, J.M. Spence, F Lai, C.J. Farr, A.I. Lamond, and W.C. Earnshaw. 2006. Condensin and Repo-Man-PPl co-operate in the regulation of chromosome architecture during mitosis. Nat Cell Biol. 8:1133-1142. doi:10.1038/ncbl475
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1133-1142
-
-
Vagnarelli, P.1
Hudson, D.F.2
Ribeiro, S.A.3
Trinkle-Mulcahy, L.4
Spence, J.M.5
Lai, F.6
Farr, C.J.7
Lamond, A.I.8
Earnshaw, W.C.9
-
61
-
-
0034609753
-
The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation
-
doi: 10.1038/sj.one. 1203847
-
Walter, A.O., W. Seghezzi, W. Korver, J. Sheung, and E. Lees. 2000. The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation. Oncogene. 19:4906-4916. doi: 10.1038/sj.one. 1203847
-
(2000)
Oncogene
, vol.19
, pp. 4906-4916
-
-
Walter, A.O.1
Seghezzi, W.2
Korver, W.3
Sheung, J.4
Lees, E.5
-
62
-
-
0030026070
-
Femtomole sequencing of proteins from polyacrylamide by nano-electrospray mass spectromtry
-
DOI 10.1038/379466a0
-
Wilm, M., A. Shevchenko, T. Houthaeve, S. Breit, L. Schweigerer, T. Fotsis, and M. Mann. 1996. Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry. Nature. 379:466-469. doi: 10.1038/379466a0 (Pubitemid 26039530)
-
(1996)
Nature
, vol.379
, Issue.6564
, pp. 466-469
-
-
Wilm, M.1
Shevchenko, A.2
Houthaeve, T.3
Breit, S.4
Schweigerer, L.5
Fotsis, T.6
Mann, M.7
-
63
-
-
33750006297
-
Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins
-
doi:10,1016/j.cell.2006.09.025
-
Xing, Y, Y Xu, Y Chen, PD. Jeffrey, Y Chao, Z. Lin, Z. Li, S. Strack, J.B. Stock, and Y Shi. 2006. Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins. Cell. 127:341-353. doi:10,1016/j.cell.2006.09. 025
-
(2006)
Cell
, vol.127
, pp. 341-353
-
-
Xing, Y.1
Xu, Y.2
Chen, Y.3
Jeffrey, P.D.4
Chao, Y.5
Lin, Z.6
Li, Z.7
Strack, S.8
Stock, J.B.9
Shi, Y.10
-
64
-
-
43049101715
-
Myosin Phosphatase-Targeting Subunit 1 Regulates Mitosis by Antagonizing Polo-like Kinase 1
-
DOI 10.1016/j.devcel.2008.02.013, PII S153458070800107X
-
Yamashiro, S., Y Yamakita, G. Totsukawa, H. Goto, K. Kaibuchi, M. Ito, D.J. Hartshorne, and F Matsumura. 2008. Myosin phosphatase-targeting sub-unit 1 regulates mitosis by antagonizing polo-like kinase 1. Dev. Cell. 14:787-797. doi:10.1016/j.devcel.2008.02.013 (Pubitemid 351622611)
-
(2008)
Developmental Cell
, vol.14
, Issue.5
, pp. 787-797
-
-
Yamashiro, S.1
Yamakita, Y.2
Totsukawa, G.3
Goto, H.4
Kaibuchi, K.5
Ito, M.6
Hartshorne, D.J.7
Matsumura, F.8
-
65
-
-
26944442735
-
The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A
-
DOI 10.1016/j.molcel.2005.08.035, PII S1097276505016011
-
Zhao, Z.S., J.R Lim, YW. Ng, L. Lim, and E. Manser. 2005. The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A. Mol. Cell. 20:237-249. doi:10.1016/j.molcel.2005.08.035 (Pubitemid 41484169)
-
(2005)
Molecular Cell
, vol.20
, Issue.2
, pp. 237-249
-
-
Zhao, Z.-S.1
Lim, J.P.2
Ng, Y.-W.3
Lim, L.4
Manser, E.5
-
66
-
-
0031714080
-
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
-
DOI 10.1038/2496
-
Zhou, H., J. Kuang, L. Zhong, W.L. Kuo, J.W. Gray, A. Sahin, B.R. Brinkley, and S. Sen. 1998. Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat. Genet. 20:189-193. doi: 10.1038/2496 (Pubitemid 28455454)
-
(1998)
Nature Genetics
, vol.20
, Issue.2
, pp. 189-193
-
-
Zhou, H.1
Kuang, J.2
Zhong, L.3
Kuo, W.-L.4
Gray, J.W.5
Sahin, A.6
Brinkley, B.R.7
Sen, S.8
|